Consider drug efficacy before first-in-human trials

Nature

Volumn 542, Issue 7639, 2017, Pages 25-27

  Kimmelman, Jonathan ^a   Federico, Carole ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

DRUG EFFICACY; DRUG SAFETY; ETHICS; EXPERIMENTAL THERAPY; FIRST IN HUMAN STUDY; FOOD AND DRUG ADMINISTRATION; HUMAN; NOTE; PRACTICE GUIDELINE; PRECLINICAL STUDY; PRIORITY JOURNAL; STANDARD; ANIMAL; ANIMAL MODEL; CLINICAL TRIAL (TOPIC); DOSE RESPONSE; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; ECONOMICS; FRANCE; MALE; METHODOLOGY; MOUSE; NORMAL HUMAN; ORGANIZATION AND MANAGEMENT; PATIENT SAFETY; PROCEDURES; RESEARCH ETHICS; RISK ASSESSMENT; STANDARDS; TREATMENT FAILURE; UNITED STATES;

ANIMALS; CLINICAL TRIALS AS TOPIC; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; ETHICS, RESEARCH; FRANCE; HEALTHY VOLUNTEERS; HUMANS; MALE; MICE; MODELS, ANIMAL; PATIENT SAFETY; RESEARCH DESIGN; RISK ASSESSMENT; TREATMENT FAILURE; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 85011995455     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/542025a     Document Type: Note

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