Initiation of the yeast G0 program requires Igo1 and Igo2, which antagonize activation of decapping of specific nutrient-regulated mRNAs

RNA Biology

Volumn 8, Issue 1, 2011, Pages

  Luo, Xuan ^a   Talarek, Nicolas ^a   De Virgilio, Claudio ^a  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

Author keywords

5 3 mRNA decay pathway; Igo1 and igo2; mRNA stability; Quiescence; TORC1; Yeast

Indexed keywords

CARBON; CYCLIC AMP DEPENDENT PROTEIN KINASE; GENE PRODUCT; HYBRID PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; NITROGEN; PROTEIN CCR4; PROTEIN DHH1; PROTEIN IGO1; PROTEIN IGO2; PROTEIN KINASE; PROTEIN LSM PAT1; UNCLASSIFIED DRUG; CCR4 PROTEIN, S CEREVISIAE; CELL CYCLE PROTEIN; DEAD BOX PROTEIN; DHH1 PROTEIN, S CEREVISIAE; DNA BINDING PROTEIN; FUNGAL RNA; HEAT SHOCK PROTEIN; HSP26 PROTEIN, S CEREVISIAE; IGO1 PROTEIN, S CEREVISIAE; IGO2 PROTEIN, S CEREVISIAE; MRNA DECAPPING ENZYMES; MSN2 PROTEIN, S CEREVISIAE; MSN4 PROTEIN, S CEREVISIAE; RIBONUCLEASE; RIM15 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSCRIPTION FACTOR;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; CELL CYCLE G0 PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DEGRADATION; DOWN REGULATION; EUKARYOTE; GENETIC TRANSCRIPTION; NONHUMAN; NUTRIENT; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; REVIEW; RNA DEGRADATION; SIGNAL TRANSDUCTION; YEAST; ARTICLE; CHEMICAL STRUCTURE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; RNA STABILITY; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION;

EUKARYOTA;

CELL CYCLE PROTEINS; DEAD-BOX RNA HELICASES; DNA-BINDING PROTEINS; ENDORIBONUCLEASES; G0 PHASE; GENE EXPRESSION REGULATION, FUNGAL; HEAT-SHOCK PROTEINS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN KINASES; RIBONUCLEASES; RNA STABILITY; RNA, FUNGAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 85011936069     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.8.1.13483     Document Type: Review

References (26)

1. De Virgilio C, Loewith R. The TOR signalling network from yeast to man. Int J Biochem Cell Biol 2006; 38:1476-81.
2. De Virgilio C, Loewith R. Cell growth control: little eukaryotes make big contributions. Oncogene 2006; 25:6392-415. (Pubitemid 44582284)
3. Powers RW, 3rd, Kaeberlein M, Caldwell SD, Kennedy BK, Fields S. Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev 2006; 20:174-84.
4. Kaeberlein M, Burtner CR, Kennedy BK. Recent developments in yeast aging. PLoS Genet 2007; 3:84.
5. Reinders A, Bürckert N, Boller T, Wiemken A, De Virgilio C. Saccharomyces cerevisiae cAMP-dependent protein kinase controls entry into stationary phase through the Rim15p protein kinase. Genes Dev 1998; 12:2943-55.
6. Fabrizio P, Pozza F, Pletcher SD, Gendron CM, Longo VD. Regulation of longevity and stress resistance by Sch9 in yeast. Science 2001; 292:288-90. (Pubitemid 32295387)
7. Wei M, Fabrizio P, Hu J, Ge H, Cheng C, Li L, et al. Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor and Sch9. PLoS Genet 2008; 4:13.
8. 0 entry by the Pho80-Pho85 cyclin-CDK complex. EMBO J 2005; 24:4271-8.
9. 0. Mol Cell 2003; 12:1607-13.
10. Wanke V, Cameroni E, Uotila A, Piccolis M, Urban J, Loewith R, et al. Caffeine extends yeast lifespan by targeting TORC1. Mol Microbiol 2008; 69:277-85. (Pubitemid 351832771)
11. Jorgensen P, Rupes I, Sharom JR, Schneper L, Broach JR, Tyers M. A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes Dev 2004; 18:2491-505. (Pubitemid 39362892)
12. Urban J, Soulard A, Huber A, Lippman S, Mukhopadhyay D, Deloche O, et al. Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Mol Cell 2007; 26:663-74.
13. Pedruzzi I, Bürckert N, Egger P, De Virgilio C. Saccharomyces cerevisiae Ras/cAMP pathway controls post-diauxic shift element-dependent transcription through the zinc finger protein Gis1. EMBO J 2000; 19:2569-79.
14. 0-associated antioxidant defense mechanisms. Cell Cycle 2004; 3:462-8.
15. 0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5′-3′ mRNA decay pathway. Mol Cell 2010; 38:345-55.
16. Swisher KD, Parker R. Localization to and effects of Pbp1, Pbp4, Lsm12, Dhh1 and Pab1 on stress granules in Saccharomyces cerevisiae. PLoS One 2010; 5:10006.
17. Mangus DA, Smith MM, McSweeney JM, Jacobson A. Identification of factors regulating poly(A) tail synthesis and maturation. Mol Cell Biol 2004; 24:4196-206. (Pubitemid 41070993)
18. Keppler-Ross S, Noffz C, Dean N. A new purple fluorescent color marker for genetic studies in Saccharomyces cerevisiae and Candida albicans. Genetics 2008; 179:705-10.
19. Tong AH, Evangelista M, Parsons AB, Xu H, Bader GD, Page N, et al. Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 2001; 294:2364-8. (Pubitemid 33140562)
20. Parker R, Sheth U. P bodies and the control of mRNA translation and degradation. Mol Cell 2007; 25:635-46. (Pubitemid 46341926)
21. Franks TM, Lykke-Andersen J. The control of mRNA decapping and P-body formation. Mol Cell 2008; 32:605-15.
22. Ozgur S, Chekulaeva M, Stoecklin G. Human Pat1b Connects Deadenylation with mRNA Decapping and Controls the Assembly of Processing-Bodies. Mol Cell Biol 2010; In press.
23. Braun JE, Tritschler F, Haas G, Igreja C, Truffault V, Weichenrieder O, et al. The C-terminal α-α superhelix of Pat is required for mRNA decapping in metazoa. EMBO J 2010.
24. Fischer N, Weis K. The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1. EMBO J 2002; 21:2788-97.
25. Irwin N, Chao S, Goritchenko L, Horiuchi A, Greengard P, Nairn AC, et al. Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19. Proc Natl Acad Sci USA 2002; 99:12427-31.
26. Griffioen G, Anghileri P, Imre E, Baroni MD, Ruis H. Nutritional control of nucleocytoplasmic localization of cAMP-dependent protien kinase catalytic and regulatory subunits in Saccharomyces cerevisiae. J Biol Chem 2000; 275:1449-56. (Pubitemid 30051205)