Insulin-like growth factor 1 and risk of depression in older people: The English Longitudinal Study of Ageing

Translational Psychiatry

Volumn 6, Issue 9, 2016, Pages

  Chigogora, S ^a   Zaninotto, P ^a   Kivimaki, M ^a   Steptoe, A ^a   Batty, G D ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C; IGF1 PROTEIN, HUMAN;

ADULT; AGED; AGING; ARTICLE; BLOOD LEVEL; DEPRESSION; FEMALE; FOLLOW UP; HEALTH BEHAVIOR; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MORBIDITY; SELF REPORT; SOCIAL STATUS; COMORBIDITY; CROSS-SECTIONAL STUDY; ENGLAND; METABOLISM; MIDDLE AGED; ODDS RATIO; PROTECTION; PSYCHOLOGY; SOCIAL CLASS;

AGED; AGING; COMORBIDITY; CROSS-SECTIONAL STUDIES; DEPRESSION; DEPRESSIVE DISORDER; ENGLAND; FEMALE; HEALTH BEHAVIOR; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; ODDS RATIO; PROTECTIVE FACTORS; SOCIAL CLASS;

EID: 85011891875     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2016.167     Document Type: Article

References (56)

1. World Health Organization. Depression, Fact sheet No. 369, October 2012. Available at http://www.who.int/mediacentre/factsheets/fs369/en/[accessed 23 January 2015].
2. World Health Organization. The Global Burden of Disease: 2004 Update. World Health Organization: Geneva, Switzerland, 2008.
3. Isometsä E, Henriksson M, Marttunen M, Heikkinen M, Aro H, Kuoppasalmi K et al. Mental disorders in young and middle aged men who commit suicide. BMJ 1995; 310: 1366-1367.
4. Bell S, Russ TC, Kivimäki M, Stamatakis E, Batty GD. Dose-response association between psychological distress and risk of completed suicide in the general population. JAMA Psychiatry 2015; 11: 1-3.
5. Pan A, Sun Q, Okereke OI, Rexrode KM, Hu FB. Depression and risk of stroke morbidity and mortality: A meta-analysis and systematic review. JAMA 2011; 306: 1241-1249.
6. Daskalopoulou M, George J, Walters K, Osborn DP, Batty GD, Stogiannis D et al. Depression as a risk factor for the initial presentation of twelve cardiac, cerebrovascular, and peripheral arterial diseases: data linkage study of 1.9 million women and men. PLoS One 2016; 11: e0153838.
7. Nicholson A, Kuper H, Hemingway H. Depression as an aetiologic and prognostic factor in coronary heart disease: A meta-analysis of 6362 events among 146 538 participants in 54 observational studies. Eur Heart J 2006; 27: 2763-2774.
8. Currier MB, Nemeroff CB. Depression as a risk factor for cancer: from pathophysiological advances to treatment implications. Annu Rev Med 2014; 65: 203-221.
9. Davidson IA, Dewey ME, Copeland JRM. The relationship between mortality and mental disorder: evidence from the Liverpool Longitudinal Study. Int J Geriatr Psychiatry 1988; 3: 95-98.
10. Russ TC, Stamatakis E, Hamer M, Starr JM, Kivimaki M, Batty GD. Association between psychological distress and mortality: individual participant pooled analysis of 10 prospective cohort studies. BMJ 2012; 345: e4933.
11. Schulz R, Beach SR, Ives DG, Martire LM, Ariyo AA, Kop WJ. Association between depression and mortality in older adults: The Cardiovascular Health Study. Arch Intern Med 2000; 160: 1761-1768.
12. Rodda J, Walker Z, Carter J. Depression in older adults. BMJ 2011; 343: d5219.
13. Volkert J, Schulz H, Härter M, Wlodarczyk O, Andreas S. The prevalence of mental disorders in older people in Western countries-a meta-analyiss. Ageing Res Rev 2013; 12: 339-353.
14. Cole MG, Dendukuri N. Risk factors for depression among elderly community subjects: A systematic review and meta-analysis. Am J Psychiatry 2003; 160: 1147-1156.
15. Djernes JK. Prevalence and predictors of depression in populations of elderly: A review. Acta Psychiatr Scand 2006; 113: 372-387.
16. Blumberger DM, Daskalakis ZJ, Mulsant BH. Biomarkers in geriatric psychiatry: searching for the holy grail? Curr Opin Psychiatry 2008; 21: 533-539.
17. Blazer DG, Hybels CF. Origins of depression in later life. Psychol Med 2005; 35: 1241-1252.
18. Kalia M, Costa E Silva J. Biomarkers of psychiatric diseases: current status and future prospects. Metabolism 2015; 64 (3, Supplement 1): S11-S15.
19. Le Roith D. Seminars in medicine of the Beth Israel Deaconess Medical Center. Insulin-like growth factors. N Engl J Med 1997; 336: 633-640.
20. Humbel RE. Insulin-like growth factors I and II. Eur J Biochem 1990; 190: 445-462.
21. Junnila RK, List EO, Berryman DE, Murrey JW, Kopchick JJ. The GH/IGF-1 axis in ageing and longevity. Nat Rev Endocrinol 2013; 9: 366-376.
22. Philippou A, Maridaki M, Halapas A, Koutsilieris M. The role of the insulin-like growth factor 1 (IGF-1) in skeletal muscle physiology. In Vivo 2007; 21: 45-54.
23. Wit JM, Walenkamp MJ. Role of insulin-like growth factors in growth, development and feeding. World Rev Nutr Diet 2013; 106: 60-65.
24. Rosen CJ. Insulin-like growth factor I and bone mineral density: experience from animal models and human observational studies. Best Pract Res Clin Endocrinol Metab 2004; 18: 423-435.
25. Chhabra Y, Waters MJ, Brooks AJ. Role of the growth hormone-IGF-1 axis in cancer. Expert Rev Endocrinol Metab 2011; 6: 71-84.
26. Delafontaine P, Song YH, Li Y. Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels. Arterioscler Thromb Vasc Biol 2004; 24: 435-444.
27. Higashi Y, Quevedo HC, Tiwari S, Sukhanov S, Shai SY, Anwar A et al. The interaction between IGF-1, atherosclerosis and vascular aging. Front Horm Res 2014; 43: 107-124.
28. Mitschelen M, Yan H, Farley JA, Warrington JP, Han S, Hereñú CB et al. Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: A potential model of geriatric depression. Neuroscience 2011; 185: 50-60.
29. Duman CH, Schlesinger L, Terwilliger R, Russell DS, Newton SS, Duman RS. Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise. Behav Brain Res 2009; 198: 366-371.
30. Hoshaw BA, Malberg JE, Lucki I. Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects. Brain Res 2005; 1037: 204-208.
31. Bondy CA, Cheng CM. Signaling by insulin-like growth factor 1 in brain. Eur J Pharmacol 2004; 490: 25-31.
32. Szczesny E, Slusarczyk J, Glombik K, Budziszewska B, Kubera M, Lason W et al. Possible contribution of IGF-1 to depressive disorder. Pharmacol Rep 2013; 65: 1622-1631.
33. van Dam PS, Aleman A, de Vries WR, Deijen JB, van der Veen EA, de Haan EHF et al. Growth hormone, insulin-like growth factor I and cognitive function in adults. Growth Horm IGF Res 2000; 10(Suppl B): S69-S73.
34. Schneider HJ, Pagotto U, Stalla GK. Central effects of the somatotropic system. Eur J Endocrinol 2003; 149: 377-392.
35. Jacobs BL, van Praag H, Gage FH. Adult brain neurogenesis and psychiatry: A novel theory of depression. Mol Psychiatry 2000; 5: 262-269.
36. Torres Aleman I. Role of insulin-like growth factors in neuronal plasticity and neuroprotection. Adv Exp Med Biol 2005; 567: 243-258.
37. Sievers C, Auer MK, Klotsche J, Athanasoulia AP, Schneider HJ, Nauck M et al. IGF-I levels and depressive disorders: results from the Study of Health in Pomerania (SHIP). Eur Neuropsychopharmacol 2014; 24: 890-896.
38. van Varsseveld NC, van Bunderen, Sohl E, Comijs HC, Penninx BWJH, Lips P et al. Serum insulin-like growth factor 1 and late-life depression: A populationbased study. Psychoneuroendocrinology 2015; 54: 31-40.
39. NatCen Social Research. English Longitudinal Study of Ageing (ELSA): Wave One to Wave Five-User Guide to the datasets. Available from http://www.ifs.org.uk/elsa/user-guides/waves-1-5-datasets-user-guide.pdf [accessed on 16 February 2015].
40. Freeman Laboratories Newcastle (2012). DPC Immulite 2000-IGF-1. (Laboratory summary of methods used up to 02 February 2012, available from laboratory on request).
41. Radloff LS. The CES-D Scale: A self-report depression scale for research in the general population. Appl Psychol Meas 1977; 1: 385.
42. Steffick DE. Documentation of Affective Functioning Measures in the Health and Retirement Study. HRS. Survey Research Center University of Michigan: Ann Arbor, MI, USA, 2000.
43. Karim J, Weisz R, Bibi Z, ur Rehman S. Validation of the eight-item Center for Epidemiologic Studies Depression Scale (CES-D) among older adults. Curr Psychol 2014; 1-20.
44. Blake H, Mo P, Malik S, Thomas S. How effective are physical activity interventions for alleviating depressive symptoms in older people? A systematic review. Clin Rehab 2009; 23: 873-887.
45. Reinecke MA, Schultz TM. Comparison of self-report and clinician ratings of depression among outpatient adolescents. Depression 1995; 3: 139-145.
46. Turvey CL, Wallace RB, Herzog R. A revised CES-D measure of depressive symptoms and a DSM-based measure of major depressive episodes in the elderly. Int Psychogeriatr 1999; 11: 139-148.
47. UK Data Archive Study Number 5050-English Longitudinal Study of Ageing (2009). English Longitudinal Study of Ageing Wave Four Interview Questionnaire -2008-2009 Draft Version 1.0. Available from http://www.elsa-project.ac.uk/uploads/elsa/docs-w4/questionnaire-main.pdf [accessed on 3 May 2015].
48. Sanchez-Villegas A, Schlatter J, Ortuno F, Lahortiga F, Pla J, Benito S et al. Validity of a self-reported diagnosis of depression among participants in a cohort study using the Structured Clinical Interview for DSM-IV (SCID-I). BMC Psychiatry 2008; 8: 43.
49. Banks J, Breeze E, Crawford R, Demakakos P, de Oliveira C, Gjonça E et al. Financial Circumstances, Health and Well-Being of the Older Population in England: The 2008 English Longitudinal Study of Ageing (wave 4). Institute of Fiscal Studies: London, UK, 2010.
50. Goodman-Gruen D, Barrett-Connor E. Epidemiology of insulin-like growth factor-I in elderly men and women: The Rancho Bernardo Study. Am J Epidemiol 1997; 145: 970-976.
51. StataCorp LP. Stata 12 . StataCorp: College Station, TX, USA, 2011.
52. Sievers C, Dimopoulou C, Pfister H, Lieb R, Steffin B, Roemmler J et al. Prevalence of mental disorders in acromegaly: A cross-sectional study in 81 acromegalic patients. Clin Endocrinol (Oxf) 2009; 71: 691-701.
53. McGauley GA, Cuneo RC, Salomon F, Sonksen PH. Psychological well-being before and after growth hormone treatment in adults with growth hormone deficiency. Horm Res 1990; 33(Suppl 4): 52-54.
54. Wexler T, Gunnell L, Omer Z, Kuhlthau K, Beauregard C, Graham G et al. Hormone deficiency is associated with decreased quality of life in patients with prior acromegaly. J Clin Endocrinol Metab 2009; 94: 2471-2477.
55. Deuschle M, Blum WF, Strasburger CJ, Schweiger U, Weber B, Korner A et al. Insulin-like growth factor-I (IGF-I) plasma concentrations are increased in depressed patients. Psychoneuroendocrinology 1997; 22: 493-503.
56. Franz B, Buysse DJ, Cherry CR, Gray NS, Grochocinski VJ, Frank E et al. Insulin-like growth factor 1 and growth hormone binding protein in depression: A preliminary communication. J Psychiatr Res 1999; 33: 121-127.