메뉴 건너뛰기




Volumn 69, Issue , 2017, Pages 43-50

Increased intestinal permeability, measured by serum zonulin, is associated with metabolic risk markers in overweight pregnant women

Author keywords

Intestinal permeability; Low grade inflammation; Metabolic endotoxemia; Overweight; Pregnancy

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; GLYCOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HIGH SENSITIVE C REACTIVE PROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ZONULIN; BIOLOGICAL MARKER; CHOLERA TOXIN;

EID: 85011886993     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2016.12.015     Document Type: Article
Times cited : (53)

References (50)
  • 1
    • 84930754244 scopus 로고    scopus 로고
    • Inflammation in maternal obesity and gestational diabetes mellitus
    • [1] Pantham, P., Aye, I.L., Powell, T.L., Inflammation in maternal obesity and gestational diabetes mellitus. Placenta 36 (2015), 709–715.
    • (2015) Placenta , vol.36 , pp. 709-715
    • Pantham, P.1    Aye, I.L.2    Powell, T.L.3
  • 2
    • 35848961430 scopus 로고    scopus 로고
    • Metabolic changes in pregnancy
    • [2] Lain, K.Y., Catalano, P.M., Metabolic changes in pregnancy. Clin Obstet Gynecol 50 (2007), 938–948.
    • (2007) Clin Obstet Gynecol , vol.50 , pp. 938-948
    • Lain, K.Y.1    Catalano, P.M.2
  • 3
    • 84949109744 scopus 로고    scopus 로고
    • The effect of maternal inflammation on foetal programming of metabolic disease
    • [3] Ingvorsen, C., Brix, S., Ozanne, S.E., Hellgren, L.I., The effect of maternal inflammation on foetal programming of metabolic disease. Acta Physiol (Oxf) 214 (2015), 440–449.
    • (2015) Acta Physiol (Oxf) , vol.214 , pp. 440-449
    • Ingvorsen, C.1    Brix, S.2    Ozanne, S.E.3    Hellgren, L.I.4
  • 4
  • 5
    • 82955170624 scopus 로고    scopus 로고
    • Dietary factors and low-grade inflammation in relation to overweight and obesity
    • [5] Calder, P.C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., et al. Dietary factors and low-grade inflammation in relation to overweight and obesity. Br J Nutr 106:Suppl. 3 (2011), S5–78.
    • (2011) Br J Nutr , vol.106 , pp. S5-78
    • Calder, P.C.1    Ahluwalia, N.2    Brouns, F.3    Buetler, T.4    Clement, K.5    Cunningham, K.6
  • 6
    • 27744463859 scopus 로고    scopus 로고
    • Central obesity as a major determinant of increased high-sensitivity C-reactive protein in metabolic syndrome
    • [6] Santos, A.C., Lopes, C., Guimarães, J.T., Barros, H., Central obesity as a major determinant of increased high-sensitivity C-reactive protein in metabolic syndrome. Int J Obes (Lond) 29 (2005), 1452–1456.
    • (2005) Int J Obes (Lond) , vol.29 , pp. 1452-1456
    • Santos, A.C.1    Lopes, C.2    Guimarães, J.T.3    Barros, H.4
  • 7
    • 84872023970 scopus 로고    scopus 로고
    • Inflammatory markers and risk of type 2 diabetes: a systematic review and meta-analysis
    • [7] Wang, X., Bao, W., Liu, J., Ouyang, Y.Y., Wang, D., Rong, S., et al. Inflammatory markers and risk of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care 36 (2013), 166–175.
    • (2013) Diabetes Care , vol.36 , pp. 166-175
    • Wang, X.1    Bao, W.2    Liu, J.3    Ouyang, Y.Y.4    Wang, D.5    Rong, S.6
  • 8
    • 33645277645 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein as cardiovascular risk marker in patients with diabetes mellitus
    • [8] Pfützner, A., Forst, T., High-sensitivity C-reactive protein as cardiovascular risk marker in patients with diabetes mellitus. Diabetes Technol Ther 8 (2006), 28–36.
    • (2006) Diabetes Technol Ther , vol.8 , pp. 28-36
    • Pfützner, A.1    Forst, T.2
  • 9
    • 84855983052 scopus 로고    scopus 로고
    • C-reactive protein and hormones but not IL-6 are associated to body mass index in first trimester of pregnancy
    • [9] Kac, G., Vaz, J.S., Schlüssel, M.M., Moura, A.S., C-reactive protein and hormones but not IL-6 are associated to body mass index in first trimester of pregnancy. Arch Gynecol Obstet 284 (2011), 567–573.
    • (2011) Arch Gynecol Obstet , vol.284 , pp. 567-573
    • Kac, G.1    Vaz, J.S.2    Schlüssel, M.M.3    Moura, A.S.4
  • 10
    • 84908375945 scopus 로고    scopus 로고
    • Longitudinal changes in serum proinflammatory markers across pregnancy and postpartum: effects of maternal body mass index
    • [10] Christian, L.M., Porter, K., Longitudinal changes in serum proinflammatory markers across pregnancy and postpartum: effects of maternal body mass index. Cytokine 70 (2014), 134–140.
    • (2014) Cytokine , vol.70 , pp. 134-140
    • Christian, L.M.1    Porter, K.2
  • 12
    • 84881433896 scopus 로고    scopus 로고
    • Gut microbiota, microinflammation, metabolic profile, and zonulin concentration in obese and normal weight subjects
    • 674106 [Epub 2013 Jul 18]
    • [12] Zak-Gołąb, A., Kocełak, P., Aptekorz, M., Zientara, M., Juszczyk, L., Martirosian, G., et al. Gut microbiota, microinflammation, metabolic profile, and zonulin concentration in obese and normal weight subjects. Int J Endocrinol, 674106, 2013, 10.1155/2013/674106 [Epub 2013 Jul 18].
    • (2013) Int J Endocrinol
    • Zak-Gołąb, A.1    Kocełak, P.2    Aptekorz, M.3    Zientara, M.4    Juszczyk, L.5    Martirosian, G.6
  • 13
    • 84862067310 scopus 로고    scopus 로고
    • Circulating zonulin, a marker of intestinal permeability, is increased in association with obesity-associated insulin resistance
    • [Epub 2012 May 18]
    • [13] Moreno-Navarrete, J.M., Sabater, M., Ortega, R.W., Fernández-Real, J.M., Circulating zonulin, a marker of intestinal permeability, is increased in association with obesity-associated insulin resistance. PLoS One, 7, 2012, e37160, 10.1371/journal.pone.0037160 [Epub 2012 May 18].
    • (2012) PLoS One , vol.7 , pp. e37160
    • Moreno-Navarrete, J.M.1    Sabater, M.2    Ortega, R.W.3    Fernández-Real, J.M.4
  • 14
    • 84920618880 scopus 로고    scopus 로고
    • Circulating zonulin levels in newly diagnosed Chinese type 2 diabetes patients
    • [14] Zhang, D., Zhang, L., Zheng, Y., Yue, F., Russell, R.D., Zeng, Y., Circulating zonulin levels in newly diagnosed Chinese type 2 diabetes patients. Diabetes Res Clin Pract 106 (2014), 312–318.
    • (2014) Diabetes Res Clin Pract , vol.106 , pp. 312-318
    • Zhang, D.1    Zhang, L.2    Zheng, Y.3    Yue, F.4    Russell, R.D.5    Zeng, Y.6
  • 15
    • 84893839605 scopus 로고    scopus 로고
    • Increased circulatory levels of lipopolysaccharide (LPS) and zonulin signify novel biomarkers of proinflammation in patients with type 2 diabetes
    • [15] Jayashree, B., Bibin, Y.S., Prabhu, D., Shanthirani, C.S., Gokulakrishnan, K., Lakshmi, B.S., et al. Increased circulatory levels of lipopolysaccharide (LPS) and zonulin signify novel biomarkers of proinflammation in patients with type 2 diabetes. Mol Cell Biochem 388 (2014), 203–210.
    • (2014) Mol Cell Biochem , vol.388 , pp. 203-210
    • Jayashree, B.1    Bibin, Y.S.2    Prabhu, D.3    Shanthirani, C.S.4    Gokulakrishnan, K.5    Lakshmi, B.S.6
  • 16
    • 84871860548 scopus 로고    scopus 로고
    • Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia
    • [16] Moreira, A.P., Texeira, T.F., Ferreira, A.B., Peluzio Mdo, C., Alfenas, R.C., Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia. Br J Nutr 108 (2012), 801–809.
    • (2012) Br J Nutr , vol.108 , pp. 801-809
    • Moreira, A.P.1    Texeira, T.F.2    Ferreira, A.B.3    Peluzio Mdo, C.4    Alfenas, R.C.5
  • 17
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • [17] Cani, P.D., Bibiloni, R., Knauf, C., Waget, A., Neyrinck, A.M., Delzenne, N.M., et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57 (2008), 1470–1481.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6
  • 20
    • 33745311630 scopus 로고    scopus 로고
    • Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives
    • [20] Sapone, A., de Magistris, L., Pietzak, M., Clemente, M.G., Tripathi, A., Cucca, F., et al. Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives. Diabetes 55 (2006), 1443–1449.
    • (2006) Diabetes , vol.55 , pp. 1443-1449
    • Sapone, A.1    de Magistris, L.2    Pietzak, M.3    Clemente, M.G.4    Tripathi, A.5    Cucca, F.6
  • 21
    • 84917736907 scopus 로고    scopus 로고
    • Increased circulating zonulin in children with biopsy-proven nonalcoholic fatty liver disease
    • [21] Pacifico, L., Bonci, E., Marandola, L., Romaggioli, S., Bascetta, S., Chiesa, C., Increased circulating zonulin in children with biopsy-proven nonalcoholic fatty liver disease. World J Gastroenterol 20 (2014), 17107–17114.
    • (2014) World J Gastroenterol , vol.20 , pp. 17107-17114
    • Pacifico, L.1    Bonci, E.2    Marandola, L.3    Romaggioli, S.4    Bascetta, S.5    Chiesa, C.6
  • 22
    • 84920449788 scopus 로고    scopus 로고
    • Serum zonulin is elevated in women with polycystic ovary syndrome and correlates with insulin resistance and severity of anovulation
    • [22] Zhang, D., Zhang, L., Yue, F., Zheng, Y., Russell, R., Serum zonulin is elevated in women with polycystic ovary syndrome and correlates with insulin resistance and severity of anovulation. Eur J Endocrinol 172 (2015), 29–36.
    • (2015) Eur J Endocrinol , vol.172 , pp. 29-36
    • Zhang, D.1    Zhang, L.2    Yue, F.3    Zheng, Y.4    Russell, R.5
  • 23
    • 84871951482 scopus 로고    scopus 로고
    • The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind randomized clinical trial
    • [23] Liu, Z.H., Huang, M.J., Zhang, X.W., Wang, L., Huang, N.Q., Peng, H., et al. The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind randomized clinical trial. Am J Clin Nutr 97 (2013), 117–126.
    • (2013) Am J Clin Nutr , vol.97 , pp. 117-126
    • Liu, Z.H.1    Huang, M.J.2    Zhang, X.W.3    Wang, L.4    Huang, N.Q.5    Peng, H.6
  • 24
    • 84902543550 scopus 로고    scopus 로고
    • Endocrinology & metabolism. Diabetes trial unit. HOMA calculator
    • Available from: [Accessed April 2016]
    • [24] The Oxford Centre for Diabetes, Endocrinology & metabolism. Diabetes trial unit. HOMA calculator. Available from: http://www.dtu.ox.ac.uk/ [Accessed April 2016].
    • The Oxford Centre for Diabetes1
  • 25
    • 0034456568 scopus 로고    scopus 로고
    • Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans
    • [25] Katz, A., Nambi, S.S., Mather, K., Baron, A.D., Follmann, D.A., Sullivan, G., et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 85 (2000), 2402–2410.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2402-2410
    • Katz, A.1    Nambi, S.S.2    Mather, K.3    Baron, A.D.4    Follmann, D.A.5    Sullivan, G.6
  • 26
    • 84924533418 scopus 로고    scopus 로고
    • Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics
    • [26] Soininen, P., Kangas, A.J., Würtz, P., Suna, T., Ala-Korpela, M., Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics. Circ Cardiovasc Genet 8 (2015), 192–206.
    • (2015) Circ Cardiovasc Genet , vol.8 , pp. 192-206
    • Soininen, P.1    Kangas, A.J.2    Würtz, P.3    Suna, T.4    Ala-Korpela, M.5
  • 27
    • 79952006811 scopus 로고    scopus 로고
    • Pregravid obesity associates with increased maternal endotoxemia and metabolic inflammation
    • [Epub 2010 Oct 7]
    • [27] Basu, S., Haghiac, M., Surace, P., Challier, J.C., Guerre-Millo, M., Singh, K., et al. Pregravid obesity associates with increased maternal endotoxemia and metabolic inflammation. Obesity (Silver Spring) 19 (2011), 476–482, 10.1038/oby.2010.215 [Epub 2010 Oct 7].
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 476-482
    • Basu, S.1    Haghiac, M.2    Surace, P.3    Challier, J.C.4    Guerre-Millo, M.5    Singh, K.6
  • 28
    • 0037469232 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention; American Heart Association. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association
    • [28] Pearson, T.A., Mensah, G.A., Alexander, R.W., Anderson, J.L., Cannon, R.O. III, Criqui, M., et al. Centers for Disease Control and Prevention; American Heart Association. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 107 (2003), 499–511.
    • (2003) Circulation , vol.107 , pp. 499-511
    • Pearson, T.A.1    Mensah, G.A.2    Alexander, R.W.3    Anderson, J.L.4    Cannon, R.O.5    Criqui, M.6
  • 29
    • 17544390219 scopus 로고    scopus 로고
    • Cardiology patient page. C-reactive protein: a simple test to help predict risk of heart attack and stroke
    • [29] Ridker, P.M., Cardiology patient page. C-reactive protein: a simple test to help predict risk of heart attack and stroke. Circulation 108 (2003), e81–e85.
    • (2003) Circulation , vol.108 , pp. e81-e85
    • Ridker, P.M.1
  • 30
    • 84899140315 scopus 로고    scopus 로고
    • Inflammasomes and metabolic disorders: old genes in modern diseases
    • [30] Robbins, G.R., Wen, H., Ting, J.P., Inflammasomes and metabolic disorders: old genes in modern diseases. Mol Cell 54 (2014), 297–308.
    • (2014) Mol Cell , vol.54 , pp. 297-308
    • Robbins, G.R.1    Wen, H.2    Ting, J.P.3
  • 31
    • 0029936532 scopus 로고    scopus 로고
    • Longitudinal study on lipoprotein profile, high density lipoprotein subclass, and postheparin lipases during gestation in women
    • [31] Alvarez, J.J., Montelongo, A., Iglesias, A., Lasunción, M.A., Herrera, E., Longitudinal study on lipoprotein profile, high density lipoprotein subclass, and postheparin lipases during gestation in women. J Lipid Res 37 (1996), 299–308.
    • (1996) J Lipid Res , vol.37 , pp. 299-308
    • Alvarez, J.J.1    Montelongo, A.2    Iglesias, A.3    Lasunción, M.A.4    Herrera, E.5
  • 33
    • 84959505464 scopus 로고    scopus 로고
    • Gut microbiota-derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity
    • [33] Hersoug, L.G., Møller, P., Loft, S., Gut microbiota-derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity. Obes Rev 17 (2016), 297–312.
    • (2016) Obes Rev , vol.17 , pp. 297-312
    • Hersoug, L.G.1    Møller, P.2    Loft, S.3
  • 35
    • 84942739500 scopus 로고    scopus 로고
    • Prediction of gestational diabetes mellitus in the first trimester: comparison of C-reactive protein, fasting plasma glucose, insulin and insulin sensitivity indices
    • [35] Ozgu-Erdinc, A.S., Yilmaz, S., Yeral, M.I., Seckin, K.D., Erkaya, S., Danisman, A.N., Prediction of gestational diabetes mellitus in the first trimester: comparison of C-reactive protein, fasting plasma glucose, insulin and insulin sensitivity indices. J Matern Fetal Neonatal Med 28 (2015), 1957–1962.
    • (2015) J Matern Fetal Neonatal Med , vol.28 , pp. 1957-1962
    • Ozgu-Erdinc, A.S.1    Yilmaz, S.2    Yeral, M.I.3    Seckin, K.D.4    Erkaya, S.5    Danisman, A.N.6
  • 36
    • 84899514136 scopus 로고    scopus 로고
    • Comparative study between different biomarkers for early prediction of gestational diabetes mellitus
    • [36] Maged, A.M., Moety, G.A., Mostafa, W.A., Hamed, D.A., Comparative study between different biomarkers for early prediction of gestational diabetes mellitus. J Matern Fetal Neonatal Med 27 (2014), 1108–1112.
    • (2014) J Matern Fetal Neonatal Med , vol.27 , pp. 1108-1112
    • Maged, A.M.1    Moety, G.A.2    Mostafa, W.A.3    Hamed, D.A.4
  • 37
    • 84858604478 scopus 로고    scopus 로고
    • Arterial stiffness, inflammatory and pro-atherogenic markers in gestational diabetes mellitus
    • [37] Salmi, A.A., Zaki, N.M., Zakaria, R., Nor Aliza, A.G., Rasool, A.H., Arterial stiffness, inflammatory and pro-atherogenic markers in gestational diabetes mellitus. Vasa 41:2 (2012), 96–104.
    • (2012) Vasa , vol.41 , Issue.2 , pp. 96-104
    • Salmi, A.A.1    Zaki, N.M.2    Zakaria, R.3    Nor Aliza, A.G.4    Rasool, A.H.5
  • 38
  • 39
    • 84901853330 scopus 로고    scopus 로고
    • Total adiponectin, but not inflammatory markers C-reactive protein, tumor necrosis factor-α, interluekin-6 and monocyte chemoattractant protein-1, correlates with increasing glucose intolerance in pregnant Chinese-Americans
    • [39] Kim, S.Y., Sy, V., Araki, T., Babushkin, N., Huang, D., Tan, D., et al. Total adiponectin, but not inflammatory markers C-reactive protein, tumor necrosis factor-α, interluekin-6 and monocyte chemoattractant protein-1, correlates with increasing glucose intolerance in pregnant Chinese-Americans. J Diabetes 6 (2014), 360–368.
    • (2014) J Diabetes , vol.6 , pp. 360-368
    • Kim, S.Y.1    Sy, V.2    Araki, T.3    Babushkin, N.4    Huang, D.5    Tan, D.6
  • 40
    • 84958156886 scopus 로고    scopus 로고
    • First trimester screening for gestational diabetes mellitus by maternal factors and markers of inflammation
    • [40] Syngelaki, A., Visser, G.H., Krithinakis, K., Wright, A., Nicolaides, K.H., First trimester screening for gestational diabetes mellitus by maternal factors and markers of inflammation. Metabolism 65 (2016), 131–137.
    • (2016) Metabolism , vol.65 , pp. 131-137
    • Syngelaki, A.1    Visser, G.H.2    Krithinakis, K.3    Wright, A.4    Nicolaides, K.H.5
  • 42
    • 84951175436 scopus 로고    scopus 로고
    • The biomarker GlycA is associated with chronic inflammation and predicts long-term risk of severe infection
    • [42] Ritchie, S.C., Würtz, P., Nath, A.P., Abraham, G., Havulinna, A.S., Fearnley, L.G., et al. The biomarker GlycA is associated with chronic inflammation and predicts long-term risk of severe infection. Cell Syst 1 (2015), 293–301.
    • (2015) Cell Syst , vol.1 , pp. 293-301
    • Ritchie, S.C.1    Würtz, P.2    Nath, A.P.3    Abraham, G.4    Havulinna, A.S.5    Fearnley, L.G.6
  • 43
    • 84939958074 scopus 로고    scopus 로고
    • Novel protein glycan derived biomarker is associated with incident diabetes
    • [43] Akinkuolie, A.O., Pradhan, A.D., Ridker, P.M., Mora, S., Novel protein glycan derived biomarker is associated with incident diabetes. Circulation, 2013, A18807.
    • (2013) Circulation , pp. A18807
    • Akinkuolie, A.O.1    Pradhan, A.D.2    Ridker, P.M.3    Mora, S.4
  • 44
    • 84923074997 scopus 로고    scopus 로고
    • A novel protein glycan biomarker and future cardiovascular disease events
    • [44] Akinkuolie, A.O., Buring, J.E., Ridker, P.M., Mora, S., A novel protein glycan biomarker and future cardiovascular disease events. J Am Heart Assoc, 3, 2014, e001221, 10.1161/JAHA.114.001221.
    • (2014) J Am Heart Assoc , vol.3 , pp. e001221
    • Akinkuolie, A.O.1    Buring, J.E.2    Ridker, P.M.3    Mora, S.4
  • 45
    • 84946607215 scopus 로고    scopus 로고
    • GlycA, a marker of acute phase glycoproteins, and the risk of incident type 2 diabetes mellitus: PREVEND study
    • [45] Connelly, M.A., Gruppen, E.G., Wolak-Dinsmore, J., Matyus, S.P., Riphagen, I.J., Shalaurova, I., et al. GlycA, a marker of acute phase glycoproteins, and the risk of incident type 2 diabetes mellitus: PREVEND study. Clin Chim Acta 452 (2016), 10–17.
    • (2016) Clin Chim Acta , vol.452 , pp. 10-17
    • Connelly, M.A.1    Gruppen, E.G.2    Wolak-Dinsmore, J.3    Matyus, S.P.4    Riphagen, I.J.5    Shalaurova, I.6
  • 46
    • 53849107145 scopus 로고    scopus 로고
    • Reference values for alpha1-acid glycoprotein, alpha1-antitrypsin, albumin, haptoglobin, C-reactive protein, IgA, IgG and IgM during pregnancy
    • [46] Larsson, A., Palm, M., Hansson, L.O., Basu, S., Axelsson, O., Reference values for alpha1-acid glycoprotein, alpha1-antitrypsin, albumin, haptoglobin, C-reactive protein, IgA, IgG and IgM during pregnancy. Acta Obstet Gynecol Scand 87 (2008), 1084–1088.
    • (2008) Acta Obstet Gynecol Scand , vol.87 , pp. 1084-1088
    • Larsson, A.1    Palm, M.2    Hansson, L.O.3    Basu, S.4    Axelsson, O.5
  • 48
    • 0019430699 scopus 로고
    • Plasma alpha 1-acid glycoprotein levels in pregnancy
    • [48] Chu, C.Y., Singla, V.P., Wang, H.P., Sweet, B., Lai, L.T., Plasma alpha 1-acid glycoprotein levels in pregnancy. Clin Chim Acta 112 (1981), 235–240.
    • (1981) Clin Chim Acta , vol.112 , pp. 235-240
    • Chu, C.Y.1    Singla, V.P.2    Wang, H.P.3    Sweet, B.4    Lai, L.T.5
  • 49
    • 0025000483 scopus 로고
    • Quantitative analysis of serum alpha 1-acid glycoprotein levels in normal and diabetic pregnancy
    • [49] Honda, M., Omori, Y., Minei, S., Oshiyama, T., Shimizu, M., Sanaka, M., et al. Quantitative analysis of serum alpha 1-acid glycoprotein levels in normal and diabetic pregnancy. Diabetes Res Clin Pract 10 (1990), 147–152.
    • (1990) Diabetes Res Clin Pract , vol.10 , pp. 147-152
    • Honda, M.1    Omori, Y.2    Minei, S.3    Oshiyama, T.4    Shimizu, M.5    Sanaka, M.6
  • 50
    • 67349122300 scopus 로고    scopus 로고
    • Serum trypsin inhibitory capacity in normal pregnancy and gestational diabetes mellitus
    • [Epub 2009 Apr 2]
    • [50] Yaghmaei, M., Hashemi, M., Shikhzadeh, A., Mokhtari, M., Niazi, A., Ghavami, S., Serum trypsin inhibitory capacity in normal pregnancy and gestational diabetes mellitus. Diabetes Res Clin Pract 84:3 (2009), 201–204, 10.1016/j.diabres.2009.03.003 [Epub 2009 Apr 2].
    • (2009) Diabetes Res Clin Pract , vol.84 , Issue.3 , pp. 201-204
    • Yaghmaei, M.1    Hashemi, M.2    Shikhzadeh, A.3    Mokhtari, M.4    Niazi, A.5    Ghavami, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.