Serial sampling of high-sensitivity cardiac troponin T may not be required for prediction of acute myocardial infarction diagnosis in chest pain patients with highly abnormal concentrations at presentation

Clinical Chemistry

Volumn 63, Issue 2, 2017, Pages 542-551

  Mueller Hennessen, Matthias ^a   Mueller, Christian ^b   Giannitsis, Evangelos ^a   Biener, Moritz ^a   Vafaie, Mehrshad ^a   DeFilippi, Christopher R ^c   Christ, Michael ^d   Ordóñez Llanos, Jorge ^e   Panteghini, Mauro ^f   Plebani, Mario ^g   Verschuren, Franck ^h   Melki, Dina ⁱ   French, John K ^j   Christenson, Robert H ^c   Body, Richard ^k   McCord, James ^l   Dinkel, Carina ^m   Katus, Hugo A ^a   Lindahl, Bertil ⁿ  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d Paracelsus Medical University   (Germany)

^e BIOMEDICAL RESEARCH INSTITUTE SANT PAU IIB SANT PAU   (Spain)

^f UNIVERSITY OF MILAN   (Italy)

^g UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^h CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

ⁱ KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^j UNIVERSITY OF NEW SOUTH WALES   (Australia)

^k MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^l HENRY FORD HEART AND VASCULAR INSTITUTE   (United States)

^m ROCHE DIAGNOSTICS GMBH   (Germany)

ⁿ UPPSALA UNIVERSITY   (Sweden)

more..

Author keywords

[No Author keywords available]

Indexed keywords

TROPONIN T;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; BLOOD SAMPLING; CARDIAC TROPONIN 1 CLIA; CARDIAC TROPONIN 1 CLIA KIT; CARDIOLOGIST; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CORONARY STENT; DIAGNOSTIC TEST ACCURACY STUDY; EMERGENCY WARD; FEMALE; HEART MUSCLE REVASCULARIZATION; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTICENTER STUDY; MYOCARDITIS; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PERCUTANEOUS CORONARY INTERVENTION; PREDICTIVE VALUE; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; TAKOTSUBO CARDIOMYOPATHY; THORAX PAIN; TIME; UNSTABLE ANGINA PECTORIS; ACUTE DISEASE; BLOOD; CHEST PAIN; MYOCARDIAL INFARCTION; VERY ELDERLY;

ACUTE DISEASE; AGED; AGED, 80 AND OVER; CHEST PAIN; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PREDICTIVE VALUE OF TESTS; TROPONIN T;

EID: 85011601722     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2016.258392     Document Type: Article

References (24)

1. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD, et al. Third universal definition of myocardial infarction. Eur Heart J 2012;33:2551-67.
2. MehtaSR, GrangerCB, BodenWE, StegPG, BassandJP, Faxon DP, et al. Early versus delayed invasive intervention in acute coronary syndromes. N Engl J Med 2009;360:2165-75.
3. Keller T, Zeller T, Ojeda F, Tzikas S, Lillpopp L, Sinning C, et al. Serial changes in highly sensitive troponin I assay and early diagnosis of myocardial infarction. JAMA 2011;306:2684-93.
4. ThygesenK, MairJ, GiannitsisE, MuellerC, LindahlB, Blankenberg S, et al. How to use high-sensitivity cardiac troponins in acute cardiac care. Eur Heart J 2012;33:2252-7.
5. Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2016;37:267-315.
6. Mueller C, Giannitsis E, Christ M, Ordonez-Llanos J, de- Filippi C, McCord J, et al. Multicenter evaluation of a 0-hour/1-hour algorithm in the diagnosis of myocardial infarction with high-sensitivity cardiac troponin T. Ann Emerg Med 2016;68:76-87.
7. Giannitsis E, BeckerM, Kurz K, Hess G, ZdunekD, Katus HA. High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission. Clin Chem 2010; 56:642-50.
8. Reichlin T, Hochholzer W, Bassetti S, Steuer S, Stelzig C, Hartwiger S, et al. Early diagnosis of myocardial infarction with sensitive cardiac troponin assays.N Engl J Med 2009; 361:858-67.
9. Keller T, Zeller T, Peetz D, Tzikas S, Roth A, Czyz E, et al. Sensitive troponin I assay in early diagnosis of acute myocardial infarction. N Engl J Med 2009;361:868-77.
10. Mueller M, Biener M, Vafaie M, Doerr S, Keller T, Blankenberg S, et al. Absolute and relative kinetic changes of highsensitivity cardiac troponin T in acute coronary syndrome and in patients with increased troponin in the absence of acute coronary syndrome. Clin Chem 2012;58:209-18.
11. DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1988;44:837-45.
12. Pencina MJ, D'Agostino RB Sr., D'Agostino RB Jr., Vasan RS. Evaluating the added predictive ability of a new marker:fromareaundertheROCcurvetoreclassificationand beyond. StatMed2008;27:157-72; discussion 207-12.
13. Omland T, de Lemos JA, Sabatine MS, Christophi CA, Rice MM, Jablonski KA, et al. A sensitive cardiac troponin T assay in stable coronary artery disease. N Engl J Med 2009;361:2538-47.
14. Lankeit M, Friesen D, Aschoff J, Dellas C, Hasenfuss G, Katus H, et al. Highly sensitive troponin T assay in normotensive patients with acute pulmonary embolism. Eur Heart J 2010;31:1836-44.
15. Reichlin T, Irfan A, Twerenbold R, Reiter M, Hochholzer W, Burkhalter H, et al. Utility of absolute and relative changes in cardiac troponin concentrations in the early diagnosis of acute myocardial infarction. Circulation 2011;124:136-45.
16. Hamm CW, Goldmann BU, Heeschen C, Kreymann G, Berger J, Meinertz T. Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med 1997;337:1648-53.
17. Reichlin T, Schindler C, Drexler B, Twerenbold R, Reiter M, Zellweger C, et al. One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T. Arch Intern Med 2012;172:1211-8.
18. Reichlin T, Twerenbold R, Wildi K, Gimenez MR, Bergsma N, Haaf P, et al. Prospective validation of a 1-hour algorithm to rule-out and rule-in acute myocardial infarction using a high-sensitivity cardiac troponin T assay. CMAJ 2015;187:E243-52.
19. Normann J, Mueller M, Biener M, Vafaie M, Katus HA, Giannitsis E. Effect of older age on diagnostic and prognostic performance of high-sensitivity troponin T in patients presenting to an emergency department. Am Heart J 2012;164:698-705.e4.
20. Hammarsten O, Fu ML, Sigurjonsdottir R, Petzold M, Said L, Landin-Wilhelmsen K, et al. Troponin T percentiles from a random population sample, emergency room patients and patients with myocardial infarction. Clin Chem 2012;58:628-37.
21. Mueller M, Biener M, Vafaie M, Blankenberg S, White HD, Katus HA, et al. Prognostic performance of kinetic changes of high-sensitivity troponin T in acute coronary syndrome and in patients with increased troponin without acute coronary syndrome. Int J Cardiol 2014;174:524-9.
22. Kavsak PA, Ko DT, Wang X, Macrae AR, Jaffe AS. Increasing cardiac troponin changes measured by a research high-sensitivity troponin I assay: absolute vs percentage changes and long-term outcomes in a chest pain cohort. Clin Chem 2010;56:1902-4.
23. Apple FS. A new season for cardiac troponin assays: it's time to keep a scorecard. Clin Chem 2009;55:1303-6.
24. Apple FS, Collinson PO. Analytical characteristics of high-sensitivity cardiac troponin assays. Clin Chem 2012;58:54-61.