Redistribution of Gq/11α in the pituitary gonadotrope in response to a gonadotropin-releasing hormone agonist

Endocrinology

Volumn 139, Issue 1, 1998, Pages 397-402

  Cornea, Anda ^a   Janovick, Jo Ann ^a   Stanislaus, Dinesh ^a,b   Conn, P Michael ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85011454583     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/endo.139.1.5687     Document Type: Article

References (27)

1. ConnPM, JanovickJA, StanislausD, KuphalD, Jennes L1995 Molecular and cellular basis of gonadotropin releasing hormone action in the pituitary and central nervous system. Vitam Horm50:151-214
2. ProbstWC, SnyderLA, SchusterDI, BrosiusJ, SealfonSC1992Sequence alignment of the G-protein coupled receptor superfamily. DNA Cell Biol11:1-20
3. HawesBE, ConnPM1992Sodium fluoride provokes gonadotrope desensitization to GnRH and gonadotrope sensitization to A23187: evidence for multiple G proteins in GnRH action. Endocrinology130:2465-2475
4. HawesBE, BarnesS, ConnPM1993Cholera toxin and pertussis toxin provoke differential effects on luteinizing hormone release, inositol phosphate production, and gonadotropin-releasing hormone (GnRH) receptor binding in the gonadotrope: evidence for multiple guanyl nucleotide binding proteins in GnRH action. Endocrinology132:2124-2130
5. StanislausD, JanovickJA, BrothersS, ConnPM1997Regulation of Gq/11a-by the gonadotropin-releasing hormone receptor. Mol Endocrinol6:738-746
6. Stanislaus D, Janovick JA, Wilkie T, Ji TH, Conn PM, Gn knockout mice show altered response to GnRH agonist: evidence for a role of G1, in pituitary regulation. Program of the 79th Annual Meeting of The Endocrine Society, June 1997, Minneapolis, MN Pl-136:168 (Abstract)
7. LuttrellLM, OstrowskiJ, CotecchiaS, KendallH, LefkowitzRJ1993Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors. Science259:1453-1457
8. ConnPM, ChafouleasJ, RogersD, MeansAR1981Gonadotropin releasing hormone stimulates calmodulin redistribution in rat pituitary. Nature 292:264-265
9. McArdle CA, Conn PM 1986 Hormone-stimulated redistribution of gonado-trope protein kinase C in vivo: dependence on Ca2+ influx. Mol Pharmacol29:570-576
10. ConnPM, RogersDC, StewartJM, NeidelJ, SheffieldT1982Conversion of a gonadotropin releasing hormone antagonist to an agonist. Nature296:653-655
11. JanovickJA, ConnPM1996Gonadotropin releasing hormone agonist provokes homologous receptor microaggregation: an early event in seven-trans-membrane receptor mediated signaling. Endocrinology137:3602-3605
12. HazumE, CuatrecasasP, MarianJ, ConnPM1980Receptor-mediated internalization of fluorescent gonadotropin-releasing hormone by pituitary gona-dotropes. Proc Natl Acad Sci USA77:6692-6695
13. NaorZ, AtlasD, ClaytonRN, FormanDS, AmsterdamA, CattKJ1981Interaction of fluorescent gonadotropin-releasing hormone with receptors in cultured pituitary cells.J Biol Chem256:3049-3052
14. MarianJ, ConnPM1979Gonadotropin releasing hormone stimulation of cultured pituitary cells requires calcium. Mol Pharmacol16:196-201
15. ConnPM, JanovickJA, BradenTD, MaurerRA, JennesL1992Slip: a unique secretogranin/chromogranin of the pituitary released in response to gonado-tropin-releasing hormone. Endocrinology130:3033-3040
16. TuckerLM, MortonAJ1995A simple method for quantifying changes in neuronal populations in primary cultures of dissociated rat brain. J Neurosci Methods59:217-223
17. SavioT, LeviG1993Neurotoxicity of HIV coat protein gp120, NMDA receptors, and protein kinase C: a study with rat cerebellar granule cell cultures. J Neurosci Res34:265-272
18. HunterWM, GreenwoodFC1962Preparation of iodine-131 labeled growth hormone of high specific activity. Nature194:495-496
19. SmithWA, CooperRL, ConnPM1982Altered pituitary responsiveness to gonadotropin-releasing hormone in middle-aged rats with 4-day estrous cycles. Endocrinology111:1843-1848
20. GuptaR, MortonDL1979Double-antibody method and the protein-A-bear-ing Staphylococcus aureus cells method compared for separating bound and free antigen in radioimmunoassay. Clin Chem25:752-756
21. PainsonJ-C, WengerT, LagaceG, MassonND, ColluR1994Cellular distribution of G-protein Gca in pituitary lactotrophs: effects of dopamine. J Neu-roendocrinol6:447-455
22. MullaneyI, CaulfieldMP, SvobodaP, MilliganG1996Activation, cellular redistribution and enhanced degradation of the G-proteins Gq and Gn by endogenously expressed and transfected phospholipase C-coupled muscarinic Mj acetylcholine receptors. Prog Brain Res109:181-187
23. StryerL, BourneHR1986G proteins: a family of signal transducers. Ann Rev-Cell Biol2:391-419
24. LevisMJ, Bourne, HR1992Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity. J Cell Biol119:1297-1307
25. AlousiAA, JasperJR, InselPA, MotulskyHJ1991Stoichiometry of receptor-Gs-adenylate cyclase interactions. FASEB J5:2300-2303
26. LeiberD, JasperJR, AlousiAA, MartinJ, BernsteinD, InselPA1993Alteration in Gs-mediated signal transduction in S49 lymphoma cells treated with inhibitors of microtubules. J Biol Chem268:3833-3837
27. LevisMJ, Bourne, HR1992Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity. J Cell Biol119:1297-307