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Volumn 74, Issue 1, 2017, Pages 41-49

Association of amyloid pathology with myelin alteration in preclinical Alzheimer disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E4; MYELIN; TAU PROTEIN; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); APOLIPOPROTEIN E; BIOLOGICAL MARKER; PEPTIDE FRAGMENT; WATER;

EID: 85011372928     PISSN: 21686149     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaneurol.2016.3232     Document Type: Article
Times cited : (152)

References (40)
  • 1
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 2002;297(5580): 353-356.
    • (2002) Science. , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 2
    • 34247198450 scopus 로고    scopus 로고
    • Human brain myelination and amyloid beta deposition in Alzheimer's disease
    • Bartzokis G, Lu PH, Mintz J. Human brain myelination and amyloid beta deposition in Alzheimer's disease. Alzheimers Dement. 2007;3 (2):122-125.
    • (2007) Alzheimers Dement. , vol.3 , Issue.2 , pp. 122-125
    • Bartzokis, G.1    Lu, P.H.2    Mintz, J.3
  • 3
    • 84882395407 scopus 로고    scopus 로고
    • Dissociable effects of Alzheimer disease and white matter hyperintensities on brain metabolism
    • Alzheimer's Disease Neuroimaging Initiative
    • Haight TJ, Landau SM, Carmichael O, Schwarz C, DeCarli C, JagustWJ; Alzheimer's Disease Neuroimaging Initiative. Dissociable effects of Alzheimer disease and white matter hyperintensities on brain metabolism. JAMA Neurol. 2013;70(8):1039-1045.
    • (2013) JAMA Neurol. , vol.70 , Issue.8 , pp. 1039-1045
    • Haight, T.J.1    Landau, S.M.2    Carmichael, O.3    Schwarz, C.4    DeCarli, C.5    Jagust, W.J.6
  • 4
    • 84862027790 scopus 로고    scopus 로고
    • CSF t-tau/Aβ42 predicts white matter microstructure in healthy adults at risk for Alzheimer's disease
    • Bendlin BB, Carlsson CM, Johnson SC, et al. CSF t-tau/Aβ42 predicts white matter microstructure in healthy adults at risk for Alzheimer's disease. PLoS One. 2012;7(6):e37720.
    • (2012) PLoS One. , vol.7 , Issue.6 , pp. e37720
    • Bendlin, B.B.1    Carlsson, C.M.2    Johnson, S.C.3
  • 5
    • 79959599177 scopus 로고    scopus 로고
    • Alzheimer's disease as homeostatic responses to age-relatedmyelin breakdown
    • Bartzokis G. Alzheimer's disease as homeostatic responses to age-relatedmyelin breakdown. Neurobiol Aging. 2011;32(8):1341-1371.
    • (2011) Neurobiol Aging. , vol.32 , Issue.8 , pp. 1341-1371
    • Bartzokis, G.1
  • 6
    • 18544386562 scopus 로고    scopus 로고
    • Increased A β peptides and reduced cholesterol andmyelin proteins characterize white matter degeneration in Alzheimer's disease
    • Roher AE,Weiss N, Kokjohn TA, et al. Increased A β peptides and reduced cholesterol andmyelin proteins characterize white matter degeneration in Alzheimer's disease. Biochemistry. 2002;41(37): 11080-11090.
    • (2002) Biochemistry. , vol.41 , Issue.37 , pp. 11080-11090
    • Roher, A.E.1    Weiss, N.2    Kokjohn, T.A.3
  • 7
    • 0242627597 scopus 로고    scopus 로고
    • Cerebrospinal fluid markers for prediction of Alzheimer's disease
    • Zetterberg H,Wahlund L-O, Blennow K. Cerebrospinal fluid markers for prediction of Alzheimer's disease. Neurosci Lett. 2003;352(1):67-69.
    • (2003) Neurosci Lett. , vol.352 , Issue.1 , pp. 67-69
    • Zetterberg, H.1    Wahlund, L.-O.2    Blennow, K.3
  • 8
    • 0141738373 scopus 로고    scopus 로고
    • CSF markers for incipient Alzheimer's disease
    • Blennow K, Hampel H. CSF markers for incipient Alzheimer's disease. Lancet Neurol. 2003;2(10): 605-613.
    • (2003) Lancet Neurol. , vol.2 , Issue.10 , pp. 605-613
    • Blennow, K.1    Hampel, H.2
  • 9
    • 79955438992 scopus 로고    scopus 로고
    • Developing predictive CSF biomarkers-A challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine
    • Flood DG, Marek GJ, Williams M. Developing predictive CSF biomarkers-A challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine. Biochem Pharmacol. 2011;81 (12):1422-1434.
    • (2011) Biochem Pharmacol. , vol.81 , Issue.12 , pp. 1422-1434
    • Flood, D.G.1    Marek, G.J.2    Williams, M.3
  • 10
    • 3142743789 scopus 로고    scopus 로고
    • Value of CSF beta-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment
    • Hampel H, Teipel SJ, Fuchsberger T, et al. Value of CSF beta-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment. Mol Psychiatry. 2004;9(7):705-710.
    • (2004) Mol Psychiatry. , vol.9 , Issue.7 , pp. 705-710
    • Hampel, H.1    Teipel, S.J.2    Fuchsberger, T.3
  • 11
    • 79959232075 scopus 로고    scopus 로고
    • Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders
    • Glodzik L, de Santi S, Tsui WH, et al. Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders. Neurobiol Aging. 2011;32(12):2131-2141.
    • (2011) Neurobiol Aging. , vol.32 , Issue.12 , pp. 2131-2141
    • Glodzik, L.1    De Santi, S.2    Tsui, W.H.3
  • 12
    • 84875234773 scopus 로고    scopus 로고
    • White matter integrity, fiber count, and other fallacies: The do's and dont's of diffusion MRI
    • Jones DK, Knösche TR, Turner R. White matter integrity, fiber count, and other fallacies: the do's and dont's of diffusion MRI. Neuroimage. 2013;73: 239-254.
    • (2013) Neuroimage. , vol.73 , pp. 239-254
    • Jones, D.K.1    Knösche, T.R.2    Turner, R.3
  • 13
    • 0346770038 scopus 로고    scopus 로고
    • Age-relatedmyelin breakdown: A developmental model of cognitive decline and Alzheimer's disease
    • Bartzokis G. Age-relatedmyelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol Aging. 2004;25(1):5-18.
    • (2004) Neurobiol Aging. , vol.25 , Issue.1 , pp. 5-18
    • Bartzokis, G.1
  • 14
    • 0028338642 scopus 로고
    • In vivo visualization ofmyelin water in brain by magnetic resonance
    • MacKay A, Whittall K, Adler J, Li D, Paty D, Graeb D. In vivo visualization ofmyelin water in brain by magnetic resonance. Magn Reson Med. 1994;31(6):673-677.
    • (1994) Magn Reson Med. , vol.31 , Issue.6 , pp. 673-677
    • MacKay, A.1    Whittall, K.2    Adler, J.3    Li, D.4    Paty, D.5    Graeb, D.6
  • 15
    • 57149110446 scopus 로고    scopus 로고
    • Gleaning multicomponent T1 and T2 information from steady-state imaging data
    • Deoni SCL, Rutt BK, Arun T, Pierpaoli C, Jones DK. Gleaning multicomponent T1 and T2 information from steady-state imaging data. Magn Reson Med. 2008;60(6):1372-1387.
    • (2008) Magn Reson Med. , vol.60 , Issue.6 , pp. 1372-1387
    • Deoni, S.C.L.1    Rutt, B.K.2    Arun, T.3    Pierpaoli, C.4    Jones, D.K.5
  • 16
    • 77949423619 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma biomarkers in Alzheimer's disease
    • Blennow K, Hampel H,Weiner M, Zetterberg H. Cerebrospinal fluid and plasma biomarkers in Alzheimer's disease. Nat Rev Neurol. 2010;6(3):131-144.
    • (2010) Nat Rev Neurol. , vol.6 , Issue.3 , pp. 131-144
    • Blennow, K.1    Hampel, H.2    Weiner, M.3    Zetterberg, H.4
  • 17
    • 28444490337 scopus 로고    scopus 로고
    • Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer Prevention
    • Sager MA, Hermann B, La Rue A. Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer Prevention. J Geriatr Psychiatry Neurol. 2005;18(4):245-249.
    • (2005) J Geriatr Psychiatry Neurol. , vol.18 , Issue.4 , pp. 245-249
    • Sager, M.A.1    Hermann, B.2    La Rue, A.3
  • 18
    • 84879414396 scopus 로고    scopus 로고
    • One component? Two components? Three? The effect of including a nonexchanging "free" water component in multicomponent driven equilibrium single pulse observation of T1 and T2
    • Deoni SCL, Matthews L, Kolind SH. One component? two components? three? the effect of including a nonexchanging "free" water component in multicomponent driven equilibrium single pulse observation of T1 and T2. Magn Reson Med. 2013; 70(1):147-154.
    • (2013) Magn Reson Med. , vol.70 , Issue.1 , pp. 147-154
    • Deoni, S.C.L.1    Matthews, L.2    Kolind, S.H.3
  • 19
    • 0016823810 scopus 로고
    • "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198.
    • (1975) J Psychiatr Res. , vol.12 , Issue.3 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 20
    • 84907978955 scopus 로고    scopus 로고
    • Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: A cross-validation study against amyloid positron emission tomography
    • Palmqvist S, Zetterberg H, Blennow K, et al. Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: a cross-validation study against amyloid positron emission tomography. JAMA Neurol. 2014;71(10): 1282-1289.
    • (2014) JAMA Neurol. , vol.71 , Issue.10 , pp. 1282-1289
    • Palmqvist, S.1    Zetterberg, H.2    Blennow, K.3
  • 21
    • 79952574501 scopus 로고    scopus 로고
    • Epidemiology of Alzheimer disease
    • Reitz C, Brayne C, Mayeux R. Epidemiology of Alzheimer disease. Nat Rev Neurol. 2011;7(3):137-152.
    • (2011) Nat Rev Neurol. , vol.7 , Issue.3 , pp. 137-152
    • Reitz, C.1    Brayne, C.2    Mayeux, R.3
  • 22
    • 84963641621 scopus 로고    scopus 로고
    • R Core Team, Vienna, Austria: R Foundation for Statistical Computing. Accessed April 20, 2016
    • R Core Team. R: a language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2014. http://www.R-project.org. Accessed April 20, 2016.
    • (2014) R: A Language and Environment for Statistical Computing
  • 23
    • 77952003929 scopus 로고    scopus 로고
    • White matter in aging and cognition: A cross-sectional study of microstructure in adults aged eighteen to eighty-three
    • Bendlin BB, Fitzgerald ME, RiesML, et al. White matter in aging and cognition: a cross-sectional study of microstructure in adults aged eighteen to eighty-three. Dev Neuropsychol. 2010;35(3):257-277.
    • (2010) Dev Neuropsychol. , vol.35 , Issue.3 , pp. 257-277
    • Bendlin, B.B.1    Fitzgerald, M.E.2    Ries, M.L.3
  • 24
    • 85011417703 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Accessed October 16, 2015
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B. 1995;57(1):289-300. https://www.jstor.org/stable/2346101. Accessed October 16, 2015.
    • (1995) J R Stat Soc ser B. , vol.57 , Issue.1 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 26
    • 0346220384 scopus 로고    scopus 로고
    • Quadratic trajectories of brain myelin content: Unifying construct for neuropsychiatric disorders
    • Bartzokis G. Quadratic trajectories of brain myelin content: unifying construct for neuropsychiatric disorders. Neurobiol Aging. 2004; 25(1):49-62.
    • (2004) Neurobiol Aging. , vol.25 , Issue.1 , pp. 49-62
    • Bartzokis, G.1
  • 27
    • 77954174225 scopus 로고    scopus 로고
    • 3D maps localize caudate nucleus atrophy in 400 Alzheimer's disease, mild cognitive impairment, and healthy elderly subjects
    • Alzheimer's Disease Neuroimaging Initiative
    • Madsen SK, Ho AJ, Hua X, et al; Alzheimer's Disease Neuroimaging Initiative. 3D maps localize caudate nucleus atrophy in 400 Alzheimer's disease, mild cognitive impairment, and healthy elderly subjects. Neurobiol Aging. 2010;31(8):1312-1325.
    • (2010) Neurobiol Aging. , vol.31 , Issue.8 , pp. 1312-1325
    • Madsen, S.K.1    Ho, A.J.2    Hua, X.3
  • 28
    • 13444301246 scopus 로고    scopus 로고
    • Quantifying age-relatedmyelin breakdown with MRI: Novel therapeutic targets for preventing cognitive decline and Alzheimer's disease
    • Bartzokis G, Lu PH, Mintz J. Quantifying age-relatedmyelin breakdown with MRI: novel therapeutic targets for preventing cognitive decline and Alzheimer's disease. J Alzheimers Dis. 2004;6 (6)(suppl):53-59.
    • (2004) J Alzheimers Dis. , vol.6 , Issue.6 , pp. 53-59
    • Bartzokis, G.1    Lu, P.H.2    Mintz, J.3
  • 29
    • 84866024322 scopus 로고    scopus 로고
    • Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping
    • Deoni SCL, Dean DC III, O'Muircheartaigh J, Dirks H, Jerskey BA. Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping. Neuroimage. 2012;63(3):1038-1053.
    • (2012) Neuroimage. , vol.63 , Issue.3 , pp. 1038-1053
    • Deoni, S.C.L.1    Dean, D.C.2    O'Muircheartaigh, J.3    Dirks, H.4    Jerskey, B.A.5
  • 30
    • 84933180941 scopus 로고    scopus 로고
    • Characterizing longitudinal white matter development during early childhood
    • Dean DC III, O'Muircheartaigh J, Dirks H, et al. Characterizing longitudinal white matter development during early childhood. Brain Struct Funct. 2015;220(4):1921-1933.
    • (2015) Brain Struct Funct. , vol.220 , Issue.4 , pp. 1921-1933
    • Dean, D.C.1    O'Muircheartaigh, J.2    Dirks, H.3
  • 31
    • 84952898119 scopus 로고    scopus 로고
    • The preclinical phase of the pathological process underlying sporadic Alzheimer's disease
    • Braak H, Del Tredici K. The preclinical phase of the pathological process underlying sporadic Alzheimer's disease. Brain. 2015;138(pt 10):2814-2833.
    • (2015) Brain. , vol.138 , pp. 2814-2833
    • Braak, H.1    Del Tredici, K.2
  • 32
    • 0033305929 scopus 로고    scopus 로고
    • Brain development during childhood and adolescence: A longitudinal MRI study
    • Giedd JN, Blumenthal J, Jeffries NO, et al. Brain development during childhood and adolescence: a longitudinal MRI study. Nat Neurosci. 1999;2(10): 861-863.
    • (1999) Nat Neurosci. , vol.2 , Issue.10 , pp. 861-863
    • Giedd, J.N.1    Blumenthal, J.2    Jeffries, N.O.3
  • 33
    • 70350366775 scopus 로고    scopus 로고
    • Degradation of amyloid beta protein by purifiedmyelin basic protein
    • Liao M-C, Ahmed M, Smith SO, Van Nostrand WE. Degradation of amyloid beta protein by purifiedmyelin basic protein. J Biol Chem. 2009; 284(42):28917-28925.
    • (2009) J Biol Chem. , vol.284 , Issue.42 , pp. 28917-28925
    • Liao, M.-C.1    Ahmed, M.2    Smith, S.O.3    Van Nostrand, W.E.4
  • 34
    • 66649118037 scopus 로고    scopus 로고
    • Myelin basic protein binds to and inhibits the fibrillar assembly of Aβ42 in vitro
    • Hoos MD, Ahmed M, Smith SO, Van Nostrand WE.Myelin basic protein binds to and inhibits the fibrillar assembly of Aβ42 in vitro. Biochemistry. 2009;48(22):4720-4727.
    • (2009) Biochemistry. , vol.48 , Issue.22 , pp. 4720-4727
    • Hoos, M.D.1    Ahmed, M.2    Smith, S.O.3    Van Nostrand, W.E.4
  • 35
    • 0345276565 scopus 로고    scopus 로고
    • Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
    • Mandelkow EM, Stamer K, Vogel R, Thies E, Mandelkow E. Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging. 2003;24(8):1079-1085.
    • (2003) Neurobiol Aging. , vol.24 , Issue.8 , pp. 1079-1085
    • Mandelkow, E.M.1    Stamer, K.2    Vogel, R.3    Thies, E.4    Mandelkow, E.5
  • 36
    • 61449120013 scopus 로고    scopus 로고
    • Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brainmyelination patterns prior to appearance of amyloid and tau pathology
    • Desai MK, Sudol KL, Janelsins MC, Mastrangelo MA, FrazerME, BowersWJ. Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brainmyelination patterns prior to appearance of amyloid and tau pathology. Glia. 2009;57(1):54-65.
    • (2009) Glia. , vol.57 , Issue.1 , pp. 54-65
    • Desai, M.K.1    Sudol, K.L.2    Janelsins, M.C.3    Mastrangelo, M.A.4    Frazer, M.E.5    Bowers, W.J.6
  • 37
    • 78651513021 scopus 로고    scopus 로고
    • Multicomponent relaxometry (mcDESPOT) in the shaking pup model of dysmyelination
    • 2010 Annual Meeting; May 6; Stockholm, Sweden. Accessed March 15, 2016.
    • Hurley SA, Mossahebi PM, Samsonov AA. Multicomponent relaxometry (mcDESPOT) in the shaking pup model of dysmyelination. Paper presented at: International Society forMagnetic Resonance in Medicine 2010 Annual Meeting; May 6, 2010; Stockholm, Sweden. http://cds.ismrm .org/protected/10MProceedings/files/4516-88.pdf. Accessed March 15, 2016.
    • (2010) International Society ForMagnetic Resonance in Medicine
    • Hurley, S.A.1    Mossahebi, P.M.2    Samsonov, A.A.3
  • 38
    • 84855452907 scopus 로고    scopus 로고
    • Deficient MWF mapping in multiple sclerosis using 3D whole-brain multi-component relaxation MRI
    • Kitzler HH, Su J, Zeineh M, et al. Deficient MWF mapping in multiple sclerosis using 3D whole-brain multi-component relaxation MRI. Neuroimage. 2012;59(3):2670-2677.
    • (2012) Neuroimage. , vol.59 , Issue.3 , pp. 2670-2677
    • Kitzler, H.H.1    Su, J.2    Zeineh, M.3
  • 39
    • 84863411998 scopus 로고    scopus 로고
    • Myelin water imaging reflects clinical variability in multiple sclerosis
    • Kolind S, Matthews L, Johansen-Berg H, et al. Myelin water imaging reflects clinical variability in multiple sclerosis. Neuroimage. 2012;60(1):263-270.
    • (2012) Neuroimage. , vol.60 , Issue.1 , pp. 263-270
    • Kolind, S.1    Matthews, L.2    Johansen-Berg, H.3
  • 40
    • 84876405432 scopus 로고    scopus 로고
    • Advances inmyelin imaging with potential clinical application to pediatric imaging
    • Spader HS, Ellermeier A, O'Muircheartaigh J, et al. Advances inmyelin imaging with potential clinical application to pediatric imaging. Neurosurg Focus. 2013;34(4):E9.
    • (2013) Neurosurg Focus. , vol.34 , Issue.4 , pp. E9
    • Spader, H.S.1    Ellermeier, A.2    O'Muircheartaigh, J.3


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