-
1
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 2002;297(5580): 353-356.
-
(2002)
Science.
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
2
-
-
34247198450
-
Human brain myelination and amyloid beta deposition in Alzheimer's disease
-
Bartzokis G, Lu PH, Mintz J. Human brain myelination and amyloid beta deposition in Alzheimer's disease. Alzheimers Dement. 2007;3 (2):122-125.
-
(2007)
Alzheimers Dement.
, vol.3
, Issue.2
, pp. 122-125
-
-
Bartzokis, G.1
Lu, P.H.2
Mintz, J.3
-
3
-
-
84882395407
-
Dissociable effects of Alzheimer disease and white matter hyperintensities on brain metabolism
-
Alzheimer's Disease Neuroimaging Initiative
-
Haight TJ, Landau SM, Carmichael O, Schwarz C, DeCarli C, JagustWJ; Alzheimer's Disease Neuroimaging Initiative. Dissociable effects of Alzheimer disease and white matter hyperintensities on brain metabolism. JAMA Neurol. 2013;70(8):1039-1045.
-
(2013)
JAMA Neurol.
, vol.70
, Issue.8
, pp. 1039-1045
-
-
Haight, T.J.1
Landau, S.M.2
Carmichael, O.3
Schwarz, C.4
DeCarli, C.5
Jagust, W.J.6
-
4
-
-
84862027790
-
CSF t-tau/Aβ42 predicts white matter microstructure in healthy adults at risk for Alzheimer's disease
-
Bendlin BB, Carlsson CM, Johnson SC, et al. CSF t-tau/Aβ42 predicts white matter microstructure in healthy adults at risk for Alzheimer's disease. PLoS One. 2012;7(6):e37720.
-
(2012)
PLoS One.
, vol.7
, Issue.6
, pp. e37720
-
-
Bendlin, B.B.1
Carlsson, C.M.2
Johnson, S.C.3
-
5
-
-
79959599177
-
Alzheimer's disease as homeostatic responses to age-relatedmyelin breakdown
-
Bartzokis G. Alzheimer's disease as homeostatic responses to age-relatedmyelin breakdown. Neurobiol Aging. 2011;32(8):1341-1371.
-
(2011)
Neurobiol Aging.
, vol.32
, Issue.8
, pp. 1341-1371
-
-
Bartzokis, G.1
-
6
-
-
18544386562
-
Increased A β peptides and reduced cholesterol andmyelin proteins characterize white matter degeneration in Alzheimer's disease
-
Roher AE,Weiss N, Kokjohn TA, et al. Increased A β peptides and reduced cholesterol andmyelin proteins characterize white matter degeneration in Alzheimer's disease. Biochemistry. 2002;41(37): 11080-11090.
-
(2002)
Biochemistry.
, vol.41
, Issue.37
, pp. 11080-11090
-
-
Roher, A.E.1
Weiss, N.2
Kokjohn, T.A.3
-
7
-
-
0242627597
-
Cerebrospinal fluid markers for prediction of Alzheimer's disease
-
Zetterberg H,Wahlund L-O, Blennow K. Cerebrospinal fluid markers for prediction of Alzheimer's disease. Neurosci Lett. 2003;352(1):67-69.
-
(2003)
Neurosci Lett.
, vol.352
, Issue.1
, pp. 67-69
-
-
Zetterberg, H.1
Wahlund, L.-O.2
Blennow, K.3
-
8
-
-
0141738373
-
CSF markers for incipient Alzheimer's disease
-
Blennow K, Hampel H. CSF markers for incipient Alzheimer's disease. Lancet Neurol. 2003;2(10): 605-613.
-
(2003)
Lancet Neurol.
, vol.2
, Issue.10
, pp. 605-613
-
-
Blennow, K.1
Hampel, H.2
-
9
-
-
79955438992
-
Developing predictive CSF biomarkers-A challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine
-
Flood DG, Marek GJ, Williams M. Developing predictive CSF biomarkers-A challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine. Biochem Pharmacol. 2011;81 (12):1422-1434.
-
(2011)
Biochem Pharmacol.
, vol.81
, Issue.12
, pp. 1422-1434
-
-
Flood, D.G.1
Marek, G.J.2
Williams, M.3
-
10
-
-
3142743789
-
Value of CSF beta-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment
-
Hampel H, Teipel SJ, Fuchsberger T, et al. Value of CSF beta-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment. Mol Psychiatry. 2004;9(7):705-710.
-
(2004)
Mol Psychiatry.
, vol.9
, Issue.7
, pp. 705-710
-
-
Hampel, H.1
Teipel, S.J.2
Fuchsberger, T.3
-
11
-
-
79959232075
-
Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders
-
Glodzik L, de Santi S, Tsui WH, et al. Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders. Neurobiol Aging. 2011;32(12):2131-2141.
-
(2011)
Neurobiol Aging.
, vol.32
, Issue.12
, pp. 2131-2141
-
-
Glodzik, L.1
De Santi, S.2
Tsui, W.H.3
-
12
-
-
84875234773
-
White matter integrity, fiber count, and other fallacies: The do's and dont's of diffusion MRI
-
Jones DK, Knösche TR, Turner R. White matter integrity, fiber count, and other fallacies: the do's and dont's of diffusion MRI. Neuroimage. 2013;73: 239-254.
-
(2013)
Neuroimage.
, vol.73
, pp. 239-254
-
-
Jones, D.K.1
Knösche, T.R.2
Turner, R.3
-
13
-
-
0346770038
-
Age-relatedmyelin breakdown: A developmental model of cognitive decline and Alzheimer's disease
-
Bartzokis G. Age-relatedmyelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol Aging. 2004;25(1):5-18.
-
(2004)
Neurobiol Aging.
, vol.25
, Issue.1
, pp. 5-18
-
-
Bartzokis, G.1
-
14
-
-
0028338642
-
In vivo visualization ofmyelin water in brain by magnetic resonance
-
MacKay A, Whittall K, Adler J, Li D, Paty D, Graeb D. In vivo visualization ofmyelin water in brain by magnetic resonance. Magn Reson Med. 1994;31(6):673-677.
-
(1994)
Magn Reson Med.
, vol.31
, Issue.6
, pp. 673-677
-
-
MacKay, A.1
Whittall, K.2
Adler, J.3
Li, D.4
Paty, D.5
Graeb, D.6
-
15
-
-
57149110446
-
Gleaning multicomponent T1 and T2 information from steady-state imaging data
-
Deoni SCL, Rutt BK, Arun T, Pierpaoli C, Jones DK. Gleaning multicomponent T1 and T2 information from steady-state imaging data. Magn Reson Med. 2008;60(6):1372-1387.
-
(2008)
Magn Reson Med.
, vol.60
, Issue.6
, pp. 1372-1387
-
-
Deoni, S.C.L.1
Rutt, B.K.2
Arun, T.3
Pierpaoli, C.4
Jones, D.K.5
-
16
-
-
77949423619
-
Cerebrospinal fluid and plasma biomarkers in Alzheimer's disease
-
Blennow K, Hampel H,Weiner M, Zetterberg H. Cerebrospinal fluid and plasma biomarkers in Alzheimer's disease. Nat Rev Neurol. 2010;6(3):131-144.
-
(2010)
Nat Rev Neurol.
, vol.6
, Issue.3
, pp. 131-144
-
-
Blennow, K.1
Hampel, H.2
Weiner, M.3
Zetterberg, H.4
-
17
-
-
28444490337
-
Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer Prevention
-
Sager MA, Hermann B, La Rue A. Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer Prevention. J Geriatr Psychiatry Neurol. 2005;18(4):245-249.
-
(2005)
J Geriatr Psychiatry Neurol.
, vol.18
, Issue.4
, pp. 245-249
-
-
Sager, M.A.1
Hermann, B.2
La Rue, A.3
-
18
-
-
84879414396
-
One component? Two components? Three? The effect of including a nonexchanging "free" water component in multicomponent driven equilibrium single pulse observation of T1 and T2
-
Deoni SCL, Matthews L, Kolind SH. One component? two components? three? the effect of including a nonexchanging "free" water component in multicomponent driven equilibrium single pulse observation of T1 and T2. Magn Reson Med. 2013; 70(1):147-154.
-
(2013)
Magn Reson Med.
, vol.70
, Issue.1
, pp. 147-154
-
-
Deoni, S.C.L.1
Matthews, L.2
Kolind, S.H.3
-
19
-
-
0016823810
-
"Mini-mental state": A practical method for grading the cognitive state of patients for the clinician
-
Folstein MF, Folstein SE, McHugh PR. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198.
-
(1975)
J Psychiatr Res.
, vol.12
, Issue.3
, pp. 189-198
-
-
Folstein, M.F.1
Folstein, S.E.2
McHugh, P.R.3
-
20
-
-
84907978955
-
Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: A cross-validation study against amyloid positron emission tomography
-
Palmqvist S, Zetterberg H, Blennow K, et al. Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: a cross-validation study against amyloid positron emission tomography. JAMA Neurol. 2014;71(10): 1282-1289.
-
(2014)
JAMA Neurol.
, vol.71
, Issue.10
, pp. 1282-1289
-
-
Palmqvist, S.1
Zetterberg, H.2
Blennow, K.3
-
22
-
-
84963641621
-
-
R Core Team, Vienna, Austria: R Foundation for Statistical Computing. Accessed April 20, 2016
-
R Core Team. R: a language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2014. http://www.R-project.org. Accessed April 20, 2016.
-
(2014)
R: A Language and Environment for Statistical Computing
-
-
-
23
-
-
77952003929
-
White matter in aging and cognition: A cross-sectional study of microstructure in adults aged eighteen to eighty-three
-
Bendlin BB, Fitzgerald ME, RiesML, et al. White matter in aging and cognition: a cross-sectional study of microstructure in adults aged eighteen to eighty-three. Dev Neuropsychol. 2010;35(3):257-277.
-
(2010)
Dev Neuropsychol.
, vol.35
, Issue.3
, pp. 257-277
-
-
Bendlin, B.B.1
Fitzgerald, M.E.2
Ries, M.L.3
-
24
-
-
85011417703
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Accessed October 16, 2015
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B. 1995;57(1):289-300. https://www.jstor.org/stable/2346101. Accessed October 16, 2015.
-
(1995)
J R Stat Soc ser B.
, vol.57
, Issue.1
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
25
-
-
33646121492
-
Insights into brain microstructure from the T2 distribution
-
MacKay A, Laule C, Vavasour I, Bjarnason T, Kolind S, Mädler B. Insights into brain microstructure from the T2 distribution. Magn Reson Imaging. 2006;24(4):515-525.
-
(2006)
Magn Reson Imaging.
, vol.24
, Issue.4
, pp. 515-525
-
-
MacKay, A.1
Laule, C.2
Vavasour, I.3
Bjarnason, T.4
Kolind, S.5
Mädler, B.6
-
26
-
-
0346220384
-
Quadratic trajectories of brain myelin content: Unifying construct for neuropsychiatric disorders
-
Bartzokis G. Quadratic trajectories of brain myelin content: unifying construct for neuropsychiatric disorders. Neurobiol Aging. 2004; 25(1):49-62.
-
(2004)
Neurobiol Aging.
, vol.25
, Issue.1
, pp. 49-62
-
-
Bartzokis, G.1
-
27
-
-
77954174225
-
3D maps localize caudate nucleus atrophy in 400 Alzheimer's disease, mild cognitive impairment, and healthy elderly subjects
-
Alzheimer's Disease Neuroimaging Initiative
-
Madsen SK, Ho AJ, Hua X, et al; Alzheimer's Disease Neuroimaging Initiative. 3D maps localize caudate nucleus atrophy in 400 Alzheimer's disease, mild cognitive impairment, and healthy elderly subjects. Neurobiol Aging. 2010;31(8):1312-1325.
-
(2010)
Neurobiol Aging.
, vol.31
, Issue.8
, pp. 1312-1325
-
-
Madsen, S.K.1
Ho, A.J.2
Hua, X.3
-
28
-
-
13444301246
-
Quantifying age-relatedmyelin breakdown with MRI: Novel therapeutic targets for preventing cognitive decline and Alzheimer's disease
-
Bartzokis G, Lu PH, Mintz J. Quantifying age-relatedmyelin breakdown with MRI: novel therapeutic targets for preventing cognitive decline and Alzheimer's disease. J Alzheimers Dis. 2004;6 (6)(suppl):53-59.
-
(2004)
J Alzheimers Dis.
, vol.6
, Issue.6
, pp. 53-59
-
-
Bartzokis, G.1
Lu, P.H.2
Mintz, J.3
-
29
-
-
84866024322
-
Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping
-
Deoni SCL, Dean DC III, O'Muircheartaigh J, Dirks H, Jerskey BA. Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping. Neuroimage. 2012;63(3):1038-1053.
-
(2012)
Neuroimage.
, vol.63
, Issue.3
, pp. 1038-1053
-
-
Deoni, S.C.L.1
Dean, D.C.2
O'Muircheartaigh, J.3
Dirks, H.4
Jerskey, B.A.5
-
30
-
-
84933180941
-
Characterizing longitudinal white matter development during early childhood
-
Dean DC III, O'Muircheartaigh J, Dirks H, et al. Characterizing longitudinal white matter development during early childhood. Brain Struct Funct. 2015;220(4):1921-1933.
-
(2015)
Brain Struct Funct.
, vol.220
, Issue.4
, pp. 1921-1933
-
-
Dean, D.C.1
O'Muircheartaigh, J.2
Dirks, H.3
-
31
-
-
84952898119
-
The preclinical phase of the pathological process underlying sporadic Alzheimer's disease
-
Braak H, Del Tredici K. The preclinical phase of the pathological process underlying sporadic Alzheimer's disease. Brain. 2015;138(pt 10):2814-2833.
-
(2015)
Brain.
, vol.138
, pp. 2814-2833
-
-
Braak, H.1
Del Tredici, K.2
-
32
-
-
0033305929
-
Brain development during childhood and adolescence: A longitudinal MRI study
-
Giedd JN, Blumenthal J, Jeffries NO, et al. Brain development during childhood and adolescence: a longitudinal MRI study. Nat Neurosci. 1999;2(10): 861-863.
-
(1999)
Nat Neurosci.
, vol.2
, Issue.10
, pp. 861-863
-
-
Giedd, J.N.1
Blumenthal, J.2
Jeffries, N.O.3
-
33
-
-
70350366775
-
Degradation of amyloid beta protein by purifiedmyelin basic protein
-
Liao M-C, Ahmed M, Smith SO, Van Nostrand WE. Degradation of amyloid beta protein by purifiedmyelin basic protein. J Biol Chem. 2009; 284(42):28917-28925.
-
(2009)
J Biol Chem.
, vol.284
, Issue.42
, pp. 28917-28925
-
-
Liao, M.-C.1
Ahmed, M.2
Smith, S.O.3
Van Nostrand, W.E.4
-
34
-
-
66649118037
-
Myelin basic protein binds to and inhibits the fibrillar assembly of Aβ42 in vitro
-
Hoos MD, Ahmed M, Smith SO, Van Nostrand WE.Myelin basic protein binds to and inhibits the fibrillar assembly of Aβ42 in vitro. Biochemistry. 2009;48(22):4720-4727.
-
(2009)
Biochemistry.
, vol.48
, Issue.22
, pp. 4720-4727
-
-
Hoos, M.D.1
Ahmed, M.2
Smith, S.O.3
Van Nostrand, W.E.4
-
35
-
-
0345276565
-
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
-
Mandelkow EM, Stamer K, Vogel R, Thies E, Mandelkow E. Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging. 2003;24(8):1079-1085.
-
(2003)
Neurobiol Aging.
, vol.24
, Issue.8
, pp. 1079-1085
-
-
Mandelkow, E.M.1
Stamer, K.2
Vogel, R.3
Thies, E.4
Mandelkow, E.5
-
36
-
-
61449120013
-
Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brainmyelination patterns prior to appearance of amyloid and tau pathology
-
Desai MK, Sudol KL, Janelsins MC, Mastrangelo MA, FrazerME, BowersWJ. Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brainmyelination patterns prior to appearance of amyloid and tau pathology. Glia. 2009;57(1):54-65.
-
(2009)
Glia.
, vol.57
, Issue.1
, pp. 54-65
-
-
Desai, M.K.1
Sudol, K.L.2
Janelsins, M.C.3
Mastrangelo, M.A.4
Frazer, M.E.5
Bowers, W.J.6
-
37
-
-
78651513021
-
Multicomponent relaxometry (mcDESPOT) in the shaking pup model of dysmyelination
-
2010 Annual Meeting; May 6; Stockholm, Sweden. Accessed March 15, 2016.
-
Hurley SA, Mossahebi PM, Samsonov AA. Multicomponent relaxometry (mcDESPOT) in the shaking pup model of dysmyelination. Paper presented at: International Society forMagnetic Resonance in Medicine 2010 Annual Meeting; May 6, 2010; Stockholm, Sweden. http://cds.ismrm .org/protected/10MProceedings/files/4516-88.pdf. Accessed March 15, 2016.
-
(2010)
International Society ForMagnetic Resonance in Medicine
-
-
Hurley, S.A.1
Mossahebi, P.M.2
Samsonov, A.A.3
-
38
-
-
84855452907
-
Deficient MWF mapping in multiple sclerosis using 3D whole-brain multi-component relaxation MRI
-
Kitzler HH, Su J, Zeineh M, et al. Deficient MWF mapping in multiple sclerosis using 3D whole-brain multi-component relaxation MRI. Neuroimage. 2012;59(3):2670-2677.
-
(2012)
Neuroimage.
, vol.59
, Issue.3
, pp. 2670-2677
-
-
Kitzler, H.H.1
Su, J.2
Zeineh, M.3
-
39
-
-
84863411998
-
Myelin water imaging reflects clinical variability in multiple sclerosis
-
Kolind S, Matthews L, Johansen-Berg H, et al. Myelin water imaging reflects clinical variability in multiple sclerosis. Neuroimage. 2012;60(1):263-270.
-
(2012)
Neuroimage.
, vol.60
, Issue.1
, pp. 263-270
-
-
Kolind, S.1
Matthews, L.2
Johansen-Berg, H.3
-
40
-
-
84876405432
-
Advances inmyelin imaging with potential clinical application to pediatric imaging
-
Spader HS, Ellermeier A, O'Muircheartaigh J, et al. Advances inmyelin imaging with potential clinical application to pediatric imaging. Neurosurg Focus. 2013;34(4):E9.
-
(2013)
Neurosurg Focus.
, vol.34
, Issue.4
, pp. E9
-
-
Spader, H.S.1
Ellermeier, A.2
O'Muircheartaigh, J.3
|