Click quantitative mass spectrometry identifies PIWIL3 as a mechanistic target of RNA interference activator enoxacin in cancer cells

Journal of the American Chemical Society

Volumn 139, Issue 4, 2017, Pages 1400-1403

  Abell, Nathan S ^a   Mercado, Marvin ^a   Cañeque, Tatiana ^b,c,d   Rodriguez, Raphaël ^b,c,d   Xhemalce, Blerta ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^c INSTITUT CURIE   (France)

^d CNRS UMR3666   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; MASS SPECTROMETRY; RNA; SPECTROMETRY;

ARGONAUTE PROTEINS; CANCER CELLS; ENOXACIN; GERMLINE; GROWTH INHIBITOR; QUANTITATIVE MASS SPECTROMETRIES; RNA INTERFERENCE; SMALL MOLECULES;

DISEASES;

ARGONAUTE PROTEIN; ENOXACIN; PIWIL3; UNCLASSIFIED DRUG; HIWI3 PROTEIN, HUMAN;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; CLICK CHEMISTRY; DRUG SPECIFICITY; DRUG TARGETING; GENE EXPRESSION; HELA CELL LINE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULARLY TARGETED THERAPY; QUANTITATIVE ANALYSIS; RNA INTERFERENCE; ANTAGONISTS AND INHIBITORS; BREAST TUMOR; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; FEMALE; MCF-7 CELL LINE; METABOLISM; PATHOLOGY;

ARGONAUTE PROTEINS; BREAST NEOPLASMS; CELL PROLIFERATION; ENOXACIN; FEMALE; HUMANS; MASS SPECTROMETRY; MCF-7 CELLS; MOLECULAR STRUCTURE;

EID: 85011081954     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.6b11751     Document Type: Article

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