Betanin, isolated from fruits of Opuntia elatior Mill attenuates renal fibrosis in diabetic rats through regulating oxidative stress and TGF-β pathway

Journal of Ethnopharmacology

Volumn 198, Issue , 2017, Pages 432-443

  Sutariya, Brijesh ^a   Saraf, Madhusudan ^a  

^a BOMBAY COLLEGE OF PHARMACY   (India)

Author keywords

Betanin; Diabetic nephropathy; Epithelial to mesenchymal transition; Oxidative stress; Renal fibrosis; Transforming growth factor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIDIABETIC AGENT; BETANIN; CATALASE; COLLAGEN TYPE 4; HERBACEOUS AGENT; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN; BETACYANIN; CREATININE; GLUCOSE BLOOD LEVEL; LISINOPRIL; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES CONTROL; DIABETIC NEPHROPATHY; DIABETOGENESIS; ENZYME ACTIVITY; EXPERIMENTAL DIABETIC NEPHROPATHY; FEMALE; GLUCOSE BLOOD LEVEL; KIDNEY FIBROSIS; KIDNEY FUNCTION; LIPID PEROXIDATION; NONHUMAN; OPUNTIA; OPUNTIA ELATIOR; OXIDATIVE STRESS; PROTEINURIA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; UREA NITROGEN BLOOD LEVEL; URINE VOLUME; ANIMAL; BLOOD; CHEMISTRY; COMPARATIVE STUDY; COMPLICATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DOSE RESPONSE; DRUG EFFECTS; FIBROSIS; FRUIT; ISOLATION AND PURIFICATION; METABOLISM; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; BETACYANINS; BLOOD GLUCOSE; BLOOD UREA NITROGEN; CREATININE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FIBROSIS; FRUIT; LISINOPRIL; OPUNTIA; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 85010966974     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2016.12.048     Document Type: Article

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