Emotion regulation related neural predictors of cognitive behavioral therapy response in social anxiety disorder

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 75, Issue , 2017, Pages 106-112

  Klumpp, Heide ^a   Roberts, Julia ^a   Kennedy, Amy E ^a,b   Shankman, Stewart A ^a   Langenecker, Scott A ^a   Gross, James J ^c   Phan, Luan K ^a,b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b JESSE BROWN VA MEDICAL CENTER   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN FUNCTION; CLINICAL ARTICLE; COGNITION; COGNITIVE BEHAVIORAL THERAPY; DORSOLATERAL PREFRONTAL CORTEX; EMOTIONALITY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MALE; MENTAL TASK; PREDICTIVE VALIDITY; SOCIAL PHOBIA; TREATMENT OUTCOME; TREATMENT RESPONSE; ADOLESCENT; BLOOD; BRAIN MAPPING; COGNITIVE THERAPY; DIAGNOSTIC IMAGING; EMOTION; IMAGE PROCESSING; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOBIA, SOCIAL; PHYSIOLOGY; PREFRONTAL CORTEX; PSYCHOLOGICAL RATING SCALE; RECEIVER OPERATING CHARACTERISTIC; YOUNG ADULT;

OXYGEN;

ADOLESCENT; ADULT; BRAIN MAPPING; COGNITIVE THERAPY; EMOTIONS; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OXYGEN; PHOBIA, SOCIAL; PREFRONTAL CORTEX; PSYCHIATRIC STATUS RATING SCALES; ROC CURVE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 85010850403     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2017.01.010     Document Type: Article

References (59)

1. Arch, J.J., Craske, M.G., First-line treatment: a critical appraisal of cognitive behavioral therapy developments and alternatives. Psychiatr. Clin. North Am. 32 (2009), 525–547.
2. Ball, T.M., Stein, M.B., Ramsawh, H.J., Campbell-Sills, L., Paulus, M.P., Single-subject anxiety treatment outcome prediction using functional neuroimaging. Neuropsychopharmacology 39 (2014), 1254–1261.
3. Bandelow, B., Baldwin, D.S., Dolberg, O.T., Andersen, H.F., Stein, D.J., What is the threshold for symptomatic response and remission for major depressive disorder, panic disorder, social anxiety disorder, and generalized anxiety disorder?. J. Clin. Psychiatry 67 (2006), 1428–1434.
4. Beck, A.T., Steer, R.A., Brown, G.K., Manual for the Beck Depression Inventory-II. 1996, Psychological Corporation, San Antonio, TX.
5. Buhle, J.T., Silvers, J.A., Wager, T.D., Lopez, R., Onyemekwu, C., Kober, H., Weber, J., Ochsner, K.N., Cognitive reappraisal of emotion: a meta-analysis of human neuroimaging studies. Cereb. Cortex 24 (2014), 2981–2990.
6. Chambless, D.L., Tran, G.Q., Glass, C.R., Predictors of response to cognitive-behavioral group therapy for social phobia. J. Anxiety Disord. 11 (1997), 221–240.
7. Cox, R.W., AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput. Biomed. Res. 29 (1996), 162–173.
8. Demenescu, L.R., Kortekaas, R., Cremers, H.R., Renken, R.J., van Tol, M.-J., van der Wee, N.J.A., Veltman, D.J., den Boer, J.A., Roelofs, K., Aleman, A., Amygdala activation and its functional connectivity during perception of emotional faces in social phobia and panic disorder. J. Psychiatr. Res. 47 (2013), 1024–1031.
9. Doehrmann, O., Ghosh, S.S., Polli, F.E., Reynolds, G.O., Horn, F., Keshavan, A., Triantafyllou, C., Saygin, Z.M., Whitfield-Gabrieli, S., Hofmann, S.G., Pollack, M., Gabrieli, J.D., Predicting treatment response in social anxiety disorder from functional magnetic resonance imaging. JAMA Psychiatry 70 (2013), 87–97.
10. Downar, J., Blumberger, D.M., Daskalakis, Z.J., The neural crossroads of psychiatric illness: an emerging target for brain stimulation. Trends Cogn. Sci. 20 (2016), 107–120.
11. Etkin, A., Wager, T.D., Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. Am. J. Psychiatry 164 (2007), 1476–1488.
12. Falconer, E., Allen, A., Felmingham, K.L., Williams, L.M., Bryant, R.A., Inhibitory neural activity predicts response to cognitive-behavioral therapy for posttraumatic stress disorder. J. Clin. Psychiatry 74 (2013), 895–901.
13. First, M., Spitzer, R., Gibbon, M., Williams, J., Structured Clinical Interview for DSM-IV Axis I Disorders. Patient Edition (SCID-P), Version 2, 1995, Biometrics Research, New York, NY.
14. Fu, C.H.Y., Williams, S.C.R., Cleare, A.J., Scott, J., Mitterschiffthaler, M.T., Walsh, N.D., Donaldson, C., Suckling, J., Andrew, C., Steiner, H., Murray, R.M., Neural responses to sad facial expressions in major depression following cognitive behavioral therapy. Biol. Psychiatry 64 (2008), 505–512.
15. Goldin, P.R., Manber-Ball, T., Werner, K., Heimberg, R., Gross, J.J., Neural mechanisms of cognitive reappraisal of negative self-beliefs in social anxiety disorder. Biol. Psychiatry 66 (2009), 1091–1099.
16. Goldin, P., Manber, T., Hakimi, S., Canli, T., Gross, J.J., Neural bases of social anxiety disorder: emotional reactivity and cognitive regulation during social and physical threat. Arch. Gen. Psychiatry 66 (2009), 170–180.
17. Goldin, P.R., Ziv, M., Jazaieri, H., Hahn, K., Heimberg, R., Gross, J.J., Impact of cognitive behavioral therapy for social anxiety disorder on the neural dynamics of cognitive reappraisal of negative self-beliefs: randomized clinical trial. JAMA Psychiatry 70 (2013), 1048–1056.
18. Goldin, P.R., Ziv, M., Jazaieri, H., Weeks, J., Heimberg, R.G., Gross, J.J., Impact of cognitive-behavioral therapy for social anxiety disorder on the neural bases of emotional reactivity to and regulation of social evaluation. Behav. Res. Ther. 62 (2014), 97–106.
19. Gross, J.J., John, O.P., Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being. J. Pers. Soc. Psychol. 85 (2003), 348–362.
20. Hamilton, M., A rating scale for depression. J. Neurol. Neurosurg. Psychiatry 23 (1960), 56–62.
21. Heimberg, R.G., Hofmann, S.G., Liebowitz, M.R., Schneier, F.R., Smits, J.A.J., Stein, M.B., Hinton, D.E., Craske, M.G., Social anxiety disorder in DSM-5. Depress. Anxiety 31 (2014), 472–479.
22. Hofmann, S.G., Cognitive mediation of treatment change in social phobia. J. Consult. Clin. Psychol. 72 (2004), 393–399.
23. Hofmann, S.G., Smits, J.A.J., Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials. J. Clin. Psychiatry 69 (2008), 621–632.
24. Hope, D.A., Heimberg, R.G., Turk, C.L., Managing Social Anxiety: A Cognitive-Behavioral Therapy Approach. first ed., 2006, Oxford University Press, New York, USA.
25. Hoyer, J., Wiltink, J., Hiller, W., Miller, R., Salzer, S., Sarnowsky, S., Stangier, U., Strauss, B., Willutzki, U., Leibing, E., Baseline patient characteristics predicting outcome and attrition in cognitive therapy for social phobia: results from a large multicentre trial: predictors of outcome in social phobia. Clin. Psychol. Psychother. 23 (2016), 35–46.
26. Jakubovski, E., Bloch, M.H., Prognostic subgroups for citalopram response in the STAR*D trial. J. Clin. Psychiatry 75 (2014), 738–747.
27. Kessler, R.C., Chiu, W.T., Demler, O., Merikangas, K.R., Walters, E.E., Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch. Gen. Psychiatry 62 (2005), 617–627.
28. Klumpp, H., Fitzgerald, D.A., Phan, K.L., Neural predictors and mechanisms of cognitive behavioral therapy on threat processing in social anxiety disorder. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 45 (2013), 83–91.
29. Klumpp, H., Fitzgerald, D.A., Angstadt, M., Post, D., Phan, K.L., Neural response during attentional control and emotion processing predicts improvement after cognitive behavioral therapy in generalized social anxiety disorder. Psychol. Med. 44 (2014), 3109–3121.
30. Klumpp, H., Fitzgerald, D.A., Piejko, K., Roberts, J., Kennedy, A.E., Phan, K.L., Prefrontal control and predictors of cognitive behavioral therapy response in social anxiety disorder. Soc. Cogn. Affect. Neurosci. 11 (2016), 630–640.
31. Lang, P.J., Bradley, M.M., Cuthbert, B.N., International Affective Picture System (IAPS): Affective Ratings of Pictures and Instruction Manual (Technical Report A-8). 2008, University of Florida, Gainesville, FL.
32. Ledley, D.R., Huppert, J.D., Foa, E.B., Davidson, J.R.T., Keefe, F.J., Potts, N.L.S., Impact of depressive symptoms on the treatment of generalized social anxiety disorder. Depress. Anxiety 22 (2005), 161–167.
33. Liebowitz, M.R., Social phobia. Mod. Probl. Pharmacopsychiatry 22 (1987), 141–173.
34. Loerinc, A.G., Meuret, A.E., Twohig, M.P., Rosenfield, D., Bluett, E.J., Craske, M.G., Response rates for CBT for anxiety disorders: need for standardized criteria. Clin. Psychol. Rev. 42 (2015), 72–82.
35. MacNamara, A., Rabinak, C.A., Kennedy, A.E., Fitzgerald, D.A., Liberzon, I., Stein, M.B., Phan, K.L., Emotion regulatory brain function and SSRI treatment in PTSD: neural correlates and predictors of change. Neuropsychopharmacology 41 (2016), 611–618.
36. Månsson, K.N.T., Frick, A., Boraxbekk, C.-J., Marquand, A.F., Williams, S.C.R., Carlbring, P., Andersson, G., Furmark, T., Predicting long-term outcome of internet-delivered cognitive behavior therapy for social anxiety disorder using fMRI and support vector machine learning. Transl. Psychiatry, 5, 2015, e530.
37. Mennin, D.S., Fresco, D.M., Heimberg, R.G., Schneier, F.R., Davies, S.O., Liebowitz, M.R., Screening for social anxiety disorder in the clinical setting: using the Liebowitz Social Anxiety Scale. J. Anxiety Disord. 16 (2002), 661–673.
38. Messina, I., Bianco, S., Sambin, M., Viviani, R., Executive and semantic processes in reappraisal of negative stimuli: insights from a meta-analysis of neuroimaging studies. Front. Psychol., 6, 2015.
39. Miller, E.K., Cohen, J.D., An integrative theory of prefrontal cortex function. Annu. Rev. Neurosci. 24 (2001), 167–202.
40. Moscovitch, D.A., Gavric, D.L., Senn, J.M., Santesso, D.L., Miskovic, V., Schmidt, L.A., McCabe, R.E., Antony, M.M., Changes in judgment biases and use of emotion regulation strategies during cognitive-behavioral therapy for social anxiety disorder: distinguishing treatment responders from nonresponders. Cogn. Ther. Res. 36 (2012), 261–271.
41. Mululo, S.C.C., de Menezes, G.B., Vigne, P., Fontenelle, L.F., A review on predictors of treatment outcome in social anxiety disorder. Rev. Bras. Psiquiatr. 34 (2012), 92–100 Sao Paulo Brazil. 1999.
42. Ochsner, K.N., Gross, J.J., The cognitive control of emotion. Trends Cogn. Sci. 9 (2005), 242–249.
43. Ochsner, K.N., Bunge, S.A., Gross, J.J., Gabrieli, J.D.E., Rethinking feelings: an fMRI study of the cognitive regulation of emotion. J. Cogn. Neurosci. 14 (2002), 1215–1229.
44. O'Toole, M.S., Mennin, D.S., Hougaard, E., Zachariae, R., Rosenberg, N.K., Cognitive and emotion regulation change processes in cognitive behavioural therapy for social anxiety disorder. Clin. Psychol. Psychother. 22 (2015), 667–676.
45. Petrides, M., Pandya, D.N., Dorsolateral prefrontal cortex: comparative cytoarchitectonic analysis in the human and the macaque brain and corticocortical connection patterns. Eur. J. Neurosci. 11 (1999), 1011–1036.
46. Phan, K.L., Fitzgerald, D.A., Nathan, P.J., Moore, G.J., Uhde, T.W., Tancer, M.E., Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging study. Biol. Psychiatry 57 (2005), 210–219.
47. Rabinak, C.A., MacNamara, A., Kennedy, A.E., Angstadt, M., Stein, M.B., Liberzon, I., Phan, K.L., Focal and aberrant prefrontal engagement during emotion regulation in veterans with posttraumatic stress disorder. Depress. Anxiety 31 (2014), 851–861.
48. Reinecke, A., Thilo, K., Filippini, N., Croft, A., Harmer, C.J., Predicting rapid response to cognitive-behavioural treatment for panic disorder: the role of hippocampus, insula, and dorsolateral prefrontal cortex. Behav. Res. Ther. 62 (2014), 120–128.
49. Roy-Byrne, P., Craske, M.G., Sullivan, G., Rose, R.D., Edlund, M.J., Lang, A.J., Bystritsky, A., Welch, S.S., Chavira, D.A., Golinelli, D., Campbell-Sills, L., Sherbourne, C.D., Stein, M.B., Delivery of evidence-based treatment for multiple anxiety disorders in primary care: a randomized controlled trial. JAMA 303 (2010), 1921–1928.
50. Spielberger, C.D., Manual for the State-Trait Anxiety Inventory (Form Y). 1983, Consulting Psychologists Press.
51. Spokas, M., Luterek, J.A., Heimberg, R.G., Social anxiety and emotional suppression: the mediating role of beliefs. J. Behav. Ther. Exp. Psychiatry 40 (2009), 283–291.
52. Thompson, D.G., Kesler, S.R., Sudheimer, K., Mehta, K.M., Thompson, L.W., Marquett, R.M., Holland, J.M., Reiser, R., Rasgon, N., Schatzberg, A., O'Hara, R.M., FMRI activation during executive function predicts response to cognitive behavioral therapy in older, depressed adults. Am. J. Geriatr. Psychiatry 23 (2015), 13–22.
53. van Vliet, I.M., den Boer, J.A., Westenberg, H.G., Psychopharmacological treatment of social phobia; a double blind placebo controlled study with fluvoxamine. Psychopharmacology 115 (1994), 128–134.
54. Webb, T.L., Miles, E., Sheeran, P., Dealing with feeling: a meta-analysis of the effectiveness of strategies derived from the process model of emotion regulation. Psychol. Bull. 138 (2012), 775–808.
55. Werner, K.H., Goldin, P.R., Ball, T.M., Heimberg, R.G., Gross, J.J., Assessing emotion regulation in social anxiety disorder: the emotion regulation interview. J. Psychopathol. Behav. Assess. 33 (2011), 346–354.
56. Yang, Y., Kircher, T., Straube, B., The neural correlates of cognitive behavioral therapy: recent progress in the investigation of patients with panic disorder. Behav. Res. Ther. 62 (2014), 88–96.
57. Zilverstand, A., Parvaz, M.A., Goldstein, R.Z., Neuroimaging cognitive reappraisal in clinical populations to define neural targets for enhancing emotion regulation. A Systematic Review. NeuroImage, 2016, 10.1016/j.neuroimage.2016.06.009 (Epub ahead of print).
58. Zimmerman, M., Martinez, J.H., Young, D., Chelminski, I., Dalrymple, K., Severity classification on the Hamilton depression rating scale. J. Affect. Disord. 150 (2013), 384–388.
59. Ziv, M., Goldin, P., Jazaieri, H., Hahn, K.S., Gross, J.J., Is there less to social anxiety than meets the eye? Behavioral and neural responses to three socio-emotional tasks. Biol. Mood Anxiety Disord., 3, 2013, 5.