Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids

Cell Stem Cell

Volumn 20, Issue 3, 2017, Pages 397-406.e5

  Gabriel, Elke ^a   Ramani, Anand ^a   Karow, Ulrike ^a   Gottardo, Marco ^b   Natarajan, Karthick ^a   Gooi, Li Ming ^a   Goranci Buzhala, Gladiola ^a   Krut, Oleg ^a   Peters, Franziska ^a   Nikolic, Milos ^a   Kuivanen, Suvi ^c   Korhonen, Essi ^c   Smura, Teemu ^c   Vapalahti, Olli ^c,d   Papantonis, Argyris ^a   Schmidt Chanasit, Jonas ^e,f   Riparbelli, Maria ^b   Callaini, Giuliano ^b   Krönke, Martin ^a,f,g   Utermöhlen, Olaf ^a   Gopalakrishnan, Jay ^a   more..

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF SIENA   (Italy)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^f German Center for Infection Research   (Germany)

^g UNIVERSITY OF COLOGNE   (Germany)

Author keywords

3D human brain organoids; centrosomes; cilia; microcephaly; neural progenitor cells; NPCs; premature NPC differentiation; Zika virus

Indexed keywords

AMERICAN; ARTICLE; ASIAN; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CENTROSOME; CONTROLLED STUDY; CYTOPLASM; FETUS BRAIN; HUMAN; HUMAN CELL; INDUCED PLURIPOTENT STEM CELL; MITOSIS; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SUBVENTRICULAR ZONE; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS STRAIN; ZIKA FEVER; ZIKA VIRUS; BRAIN; CYTOLOGY; ISOLATION AND PURIFICATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; ULTRASTRUCTURE; VIROLOGY;

BRAIN; CELL DIFFERENTIATION; CENTROSOME; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MITOSIS; NEURAL STEM CELLS; ORGANOIDS; ZIKA VIRUS;

EID: 85010842175     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.12.005     Document Type: Article

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