Development and characterization of new species cross-reactive anti-sialoadhesin monoclonal antibodies

Antibodies

Volumn 5, Issue 2, 2016, Pages

  De Schryver, Marjorie ^a   Van Gorp, Hanne ^b   Hoebeke, Inge ^b   De Maeyer, Bauke ^b   Ooms, Karen ^b   Pintelon, Isabel ^a   Maes, Louis J ^a   Cos, Paul ^a   Nauwynck, Hans J ^b   Delputte, Peter L ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Internalization; Monoclonal antibody; Sialoadhesin

Indexed keywords

EPITOPE; MAB 30E6; MONOCLONAL ANTIBODY; SIALOADHESIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPETITIVE BINDING ASSAY; CONTROLLED STUDY; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; FLOW CYTOMETRY; INTERNALIZATION; MAXIMUM BINDING CAPACITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

EID: 85010730938     PISSN: 20734468     EISSN: None     Source Type: Journal    
DOI: 10.3390/antib5020007     Document Type: Article

References (48)

1. Crocker, P.R.; Kelm, S.; Dubois, C.; Martin, B.; McWilliam, A.S.; Shotton, D.M.; Paulson, J.C.; Gordon, S. Purification and properties of sialoadhesin, a sialic acid-binding receptor of murine tissue macrophages. EMBO J. 1991, 10, 1661-1669. [PubMed]
2. Crocker, P.R.; Paulson, J.C.; Varki, A. Siglecs and their roles in the immune system. Nat. Rev. Immunol. 2007, 7, 255-266. [CrossRef] [PubMed]
3. Hartnell, A.; Steel, J.; Turley, H.; Jones, M.; Jackson, D.G.; Crocker, P.R. Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations. Blood 2001, 97, 288-296. [CrossRef] [PubMed]
4. Crocker, P.R.; Mucklow, S.; Bouckson, V.; McWilliam, A.; Willis, A.C.; Gordon, S.; Milon, G.; Kelm, S.; Bradfield, P. Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains. EMBO J. 1994, 13, 4490-4503. [PubMed]
5. Angata, T.; Brinkman-Van der Linden, E. I-type lectins. Biochim. Biophys. Acta 2002, 1572, 294-316. [CrossRef]
6. Vanderheijden, N.; Delputte, P.L.; Favoreel, H.W.; Vandekerckhove, J.; Van Damme, J.; vanWoensel, P.A.; Nauwynck, H.J. Involvement of sialoadhesin in entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages. J. Virol. 2003, 77, 8207-8215. [CrossRef] [PubMed]
7. Klaas, M.; Crocker, P.R. Sialoadhesin in recognition of self and non-self. Semin. Immunopathol. 2012, 34, 353-364. [CrossRef] [PubMed]
8. Varki, A.; Angata, T. Siglecs-The major subfamily of I-type lectins. Glycobiology 2006, 16, 1R-27R. [CrossRef] [PubMed]
9. Akiyama, H.; Miller, C.; Patel, H.V.; Hatch, S.C.; Archer, J.; Ramirez, N.G.; Gummuluru, S. Virus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus. J. Virol. 2014, 88, 8813-8825. [CrossRef] [PubMed]
10. Crocker, P.R.; Freeman, S.; Gordon, S.; Kelm, S. Sialoadhesin binds preferentially to cells of the granulocytic lineage. J. Clin. Investig. 1995, 95, 635-643. [CrossRef] [PubMed]
11. Crocker, P.R.; Hartnell, A.; Munday, J.; Nath, D. The potential role of sialoadhesin as a macrophage recognition molecule in health and disease. Glycoconj. J. 1997, 14, 601-609. [CrossRef] [PubMed]
12. Crocker, P.R.; Gordon, S. Isolation and characterization of resident stromal macrophages and hematopoietic cell clusters from mouse bone marrow. J. Exp. Med. 1985, 162, 993-1014. [CrossRef] [PubMed]
13. Kirchberger, S.; Majdic, O.; Steinberger, P.; Bluml, S.; Pfistershammer, K.; Zlabinger, G.; Deszcz, L.; Kuechler, E.; Knapp, W.; Stockl, J. Human rhinoviruses inhibit the accessory function of dendritic cells by inducing sialoadhesin and B7-H1 expression. J. Immunol. 2005, 175, 1145-1152. [CrossRef] [PubMed]
14. Delputte, P.L.; Nauwynck, H.J. Porcine arterivirus infection of alveolar macrophages is mediated by sialic acid on the virus. J. Virol. 2004, 78, 8094-8101. [CrossRef] [PubMed]
15. O'Neill, A.S.G.; van den Berg, T.K.; Mullen, G.E.D. Sialoadhesin-A macrophage-restricted marker of immunoregulation and inflammation. Immunology 2013, 138, 198-207. [CrossRef] [PubMed]
16. Kawasaki, N.; Vela, J.L.; Nycholat, C.M.; Rademacher, C.; Khurana, A.; van Rooijen, N.; Crocker, P.R.; Kronenberg, M.; Paulson, J.C. Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation. Proc. Natl. Acad. Sci. USA 2013, 110, 7826-7831. [CrossRef] [PubMed]
17. Barral, P.; Polzella, P.; Bruckbauer, A.; van Rooijen, N.; Besra, G.S.; Cerundolo, V.; Batista, F.D. CD169+ macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes. Nat. Immunol. 2010, 11, 303-312. [CrossRef] [PubMed]
18. Revilla, C.; Poderoso, T.; Martinez, P.; Alvarez, B.; Lopez-Fuertes, L.; Alonso, F.; Ezquerra, A.; Dominguez, J. Targeting to porcine sialoadhesin receptor improves antigen presentation to T cells. Vet. Res. 2009, 40. [CrossRef] [PubMed]
19. Junt, T.; Moseman, E.A.; Iannacone, M.; Massberg, S.; Lang, P.A.; Boes, M.; Fink, K.; Henrickson, S.E.; Shayakhmetov, D.M.; Di Paolo, N.C.; et al. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature 2007, 450, 110-114. [CrossRef] [PubMed]
20. Backer, R.; Schwandt, T.; Greuter, M.; Oosting, M.; Jungerkes, F.; Tuting, T.; Boon, L.; O'Toole, T.; Kraal, G.; Limmer, A.; et al. Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells. Proc. Natl. Acad. Sci. USA 2010, 107, 216-221. [CrossRef] [PubMed]
21. Crocker, P.R.; Redelinghuys, P. Siglecs as positive and negative regulators of the immune system. Biochem. Soc. Trans. 2008, 36, 1467-1471. [CrossRef] [PubMed]
22. Chang, Y.C.; Nizet, V. The interplay between Siglecs and sialylated pathogens. Glycobiology 2014, 24, 818-825. [CrossRef] [PubMed]
23. Heikema, A.P.; Koning, R.I.; dos Santos Rico, S.D.; Rempel, H.; Jacobs, B.C.; Endtz, H.P.; vanWamel, W.J.; Samsom, J.N. Enhanced, sialoadhesin-dependent uptake of guillain-barre syndrome-associated Campylobacter jejuni strains by human macrophages. Infect. Immun. 2013, 81, 2095-2103. [CrossRef] [PubMed]
24. Jones, C.; Virji, M.; Crocker, P.R. Recognition of sialylated meningococcal lipopolysaccharide by Siglecs expressed on myeloid cells leads to enhanced bacterial uptake. Mol. Microbiol. 2003, 49, 1213-1225. [CrossRef] [PubMed]
25. Monteiro, V.G.; Lobato, C.S.; Silva, A.R.; Medina, D.V.; de Oliveira, M.A.; Seabra, S.H.; de Souza, W.; DaMatta, R.A. Increased association of trypanosoma cruzi with sialoadhesin positive mice macrophages. Parasitol. Res. 2005, 97, 380-385. [CrossRef] [PubMed]
26. Izquierdo-Useros, N.; Lorizate, M.; Puertas, M.C.; Rodriguez-Plata, M.T.; Zangger, N.; Erikson, E.; Pino, M.; Erkizia, I.; Glass, B.; Clotet, B.; et al. Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides. PLoS Biol. 2012, 10. [CrossRef] [PubMed]
27. Van Gorp, H.; Van Breedam, W.; Delputte, P.L.; Nauwynck, H.J. The porcine reproductive and respiratory syndrome virus requires trafficking through CD163-positive early endosomes, but not late endosomes, for productive infection. Arch. Virol. 2009, 154, 1939-1943. [CrossRef] [PubMed]
28. Puryear, W.B.; Akiyama, H.; Geer, S.D.; Ramirez, N.P.; Yu, X.; Reinhard, B.M.; Gummuluru, S. Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169. PLoS Pathog. 2013, 9. [CrossRef] [PubMed]
29. Pino, M.; Erkizia, I.; Benet, S.; Erikson, E.; Fernandez-Figueras, M.T.; Guerrero, D.; Dalmau, J.; Ouchi, D.; Rausell, A.; Ciuffi, A.; et al. HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells. Retrovirology 2015, 12. [CrossRef] [PubMed]
30. Chen, W.C.; Kawasaki, N.; Nycholat, C.M.; Han, S.; Pilotte, J.; Crocker, P.R.; Paulson, J.C. Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169. PLoS ONE 2012, 7. [CrossRef] [PubMed]
31. Nycholat, C.M.; Rademacher, C.; Kawasaki, N.; Paulson, J.C. In silico-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages. J. Am. Chem. Soc. 2012, 134, 15696-15699. [CrossRef] [PubMed]
32. Carnahan, J.; Wang, P.; Kendall, R.; Chen, C.; Hu, S.; Boone, T.; Juan, T.; Talvenheimo, J.; Montestruque, S.; Sun, J.; et al. Epratuzumab, a humanized monoclonal antibody targeting CD22: Characterization of in vitro properties. Clin. Cancer Res. 2003, 9, 3982S-3990S. [PubMed]
33. Linenberger, M.L. CD33-directed therapy with gemtuzumab ozogamicin in acute myeloid leukemia: Progress in understanding cytotoxicity and potential mechanisms of drug resistance. Leukemia 2005, 19, 176-182. [CrossRef] [PubMed]
34. Akiyama, H.; Ramirez, N.G.; Gudheti, M.V.; Gummuluru, S. CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodies. PLoS Pathog. 2015, 11. [CrossRef] [PubMed]
35. Delputte, P.L.; Van Gorp, H.; Favoreel, H.W.; Hoebeke, I.; Delrue, I.; Dewerchin, H.; Verdonck, F.; Verhasselt, B.; Cox, E.; Nauwynck, H.J. Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages. PLoS ONE 2011, 6. [CrossRef] [PubMed]
36. Waldman, J.P.; Vogel, T.; Burlak, C.; Coussios, C.; Dominguez, J.; Friend, P.; Rees, M.A. Blocking porcine sialoadhesin improves extracorporeal porcine liver xenoperfusion with human blood. Xenotransplantation 2013, 20, 239-251. [CrossRef] [PubMed]
37. Brock, L.G.; Delputte, P.L.; Waldman, J.P.; Nauwynck, H.J.; Rees, M.A. Porcine sialoadhesin: A newly identified xenogeneic innate immune receptor. Am. J. Transpl. 2012, 12, 3272-3282. [CrossRef] [PubMed]
38. May, R.D.; Wheeler, H.T.; Finkelman, F.D.; Uhr, J.W.; Vitetta, E.S. Intracellular routing rather than cross-linking or rate of internalization determines the potency of immunotoxins directed against different epitopes of sIgD on murine B cells. Cell. Immunol. 1991, 135, 490-500. [CrossRef]
39. Hazin, J.; Moldenhauer, G.; Altevogt, P.; Brady, N.R. A novel method for measuring cellular antibody uptake using imaging flow cytometry reveals distinct uptake rates for two different monoclonal antibodies targeting L1. J. Immunol. Methods 2015, 423, 70-77. [CrossRef] [PubMed]
40. Van Breedam, W.; Verbeeck, M.; Christiaens, I.; Van Gorp, H.; Nauwynck, H.J. Porcine, murine and human sialoadhesin (Sn/Siglec-1/CD169): Portals for porcine reproductive and respiratory syndrome virus entry into target cells. J. Gen. Virol. 2013, 94, 1955-1960. [CrossRef] [PubMed]
41. Ducreux, J.; Tyteca, D.; Ucakar, B.; Medts, T.; Crocker, P.R.; Courtoy, P.J.; Vanbever, R. Pegylation of anti-sialoadhesin monoclonal antibodies enhances their inhibitory potencies without impairing endocytosis in mouse peritoneal macrophages. Bioconjug. Chem. 2009, 20, 295-303. [CrossRef] [PubMed]
42. Duan, X.; Nauwynck, H.J.; Favoreel, H.; Pensaert, M.B. Porcine reproductive and respiratory syndrome virus infection of alveolar macrophages can be blocked by monoclonal antibodies against cell surface antigens. Adv. Exp. Med. Biol. 1998, 440, 81-88. [PubMed]
43. van den Berg, T.K.; Breve, J.J.; Damoiseaux, J.G.; Dopp, E.A.; Kelm, S.; Crocker, P.R.; Dijkstra, C.D.; Kraal, G. Sialoadhesin on macrophages: Its identification as a lymphocyte adhesion molecule. J. Exp. Med. 1992, 176, 647-655. [CrossRef] [PubMed]
44. De La Lastra, J.M.P.; Van Den Berg, C.W.; Bullido, R.; Almazan, F.; Dominguez, J.; Llanes, D.; Morgan, B.P. Epitope mapping of 10 monoclonal antibodies against the pig analogue of human membrane cofactor protein (MCP). Immunology 1999, 96, 663-670. [CrossRef]
45. Thatte, A.; Ficarro, S.; Snapp, K.R.; Wild, M.K.; Vestweber, D.; Hunt, D.F.; Ley, K.F. Binding of function-blocking mabs to mouse and human P-selectin glycoprotein ligand-1 peptides with and without tyrosine sulfation. J. Leukoc. Biol. 2002, 72, 470-477. [PubMed]
46. Crocker, P.R.; Gordon, S. Mouse macrophage hemagglutinin (sheep erythrocyte receptor) with specificity for sialylated glycoconjugates characterized by a monoclonal antibody. J. Exp. Med. 1989, 169, 1333-1346. [CrossRef] [PubMed]
47. Delputte, P.L.; Van Breedam, W.; Delrue, I.; Oetke, C.; Crocker, P.R.; Nauwynck, H.J. Porcine arterivirus attachment to the macrophage-specific receptor sialoadhesin is dependent on the sialic acid-binding activity of the N-terminal immunoglobulin domain of sialoadhesin. J. Virol. 2007, 81, 9546-9550. [CrossRef] [PubMed]
48. Delputte, P.L.; Van Breedam, W.; Barbe, F.; Van Reeth, K.; Nauwynck, H.J. IFN-_ treatment enhances porcine arterivirus infection of monocytes via upregulation of the porcine arterivirus receptor sialoadhesin. J. Interferon Cytokine Res. 2007, 27, 757-766. [CrossRef] [PubMed]