Lipopolysaccharide and double stranded viral RNA mediate insulin resistance and increase system a amino acid transport in human trophoblast cells in vitro

Placenta

Volumn 51, Issue , 2017, Pages 18-27

  Liong, Stella ^a,b   Lappas, Martha ^a,b  

^a MERCY HOSPITAL FOR WOMEN   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Amino acid transport; Bacterial infection; Insulin resistance; Obesity; Placenta; Viral infection

Indexed keywords

AMINO ACID; AMINO ACID TRANSPORTER; BACTERIUM LIPOPOLYSACCHARIDE; DOUBLE STRANDED RNA; GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE P85 ALPHA SUBUNIT; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN KINASE B; UNCLASSIFIED DRUG; VIRUS RNA; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN; LIPOPOLYSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE;

AMINO ACID TRANSPORT; ARTICLE; CONTROLLED STUDY; CYTOTROPHOBLAST; FEMALE; GENE EXPRESSION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INSULIN RESISTANCE; ISOTOPE LABELING; NONHUMAN; PLACENTA TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TROPHOBLAST; WESTERN BLOTTING; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PREGNANCY;

AMINO ACID TRANSPORT SYSTEM A; CELLS, CULTURED; FEMALE; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; LIPOPOLYSACCHARIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; POLY I-C; PREGNANCY; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN; RNA, VIRAL; SIGNAL TRANSDUCTION; TROPHOBLASTS;

EID: 85010670183     PISSN: 01434004     EISSN: 15323102     Source Type: Journal    
DOI: 10.1016/j.placenta.2017.01.124     Document Type: Article

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