-
1
-
-
2542615200
-
Oxaliplatin fluorouracil and leucovorin as adjuvant treatment for colon cancer
-
Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators
-
André T, Boni C, Mounedji-Boudiaf L, et al; Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med. 2004;350(23):2343-2351.
-
(2004)
N Engl J Med.
, vol.350
, Issue.23
, pp. 2343-2351
-
-
André, T.1
Boni, C.2
Mounedji-Boudiaf, L.3
-
2
-
-
34250210799
-
Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: Results from NSABP C-07
-
Kuebler JP, Wieand HS, O'Connell MJ, et al. Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: results from NSABP C-07. J Clin Oncol. 2007;25(16):2198-2204.
-
(2007)
J Clin Oncol.
, vol.25
, Issue.16
, pp. 2198-2204
-
-
Kuebler, J.P.1
Wieand, H.S.2
O'Connell, M.J.3
-
3
-
-
80053384385
-
Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): An open-label, randomised, phase 3 trial
-
Fédération Francophone de Cancérologie Digestive (FFCD) 2000-05 Collaborative Group
-
Ducreux M, Malka D, Mendiboure J, et al; Fédération Francophone de Cancérologie Digestive (FFCD) 2000-05 Collaborative Group. Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): an open-label, randomised, phase 3 trial. Lancet Oncol. 2011;12(11):1032-1044.
-
(2011)
Lancet Oncol.
, vol.12
, Issue.11
, pp. 1032-1044
-
-
Ducreux, M.1
Malka, D.2
Mendiboure, J.3
-
4
-
-
0028819554
-
Age and sex are independent predictors of 5-fluorouracil toxicity: Analysis of a large scale phase III trial
-
Stein BN, Petrelli NJ, Douglass HO, Driscoll DL, Arcangeli G, Meropol NJ. Age and sex are independent predictors of 5-fluorouracil toxicity: analysis of a large scale phase III trial. Cancer. 1995; 75(1):11-17.
-
(1995)
Cancer.
, vol.75
, Issue.1
, pp. 11-17
-
-
Stein, B.N.1
Petrelli, N.J.2
Douglass, H.O.3
Driscoll, D.L.4
Arcangeli, G.5
Meropol, N.J.6
-
5
-
-
1942453306
-
Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil
-
van Kuilenburg AB. Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil. Eur J Cancer. 2004;40(7):939-950.
-
(2004)
Eur J Cancer.
, vol.40
, Issue.7
, pp. 939-950
-
-
Van Kuilenburg, A.B.1
-
6
-
-
58049196845
-
Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients
-
Gross E, Busse B, Riemenschneider M, et al. Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PLoS One. 2008;3(12):e4003.
-
(2008)
PLoS One.
, vol.3
, Issue.12
, pp. e4003
-
-
Gross, E.1
Busse, B.2
Riemenschneider, M.3
-
7
-
-
0034050905
-
Known variant DPYD alleles do not explain DPD deficiency in cancer patients
-
Collie-Duguid ES, Etienne MC, Milano G, McLeod HL. Known variant DPYD alleles do not explain DPD deficiency in cancer patients. Pharmacogenetics. 2000;10(3):217-223.
-
(2000)
Pharmacogenetics.
, vol.10
, Issue.3
, pp. 217-223
-
-
Collie-Duguid, E.S.1
Etienne, M.C.2
Milano, G.3
McLeod, H.L.4
-
8
-
-
7344249042
-
Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects
-
Ridge SA, Sludden J, Brown O, et al. Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects. Br J Clin Pharmacol. 1998;46(2):151-156.
-
(1998)
Br J Clin Pharmacol.
, vol.46
, Issue.2
, pp. 151-156
-
-
Ridge, S.A.1
Sludden, J.2
Brown, O.3
-
9
-
-
73949096486
-
Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: The FOCUS trial
-
Braun MS, Richman SD, Thompson L, et al. Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial. J Clin Oncol. 2009;27(33):5519-5528.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.33
, pp. 5519-5528
-
-
Braun, M.S.1
Richman, S.D.2
Thompson, L.3
-
10
-
-
84888012165
-
Clinical Pharmacogenetics Implementation Consortium guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing
-
Caudle KE, Thorn CF, Klein TE, et al. Clinical Pharmacogenetics Implementation Consortium guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing. Clin Pharmacol Ther. 2013;94(6):640-645.
-
(2013)
Clin Pharmacol Ther.
, vol.94
, Issue.6
, pp. 640-645
-
-
Caudle, K.E.1
Thorn, C.F.2
Klein, T.E.3
-
11
-
-
84901604087
-
Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: Investigation in the QUASAR2 study, systematic review, and meta-analysis
-
Rosmarin D, Palles C, Church D, et al. Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis. J Clin Oncol. 2014;32(10):1031-1039.
-
(2014)
J Clin Oncol.
, vol.32
, Issue.10
, pp. 1031-1039
-
-
Rosmarin, D.1
Palles, C.2
Church, D.3
-
13
-
-
84903547973
-
Oxaliplatin fluorouracil and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): An open-label randomised phase 3 trial
-
PETACC-8 Study Investigators
-
Taieb J, Tabernero J, Mini E, et al; PETACC-8 Study Investigators. Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial. Lancet Oncol. 2014;15(8):862-873.
-
(2014)
Lancet Oncol.
, vol.15
, Issue.8
, pp. 862-873
-
-
Taieb, J.1
Tabernero, J.2
Mini, E.3
-
14
-
-
84864770092
-
Association between Parkinson's disease and the HLA-DRB1 locus
-
Ahmed I, Tamouza R, DelordM, et al. Association between Parkinson's disease and the HLA-DRB1 locus. Mov Disord. 2012;27(9):1104-1110.
-
(2012)
Mov Disord.
, vol.27
, Issue.9
, pp. 1104-1110
-
-
Ahmed, I.1
Tamouza, R.2
Delord, M.3
-
15
-
-
85010677445
-
Validation of a multiplex genotyping platform using a novel genomic database approach [published online July 30, 2015]
-
Rivera-Garcia C, Bristow SL, Yarnall S, et al. Validation of a multiplex genotyping platform using a novel genomic database approach [published online July 30, 2015]. Genet Med. doi:10.1038/gim .2015.101.
-
Genet Med
-
-
Rivera-Garcia, C.1
Bristow, S.L.2
Yarnall, S.3
-
16
-
-
10044235010
-
Tag SNP selection for association studies
-
Stram DO. Tag SNP selection for association studies. Genet Epidemiol. 2004;27(4):365-374.
-
(2004)
Genet Epidemiol.
, vol.27
, Issue.4
, pp. 365-374
-
-
Stram, D.O.1
-
17
-
-
79959503826
-
-
International HapMap Consortium The International HapMap Project
-
Tanaka T; International HapMap Consortium. The International HapMap Project. Nature. 2003; 426(6968):789-796.
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 789-796
-
-
Tanaka, T.1
-
18
-
-
34648823147
-
Gatekeeping procedures with clinical trial applications
-
Dmitrienko A, Tamhane AC. Gatekeeping procedures with clinical trial applications. Pharm Stat. 2007;6(3):171-180.
-
(2007)
Pharm Stat.
, vol.6
, Issue.3
, pp. 171-180
-
-
Dmitrienko, A.1
Tamhane, A.C.2
-
19
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007;81(3):559-575.
-
(2007)
Am J Hum Genet.
, vol.81
, Issue.3
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
-
20
-
-
84961288145
-
DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147)
-
Lee AM, Shi Q, Pavey E, et al. DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147). J Natl Cancer Inst. 2014;106(12):dju298.
-
(2014)
J Natl Cancer Inst.
, vol.106
, Issue.12
, pp. dju298
-
-
Lee, A.M.1
Shi, Q.2
Pavey, E.3
-
21
-
-
84875421741
-
Phenotypic profiling of DPYD variations relevant to 5-fluorouracil sensitivity using real-time cellular analysis and in vitro measurement of enzyme activity
-
Offer SM, Wegner NJ, Fossum C, Wang K, Diasio RB. Phenotypic profiling of DPYD variations relevant to 5-fluorouracil sensitivity using real-time cellular analysis and in vitro measurement of enzyme activity. Cancer Res. 2013;73(6):1958-1968.
-
(2013)
Cancer Res.
, vol.73
, Issue.6
, pp. 1958-1968
-
-
Offer, S.M.1
Wegner, N.J.2
Fossum, C.3
Wang, K.4
Diasio, R.B.5
-
22
-
-
84879413456
-
A DPYD variant (Y186C) in individuals of African ancestry is associated with reduced DPD enzyme activity
-
Offer SM, Lee AM, Mattison LK, Fossum C, Wegner NJ, Diasio RB. A DPYD variant (Y186C) in individuals of African ancestry is associated with reduced DPD enzyme activity. Clin Pharmacol Ther. 2013;94(1):158-166.
-
(2013)
Clin Pharmacol Ther.
, vol.94
, Issue.1
, pp. 158-166
-
-
Offer, S.M.1
Lee, A.M.2
Mattison, L.K.3
Fossum, C.4
Wegner, N.J.5
Diasio, R.B.6
-
23
-
-
67349223302
-
Influence of dihydropyrimidine dehydrogenase gene (DPYD) coding sequence variants on the development of fluoropyrimidine-related toxicity in patients with high-grade toxicity and patients with excellent tolerance of fluoropyrimidine-based chemotherapy
-
Kleibl Z, Fidlerova J, Kleiblova P, et al. Influence of dihydropyrimidine dehydrogenase gene (DPYD) coding sequence variants on the development of fluoropyrimidine-related toxicity in patients with high-grade toxicity and patients with excellent tolerance of fluoropyrimidine-based chemotherapy. Neoplasma. 2009;56(4):303-316.
-
(2009)
Neoplasma.
, vol.56
, Issue.4
, pp. 303-316
-
-
Kleibl, Z.1
Fidlerova, J.2
Kleiblova, P.3
-
24
-
-
69049114190
-
Dihydropyrimidine dehydrogenase gene variation and severe 5-fluorouracil toxicity: A haplotype assessment
-
Amstutz U, Farese S, Aebi S, Largiadèr CR. Dihydropyrimidine dehydrogenase gene variation and severe 5-fluorouracil toxicity: a haplotype assessment. Pharmacogenomics. 2009;10(6):931-944.
-
(2009)
Pharmacogenomics.
, vol.10
, Issue.6
, pp. 931-944
-
-
Amstutz, U.1
Farese, S.2
Aebi, S.3
Largiadèr, C.R.4
-
25
-
-
43749114271
-
Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: A prospective clinical trial by the German 5-FU Toxicity Study Group
-
German 5-FU Toxicity Study Group
-
SchwabM, Zanger UM, Marx C, et al; German 5-FU Toxicity Study Group. Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group. J Clin Oncol. 2008;26(13):2131-2138.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.13
, pp. 2131-2138
-
-
Schwab, M.1
Zanger, U.M.2
Marx, C.3
-
26
-
-
79955998006
-
Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer
-
Deenen MJ, Tol J, Burylo AM, et al. Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer. Clin Cancer Res. 2011;17(10):3455-3468.
-
(2011)
Clin Cancer Res.
, vol.17
, Issue.10
, pp. 3455-3468
-
-
Deenen, M.J.1
Tol, J.2
Burylo, A.M.3
-
27
-
-
84921280613
-
Influence of DPYD genetic polymorphisms on 5-fluorouracil toxicities in patients with colorectal cancer: Ameta-analysis
-
Li Q, Liu Y, Zhang HM, et al. Influence of DPYD genetic polymorphisms on 5-fluorouracil toxicities in patients with colorectal cancer: ameta-analysis. Gastroenterol Res Pract. 2014;2014:827989.
-
(2014)
Gastroenterol Res Pract.
, vol.2014
, pp. 827989
-
-
Li, Q.1
Liu, Y.2
Zhang, H.M.3
-
28
-
-
84878247061
-
Pharmacogenomics in colorectal cancer: A genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration
-
EPICOLON Consortium
-
Fernandez-Rozadilla C, Cazier JB, Moreno V, et al; EPICOLON Consortium. Pharmacogenomics in colorectal cancer: a genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration. Pharmacogenomics J. 2013;13(3): 209-217.
-
(2013)
Pharmacogenomics J.
, vol.13
, Issue.3
, pp. 209-217
-
-
Fernandez-Rozadilla, C.1
Cazier, J.B.2
Moreno, V.3
-
29
-
-
84861329544
-
Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients
-
Won HH, Lee J, Park JO, et al. Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients. Cancer. 2012;118(11):2828-2836.
-
(2012)
Cancer.
, vol.118
, Issue.11
, pp. 2828-2836
-
-
Won, H.H.1
Lee, J.2
Park, J.O.3
|