Blocking of platelet glycoprotein receptor Ib reduces "thrombo-inflammation" in mice with acute ischemic stroke

Journal of Neuroinflammation

Volumn 14, Issue 1, 2017, Pages

  Schuhmann, Michael K ^a   Guthmann, Josua ^a   Stoll, Guido ^a   Nieswandt, Bernhard ^c   Kraft, Peter ^a   Kleinschnitz, Christoph ^a,b  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Glycoprotein receptor Ib; Ischemic stroke; Thrombo inflammation; Transient middle cerebral artery occlusion

Indexed keywords

ANTIGEN BINDING FRAGMENT; GLYCOPROTEIN RECEPTOR IB; INTERLEUKIN 1BETA; INTERLEUKIN 6; RECEPTOR; RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; THROMBIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HEMORRHAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL ACTIVATION; CELL INFILTRATION; CEREBRAL MICROVASCULATURE; CLINICAL OUTCOME; CONTROLLED STUDY; FUNCTIONAL DISEASE; INFLAMMATION; MACROPHAGE; MALE; MICROGLIA; MICROVASCULATURE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR BLOCKING; RISK; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THROMBO INFLAMMATION; ANIMAL; C57BL MOUSE; CEREBROVASCULAR ACCIDENT; METABOLISM; PATHOLOGY; THROMBOSIS;

ANIMALS; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; STROKE; THROMBOSIS;

EID: 85009986024     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-017-0792-y     Document Type: Article

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