DNA array analysis of gene expression changes by Chotosan in the ischemic rat brain

Journal of Traditional Medicines

Volumn 21, Issue 4, 2004, Pages 182-186

  Tohda, Michihisa ^a   Matsumoto, Kinzo ^a   Hayashi, Hisae ^a   Murakami, Yukihisa ^a   Watanabe, Hiroshi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Choto san; dementia; DNA microarray; gene expression; ischemia; rat brain

Indexed keywords

EID: 85009593017     PISSN: 18801447     EISSN: 18813747     Source Type: Journal    
DOI: 10.11339/jtm.21.182     Document Type: Article

References (17)

1. Terasawa, K., Shimada, Y., Kita, T., Yamamoto, T., Tosa, H., Tanaka, N., Saito, Y., Kanaki, E., Goto, S., Mizushima, N., Fujioka, M., Takase, S., Seki, H., Kimura, I., Ogawa, T., Nakamura, S., Araki, G., Maruyama, I., Maruyama, Y., Takaori, S.: Choto-san in the treatment of vascular dementia: a double-blind, placebo controlled study. Phytomedicine. 4, 15-22, 1997.
2. Egashira, N., Iwasaki, K., Ueki, S., Kurauchi, K. and Fujiwara, M. : Choto-san and Yoku-kan-san-ka-chimpi-hange improve the disruption of spatial cognition in rats. J. Traditional Medicines, 10, 190-194, 1993 (Article in Japanese, Abstract in English).
3. Zhang, S., Murakami, Y., Tohda, M., Matsumoto, K., Sakakibara, I., Takayama, H., Aimi, N. and Watanabe, H.: Protective effect of Choto-san, Chotoko and its alkaloids on experimental vascular dementia in mice: Elucidation using Morris water maze test. J. Traditional Medicines, 19, 28-36, 2002 (Article in Japanese, Abstract in English).
4. Mizushima, Y., Kan, S., Yoshida, S., Irie, Y., Urata, Y.: Effect of Choto-san, a Kampo medicine, on impairment of passive avoidance performance in senescence accelerated mouse (SAM). Phytother Res. 17 (5), 542-545, 2003.
5. Dohi, K., Satoh, K., Ikeda, Y., Ohtaki, H., Shioda, S., Aruga, T.: Neuroprotective effect from ischemia and direct free radical scavenging activity of Choto-san (kampo medicine). Acta Neurochir Suppl. 86, 123-127, 2003.
6. Sekiya, N., Shimada, Y., Shibahara, N., Takagi, S., Yokoyama, K., Kasahara, Y., Sakakibara, I., Terasawa, K.: Inhibitory effects of Choto-san (Diao-teng-san), and hooks and stems of Uncaria sinensis on free radical-induced lysis of rat red blood cells. Phytomedicine. 9(7), 636-640, 2002.
7. Mahakunakorn, P., Tohda, M., Murakami, Y., Matsumoto, K. and Watanabe, H.: Antioxidant and free radical scavenging activity of Choto-san and its related constituents. Biol. Pharm. Bull., 27, 38-46, 2004.
8. Sugimoto, A., Goto, K., Ishige, A., Komatsu, Y., Miyamoto, K.I.: Effect of Choto-san, a Kampo medicine, on the cerebral blood flow autoregulation in spontaneously hypertensive rats. Jpn J Pharmacol. 83 (2), 135-142, 2000.
9. Murakami, Y., Tanaka, E., Sakai, Y., Matsumoto, K., Li, H.-B., Watanabe, H.: Tacrine improves working memory deficit caused by permanent occlusion of bilateral common carotid arteries in rats. Jpn. J. Pharmacol. 75, 443-446, 1997.
10. Ni, J.-W., Ohta, H., Matsumoto, K., Watanabe, H.: Progressive cognitive impairment following chronic cerebral hypoperfusion induced by permanent occlusion bilateral carotid arteries in rat. Brain Res. 653, 231-236, 1994.
11. Ni, J.-W., Matsumoto, K., Li, H.-B., Murakami, Y., Watanabe, H.: Neuronal damage and decrease of central acetylcholine level following permanent occlusion od bilateral carotid arteries in rat. Brain Res. 673, 290-296, 1995.
12. Nanri, M., Miyake, H., Murakami, Y., Matsumoto, K., Watanabe, H.: Chronic cerebral hypoperfusion-induced neuropathological changes in rats. Jpn. J. Psychopharmacol. 18, 181-188, 1998.
13. Breteler, M.M.B., van Swieten, J.C., Bots, M.L., Grobbee, D.E., Claus, J.J., van den Hout, J.H.W., van Harskamp, F., Tanghe, H.L.J., de Jong, P.T.V.M., van Gijn, J., Hofman, A.: Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: the Rotterdam Study. Neurology, 44, 1246-1252, 1994.
14. Brun, A., Englund, E.: A white matter disorder in dementia of the Alzheimer type: A pathoanatomical study. Ann Neurol., 19, 253-262, 1986.
15. Tohda, M., Suwanakitch, P., Jeenapongsa, R., Hayashi, H., Watanabe, H.: Expression Changes of the mRNA of Alzheimer's Disease Related Factors in the Permanent Ischemic Rat Brain, submitted for publication.
16. Chomczynski, P., Sacchi, N.: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159, 1987.
17. Doyle, J.L., DeSilva, U., Miller, W. and Green, E.D. : Divergent human and mouse orthologs of a novel gene (WBSCR15/Wbscr15) reside within the genomic interval commonly deleted in Williams syndrome. Cytogenet. Cell Genet. 90 (3-4), 285-290, 2000.