Comparison of risk scoring systems for patients presenting with upper gastrointestinal bleeding: International multicentre prospective study

BMJ (Online)

Volumn 356, Issue , 2017, Pages

  Stanley, Adrian J ^a   Laine, Loren ^b   Dalton, Harry R ^c   Ngu, Jing H ^d   Schultz, Michael ^e,g   Abazi, Roseta ^f   Zakko, Liam ^b   Thornton, Susan ^a   Wilkinson, Kelly ^c   Khor, Cristopher J L ^d   Murray, Iain A ^c   Laursen, Stig B ^f  

^a GLASGOW ROYAL INFIRMARY   (United Kingdom)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ROYAL CORNWALL HOSPITAL   (United Kingdom)

^d SINGAPORE GENERAL HOSPITAL   (Singapore)

^e UNIVERSITY OF OTAGO   (New Zealand)

^f ODENSE UNIVERSITY HOSPITAL   (Denmark)

^g DUNEDIN HOSPITAL   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ADULT; AGED; AIMS65 SCORE; ARTICLE; ASIA; BLOOD TRANSFUSION; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIGESTIVE SYSTEM DISEASE ASSESSMENT; ENDOSCOPIC THERAPY; EUROPE; FEMALE; GLASGOW BLATCHFORD SCORE; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY RATE; MULTICENTER STUDY; NORTH AMERICA; OUTCOME ASSESSMENT; PACIFIC ISLANDS; PNED SCORE; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECURRENT DISEASE; RISK ASSESSMENT; RISK FACTOR; ROCKALL SCORE; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SURVIVAL RATE; UPPER GASTROINTESTINAL BLEEDING; AREA UNDER THE CURVE; CLINICAL TRIAL; GASTROINTESTINAL HEMORRHAGE; MIDDLE AGED; MORTALITY; PREDICTIVE VALUE; PROCEDURES; PROGNOSIS; RECEIVER OPERATING CHARACTERISTIC; SEVERITY OF ILLNESS INDEX; STATISTICS AND NUMERICAL DATA; UPPER GASTROINTESTINAL TRACT; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; RISK ASSESSMENT; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; UPPER GASTROINTESTINAL TRACT; YOUNG ADULT;

EID: 85009070752     PISSN: 09598146     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.i6432     Document Type: Article

References (34)

1. Rockall TA, Logan RFA, Devlin HB, Northfield TC. Incidence of and mortality from acute upper gastrointestinal haemorrhage in the UK. BMJ 1995;311:222-6. doi:10.1136/bmj.311.6999.222
2. Blatchford O, Davidson LA, Murray WR, Blatchford M, Pell J. Acute upper gastrointestinal haemorrhage in west of Scotland: case ascertainment study. BMJ 1997;315:510-4. doi: 10.1136/bmj.315.7107.510
3. Hearnshaw SA, Logan RFA, Lowe D, Travis SP, Murphy MF, Palmer KR. Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in the 2007 UK audit. Gut 2011;60:1327-35. doi:10.1136/gut.2010.228437
4. Rockall TA, Logan RFA, Devlin HB, Northfield TC. Risk assessment after acute upper gastrointestinal haemorrhage. Gut 1996;38:316-21. doi:10.1136/gut.38.3.316
5. Marmo R, Koch M, Cipolletta L, et al. Italian registry on upper gastrointestinal bleeding (Progetto Nazionale Emorragie Digestive-PNED 2). Predicting mortality in non-variceal upper gastrointestinal bleeders: validation of the Italian PNED Score and Prospective Comparison with the Rockall Score. Am J Gastroenterol 2010;105:1284-91. doi:10.1038/ajg.2009.687
6. Saeed ZA, Winchester CB, Carolyn B, Michaeletz PA, Woods KL, Graham DY. A scoring system to predict rebleeding after endoscopic therapy of non-variceal upper gastrointestinal hemorrhage. Am J Gastroenterol 1993;88:1842-9
7. Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper gastrointestinal haemorrhage. Lancet 2000;356:1318-21. doi:10.1016/S0140-6736(00)02816-6
8. Saltzman JR, Tabak YP, Hyett BH, Sun X, Travis AC, Johannes RS. A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding. Gastrointest Endosc 2011;74:1215-24. doi:10.1016/j.gie.2011.06.024
9. Das A, Ben-Menachem T, Farooq FT, et al. Artificial neural network as a predictive instrument in patients with acute nonvariceal upper gastrointestinal hemorrhage. Gastroenterology 2008;134:65-74. doi:10.1053/j.gastro.2007.10.037
10. Laursen SB, Hansen JM, Schaffalitzky de Muckadell OB. The Glasgow Blatchford score is the most accurate assessment of patients with upper gastrointestinal hemorrhage. Clin Gastroenterol Hepatol 2012;10:1130-1135.e1. doi:10.1016/j.cgh.2012.06.022
11. Hearnshaw SA, Logan RFA, Lowe D, Travis SPL, Murphy MF, Palmer KR. Use of endoscopy for management of acute upper gastrointestinal bleeding in the UK: results of a nationwide audit. Gut 2010;59:1022 doi:10.1136/gut.2008.174599
12. Stanley AJ, Ashley D, Dalton HR, et al. Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation. Lancet 2009;373:42-7. doi:10.1016/S0140-6736(08)61769-9
13. Laursen SB, Dalton HR, Murray IA, et al. Upper Gastrointestinal Hemorrhage International Consortium Upper Gastrointestinal Hemorrhage International Consortium. Performance of new thresholds of the Glasgow Blatchford score in managing patients with upper gastrointestinal bleeding. Clin Gastroenterol Hepatol 2015;13:115-21.e2. doi:10.1016/j.cgh.2014.07.023
14. McLaughlin C, Vine L, Chapman L, et al. The management of low-risk primary upper gastrointestinal haemorrhage in the community: a 5-year observational study. Eur J Gastroenterol Hepatol 2012;24:288-93. doi:10.1097/MEG.0b013e32834febef
15. Lim LG, Ho KY, Chan YH, et al. Urgent endoscopy is associated with lower mortality in high-risk but not low-risk nonvariceal upper gastrointestinal bleeding. Endoscopy 2011;43:300-6. doi:10.1055/s-0030-1256110
16. Hyett BH, Abougergi MS, Charpentier JP, et al. The AIMS65 score compared with the Glasgow-Blatchford score in predicting outcomes in upper GI bleeding. Gastrointest Endosc 2013;77:551-7. doi:10.1016/j.gie.2012.11.022
17. Stanley AJ, Dalton HR, Blatchford O, et al. Multicentre comparison of the Glasgow Blatchford and Rockall Scores in the prediction of clinical end-points after upper gastrointestinal haemorrhage. Aliment Pharmacol Ther 2011;34:470-5. doi:10.1111/j.1365-2036.2011.04747.x
18. Pang SH, Ching JY, Lau JYW, Sung JJY, Graham DY, Chan FKL. Comparing the Blatchford and pre-endoscopic Rockall score in predicting the need for endoscopic therapy in patients with upper GI hemorrhage. Gastrointest Endosc 2010;71:1134-40. doi:10.1016/j. gie.2010.01.028
19. Yaka E, Ylmaz S, Doan NÖ, Pekdemir M. Comparison of the Glasgow-Blatchford and AIMS65 scoring systems for risk stratification in upper gastrointestinal bleeding in the emergency department. Acad Emerg Med 2015;22:22-30. doi:10.1111/acem.12554
20. Barkun AN, Bardou M, Kuipers EJ, et al. International Consensus Upper Gastrointestinal Bleeding Conference Group. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med 2010;152:101-13. doi:10.7326/0003-4819-152-2-201001190-00009
21. National Institute for Health and Clinical Excellence. Acute Upper Gastrointestinal Bleeding: management. Clinical Guideline 141.NICE, 2012
22. Gralnek IM, Dumonceau JM, Kuipers EJ, et al. Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2015;47:a1-46. doi:10.1055/s-0034-1393172
23. Laine L, Jensen DM. Management of patients with ulcer bleeding. Am J Gastroenterol 2012;107:345-60, quiz 361. doi:10.1038/ajg.2011.480
24. de Franchis R. Baveno V Faculty. Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol 2010;53:762-8. doi:10.1016/j.jhep.2010.06.004
25. Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013;368:11-21. doi:10.1056/NEJMoa1211801
26. Laine L, Spiegel B, Rostom A, et al. Methodology for randomized trials of patients with nonvariceal upper gastrointestinal bleeding: recommendations from an international consensus conference. Am J Gastroenterol 2010;105:540-50. doi:10.1038/ajg.2009.702
27. DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1988;44:837-45. doi:10.2307/2531595
28. Youden WJ. Index for rating diagnostic tests. Cancer 1950;3:32-5. doi:10.1002/1097-0142(1950)3:1<32::AIDCNCR2820030106> 3.0.CO;2-3
29. Abougergi MS, Charpentier JP, Bethea E, et al. A prospective multicentre study of the AIMS65 score compared with the Glasgow Blatchford score in predicting upper gastrointestinal hemorrhage outcomes. J Clin Gastroenterol 2016;50:464-9. doi:10.1097/MCG.0000000000000395
30. Palmer AJ, Moroni F, McLeish S, et al. P0440 A comparison of the Glasgow Blatchford and AIMS65 scores in predicting need for clinical intervention and mortality in acute non-variceal upper GI bleeds: a retrospective cohort study. United European Gastroenterol J 2014;2(Suppl):A132-605. doi:10.1177/2050640614548980
31. Robertson M, Majumdar A, Boyapati R, et al. Risk stratification in acute upper GI bleeding: comparison of the AIMS65 score with the Glasgow-Blatchford and Rockall scoring systems. Gastrointest Endosc 2016;83:1151-60. doi:10.1016/j.gie.2015.10.021
32. Lim WS, van der Eerden MM, Laing R, et al. Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax 2003;58:377-82. doi:10.1136/thorax.58.5.377
33. Aujesky D, Roy PM, Verschuren F, et al. Outpatient versus inpatient treatment for patients with acute pulmonary embolism: an international, open-label, randomised, non-inferiority trial. Lancet 2011;378:41-8. doi:10.1016/S0140-6736(11)60824-6
34. Campbell HE, Stokes EA, Bargo D, et alCosts and quality of life associated with acute upper gastrointestinal bleeding in the UK: cohort analysis of patients in a cluster randomised trial. BMJ Open 2015;5:e007230doi:10.1136/bmjopen-2014-007230