Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management

Kidney International

Volumn 91, Issue 2, 2017, Pages 423-434

  Bridoux, Frank ^a,b   Javaugue, Vincent ^a   Bender, Sébastien ^b   Leroy, Fannie ^a   Aucouturier, Pierre ^c   Debiais Delpech, Céline ^a   Goujon, Jean Michel ^a   Quellard, Nathalie ^a   Bonaud, Amélie ^b   Clavel, Marie ^b   Trouillas, Patrick ^d,e   Di Meo, Florent ^d   Gombert, Jean Marc ^a   Fermand, Jean Paul ^f   Jaccard, Arnaud ^g   Cogné, Michel ^b   Touchard, Guy ^a   Sirac, Christophe ^b  

^a POITIERS UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY OF LIMOGES   (France)

^c CENTRE DE RECHERCHE SAINT ANTOINE   (France)

^d Univ Limoges   (France)

^e PALACKÝ UNIVERSITY   (Czech Republic)

^f SAINT LOUIS HOSPITAL   (France)

^g LIMOGES UNIVERSITY HOSPITAL   (France)

Author keywords

free light chains; glomerulosclerosis; immunoglobulin heavy chains; monoclonal gammopathy

Indexed keywords

BORTEZOMIB; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; MELPHALAN; CHA HEAVY CHAIN DISEASE PROTEIN, HUMAN; HEAVY CHAIN DISEASE PROTEINS, HUMAN; IMMUNOGLOBULIN HEAVY CHAIN;

ADULT; AGED; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BONE MARROW; BONE MARROW CELL; CHEMOTHERAPY; CHRONIC KIDNEY FAILURE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MEGADOSE; EARLY DIAGNOSIS; FEMALE; GENE DELETION; GENE SEQUENCE; GLOMERULOSCLEROSIS; HEAVY CHAIN; HEAVY CHAIN DEPOSITION DISEASE; HEAVY CHAIN DISEASE; HEMATOLOGICAL PARAMETERS; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPATHOGENESIS; IMMUNOPROLIFERATIVE SMALL INTESTINAL DISEASE; ISOELECTRIC POINT; KIDNEY INJURY; KIDNEY TUBULE PRESSURE; LIGHT CHAIN; MALE; MONOCLONAL IMMUNOGLOBULINEMIA; MYELOMA; NEPHROTIC SYNDROME; NEPHROTOXICITY; OUTCOME VARIABLE; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN ELECTROPHORESIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; BIOPSY; CLINICAL TRIAL; COMBINATION DRUG THERAPY; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; FRANCE; GENETICS; GLOMERULONEPHRITIS; IMMUNOLOGY; KIDNEY; KIDNEY DISEASES; MIDDLE AGED; MULTICENTER STUDY; PARAPROTEINEMIAS; PATHOLOGY; POLYMERASE CHAIN REACTION; RENAL INSUFFICIENCY, CHRONIC; TREATMENT OUTCOME; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BIOPSY; BORTEZOMIB; DRUG THERAPY, COMBINATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FRANCE; GLOMERULONEPHRITIS; HEAVY CHAIN DISEASE; HUMANS; IMMUNOGLOBULIN ALPHA-CHAINS; IMMUNOGLOBULIN GAMMA-CHAINS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; KIDNEY; KIDNEY DISEASES; MALE; MIDDLE AGED; NEPHROTIC SYNDROME; PARAPROTEINEMIAS; POLYMERASE CHAIN REACTION; RENAL INSUFFICIENCY, CHRONIC; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 85008950192     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2016.09.004     Document Type: Article

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