DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218

Biological Psychiatry

Volumn 81, Issue 4, 2017, Pages 306-315

  Torres Berrío, Angélica ^a,d   Lopez, Juan Pablo ^e,f   Bagot, Rosemary C ^b   Nouel, Dominique ^d   Dal Bo, Gregory ^d,g   Cuesta, Santiago ^c,d   Zhu, Lei ^d   Manitt, Colleen ^d   Eng, Conrad ^d   Cooper, Helen M ^h   Storch, Kai Florian ^c,d   Turecki, Gustavo ^c,d,f   Nestler, Eric J ⁱ   Flores, Cecilia ^c,d  

^a McGill Program in NeuroEngineering   (Canada)

^b Psychology Department   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

^e Department of Human Genetics ^*  (Canada)

^f MCGILL UNIVERSITY   (Canada)

^g IRBA   (France)

^h UNIVERSITY OF QUEENSLAND   (Australia)

ⁱ MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic social defeat stress; Guidance cue; Major depressive disorder; microRNA; Neurodevelopment; Resilience

Indexed keywords

DELETED IN COLORECTAL CANCER RECEPTOR; MICRORNA; MICRORNA 218; RECEPTOR; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; DCC PROTEIN, HUMAN; MESSENGER RNA; MIRN218 MICRORNA, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ADULT; ANHEDONIA; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN TISSUE; CHRONIC STRESS; CONTROLLED STUDY; DEPRESSION; DISEASE PREDISPOSITION; DOPAMINERGIC NERVE CELL; GENE CONTROL; GENE EXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; IN VITRO STUDY; MAJOR DEPRESSION; MALE; MOUSE; NEUROBLASTOMA CELL LINE; NONHUMAN; PHENOTYPE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOCIAL INTERACTION TEST; SUDDEN DEATH; SUICIDE; UPREGULATION; ANIMAL; C57BL MOUSE; COMPLICATION; DEPRESSIVE DISORDER, MAJOR; MENTAL STRESS; METABOLISM; SOCIAL BEHAVIOR; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; DEPRESSIVE DISORDER, MAJOR; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; PREFRONTAL CORTEX; PYRAMIDAL CELLS; RECEPTORS, CELL SURFACE; RNA, MESSENGER; SOCIAL BEHAVIOR; STRESS, PSYCHOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 85008931784     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2016.08.017     Document Type: Article

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