Attenuation of tumor growth by honokiol: An evolving role in oncology

Drug Discoveries & Therapeutics

Volumn 6, Issue 6, 2011, Pages 327-328

  Kapoor, Shailendra ^a  

^a NONE   (United States)

Author keywords

cancer; Honokiol; STAT3; tumor

Indexed keywords

EID: 85008735989     PISSN: 18817831     EISSN: 1881784X     Source Type: Journal    
DOI: 10.5582/ddt.2012.v6.6.327     Document Type: Article

References (9)

1. Guillermo RF, Chilampalli C, Zhang X, Zeman D, Fahmy H, Dwivedi C. Time and dose-response effects of honokiol on UVB-induced skin cancer development. Drug Discov Ther. 2012; 6:140-146.
2. Nagalingam A, Arbiser JL, Bonner MY, Saxena NK, Sharma D. Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis. Breast Cancer Res. 2012; 14: R35.
3. Singh T, Katiyar SK. Honokiol, a phytochemical from Magnolia spp., inhibits breast cancer cell migration by targeting nitric oxide and cyclooxygenase-2. Int J Oncol. 2011; 38:769-776.
4. Liu H, Zang C, Emde A. Antitumor effect of honokiol alone and in combination with other anticancer agents in breast cancer. Eur J Pharmacol. 2008; 591:43-51.
5. Liu SH, Wang KB, Lan KH. Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu mice. PLoS One. 2012; 7:e43711.
6. Sheu ML, Liu SH, Lan KH. Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth. PLoS One. 2007; 2:e1096.
7. Ponnurangam S, Mammen JM, Ramalingam S. Honokiol in combination with radiation targets notch signaling to inhibit colon cancer stem cells. Mol Cancer Ther. 2012; 11:963-972.
8. He Z, Subramaniam D, Ramalingam S. Honokiol radiosensitizes colorectal cancer cells: Enhanced activity in cells with mismatch repair defects. Am J Physiol Gastrointest Liver Physiol. 2011; 301:G929-G937.
9. Arora S, Bhardwaj A, Srivastava SK. Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells. PLoS One. 2011; 6:e21573.