Investigation of the microbiota of the reproductive tract in women undergoing a total hysterectomy and bilateral salpingo-oopherectomy

Fertility and Sterility

Volumn 107, Issue 3, 2017, Pages 813-820.e1

  Miles, Shana M ^a,b   Hardy, Britney L ^b   Merrell, D Scott ^b  

^a WALTER REED ARMY MEDICAL CENTER   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

fallopian tube microbiota; ovarian microbiota; Reproductive tract microbiota; salpingitis; upper genital tract colonization

Indexed keywords

RNA 16S;

ADULT; ARTICLE; BILATERAL SALPINGO OOPHERECTOMY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FEMALE GENITAL SYSTEM; FIRMICUTES; GENE AMPLIFICATION; GYNECOLOGIC SURGERY; HIGH THROUGHPUT SEQUENCING; HUMAN; HYSTERECTOMY; LACTOBACILLUS; MICROBIAL COMMUNITY; MIDDLE AGED; PILOT STUDY; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; TERTIARY HEALTH CARE; UTERINE CERVIX DYSPLASIA; VAGINA FLORA; BACTERIUM; CLASSIFICATION; COMPARATIVE STUDY; FALLOPIAN TUBE; GENETICS; ISOLATION AND PURIFICATION; MARYLAND; MICROBIOLOGY; OVARIECTOMY; OVARY; PUBLIC HOSPITAL; RIBOTYPING; SALPINGECTOMY; SURGERY; UTERUS;

ADULT; BACTERIA; FALLOPIAN TUBES; FEMALE; HOSPITALS, MILITARY; HUMANS; HYSTERECTOMY; MARYLAND; MIDDLE AGED; OVARIECTOMY; OVARY; PILOT PROJECTS; PROSPECTIVE STUDIES; RIBOTYPING; SALPINGECTOMY; UTERUS;

EID: 85008689634     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2016.11.028     Document Type: Article

References (34)

1. 1 Ordovas, J.M., Mooser, V., Metagenomics: the role of the microbiome in cardiovascular diseases. Curr Opin Lipidol 17 (2006), 157–161.
2. 2 Scales, B.S., Huffnagle, G.B., The microbiome in wound repair and tissue fibrosis. J Pathol 229 (2013), 323–331.
3. 3 Russell, S.L., Finlay, B.B., The impact of gut microbes in allergic diseases. Curr Opin Gastroenterol 28 (2012), 563–569.
4. 4 Catrina, A.I., Deane, K.D., Scher, J.U., Gene, environment, microbiome and mucosal immune tolerance in rheumatoid arthritis. Rheumatology 55 (2016), 391–402.
5. 5 Kinross, J.M., Darzi, A.W., Nicholson, J.K., Gut microbiome-host interactions in health and disease. Genome Med, 3, 2011, 14.
6. 6 Zhou, X., Brown, C.J., Abdo, Z., Davis, C.C., Hansmann, M.A., Joyce, P., et al. Differences in the composition of vaginal microbial communities found in healthy Caucasian and black women. ISME J 1 (2007), 121–133.
7. 7 Hickey, R.J., Abdo, Z., Zhou, X., Nemeth, K., Hansmann, M., Osborn, T.W., et al. Effects of tampons and menses on the composition and diversity of vaginal microbial communities over time. Br J Obstet Gynecol 120 (2013), 695–704 discussion 706.
8. 8 Hickey, R.J., Zhou, X., Settles, M.L., Erb, J., Malone, K., Hansmann, M.A., et al. Vaginal microbiota of adolescent girls prior to the onset of menarche resemble those of reproductive-age women. MBio 6 (2015), e00097–e00115.
9. 9 Yamamoto, T., Zhou, X., Williams, C.J., Hochwalt, A., Forney, L.J., Bacterial populations in the vaginas of healthy adolescent women. J Pediatr Adolesc Gynecol 22 (2009), 11–18.
10. 10 Brotman, R.M., Shardell, M.D., Gajer, P., Fadrosh, D., Chang, K., Silver, M.I., et al. Association between the vaginal microbiota, menopause status, and signs of vulvovaginal atrophy. Menopause 21 (2014), 450–458.
11. 11 Smith, B.C., McAndrew, T., Chen, Z., Harari, A., Barris, D.M., Viswanathan, S., et al. The cervical microbiome over 7 years and a comparison of methodologies for its characterization. PLoS One, 7, 2012, e40425.
12. 12 Fettweis, J.M., Serrano, M.G., Sheth, N.U., Mayer, C.M., Glascock, A.L., Brooks, J.P., et al. Species-level classification of the vaginal microbiome. BMC Genomics, 13(Suppl 8), 2012, S17.
13. 13 Hyman, R.W., Herndon, C.N., Jiang, H., Palm, C., Fukushima, M., Bernstein, D., et al. The dynamics of the vaginal microbiome during infertility therapy with in vitro fertilization-embryo transfer. J Assist Reprod Genet 29 (2012), 105–115.
14. 14 Aagaard, K., Riehle, K., Ma, J., Segata, N., Mistretta, T.A., Coarfa, C., et al. A metagenomic approach to characterization of the vaginal microbiome signature in pregnancy. PLoS One, 7, 2012, e36466.
15. 15 Mitchell, C.M., Haick, A., Nkwopara, E., Garcia, R., Rendi, M., Agnew, K., et al. Colonization of the upper genital tract by vaginal bacterial species in nonpregnant women. Am J Obstet Gynecol 212 (2015), 611.e1–611.e9.
16. 16 George, S.H., Garcia, R., Slomovitz, B.M., Ovarian cancer: the fallopian tube as the site of origin and opportunities for prevention. Front Oncol, 6, 2016, 108.
17. 17 Strandell, A., Lindhard, A., Why does hydrosalpinx reduce fertility? The importance of hydrosalpinx fluid. Hum Reprod 17 (2002), 1141–1145.
18. 18 Meyer, W.R., Castelbaum, A.J., Somkuti, S., Sagoskin, A.W., Doyle, M., Harris, J.E., et al. Hydrosalpinges adversely affect markers of endometrial receptivity. Hum Reprod 12 (1997), 1393–1398.
19. 19 Ng, E.H., Ajonuma, L.C., Lau, E.Y., Yeung, W.S., Ho, P.C., Adverse effects of hydrosalpinx fluid on sperm motility and survival. Hum Reprod 15 (2000), 772–777.
20. 20 Wang, Y., Qian, P.Y., Conservative fragments in bacterial 16S rRNA genes and primer design for 16S ribosomal DNA amplicons in metagenomic studies. PLoS One, 4, 2009, e7401.
21. 21 Zhou, X., Bent, S.J., Schneider, M.G., Davis, C.C., Islam, M.R., Forney, L.J., Characterization of vaginal microbial communities in adult healthy women using cultivation-independent methods. Microbiology 150 (2004), 2565–2573.
22. 22 Lajos, G.J., Passini Junior, R., Nomura, M.L., Amaral, E., Pereira, B.G., Milanez, H., et al. Cervical bacterial colonization in women with preterm labor or premature rupture of membranes. Rev Bras Ginecol Obstet 30 (2008), 393–399.
23. 23 Keelan, J.A., Payne, M.S., Vaginal microbiota during pregnancy: pathways of risk of preterm delivery in the absence of intrauterine infection?. Proc Natl Acad Sci U S A, 112, 2015, E6414.
24. 24 Nelson, D.B., Shin, H., Wu, J., Dominguez-Bello, M.G., The gestational vaginal microbiome and spontaneous preterm birth among nulliparous African American women. Am J Perinatol 33 (2016), 887–893.
25. 25 Prince, A.L., Ma, J., Kannan, P.S., Alvarez, M., Gisslen, T., Harris, R.A., et al. The placental microbiome is altered among subjects with spontaneous preterm birth with and without chorioamnionitis. Am J Obstet Gynecol 214 (2016), 627.e1–627.e16.
26. 26 Svare, J., Andersen, L.F., Langhoff-Roos, J., Madsen, H., Jensen, E.T., Bruun, B., et al. Uro-genital microbial colonization and threatening preterm delivery. Acta Obstet Gynecol Scand 73 (1994), 460–464.
27. 27 Tita, A.T., Cliver, S.P., Goepfert, A.R., Conner, M., Goldenberg, R.L., Hauth, J.C., et al. Impact of interconception antibiotics on the endometrial microbial flora. Am J Obstet Gynecol 196 (2007), 226.e1–226.e6.
28. 28 Swidsinski, A., Verstraelen, H., Loening-Baucke, V., Swidsinski, S., Mendling, W., Halwani, Z., Presence of a polymicrobial endometrial biofilm in patients with bacterial vaginosis. PLoS One, 8, 2013, e53997.
29. 29 Andrews, W.W., Hauth, J.C., Cliver, S.P., Conner, M.G., Goldenberg, R.L., Goepfert, A.R., Association of asymptomatic bacterial vaginosis with endometrial microbial colonization and plasma cell endometritis in nonpregnant women. Am J Obstet Gynecol 195 (2006), 1611–1616.
30. 30 Kumar, P.S., Brooker, M.R., Dowd, S.E., Camerlengo, T., Target region selection is critical determinant of community fingerprints generated by 16S pyrosequencing. PLoS One, 6, 2011, e20956.
31. 31 Ravel, J., Gajer, P., Abdo, Z., Schneider, G.M., Koenig, S.S., McCulle, S.L., et al. Vaginal microbiome of reproductive-age women. Proc Natl Acad Sci U S A 108:Suppl 1 (2011), 4680–4687.
32. 32 Brotman, R.M., Shardell, M.D., Gajer, P., Tracy, J.K., Zenilman, J.M., Ravel, J., et al. Interplay between the temporal dynamics of the vaginal microbiota and human papillomavirus detection. J Infect Dis 210 (2014), 1723–1733.
33. 33 DiGiulio, D.B., Callahan, B.J., McMurdie, P.J., Costello, E.K., Lyell, D.J., Robaczewska, A., et al. Temporal and spatial variation of the human microbiota during pregnancy. Proc Natl Acad Sci U S A 112 (2015), 11060–11065.
34. 34 Moreno, I., Codoner, F.M., Viella, F., Martinez-Blanch, J.F., Jimenez-Almazan, J., Alonso, R., et al. Evidence that the endometrial microbiota has an effect on implantation success or failure. Am J Obstet Gynecol 215 (2016), 684–703.