Mortality due to respiratory syncytial virus burden and risk factors

American Journal of Respiratory and Critical Care Medicine

Volumn 195, Issue 1, 2017, Pages 96-103

  Geoghegan, Sarah ^a   Erviti, Anabella ^a   Caballero, Mauricio T ^a   Vallone, Fernando ^b   Zanone, Stella M ^a   Losada, Juan Ves ^c   Bianchi, Alejandra ^a   Acosta, Patricio L ^a   Talarico, Laura B ^a   Ferretti, Adrian ^a   Grimaldi, Luciano Alva ^d   Sancilio, Andrea ^e   Dueñas, Karina ^e   Sastre, Gustavo ^f   Rodriguez, Andrea ^f   Ferrero, Fernando ^g   Barboza, Edgar ^h   Gago, Guadalupe Fernandez ⁱ   Nocito, Celina ^j   Flamenco, Edgardo ^k   RodriguezPerez, Alberto ^l   Rebec, Beatriz ^m   Martin Ferolla, F ^a   Libster, Romina ^a   Karron, Ruth A ⁿ   Bergel, Eduardo ^a   Polack, Fernando P ^a,o   more..

^a Buenos Aires ^*  (Argentina)

^b Region Sanitaria VI   (Argentina)

^c Hospital de Alta Complejidad El Cruce Dr Ńestor Kirchner ^*  (Argentina)

^d Hospital Zonal General de Agudos Lucio Me endez   (Argentina)

^e Hospital Interzonal General de Agudos Evita ^*  (Argentina)

^f Hospital Zonal General de Agudos Descentralizado Evita Pueblo ^*  (Argentina)

^g HOSPITAL GENERAL DE NIÑOS PEDRO DE ELIZALDE   (Argentina)

^h Hospital Zonal General de Agudos Dr Narciso Lopez   (Argentina)

ⁱ Universidad Provincial del Sudoeste   (Argentina)

^j Hospital Interzonal General de Agudos Dr Pedro Fiorito   (Argentina)

^k Hospital Zonal General de Agudos Dr Arturo Onativia   (Argentina)

^l Hospital Zonal General de Agudos Dr Alberto Eurnekián   (Argentina)

^m Hospital Interzonal General de Agudos Presidente Peŕon ^*  (Argentina)

ⁿ JOHNS HOPKINS UNIVERSITY   (United States)

^o VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

more..

Author keywords

Bacterial superinfections; Mortality; Pneumothorax; Respiratory syncytial virus

Indexed keywords

ARTICLE; CROSS-SECTIONAL STUDY; FEMALE; HOSPITALIZATION; HUMAN; HUMAN RESPIRATORY SYNCYTIAL VIRUS; INFANT; LOWER RESPIRATORY TRACT INFECTION; LOWEST INCOME GROUP; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PNEUMOTHORAX; PRIORITY JOURNAL; PROSPECTIVE STUDY; RESPIRATORY FAILURE; RISK FACTOR; SEPSIS; VIRUS LOAD; ARGENTINA; CLINICAL TRIAL; COMPLICATION; COST OF ILLNESS; EPIDEMIOLOGY; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; SEX DIFFERENCE; SOCIOECONOMICS; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA;

ARGENTINA; COST OF ILLNESS; CROSS-SECTIONAL STUDIES; FEMALE; HOSPITALIZATION; HUMANS; INFANT; LOGISTIC MODELS; MALE; PNEUMOTHORAX; PROSPECTIVE STUDIES; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; RISK FACTORS; SEPSIS; SEX FACTORS; SOCIOECONOMIC FACTORS;

EID: 85008656528     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201603-0658OC     Document Type: Article

References (31)

1. UN Millennium Development Goals Report 2015 [accessed 2016 Jun 10]. Available from: www.un.org/millenniumgoals/2015-MDG-Report
2. Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, O'Brien KL, Roca A, Wright PF, Bruce N, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet 2010;375: 1545-1555.
3. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2095-2128.
4. Middle Income Country Task Force. Sustainable access to vaccines in middle-income countries (MICs): a shared partner strategy report of the WHO-convened MIC taskforce. World Health Organization. 2015 Mar [accessed 2016 Jun 10]. Available from: http://www.who.int/immunization/sage/meetings/2015/april/Cernuschi-MIC-Strategy-SAGE-Apr2015.pdf
5. Weinberg GA, Erdman DD, Edwards KM, Hall CB, Walker FJ, Griffin MR, Schwartz B; New Vaccine Surveillance Network Study Group. Superiority of reverse-transcription polymerase chain reaction to conventional viral culture in the diagnosis of acute respiratory tract infections in children. J Infect Dis 2004;189:706-710.
6. Odendaal HJ, Elliott A, Kinney HC, Human M, Gaspar D, Petersen D, Randall B, Dempers J; Prenatal Alcohol and SIDS and Stillbirth (PASS) Network. Consent for autopsy research for unexpected death in early life. Obstet Gynecol 2011;117:167-171.
7. Ferolla FM, Hijano DR, Acosta PL, Rodríguez A, Dueñas K, Sancilio A, Barboza E, Caria A, Gago GF, Almeida RE, et al. Macronutrients during pregnancy and life-threatening respiratory syncytial virus infections in children. Am J Respir Crit Care Med 2013;187:983-990.
8. Libster R, Ferolla FM, Hijano DR, Acosta PL, Erviti A, Polack FP; INFANT Respiratory Network. Alcohol during pregnancy worsens acute respiratory infections in children. Acta Paediatr 2015;104:e494-e499.
9. Anker M, Black RE, Coldham C, Kalter HD, Quigley MA, Ross D, Snow RW. A standard verbal autopsy method for investigating causes of death in infants and children [accessed 2016 Jun 10]. Available from: http://www.who.int/csr/resources/publications/surveillance/whocdscsrisr994.pdf
10. Ali SA, Gern JE, Hartert TV, Edwards KM, Griffin MR, Miller EK, Gebretsadik T, Pappas T, Lee WM, Williams JV. Real-world comparison of two molecular methods for detection of respiratory viruses. Virol J 2011;8:332.
11. Victora CG, Huttly SR, Fuchs SC, Olinto MT. The role of conceptual frameworks in epidemiological analysis: a hierarchical approach. Int J Epidemiol 1997;26:224-227.
12. Ministerio de Salud de la Nación Argentina. Calendario Nacional de Vacunación. 2015. Available from: http://www.msal.gob. ar/images/stories/ryc/graficos/0000000628cnt-calendario-2015.pdf
13. American Academy of Pediatrics Committee on Infectious Diseases; American Academy of Pediatrics Bronchiolitis Guidelines Committee. Updated guidance for palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection. Pediatrics 2014;134:e620-e638.
14. Byington CL, Wilkes J, Korgenski K, Sheng X. Respiratory syncytial virus-associated mortality in hospitalized infants and young children. Pediatrics 2015;135:e24-e31.
15. Black RE, Cousens S, Johnson HL, Lawn JE, Rudan I, Bassani DG, Jha P, Campbell H, Walker CF, Cibulskis R, et al.; Child Health Epidemiology Reference Group of WHO and UNICEF. Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet 2010;375:1969-1987.
16. Cohen C, Walaza S, Moyes J, Groome M, Tempia S, Pretorius M, Hellferscee O, Dawood H, Chhagan M, Naby F, et al. Epidemiology of viral-associated acute lower respiratory tract infection among children <5 years of age in a high HIV prevalence setting, South Africa, 2009-2012. Pediatr Infect Dis J 2015;34:66-72.
17. Friedman B, Berdahl T, Simpson LA, McCormick MC, Owens PL, Andrews R, Romano PS. Annual report on health care for children and youth in the United States: focus on trends in hospital use and quality. Acad Pediatr 2011;11:263-279.
18. Hennus MP, Janssen R, Pennings JL, Hodemaekers HM, Kruijsen D, Jansen NJ, Meyaard L, van Vught AJ, Bont LJ. Host response to mechanical ventilation for viral respiratory tract infection. Eur Respir J 2012;40:1508-1515.
19. Given K, Schultz A, Douglas TA, Martin AC. Air leaks in children with acute bronchiolitis. J Paediatr Child Health 2008;44:604-606.
20. Kneyber MC, Blusse van Oud-Alblas H, van Vliet M, Uiterwaal CS, Kimpen JL, van Vught AJ. Concurrent bacterial infection and prolonged mechanical ventilation in infants with respiratory syncytial virus lower respiratory tract disease. Intensive Care Med 2005;31:680-685.
21. Hament JM, Aerts PC, Fleer A, van Dijk H, Harmsen T, Kimpen JL, Wolfs TF. Direct binding of respiratory syncytial virus to pneumococci: a phenomenon that enhances both pneumococcal adherence to human epithelial cells and pneumococcal invasiveness in a murine model. Pediatr Res 2005;58:1198-1203.
22. Caballero MT, Serra ME, Acosta PL, Marzec J, Gibbons L, Salim M, Rodriguez A, Reynaldi A, Garcia A, Bado D, et al. TLR4 genotype and environmental LPS mediate RSV bronchiolitis through Th2 polarization. J Clin Invest 2015;125:571-582.
23. Wolter N, Tempia S, Cohen C, Madhi SA, Venter M, Moyes J, Walaza S, Malope-Kgokong B, Groome M, du Plessis M, et al. High nasopharyngeal pneumococcal density, increased by viral coinfection, is associated with invasive pneumococcal pneumonia. J Infect Dis 2014;210:1649-1657.
24. Iroh Tam PY, Bernstein E, Ma X, Ferrieri P. Blood culture in evaluation of pediatric community-acquired pneumonia: a systematic review and meta-analysis. Hosp Pediatr 2015;5:324-336.
25. Madhi SA, Klugman KP; Vaccine Trialist Group. A role for Streptococcus pneumoniae in virus-associated pneumonia. Nat Med 2004;10:811-813.
26. Haeusler GM, Mechinaud F, Daley AJ, Starr M, Shann F, Connell TG, Bryant PA, Donath S, Curtis N. Antibiotic-resistant gram-negative bacteremia in pediatric oncology patients: risk factors and outcomes. Pediatr Infect Dis J 2013;32:723-726.
27. Alonso WJ, Laranjeira BJ, Pereira SA, Florencio CM, Moreno EC, Miller MA, Giglio R, Schuck-Paim C, Moura FE. Comparative dynamics, morbidity and mortality burden of pediatric viral respiratory infections in an equatorial city. Pediatr Infect Dis J 2012;31:e9-e14.
28. Anderson LJ, Parker RA, Strikas RL. Association between respiratory syncytial virus outbreaks and lower respiratory tract deaths of infants and young children. J Infect Dis 1990;161:640-646.
29. Djelantik IG, Gessner BD, Sutanto A, Steinhoff M, Linehan M, Moulton LH, Arjoso S. Case fatality proportions and predictive factors for mortality among children hospitalized with severe pneumonia in a rural developing country setting. J Trop Pediatr 2003;49:327-332.
30. Stockman LJ, Brooks WA, Streatfield PK, Rahman M, Goswami D, Nahar K, Rahman MZ, Luby SP, Anderson LJ. Challenges to evaluating respiratory syncytial virus mortality in Bangladesh, 2004-2008. PLoS One 2013;8:e53857.
31. Murray CJ, Lozano R, Flaxman AD, Serina P, Phillips D, Stewart A, James SL, Vahdatpour A, Atkinson C, Freeman MK, et al. Using verbal autopsy to measure causes of death: the comparative performance of existing methods. BMC Med 2014;12:5.