High nasopharyngeal pneumococcal density, increased by viral coinfection, is associated with invasive pneumococcal pneumonia

Journal of Infectious Diseases

Volumn 210, Issue 10, 2014, Pages 1649-1657

  Wolter, Nicole ^a,b,c   Tempia, Stefano ^d   Cohen, Cheryl ^e   Madhi, Shabir A ^f   Venter, Marietjie ^g   Moyes, Jocelyn ^j   Walaza, Sibongile ^k   Malope Kgokong, Babatyi ^l   Groome, Michelle ^m   Plessis, Mignon Du ⁿ   Magomani, Victoria ^a   Pretorius, Marthi ^e   Hellferscee, Orienka ⁱ   Dawood, Halima ^g   Kahn, Kathleen ^h   Variava, Ebrahim ^d   Klugman, Keith P ^e   Von Gottberg, Anne ^a,b,c  

^a NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

^b Faculty of Health Sciences   (United States)

^c Medical Research Council: Respiratory and Meningeal Pathogens Research Unit   (South Africa)

^d NATIONAL RESEARCH FOUNDATION   (South Africa)

^e UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^f UNIVERSITY OF PRETORIA   (South Africa)

^g Pietermaritzburg Metropolitan Hosp   (South Africa)

^h UNIVERSITY OF KWAZULU NATAL   (South Africa)

ⁱ Klerksdorp Hospital   (South Africa)

^j CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^k EMORY UNIVERSITY   (United States)

^l EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m UMEÅ UNIVERSITY   (Sweden)

ⁿ Studies of the Epidemiology of Epilepsy in Demographic Surveillance Systems   (Ghana)

more..

Author keywords

bacterial loads; colonization; invasive pneumococcal disease; pneumococcus; respiratory virus.

Indexed keywords

ACUTE LOWER RESPIRATORY TRACT INFECTION; ADENOVIRUS INFECTION; ADOLESCENT; ADULT; AGE DISTRIBUTION; ARTICLE; AUTUMN; BACTERIAL COLONIZATION; CHILD; COLONIZATION DENSITY; CONTROLLED STUDY; DENSITY; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; GENDER; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLUENZA; INVASIVE PNEUMOCOCCAL PNEUMONIA; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PROSPECTIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY VIRUS; RHINOVIRUS INFECTION; SOUTH AFRICA; SPRING; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; SUMMER; WINTER; AGED; BACTEREMIA; BACTERIAL LOAD; CLASSIFICATION; COMPLICATION; INFANT; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; MIXED INFECTION; NASOPHARYNX; PATHOLOGY; PRESCHOOL CHILD; RESPIRATORY TRACT INFECTION; VERY ELDERLY; VIROLOGY; VIRUS; VIRUS INFECTION; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTEREMIA; BACTERIAL LOAD; CHILD; CHILD, PRESCHOOL; COINFECTION; FEMALE; HUMANS; INFANT; MALE; MIDDLE AGED; NASOPHARYNX; PNEUMONIA, PNEUMOCOCCAL; PROSPECTIVE STUDIES; REAL-TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFECTIONS; SOUTH AFRICA; STREPTOCOCCUS PNEUMONIAE; VIRUS DISEASES; VIRUSES; YOUNG ADULT;

EID: 84912127239     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu326     Document Type: Article

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