Enterovirus-related diarrhoea in Guangdong, China: Clinical features and implications in hand, foot and mouth disease and herpangina

BMC Infectious Diseases

Volumn 16, Issue 1, 2016, Pages

  Zhou, Hong Tao ^a,b   Yi, Hai Su ^a   Guo, Yong Hui ^a   Pan, Yu Xian ^a   Tao, Shao Hua ^a   Wang, Bin ^a   Chen, Man Jun ^a   Yang, Mei ^a   Yu, Nan ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b HAINAN PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Clinical features; Diarrhoea; Enterovirus; Foot and mouth disease; Hand; Herpangina

Indexed keywords

UNCLASSIFIED DRUG; VIRAL PROTEIN; VIRAL PROTEIN 1;

5' UNTRANSLATED REGION; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CHILD; CHINA; CLINICAL FEATURE; CLINICAL STUDY; CONSCIOUSNESS DISORDER; CONTROLLED STUDY; CONVULSION; DEATH; DEHYDRATION; DIARRHEA; DISEASE ASSOCIATION; DISEASE DURATION; DISEASE SEVERITY; ENTEROVIRUS; FEMALE; GASTROINTESTINAL SYMPTOM; GENOTYPE; HAND FOOT AND MOUTH DISEASE; HEART MUSCLE INJURY; HERPANGINA; HOSPITAL ADMISSION; HUMAN; LIVER INJURY; MAJOR CLINICAL STUDY; MALE; MULTIPLE ORGAN FAILURE; PARALYSIS; PREVALENCE; RESPIRATORY TRACT INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROTYPE; ADOLESCENT; ENTEROVIRUS INFECTIONS; HAND, FOOT AND MOUTH DISEASE; ISOLATION AND PURIFICATION; PRESCHOOL CHILD; VIROLOGY;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; CHINA; DIARRHEA; ENTEROVIRUS; ENTEROVIRUS INFECTIONS; FEMALE; GENOTYPE; HAND, FOOT AND MOUTH DISEASE; HERPANGINA; HUMANS; MALE; PREVALENCE;

EID: 85008476023     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/s12879-016-1463-9     Document Type: Article

References (22)

1. National statutory report of incidence and death statistics of infectious disease. http://www.moh.gov.cn/publicfiles//business/htmlfiles/wsb/pyqxx/list.htm.
2. Hsiung GD, Wang JR. Enterovirus infections with special reference to enterovirus 71. J Microbiol Immunol Infect. 2000;33:1-8.
3. Stalkup JR, Chilukuri S. Enterovirus infections: a review of clinical presentation, diagnosis, and treatment. Dermatol Clin. 2002;20:217-23.
4. Distribution of causes of death among children aged < 5 years. http://apps. who.int/gho/data/view.main.CMDRWORLD?lang=en.
5. Nix WA, Oberste MS, Pallansch MA. Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens. J Clin Microbiol. 2006;44:2698-704.
6. Ge S, Yan Q, He S, et al. Specific primer amplification of the VP1 region directed by 5' UTR sequence analysis: enterovirus testing and identification in clinical samples from hand-foot-and-mouth disease patients. J Virol Methods. 2013;193:463-9.
7. Ruuska T, Vesikari T. Rotavirus disease in Finnish children: use of numerical scores for clinical severity of diarrhoeal episodes. Scand J Infect Dis. 1990;22: 259-67.
8. Chaimongkol N, Khamrin P, Suantai B, et al. A wide variety of diarrhea viruses circulating in pediatric patients in Thailand. Clin Lab. 2012;58:117-23.
9. Maslin J, Kohli E, Leveque N, et al. Characterisation of viral agents with potential to cause diarrhea in Djibouti. Med Trop (Mars). 2007;67:249-55.
10. Rao DC, Ananda Babu M, Raghavendra A, et al. Non-polio enteroviruses and their association with acute diarrhea in children in India. Infect Genet Evol. 2013;17:153-61.
11. Abe O, Kimura H, Minakami H, et al. Outbreak of gastroenteritis caused by echovirus type 6 in an orphanage in Japan. J Infect. 2000;41:285-6.
12. Oishi I, Maeda A, Otsu K, et al. An outbreak of diarrhea in school children associated with Coxsackie virus B-3 infection. Biken J. 1979;22:21-4.
13. Li CS, Chan PK, Tang JW. Prevalence of diarrhea viruses in hospitalized children in Hong Kong in 2008. J Med Virol. 2009;81:1903-11.
14. Zeng M, Chen J, Gong ST, et al. Epidemiological surveillance of norovirus and rotavirus diarrhea among outpatient children in five metropolitan cities. Zhonghua Er Ke Za Zhi. 2010;48:564-70.
15. Lee MK, Chan PK, Ho II, Lai WM. Enterovirus infection among patients admitted to hospital in Hong Kong in 2010: epidemiology, clinical characteristics, and importance of molecular diagnosis. J Med Virol. 2013;85:1811-7.
16. Li DD, Li H, Guo RN, et al. Pathogens of high incidence of other infectious diarrhea in Guangdong Province, from November 2008 to January 2009. Bing Du Xue Bao. 2010;26:150-2.
17. Xu J, Yang Y, Wang C, Jiang B. Rotavirus and coxsackievirus infection activated different profiles of toll-like receptors and chemokines in intestinal epithelial cells. Inflamm Res. 2009;58:585-92.
18. Zhang YC, Jiang SW, Gu WZ, et al. Clinicopathologic features and molecular analysis of enterovirus 71 infection: report of an autopsy case from the epidemic of hand, foot and mouth disease in China. Pathol Int. 2012;62:565-70.
19. Chi C, Sun Q, Wang S, et al. Robust antiviral responses to enterovirus 71 infection in human intestinalepithelial cells. Virus Res. 2013;176:53-60.
20. Navaneethan U, Giannella RA. Mechanisms of infectious diarrhea. Nat Clin Pract Gastroenterol Hepatol. 2008;5:637-47.
21. Carvalho RP, Kirchner E, Moura RA, Murahovschi J. Acute gastroenteritis associated with coxsackie B-6 virus in infants and children, in Sao Paulo, Brazil. Rev Inst Med Trop Sao Paulo. 1977;19:73-6.
22. Tai FH, Wang HC. Acute gastroenteritis associated with echovirus type 1. Southeast Asian J Trop Med Public Health. 1973;4:311-5.