Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain

BMJ

Volumn 328, Issue 7446, 2004, Pages 995-

  Mason, Lorna ^a   Moore, R Andrew ^a   Edwards, Jayne E ^a   Mcquay, Henry J ^a   Derry, Sheena ^a   Wiffen, Philip J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85007669161     PISSN: 09598138     EISSN: 14685833     Source Type: Journal    
DOI: 10.1136/bmj.38040.607141.EE     Document Type: Article

References (35)

1. British Medical Association, Royal Pharmaceutical Society of Great Britain. British national formulary. London: BMA, RPS, 2003. (No 45.)
2. Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971; 231: 232–5.
3. Morton I, Hall J. The Royal Society of Medicine: medicines. 6th ed. London: Bloomsbury,.
4. Reynolds JEF,ed. Martindale: the extra pharmacopoeia. 32nd ed. London: Royal Pharmaceutical Society, 1999.
5. Amann R, Peskar BA. Anti-inflammatory effects of aspirin and sodium salicylate. Eur J Pharmacol 2002; 447: 1–9.
6. Li Wan Po A. PJ practice checklist: topical analgesics. Pharmaceutical Journal, Dec, 1996. www.pharmj.com/Index.html
7. Moore RA, Tramer MR, Carroll D, Wiffen PJ, McQuay HJ. Quantitive systematic review of topically applied non-steroidal anti-inflammatory drugs. BMJ 1998; 316: 333–8.
8. Whitton T, Johnson RW. Topical preparations for chronic disorders of the knee: a review. Knee 2000; 7: 207–10.
9. Jadad AR, Carroll D, Moore A, McQuay H. Developing a database of published reports of randomised clinical trials in pain research. Pain 1996; 66: 239–46.
10. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996; 17: 1–12.
11. Smith LA, Oldman AD, McQuay HJ, Moore RA. Teasing apart quality and validity in systematic reviews: an example from acupuncture trials in chronic neck and back pain. Pain 2000; 86: 119–32.
12. Cook D, Sackett DL. On the clinically important difference. Ann Intern Med 1992; 117: A16–A17.
13. Morris JA, Gardner MJ. Calculating confidence intervals for relative risk, odds ratios and standardised ratios and rates. In: Gardner MJ, Altman DG,eds. Statistics with confidence—confidence intervals and statistical guidelines. London: British Medical Journal, 1995: 50–63.
14. L'Abbe KA, Detsky AS, O'Rourke K. Meta-analysis in clinical research. Ann Intern Med 1987; 107: 224–33.
15. Tramèr MR, Reynolds DJ, Moore RA, McQuay HJ. Impact of covert duplicate publication on meta-analysis: a case study. BMJ 1997; 315: 635–40.
16. Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF. Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of reporting of meta-analyses. Lancet 1999; 354: 1896–900.
17. Ginsberg F, Famaey JP. A double-blind study of topical massage with Rado-Salil ointment in mechanical low-back pain. J Int Med Res 1987; 15: 148–53.
18. Lester AA, Geller O, Bach GL, Fotiades P. Management of sprained ankles. A double-blind study. Practitioner 1981; 225: 935–6.
19. Rothhaar J, Thiel W. Percutaneous gel therapy of blunt athletic injuries. Med Welt 1982; 33: 1006–10. (In German.)
20. Stam C, Bonnet MS, van Haselen RA. The efficacy and safety of a homeopathic gel in the treatment of acute low back pain: a multi-centre, randomised, double-blind comparative clinical trial. Br Homeopath J 2001; 90: 21–28.
21. Algozzine GJ, Stein GH, Doering PL, Araujo OE, Akin KC. Trolamine salicylate cream in osteoarthritis of the knee. JAMA 1982; 247: 1311–3.
22. Bach GL, Fotiades P, Wanet G. Enelbin rheumatism ointment in rheumatic diseases. Results of a double-blind study for the determination of efficacy. Fortschr Med 1979; 97: 1249–52. (In German.)
23. Camus JP. Action de la myrtécaïne associée au salicylate de diéthylamine, en traitement local, dans diverses affections rheumatismales. Rheumatologie 1975; 27: 61–66.
24. Rutner M, Fitzek J, Jahnel-Kracht H, Otto J, Krause W. Treatment of rheumatism with a hydroxyethylsalicylate gel. Results of 2 clinical studies of effectiveness and bioavailability. Fortschr Med 1995; 113: 111–3. (In German.)
25. Shackel NA, Day RO, Kellett B, Brooks PM. Copper-salicylate gel for pain relief in osteoarthritis: a randomised controlled trial. Med J Aust 1997; 167: 134–6.
26. Wanet G. Controlled clinical study of a topic associating nopoxamine with diethylamine salicylate (Algesal suractive) in physical medicine and rehabilitation. J Belge Med Phys Rehabil 1979; 2: 119–26. (In French.)
27. Geller O, Bach GL, Fotiades P. Comparison of a salicylate-heparin gel with a monosubstance preparation. Results of a double-blind cross-over study. Munch Med Wochenschr 1980; 122: 1231–2. (In German.)
28. Golden EL. A double-blind comparison of orally ingested aspirin and a topically applied salicylate cream in the relief of rheumatic pain. Curr Ther Res 1978; 24: 524–9.
29. Diebschlag W, Nocker W. The effect of topical treatment in the treatment of disease in ankle sprains. Arzneimittelforschung 1987; 37: 1076–81. (In German.)
30. Frahm E, Elsasser U, Kammereit A. Topical treatment of acute sprains. Br J Clin Pract 1993; 47: 321–2.
31. Moore RA, Gavaghan D, Tramer MR, Collins SL, McQuay HJ. Size is everything—large amounts of information are needed to overcome random effects in estimating direction and magnitude of treatment effects. Pain 1998; 78: 209–16.
32. G⊘tzsche PC. Reporting of outcomes in arthritis trials measured on ordinal and interval scales is inadequate in relation to meta-analysis. Ann Rheum Dis 2001; 60: 349–52.
33. Edwards JE, McQuay HJ, Moore RA, Collins SL. Reporting of adverse effects in clinical trials should be improved: lessons from acute postoperative pain. J Pain Symptom Manage 1999; 18: 427–37.
34. Vaile JH, Davis P. Topical NSAIDs for musculoskeletal conditions. A review of the literature. Drugs 1998; 56: 783–99.
35. Barraclough K. There is no evidence that… BMJ 2003; 326: 1095.