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Volumn 37, Issue , 2017, Pages 85-89

Pathology of non-alcoholic fatty liver disease

Author keywords

fibrosis; liver biopsy; non alcoholic fatty liver disease; non alcoholic steatohepatitis

Indexed keywords

DIGESTIVE SYSTEM DISEASE ASSESSMENT; HEPATITIS; HISTOPATHOLOGY; HUMAN; LIVER CELL DAMAGE; LIVER FIBROSIS; LOBULAR INFLAMMATION; NONALCOHOLIC FATTY LIVER; REVIEW; SCORING SYSTEM; STEATOSIS ACTIVITY FIBROSIS SCORE; BIOPSY; FIBROSIS; LIVER; LIVER CELL; PATHOLOGY; SEVERITY OF ILLNESS INDEX;

EID: 85007564364     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.13301     Document Type: Review
Times cited : (257)

References (32)
  • 2
    • 84976479130 scopus 로고    scopus 로고
    • Global epidemiology of nonalcoholic fatty liver disease–Meta-analytic assessment of prevalence, incidence, and outcomes
    • Younossi Z, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease–Meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64:73–84.
    • (2016) Hepatology , vol.64 , pp. 73-84
    • Younossi, Z.1    Koenig, A.B.2    Abdelatif, D.3    Fazel, Y.4    Henry, L.5    Wymer, M.6
  • 3
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the american association for the study of liver diseases, American College of Gastroenterology, and the American Gastroenterological Association
    • Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the american association for the study of liver diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology. 2012;55:2005–2023.
    • (2012) Hepatology , vol.55 , pp. 2005-2023
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3
  • 4
    • 84945539188 scopus 로고    scopus 로고
    • Liver histology and NASH clinical trials: two pathologists’ perspective gastroenterology
    • Kleiner DE, Bedossa P. Liver histology and NASH clinical trials: two pathologists’ perspective gastroenterology. Gastroenterology. 2015;149:1305–1308.
    • (2015) Gastroenterology , vol.149 , pp. 1305-1308
    • Kleiner, D.E.1    Bedossa, P.2
  • 5
    • 84905403644 scopus 로고    scopus 로고
    • Role of liver biopsy in nonalcoholic fatty liver disease
    • Nalbantoglu IL, Brunt EM. Role of liver biopsy in nonalcoholic fatty liver disease. World J Gastroenterol. 2014;20:9026–9037.
    • (2014) World J Gastroenterol , vol.20 , pp. 9026-9037
    • Nalbantoglu, I.L.1    Brunt, E.M.2
  • 6
    • 62849123229 scopus 로고    scopus 로고
    • Effects of liver biopsy sample length and number of readings on sampling variability in nonalcoholic fatty liver disease
    • Vuppalanchi R, Unalp A, Van Natta ML, et al. Effects of liver biopsy sample length and number of readings on sampling variability in nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2009;7:481–486.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 481-486
    • Vuppalanchi, R.1    Unalp, A.2    Van Natta, M.L.3
  • 7
    • 84904747070 scopus 로고    scopus 로고
    • Utility and appropriateness of the fatty liver inhibition of progression (FLIP) algorithm and steatosis, activity, and fibrosis (SAF) score in the evaluation of biopsies of nonalcoholic fatty liver disease
    • Bedossa P, Consortium FLIP. Utility and appropriateness of the fatty liver inhibition of progression (FLIP) algorithm and steatosis, activity, and fibrosis (SAF) score in the evaluation of biopsies of nonalcoholic fatty liver disease. Hepatology. 2014;60:565–575.
    • (2014) Hepatology , vol.60 , pp. 565-575
    • Bedossa, P.1
  • 8
    • 84938057875 scopus 로고    scopus 로고
    • Liver fibrosis, but no other histologic features, is associated with long-term outcomes of patients with nonalcoholic fatty liver disease
    • Angulo P, Kleiner DE, Dam-Larsen S, et al. Liver fibrosis, but no other histologic features, is associated with long-term outcomes of patients with nonalcoholic fatty liver disease. Gastroenterology. 2015;149:389–397.
    • (2015) Gastroenterology , vol.149 , pp. 389-397
    • Angulo, P.1    Kleiner, D.E.2    Dam-Larsen, S.3
  • 9
    • 12244284662 scopus 로고    scopus 로고
    • Concurrence of histologic features of steatohepatitis with other forms of chronic liver disease
    • Brunt EM, Ramrakhiani S, Cordes BG, et al. Concurrence of histologic features of steatohepatitis with other forms of chronic liver disease. Mod Pathol. 2003;16:49–56.
    • (2003) Mod Pathol , vol.16 , pp. 49-56
    • Brunt, E.M.1    Ramrakhiani, S.2    Cordes, B.G.3
  • 11
    • 67349271289 scopus 로고    scopus 로고
    • Does liver appearance predict histopathologic findings: prospective analysis of routine liver biopsies during bariatric surgery
    • Dolce CJ, Russo M, Keller JE, et al. Does liver appearance predict histopathologic findings: prospective analysis of routine liver biopsies during bariatric surgery. Surg Obes Relat Dis. 2009;5:323–328.
    • (2009) Surg Obes Relat Dis , vol.5 , pp. 323-328
    • Dolce, C.J.1    Russo, M.2    Keller, J.E.3
  • 12
    • 84929266699 scopus 로고    scopus 로고
    • Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
    • Neuschwander-Tetri BA, Loomba R, Sanyal AJ, et al. NASH Clinical Research Network. Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial. Lancet. 2015;385:956–965.
    • (2015) Lancet , vol.385 , pp. 956-965
    • Neuschwander-Tetri, B.A.1    Loomba, R.2    Sanyal, A.J.3
  • 13
    • 84960140218 scopus 로고    scopus 로고
    • Elafibranor, an agonist of the peroxisome proliferator-activated receptor-α and -δ, induces resolution of nonalcoholic steatohepatitis without fibrosis worsening
    • Ratziu V, Harrison SA, Francque S, et al. Elafibranor, an agonist of the peroxisome proliferator-activated receptor-α and -δ, induces resolution of nonalcoholic steatohepatitis without fibrosis worsening. Gastroenterology. 2016;150:1147–1159.
    • (2016) Gastroenterology , vol.150 , pp. 1147-1159
    • Ratziu, V.1    Harrison, S.A.2    Francque, S.3
  • 15
    • 84927796763 scopus 로고    scopus 로고
    • Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: implications for prognosis and clinical management
    • McPherson S, Hardy T, Henderson E, Burt AD, Day CP, Anstee QM. Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: implications for prognosis and clinical management. J Hepatol. 2015;62:1148–1155.
    • (2015) J Hepatol , vol.62 , pp. 1148-1155
    • McPherson, S.1    Hardy, T.2    Henderson, E.3    Burt, A.D.4    Day, C.P.5    Anstee, Q.M.6
  • 16
    • 77649337140 scopus 로고    scopus 로고
    • Vos, MB, Brunt EM. Nonalcoholic steatohepatitis: pathology and pathophysiology
    • Tiniakos DG. Vos, MB, Brunt EM. Nonalcoholic steatohepatitis: pathology and pathophysiology. Annu Rev Pathol. 2010;5:145–171.
    • (2010) Annu Rev Pathol , vol.5 , pp. 145-171
    • Tiniakos, D.G.1
  • 17
    • 24144444669 scopus 로고    scopus 로고
    • Histopathology of pediatric nonalcoholic fatty liver disease
    • Schwimmer JB, Behling C, Newbury R, et al. Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology. 2005;42:641–649.
    • (2005) Hepatology , vol.42 , pp. 641-649
    • Schwimmer, J.B.1    Behling, C.2    Newbury, R.3
  • 18
    • 84924938800 scopus 로고    scopus 로고
    • Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta-analysis of paired-biopsy studies
    • Singh S, Allen AM, Wang Z, Prokop LJ, Murad MH, Loomba R. Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta-analysis of paired-biopsy studies. Clin Gastroenterol Hepatol. 2015;13:643–654.
    • (2015) Clin Gastroenterol Hepatol , vol.13 , pp. 643-654
    • Singh, S.1    Allen, A.M.2    Wang, Z.3    Prokop, L.J.4    Murad, M.H.5    Loomba, R.6
  • 19
    • 33750606061 scopus 로고    scopus 로고
    • Long-term follow-up of patients with NAFLD and elevated liver enzymes
    • Ekstedt M, Franzén LE, Mathiesen UL, et al. Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology. 2006;44:865–873.
    • (2006) Hepatology , vol.44 , pp. 865-873
    • Ekstedt, M.1    Franzén, L.E.2    Mathiesen, U.L.3
  • 20
    • 79957521377 scopus 로고    scopus 로고
    • Pathologic criteria for nonalcoholic steatohepatitis: interprotocol agreement and ability to predict liver-related mortality
    • Jun
    • Younossi ZM, Stepanova M, Rafiq N, et al. Pathologic criteria for nonalcoholic steatohepatitis: interprotocol agreement and ability to predict liver-related mortality. Hepatology. 2011 Jun;53:1874–1882.
    • (2011) Hepatology , vol.53 , pp. 1874-1882
    • Younossi, Z.M.1    Stepanova, M.2    Rafiq, N.3
  • 21
    • 0034950652 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese
    • Dixon JB, Bhathal PS, O'Brien PE. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology. 2001;121:91–100.
    • (2001) Gastroenterology , vol.121 , pp. 91-100
    • Dixon, J.B.1    Bhathal, P.S.2    O'Brien, P.E.3
  • 22
    • 46249084411 scopus 로고    scopus 로고
    • A clinical scoring system for predicting nonalcoholic steatohepatitis in morbidly obese patients
    • Campos GM, Bambha K, Vittinghoff E, et al. A clinical scoring system for predicting nonalcoholic steatohepatitis in morbidly obese patients. Hepatology. 2008;47:1916–1923.
    • (2008) Hepatology , vol.47 , pp. 1916-1923
    • Campos, G.M.1    Bambha, K.2    Vittinghoff, E.3
  • 23
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
    • Ludwig J, Viggiano TR, McGill DB, Oh BJ. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc. 1980;55:434–438.
    • (1980) Mayo Clin Proc , vol.55 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3    Oh, B.J.4
  • 24
    • 79959573040 scopus 로고    scopus 로고
    • Endpoints and clinical trial design for nonalcoholic steatohepatitis
    • Sanyal AJ, Brunt EM, Kleiner DE, et al. Endpoints and clinical trial design for nonalcoholic steatohepatitis. Hepatology. 2011;54:344–353.
    • (2011) Hepatology , vol.54 , pp. 344-353
    • Sanyal, A.J.1    Brunt, E.M.2    Kleiner, D.E.3
  • 25
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41:1313–1321.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3
  • 26
    • 84868235041 scopus 로고    scopus 로고
    • Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients
    • Bedossa P, Poitou C, Veyrie N, et al. Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients. Hepatology. 2012;56:1751–1759.
    • (2012) Hepatology , vol.56 , pp. 1751-1759
    • Bedossa, P.1    Poitou, C.2    Veyrie, N.3
  • 27
    • 63349106888 scopus 로고    scopus 로고
    • Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network
    • Brunt EM, Kleiner DE, Wilson LA, et al. NASH Clinical Research Network. Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network. Hepatology. 2009;46:809–820.
    • (2009) Hepatology , vol.46 , pp. 809-820
    • Brunt, E.M.1    Kleiner, D.E.2    Wilson, L.A.3
  • 28
    • 40949123364 scopus 로고    scopus 로고
    • Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis
    • Lackner C, Gogg-Kamerer M, Zatloukal K, Stumptner C, Brunt EM, Denk H. Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis. J Hepatol. 2008;48:821–828.
    • (2008) J Hepatol , vol.48 , pp. 821-828
    • Lackner, C.1    Gogg-Kamerer, M.2    Zatloukal, K.3    Stumptner, C.4    Brunt, E.M.5    Denk, H.6
  • 29
    • 84928209634 scopus 로고    scopus 로고
    • Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up
    • Ekstedt M, Hagstrom H, Nasr P, et al. Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up. Hepatology. 2015;61:1547–1554.
    • (2015) Hepatology , vol.61 , pp. 1547-1554
    • Ekstedt, M.1    Hagstrom, H.2    Nasr, P.3
  • 31
    • 79952231349 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings
    • Brunt EM, Kleiner DE, Wilson LA, Belt P, Neuschwander-Tetri BA, Network NCR. Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings. Hepatology. 2011;53:810–820.
    • (2011) Hepatology , vol.53 , pp. 810-820
    • Brunt, E.M.1    Kleiner, D.E.2    Wilson, L.A.3    Belt, P.4    Neuschwander-Tetri, B.A.5    Network, N.C.R.6
  • 32
    • 84986222780 scopus 로고    scopus 로고
    • SAF score and mortality in NAFLD after up to 41 years of follow-up
    • Hagström H, Nasr P, Ekstedt M, et al. SAF score and mortality in NAFLD after up to 41 years of follow-up. Scand J Gastroenterol. 2016;doi:10.1080/00365521.2016 1230779
    • (2016) Scand J Gastroenterol , pp. 1230779
    • Hagström, H.1    Nasr, P.2    Ekstedt, M.3


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