Primary and secondary hemophagocytic lymphohistiocytosis have different patterns of T-cell activation, differentiation and repertoire

European Journal of Immunology

Volumn 47, Issue 2, 2017, Pages 364-373

  Ammann, Sandra ^a,b   Lehmberg, Kai ^c   zur Stadt, Udo ^c   Janka, Gritta ^c   Rensing Ehl, Anne ^a   Klemann, Christian ^a,d   Heeg, Maximilian ^a,d   Bode, Sebastian ^a,d   Fuchs, Ilka ^a   Ehl, Stephan ^a,d  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Hemophagocytic lymphohistiocytosis; HLA DR; Perforin; Primary HLH; Secondary HLH; T cell activation

Indexed keywords

CD45RA ANTIGEN; CD57 ANTIGEN; CHEMOKINE RECEPTOR CCR7; HLA DR ANTIGEN; INTERLEUKIN 7 RECEPTOR; PERFORIN; PROGRAMMED DEATH 1 RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; CYTOTOXIC T LYMPHOCYTE; EPSTEIN BARR VIRUS INFECTION; HEMOPHAGOCYTIC SYNDROME; HUMAN; IMMUNOPATHOGENESIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE SUBPOPULATION; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEROLOGY; T LYMPHOCYTE ACTIVATION; CELL CULTURE; CELL DIFFERENTIATION; COMPARATIVE STUDY; COMPLICATION; FEMALE; GENETICS; IMMUNOLOGY; INFANT; LYMPHOCYTE ACTIVATION; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; METABOLISM; NEWBORN; VIRUS DISEASES;

ANTIGENS, CD57; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; FEMALE; HLA-DR ANTIGENS; HUMANS; INFANT; INFANT, NEWBORN; LYMPHOCYTE ACTIVATION; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; PERFORIN; RECEPTORS, ANTIGEN, T-CELL; VIRUS DISEASES;

EID: 85007557270     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201646686     Document Type: Article

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