Epidemiologic and spatiotemporal Characterization of influenza and severe acute respiratory infection in Uganda, 2010-2015

Annals of the American Thoracic Society

Volumn 13, Issue 12, 2016, Pages 2159-2168

  Cummings, Matthew J ^a   Bakamutumaho, Barnabas ^b   Kayiwa, John ^b   Byaruhanga, Timothy ^b   Owor, Nicholas ^b   Namagambo, Barbara ^b   Wolf, Allison ^a   Wamala, Joseph F ^c,d   Morse, Stephen S ^e   Lutwama, Julius J ^b   O'Donnell, Max R ^a,e  

^a Howard Hughes Medical Institute   (United States)

^b UGANDA VIRUS RESEARCH INSTITUTE   (Uganda)

^c MINISTRY OF HEALTH   (Uganda)

^d WORLD HEALTH ORGANIZATION   (Switzerland)

^e Mailman School of Public Health   (United States)

Author keywords

Acute respiratory infection; Africa south of the sahara; Epidemiology; Influenza; Spatiotemporal analysis

Indexed keywords

2009 H1N1 INFLUENZA; ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; DISEASE SEVERITY; FEMALE; GENE LOCUS; GROUPS BY AGE; HOSPITAL MORTALITY; HOSPITALIZATION; HUMAN; INFANT; INFLUENZA A (H3N2); INFLUENZA A VIRUS (H1N1); INFLUENZA A VIRUS (H3N2); INFLUENZA B; INFLUENZA B VIRUS; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MIDDLE AGED; MORBIDITY; NONHUMAN; PROSPECTIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; SEASONAL VARIATION; SENTINEL SURVEILLANCE; SEVERE ACUTE RESPIRATORY SYNDROME; SPATIOTEMPORAL ANALYSIS; UGANDA; URBAN AREA; VIRUS TRANSMISSION; ACUTE DISEASE; INFLUENZA; MULTIVARIATE ANALYSIS; PRESCHOOL CHILD; SEASON; STATISTICAL MODEL; VACCINATION; YOUNG ADULT;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; CHILD; CHILD, PRESCHOOL; FEMALE; HOSPITAL MORTALITY; HUMANS; INFANT; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROSPECTIVE STUDIES; RISK FACTORS; SEASONS; SENTINEL SURVEILLANCE; SPATIO-TEMPORAL ANALYSIS; UGANDA; VACCINATION; YOUNG ADULT;

EID: 85007494770     PISSN: 23296933     EISSN: 23256621     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201607-561OC     Document Type: Article

References (35)

1. World Lung Foundation. Acute respiratory infections atlas. New York, NY: World Lung Foundation; 2010.
2. World Health Organization. Influenza (seasonal). Fact sheet No. 211. 2014. [accessed 2016 Jun. 3]. Available from: http://www.who.int/mediacentre/factsheets/fs211/en/
3. Carson SS, Fowler RA, Cobb JP, Arabi YM, Ingbar DH; ATS Taskforce on Emerging Pathogens. Global participation in core data sets for emerging pathogens. Am J Respir Crit Care Med 2015;191:728-730.
4. World Health Organization. Limiting spread: limiting the spread of pandemic, zoonotic, and seasonal epidemic influenza. Geneva, Switzerland: World Health Organization; 2010. [accessed 2016 Jun. 3]. Available from: http://www.who.int/influenza/resources/research/research-agenda-influenza-stream-2-limiting-spread.pdf
5. Katz MA, Schoub BD, Heraud JM, Breiman RF, Njenga MK, Widdowson MA. Influenza in Africa: uncovering the epidemiology of a long-overlooked disease. J Infect Dis 2012;206:S1-S4.
6. Fischer WA II, Gong M, Bhagwanjee S, Sevransky J. Global burden of influenza as a cause of cardiopulmonary morbidity and mortality. Glob Heart 2014;9:325-336.
7. Radin JM, Katz MA, Tempia S, Talla Nzussouo N, Davis R, Duque J, Adedeji A, Adjabeng MJ, Ampofo WK, Ayele W, et al. Influenza surveillance in 15 countries in Africa, 2006-2010. J Infect Dis 2012;206:S14-S21.
8. Ortiz JR, Lafond KE, Wong TA, Uyeki TM. Pandemic influenza in Africa, lessons learned from 1968: a systematic review of the literature. Influenza Other Respi Viruses 2012;6:11-24.
9. Cummings MJ, Bakamutumaho B, Lutwama JJ, Kayiwa J, Byaruhanga T, Namagambo B, Wolf A, Wamala JF, O'Donnell MR. Clinical epidemiology and seasonality of influenza-associated severe acute respiratory illness in Uganda, 2010-2015 [abstract]. Am J Respir Crit Care Med 2016;193:A20168.
10. Lutwama JJ, Bakamutumaho B, Kayiwa JT, Chiiza R, Namagambo B, Katz MA, Geissler AL. Clinic- and hospital-based sentinel influenza surveillance, Uganda 2007-2010. J Infect Dis 2012;206:S87-S93.
11. World Health Organization. Global standards and tools for influenza surveillance. Geneva, Switzerland: World Health Organization; 2011. [accessed 2016 Jun. 3]. Available from: http://www.who.int/influenza/resources/documents/technical-consultation/en/
12. Kulldorff M. A spatial scan statistic. Commun Statist Theory Meth 1997;26:1481-1496.
13. Adjemian J, Olivier KN, Seitz AE, Falkinham JO III, Holland SM, Prevots DR. Spatial clusters of nontuberculous mycobacterial lung disease in the United States. Am J Respir Crit Care Med 2012;186:553-558.
14. Uganda Bureau of Statistics. National population and housing census 2014. Kampala, Uganda: Uganda Bureau of Statistics; 2014.
15. World Bank. Climate change knowledge portal. Washington, DC; 2016. [accessed 2016 Aug. 11].
16. Ortiz JR, Sotomayor V, Uez OC, Oliva O, Bettels D, McCarron M, Bresee JS, Mounts AW. Strategy to enhance influenza surveillance worldwide. Emerg Infect Dis 2009;15:1271-1278.
17. Murray CJ, Lopez AD, Chin B, Feehan D, Hill KH. Estimation of potential global pandemic influenza mortality on the basis of vital registry data from the 1918-20 pandemic: a quantitative analysis. Lancet 2006;368:2211-2218.
18. Smith RD, Keogh-Brown MR. Macroeconomic impact of pandemic influenza and associated policies in Thailand, South Africa and Uganda. Influenza Other Respi Viruses 2013;7:64-71.
19. Hirve S, Lambach P, Paget J, Vandemaele K, Fitzner J, Zhang W. Seasonal influenza vaccine policy, use and effectiveness in the tropics and subtropics - a systematic literature review. Influenza Other Respi Viruses 2016;10:254-267.
20. Bell DM, Weisfuse IB, Hernandez-Avila M, Del Rio C, Bustamante X, Rodier G. Pandemic influenza as 21st century urban public health crisis. Emerg Infect Dis 2009;15:1963-1969.
21. Alirol E, Getaz L, Stoll B, Chappuis F, Loutan L. Urbanisation and infectious diseases in a globalised world. Lancet Infect Dis 2011;11:131-141.
22. Lee SS, Wong NS. The clustering and transmission dynamics of pandemic influenza A (H1N1) 2009 cases in Hong Kong. J Infect 2011;63:274-280.
23. Uganda Bureau of Statistics. The state of Uganda population report 2014. Kampala, Uganda: Uganda Bureau of Statistics; 2014.
24. Kwiringira J, Atekyereza P, Niwagaba C, Günther I. Descending the sanitation ladder in urban Uganda: evidence from Kampala Slums. BMC Public Health 2014;14:624.
25. Unger A, Riley LW. Slum health: from understanding to action. PLoS Med 2007;4:1561-1566.
26. Tamerius J, Nelson MI, Zhou SZ, Viboud C, Miller MA, Alonso WJ. Global influenza seasonality: reconciling patterns across temperate and tropical regions. Environ Health Perspect 2011;119:439-445.
27. Tamerius JD, Shaman J, Alonso WJ, Bloom-Feshbach K, Uejio CK, Comrie A, Viboud C. Environmental predictors of seasonal influenza epidemics across temperate and tropical climates. PLoS Pathog 2013;9:e1003194.
28. [Published erratum appears in PLoS Pathog 9.]
29. Osterholm MT, Kelley NS, Sommer A, Belongia EA. Efficacy and effectiveness of influenza vaccines: a systematic review and metaanalysis. Lancet Infect Dis 2012;12:36-44.
30. World Health Organization. Recommended composition of influenza virus vaccines for use in the 2016 Southern Hemisphere influenza season. Geneva, Switzerland: World Health Organization; 2015.
31. Chaves SS, Aragon D, Bennett N, Cooper T, D'Mello T, Farley M, Fowler B, Hancock E, Kirley PD, Lynfield R, et al. Patients hospitalized with laboratory-confirmed influenza during the 2010-2011 influenza season: exploring disease severity by virus type and subtype. J Infect Dis 2013;208:1305-1314.
32. Cohen AL, Hellferscee O, Pretorius M, Treurnicht F, Walaza S, Madhi S, Groome M, Dawood H, Variava E, Kahn K, et al. Epidemiology of influenza virus types and subtypes in South Africa, 2009-2012. Emerg Infect Dis 2014;20:1162-1169.
33. Cohen C, Simonsen L, Kang JW, Miller M, McAnerney J, Blumberg L, Schoub B, Madhi SA, Viboud C. Elevated influenza-related excess mortality in South African elderly individuals, 1998-2005. Clin Infect Dis 2010;51:1362-1369.
34. Källander K, Hildenwall H, Waiswa P, Galiwango E, Peterson S, Pariyo G. Delayed care seeking for fatal pneumonia in children aged under five years in Uganda: a case-series study. Bull World Health Organ 2008;86:332-338.
35. Cohen C, Simonsen L, Sample J, Kang JW, Miller M, Madhi SA, Campsmith M, Viboud C. Influenza-related mortality among adults aged 25-54 years with AIDS in South Africa and the United States of America. Clin Infect Dis 2012;55:996-1003.