Novel Financing Model for Neglected Tropical Diseases: Development Impact Bonds Applied to Sleeping Sickness and Rabies Control

PLoS Neglected Tropical Diseases

Volumn 10, Issue 11, 2016, Pages

  Welburn, Susan Christina ^a   Bardosh, Kevin Louis ^a   Coleman, Paul Gerard ^b,c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c H2O Venture Partners   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AFRICAN TRYPANOSOMIASIS; ARTICLE; DEVELOPMENT IMPACT BOND; DISEASE CONTROL; DISEASE COURSE; DISEASE ELIMINATION; FINANCIAL MANAGEMENT; FINANCIAL STATEMENT; FUNDING; HEALTH PROGRAM; HUMAN; IMMUNE SYSTEM; INCIDENCE; MODEL; RABIES; TROPICAL DISEASE; TRYPANOSOMA BRUCEI RHODESIENSE; ECONOMIC MODEL; ECONOMICS; NEGLECTED DISEASE; TIME FACTOR; TROPICAL MEDICINE;

HUMANS; MODELS, ECONOMIC; NEGLECTED DISEASES; RABIES; TIME FACTORS; TROPICAL MEDICINE; TRYPANOSOMIASIS, AFRICAN;

EID: 85007349602     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0005000     Document Type: Article

References (27)

1. Hotez PJ, Fenwick A, Savioli L, Molyneux DH, Rescuing the bottom billion through control of neglected tropical diseases. Lancet. 2009;373: 1570–1575. doi: 10.1016/S0140-6736(09)60233-619410718
2. Maudlin I, African trypanosomiasis. Ann Trop Med Parasitol. 2006;100: 679–701. doi: 10.1179/136485906X11221117227648
3. Brun R, Blum J, Chappuis F, Burri C, Human African trypanosomiasis. Lancet. 2010;375: 148–159. doi: 10.1016/S0140-6736(09)60829-119833383
4. Odiit M, Coleman P, Liu WC, McDermott JJ, Fèvre EM, Welburn SC, Woolhouse M, Quantifying the level of under-detection of Trypanosoma brucei rhodesiense sleeping sickness cases. Trop Med Int Health. 2005;10: 840–849. doi: 10.1111/j.1365-3156.2005.01470.x16135190
5. Acup C, Picozzi K, Waiswa C, Welburn SC, Factors Influencing Passive Surveillance for zoonotic T. b. rhodesiense Human African Trypanosomiasis in Uganda. Acta Tropica. 2016;
6. La Greca F, Magez S, Vaccination against trypanosomiasis: Can it be done or is the trypanosome truly the ultimate immune destroyer and escape artist?Hum Vaccines. 2011;11: 1225–1233.
7. Shaw AP, Wint GR, Cecchi G, Torr SJ, Mattioli RC, Robinson TP, Mapping the benefit-cost ratios of interventions against bovine trypanosomosis in Eastern Africa. Preventive Veterinary Medicine. 2015;122(4): 406–416. doi: 10.1016/j.prevetmed.2015.06.01326166771
8. Holmes P, On the Road to Elimination of Rhodesiense Human African Trypanosomiasis: First WHO Meeting of Stakeholders. PloS Negl Trop Dis. 2015;9(4): e0003571. doi: 10.1371/journal.pntd.000357125836650
9. Simarro PP, Jannin J, Cattand P, Eliminating human African trypanosomiasis: where do we stand and what comes next?PLoS Med. 2008;5: e55. doi: 10.1371/journal.pmed.005005518303943
10. Molyneux D, Ndung'u J, Maudlin I, Controlling sleeping sickness—"when will they ever learn?". PLoS Negl Trop Dis. 2010; 4:e609. doi: 10.1371/journal.pntd.000060920520799
11. Fèvre EM, Odiit M, Coleman PG, Woolhouse ME, Welburn SC, Estimating the burden of rhodesiense sleeping sickness during an outbreak in Serere, eastern Uganda. BMC Public Health. 2008;8: 96. doi: 10.1186/1471-2458-8-9618366755
12. Welburn SC, Coleman PG, Fevre E, Maudlin I, Sleeping sickness–a tale of two diseases. Trends Parasitol. 2001;17: 19–24. 11137736
13. Welburn SC, Maudlin I, Molyneux D, Beyond Tsetse—Implications for Research and Control of Human African Trypanosomiasis. Trends Parasitol. 2016;32(3)
14. Fèvre EM, Coleman PG, Odiit M, Magona JW, Welburn SC, Woolhouse ME, The origins of a new Trypanosoma brucei rhodesiense sleeping sickness outbreak in eastern Uganda. Lancet. 2001;358: 625–628. 11530149
15. Welburn SC, Picozzi K, Fevre EM, Coleman PG, Odiit M, Carrington M, Maudlin I, Identification of human infective trypanosomes in animal reservoir of sleeping sickness in Uganda by means of serum-resistance-associated (SRA) gene. Lancet. 2001;358: 2017–19. 11755607
16. Welburn SC, Fèvre EM, Coleman PG, Odiit M, Maudlin I, Crisis, what crisis? Control of Rhodesian sleeping sickness. Trends Parasitol. 2006;22: 123–128. doi: 10.1016/j.pt.2006.01.01116458071
17. Kajunguri D, Hargrove JW, Ouifki R, Mugisha JYT, Coleman PG, Welburn SC, Modelling the use of insecticide-treated cattle to control tsetse and Trypanosoma brucei rhodesiense in a multi-host population. Bulletin of Mathematical Biology. 2014;76(3): 673–696. doi: 10.1007/s11538-014-9938-624584715
18. Fyfe J, Picozzi K, Bardosh K, Waiswa C, Welburn SC, Impact of mass chemotherapy in domestic livestock to control zoonotic T.b. rhodesiense. Acta Tropica. 2016;
19. Welburn SC, Coleman P, Zinsstag J, Schelling E, Waltner-Toews D, Whittaker M, Tanner M, Human and Animal African Trypanosomiasis. In: One Health: The Theory and Practice of Integrated Health Approaches. CABI International. 2015. pp. 201–221.
20. Okello WO, Muhanguzi D, MacLeod ET, Welburn SC, Waiswa C, Shaw AP, Contribution of draft cattle to rural livelihoods in a district of southeastern Uganda endemic for bovine parasitic diseases: an economic evaluation. Parasit Vectors. 2015; 8(1): 1–9.
21. Bardosh K, Waiswa C, Welburn SC, Conflict of interest: use of pyrethroids and amidines against tsetse and ticks in zoonotic sleeping sickness endemic areas of Uganda. Parasit Vectors. 2013;6: 204. doi: 10.1186/1756-3305-6-20423841963
22. Picozzi K, Fevre EM, Odiit M, Carrington M, Eisler MC, Maudlin I, Welburn SC, Sleeping sickness in Uganda: a thin line between two fatal diseases. British Medical Journal, 2005;331(7527): 1238–41doi: 10.1136/bmj.331.7527.123816308383
23. Simarro PP, Cecchi G, Franco JR, Paone M, Diarra A, Priotto G, Mattioli RC, Jannin JG, Monitoring the progress towards the elimination of Gambiense human African trypanosomiasis. PLoS Negl Trop Dis. 2015; 9(6): e0003785doi: 10.1371/journal.pntd.000378526056823
24. Centre for International Development and Social Finance. Case Study 1: Reduction of Rhodesian sleeping sickness in Uganda. 2013. Available: http://www.socialfinance.org.uk/resources/socoal-finance/dib-workinggroup-report-consultation-dr
25. Singh Grewal A, Pandita D, Bhardwaj S, Lather V, Recent Updates on Development of Drug Molecules for Human African Trypanosomiasis. Current Topics in Medicinal Chemistry. 2016;16(20): 2245–65. 27072715
26. Editorial Lancet, Time to eliminate rabies. Lancet. 2015;386 (10012): 2446.
27. DfID. UK development bonds will combat global poverty. 2014. Available: https://www.gov.uk/government/news/uk-development-bonds-will-combat-global-poverty.