메뉴 건너뛰기




Volumn 107, Issue 12, 2016, Pages 1730-1735

Comparison of tumor-infiltrating lymphocytes between primary and metastatic tumors in breast cancer patients

Author keywords

Immune microenvironment; immunohistochemistry; metastatic breast tumor; primary breast tumor; tumor infiltrating lymphocytes

Indexed keywords

ANTIBODY; CD4 ANTIGEN; CD8 ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HLA ANTIGEN CLASS 1; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; TRANSCRIPTION FACTOR FOXP3; BIOLOGICAL MARKER;

EID: 85007335629     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.13101     Document Type: Article
Times cited : (117)

References (35)
  • 1
    • 40349094954 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression
    • DeNardo DG, Coussens LM. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res 2007; 9(4): 212.
    • (2007) Breast Cancer Res , vol.9 , Issue.4 , pp. 212
    • DeNardo, D.G.1    Coussens, L.M.2
  • 2
    • 44849101184 scopus 로고    scopus 로고
    • The humoral immune system has a key prognostic impact in node-negative breast cancer
    • (Jul 1);
    • Schmidt M, Bohm D, von Torne C et al. The humoral immune system has a key prognostic impact in node-negative breast cancer. Cancer Res 2008 (Jul 1); 68: 5405–13.
    • (2008) Cancer Res , vol.68 , pp. 5405-5413
    • Schmidt, M.1    Bohm, D.2    von Torne, C.3
  • 3
    • 73949092850 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer
    • (Jan 1);
    • Denkert C, Loibl S, Noske A et al. Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. J Clin Oncol 2010 (Jan 1); 28(1): 105–13.
    • (2010) J Clin Oncol , vol.28 , Issue.1 , pp. 105-113
    • Denkert, C.1    Loibl, S.2    Noske, A.3
  • 4
    • 82955217260 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
    • West NR, Milne K, Truong PT, Macpherson N, Nelson BH, Watson PH. Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer. Breast Cancer Res 2011; 13(6): R126.
    • (2011) Breast Cancer Res , vol.13 , Issue.6 , pp. R126
    • West, N.R.1    Milne, K.2    Truong, P.T.3    Macpherson, N.4    Nelson, B.H.5    Watson, P.H.6
  • 5
    • 84865191854 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer
    • (Apr);
    • Ono M, Tsuda H, Shimizu C et al. Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer. Breast Cancer Res Treat 2012 (Apr); 132: 793–805.
    • (2012) Breast Cancer Res Treat , vol.132 , pp. 793-805
    • Ono, M.1    Tsuda, H.2    Shimizu, C.3
  • 6
    • 84866508637 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes are important pathologic predictors for neoadjuvant chemotherapy in patients with breast cancer
    • (Oct);
    • Yamaguchi R, Tanaka M, Yano A et al. Tumor-infiltrating lymphocytes are important pathologic predictors for neoadjuvant chemotherapy in patients with breast cancer. Hum Pathol 2012 (Oct); 43: 1688–94.
    • (2012) Hum Pathol , vol.43 , pp. 1688-1694
    • Yamaguchi, R.1    Tanaka, M.2    Yano, A.3
  • 7
    • 84876086929 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes predict response to neoadjuvant chemotherapy in breast cancer patients
    • (Mar);
    • Lee HJ, Seo JY, Ahn JH, Ahn SH, Gong G. Tumor-associated lymphocytes predict response to neoadjuvant chemotherapy in breast cancer patients. J Breast Cancer 2013 (Mar); 16(1): 32–9.
    • (2013) J Breast Cancer , vol.16 , Issue.1 , pp. 32-39
    • Lee, H.J.1    Seo, J.Y.2    Ahn, J.H.3    Ahn, S.H.4    Gong, G.5
  • 8
    • 84875722651 scopus 로고    scopus 로고
    • Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98
    • (Mar 1);
    • Loi S, Sirtaine N, Piette F et al. Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98. J Clin Oncol 2013 (Mar 1); 31: 860–7.
    • (2013) J Clin Oncol , vol.31 , pp. 860-867
    • Loi, S.1    Sirtaine, N.2    Piette, F.3
  • 9
    • 84907198355 scopus 로고    scopus 로고
    • Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199
    • (Jul 28);, PubMed PMID 25071121. Epub 2014/07/30. Eng.
    • Adams S, Gray RJ, Demaria S et al. Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199. J Clin Oncol 2014 (Jul 28); 32: 2959–66. PubMed PMID: 25071121. Epub 2014/07/30. Eng.
    • (2014) J Clin Oncol , vol.32 , pp. 2959-2966
    • Adams, S.1    Gray, R.J.2    Demaria, S.3
  • 10
    • 84927138902 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers
    • (Dec 22);, PubMed PMID 25534375. Epub 2014/12/24. Eng.
    • Denkert C, von Minckwitz G, Brase JC et al. Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers. J Clin Oncol 2014 (Dec 22); 33: 983–91. PubMed PMID: 25534375. Epub 2014/12/24. Eng.
    • (2014) J Clin Oncol , vol.33 , pp. 983-991
    • Denkert, C.1    von Minckwitz, G.2    Brase, J.C.3
  • 11
    • 84905178989 scopus 로고    scopus 로고
    • Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial
    • (Aug);
    • Loi S, Michiels S, Salgado R et al. Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial. Ann Oncol 2014 (Aug); 25: 1544–50.
    • (2014) Ann Oncol , vol.25 , pp. 1544-1550
    • Loi, S.1    Michiels, S.2    Salgado, R.3
  • 12
    • 84925273291 scopus 로고    scopus 로고
    • Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the north central cancer treatment group N9831 adjuvant trastuzumab trial
    • (Jan 20);, PubMed PMID 25605861. Epub 2015/01/22. Eng.
    • Perez EA, Thompson EA, Ballman KV et al. Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the north central cancer treatment group N9831 adjuvant trastuzumab trial. J Clin Oncol 2015 (Jan 20); 33: 701–8. PubMed PMID: 25605861. Epub 2015/01/22. Eng.
    • (2015) J Clin Oncol , vol.33 , pp. 701-708
    • Perez, E.A.1    Thompson, E.A.2    Ballman, K.V.3
  • 13
    • 30144436959 scopus 로고    scopus 로고
    • Phenotyping of lymphocytes expressing regulatory and effector markers in infiltrating ductal carcinoma of the breast
    • (Feb 15);
    • Leong PP, Mohammad R, Ibrahim N et al. Phenotyping of lymphocytes expressing regulatory and effector markers in infiltrating ductal carcinoma of the breast. Immunol Lett 2006 (Feb 15); 102: 229–36.
    • (2006) Immunol Lett , vol.102 , pp. 229-236
    • Leong, P.P.1    Mohammad, R.2    Ibrahim, N.3
  • 14
    • 84911898296 scopus 로고    scopus 로고
    • Tumor-infiltrating CD8+ and FOXP3+ lymphocytes in triple-negative breast cancer: its correlation with pathological complete response to neoadjuvant chemotherapy
    • (Dec);
    • Miyashita M, Sasano H, Tamaki K et al. Tumor-infiltrating CD8+ and FOXP3+ lymphocytes in triple-negative breast cancer: its correlation with pathological complete response to neoadjuvant chemotherapy. Breast Cancer Res Treat 2014 (Dec); 148: 525–34.
    • (2014) Breast Cancer Res Treat , vol.148 , pp. 525-534
    • Miyashita, M.1    Sasano, H.2    Tamaki, K.3
  • 15
    • 84896872171 scopus 로고    scopus 로고
    • Prognostic value of tumor-infiltrating lymphocytes on residual disease after primary chemotherapy for triple-negative breast cancer: a retrospective multicenter study
    • (Mar);
    • Dieci MV, Criscitiello C, Goubar A et al. Prognostic value of tumor-infiltrating lymphocytes on residual disease after primary chemotherapy for triple-negative breast cancer: a retrospective multicenter study. Ann Oncol 2014 (Mar); 25: 611–8.
    • (2014) Ann Oncol , vol.25 , pp. 611-618
    • Dieci, M.V.1    Criscitiello, C.2    Goubar, A.3
  • 16
    • 84963740728 scopus 로고    scopus 로고
    • Adjuvant endocrine therapy for women with hormone receptor-positive breast cancer: American Society of Clinical Oncology Clinical Practice Guideline Update on Ovarian Suppression
    • (Feb 16);, PubMed PMID 26884586.
    • Burstein HJ, Lacchetti C, Anderson H et al. Adjuvant endocrine therapy for women with hormone receptor-positive breast cancer: American Society of Clinical Oncology Clinical Practice Guideline Update on Ovarian Suppression. J Clin Oncol 2016 (Feb 16); 34: 1689–701. PubMed PMID: 26884586.
    • (2016) J Clin Oncol , vol.34 , pp. 1689-1701
    • Burstein, H.J.1    Lacchetti, C.2    Anderson, H.3
  • 17
    • 84884413571 scopus 로고    scopus 로고
    • Metastatic triple-negative breast cancers at first relapse have fewer tumor-infiltrating lymphocytes than their matched primary breast tumors: a pilot study
    • (Oct);
    • Cimino-Mathews A, Ye X, Meeker A, Argani P, Emens LA. Metastatic triple-negative breast cancers at first relapse have fewer tumor-infiltrating lymphocytes than their matched primary breast tumors: a pilot study. Hum Pathol 2013 (Oct); 44: 2055–63.
    • (2013) Hum Pathol , vol.44 , pp. 2055-2063
    • Cimino-Mathews, A.1    Ye, X.2    Meeker, A.3    Argani, P.4    Emens, L.A.5
  • 18
    • 84976544263 scopus 로고    scopus 로고
    • Similar lymphocytic infiltration pattern in primary breast cancer and their corresponding distant metastases
    • (Jun);
    • Sobottka B, Pestalozzi B, Fink D, Moch H, Varga Z. Similar lymphocytic infiltration pattern in primary breast cancer and their corresponding distant metastases. Oncoimmunology 2016 (Jun); 5(6): e1153208.
    • (2016) Oncoimmunology , vol.5 , Issue.6
    • Sobottka, B.1    Pestalozzi, B.2    Fink, D.3    Moch, H.4    Varga, Z.5
  • 19
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: from immunosurveillance to tumor escape
    • (Nov);
    • Dunn GP, Bruce AT, Ikeda H, Old LJ, Schreiber RD. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol 2002 (Nov); 3: 991–8.
    • (2002) Nat Immunol , vol.3 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3    Old, L.J.4    Schreiber, R.D.5
  • 20
    • 34047220868 scopus 로고    scopus 로고
    • Cancer immunoediting from immune surveillance to immune escape
    • (May);
    • Kim R, Emi M, Tanabe K. Cancer immunoediting from immune surveillance to immune escape. Immunology 2007 (May); 121(1): 1–14.
    • (2007) Immunology , vol.121 , Issue.1 , pp. 1-14
    • Kim, R.1    Emi, M.2    Tanabe, K.3
  • 21
    • 84922393869 scopus 로고    scopus 로고
    • Maastricht Delphi consensus on event definitions for classification of recurrence in breast cancer research
    • (Dec);, PubMed PMID 25381395. Epub 2014/11/09. Eng.
    • Moossdorff M, van Roozendaal LM, Strobbe LJ et al. Maastricht Delphi consensus on event definitions for classification of recurrence in breast cancer research. J Natl Cancer Inst 2014 (Dec); 106(12): dju288. PubMed PMID: 25381395. Epub 2014/11/09. Eng.
    • (2014) J Natl Cancer Inst , vol.106 , Issue.12 , pp. dju288
    • Moossdorff, M.1    van Roozendaal, L.M.2    Strobbe, L.J.3
  • 22
    • 79960980007 scopus 로고    scopus 로고
    • Strategies for subtypes–dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011
    • (Aug);
    • Goldhirsch A, Wood WC, Coates AS, Gelber RD, Thurlimann B, Senn HJ. Strategies for subtypes–dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011. Ann Oncol 2011 (Aug); 22: 1736–47.
    • (2011) Ann Oncol , vol.22 , pp. 1736-1747
    • Goldhirsch, A.1    Wood, W.C.2    Coates, A.S.3    Gelber, R.D.4    Thurlimann, B.5    Senn, H.J.6
  • 23
    • 84924076132 scopus 로고    scopus 로고
    • The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014
    • (Feb);
    • Salgado R, Denkert C, Demaria S et al. The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014. Ann Oncol 2015 (Feb); 26: 259–71.
    • (2015) Ann Oncol , vol.26 , pp. 259-271
    • Salgado, R.1    Denkert, C.2    Demaria, S.3
  • 24
    • 84857568955 scopus 로고    scopus 로고
    • Prospective study evaluating the impact of tissue confirmation of metastatic disease in patients with breast cancer
    • (Feb 20);
    • Amir E, Miller N, Geddie W et al. Prospective study evaluating the impact of tissue confirmation of metastatic disease in patients with breast cancer. J Clin Oncol 2012 (Feb 20); 30: 587–92.
    • (2012) J Clin Oncol , vol.30 , pp. 587-592
    • Amir, E.1    Miller, N.2    Geddie, W.3
  • 25
    • 69849090104 scopus 로고    scopus 로고
    • Does confirmatory tumor biopsy alter the management of breast cancer patients with distant metastases?
    • (Sep);
    • Simmons C, Miller N, Geddie W et al. Does confirmatory tumor biopsy alter the management of breast cancer patients with distant metastases? Ann Oncol 2009 (Sep); 20: 1499–504.
    • (2009) Ann Oncol , vol.20 , pp. 1499-1504
    • Simmons, C.1    Miller, N.2    Geddie, W.3
  • 26
    • 78049459908 scopus 로고    scopus 로고
    • Prospective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS)
    • Thompson AM, Jordan LB, Quinlan P et al. Prospective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS). Breast Cancer Res 2010; 12(6): R92.
    • (2010) Breast Cancer Res , vol.12 , Issue.6 , pp. R92
    • Thompson, A.M.1    Jordan, L.B.2    Quinlan, P.3
  • 27
    • 84863116159 scopus 로고    scopus 로고
    • Loss of human epidermal growth factor receptor 2 (HER2) expression in metastatic sites of HER2-overexpressing primary breast tumors
    • (Feb 20);
    • Niikura N, Liu J, Hayashi N et al. Loss of human epidermal growth factor receptor 2 (HER2) expression in metastatic sites of HER2-overexpressing primary breast tumors. J Clin Oncol 2012 (Feb 20); 30: 593–9.
    • (2012) J Clin Oncol , vol.30 , pp. 593-599
    • Niikura, N.1    Liu, J.2    Hayashi, N.3
  • 28
    • 84907210556 scopus 로고    scopus 로고
    • Host antitumor immunity plays a role in the survival of patients with newly diagnosed triple-negative breast cancer
    • (Sep 20);
    • Loi S, MacCallum P. Host antitumor immunity plays a role in the survival of patients with newly diagnosed triple-negative breast cancer. J Clin Oncol 2014 (Sep 20); 32: 2935–7.
    • (2014) J Clin Oncol , vol.32 , pp. 2935-2937
    • Loi, S.1    MacCallum, P.2
  • 29
    • 84944937210 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
    • (Oct 22);
    • Borghaei H, Paz-Ares L, Horn L et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med 2015 (Oct 22); 373: 1627–39.
    • (2015) N Engl J Med , vol.373 , pp. 1627-1639
    • Borghaei, H.1    Paz-Ares, L.2    Horn, L.3
  • 30
    • 84931083080 scopus 로고    scopus 로고
    • Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
    • (Apr);
    • Weber JS, D'Angelo SP, Minor D et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. Lancet Oncol 2015 (Apr); 16: 375–84.
    • (2015) Lancet Oncol , vol.16 , pp. 375-384
    • Weber, J.S.1    D'Angelo, S.P.2    Minor, D.3
  • 31
    • 84946607195 scopus 로고    scopus 로고
    • Nivolumab versus everolimus in advanced renal-cell carcinoma
    • (Nov 5);
    • Motzer RJ, Escudier B, McDermott DF et al. Nivolumab versus everolimus in advanced renal-cell carcinoma. N Engl J Med 2015 (Nov 5); 373: 1803–13.
    • (2015) N Engl J Med , vol.373 , pp. 1803-1813
    • Motzer, R.J.1    Escudier, B.2    McDermott, D.F.3
  • 32
    • 84928774156 scopus 로고    scopus 로고
    • The future of immune checkpoint therapy
    • (Apr 3);
    • Sharma P, Allison JP. The future of immune checkpoint therapy. Science 2015 (Apr 3); 348(6230): 56–61.
    • (2015) Science , vol.348 , Issue.6230 , pp. 56-61
    • Sharma, P.1    Allison, J.P.2
  • 33
    • 84956701460 scopus 로고    scopus 로고
    • Guidance on cancer immunotherapy development in early-phase clinical studies
    • (Dec);, PubMed PMID 26767933. Pubmed Central PMCID 4714668. Epub 2016/01/16. eng.
    • Arato T, Daimon T, Heike Y et al. Guidance on cancer immunotherapy development in early-phase clinical studies. Cancer Sci 2015 (Dec);106(12):1761–71. PubMed PMID: 26767933. Pubmed Central PMCID: 4714668. Epub 2016/01/16. eng.
    • (2015) Cancer Sci , vol.106 , Issue.12 , pp. 1761-1771
    • Arato, T.1    Daimon, T.2    Heike, Y.3
  • 34
    • 84893362995 scopus 로고    scopus 로고
    • Incorporating immune-checkpoint inhibitors into systemic therapy of NSCLC
    • Champiat S, Ileana E, Giaccone G et al. Incorporating immune-checkpoint inhibitors into systemic therapy of NSCLC. J Thorac Oncol 2014; 9: 144–53.
    • (2014) J Thorac Oncol , vol.9 , pp. 144-153
    • Champiat, S.1    Ileana, E.2    Giaccone, G.3
  • 35
    • 84982889739 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes and associations with pathological complete response and event-free survival in HER2-positive early-stage breast cancer treated with lapatinib and trastuzumab: a secondary analysis of the NeoALTTO trial
    • (Jul);
    • Salgado R, Denkert C, Campbell C et al. Tumor-infiltrating lymphocytes and associations with pathological complete response and event-free survival in HER2-positive early-stage breast cancer treated with lapatinib and trastuzumab: a secondary analysis of the NeoALTTO trial. JAMA Oncol 2015 (Jul); 1: 448–54.
    • (2015) JAMA Oncol , vol.1 , pp. 448-454
    • Salgado, R.1    Denkert, C.2    Campbell, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.