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Volumn 148, Issue 3, 2014, Pages 525-534

Tumor-infiltrating CD8+ and FOXP3+ lymphocytes in triple-negative breast cancer: its correlation with pathological complete response to neoadjuvant chemotherapy

Author keywords

CD8; Chemo sensitivity; FOXP3; Ki 67; pCR; Triple negative breast cancer

Indexed keywords

ANTHRACYCLINE; CD31 ANTIGEN; CD8 ANTIGEN; CELL PROTEIN; CYTOKERATIN 5; CYTOKERATIN 6; EPIDERMAL GROWTH FACTOR RECEPTOR; KI 67 ANTIGEN; TAXANE DERIVATIVE; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; VASOHIBIN 1; BRIDGED COMPOUND; ESTROGEN RECEPTOR; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; TAXANE; TAXOID; TUMOR MARKER;

EID: 84911898296     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-3197-y     Document Type: Article
Times cited : (78)

References (38)
  • 1
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • COI: 1:CAS:528:DC%2BD3cXmt1CnsLw%3D, PID: 10963602
    • Perou CM, Sorlie T, Eisen MB et al (2000) Molecular portraits of human breast tumours. Nature 406:747–752
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 2
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • COI: 1:CAS:528:DC%2BD3MXntVGmsbo%3D, PID: 11553815
    • Sorlie T, Perou CM, Tibshirani R et al (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98:10869–10874
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3
  • 3
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • COI: 1:CAS:528:DC%2BD3sXlsFGntLk%3D, PID: 12829800
    • Sorlie T, Tibshirani R, Parker J et al (2003) Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 100:8418–8423
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8418-8423
    • Sorlie, T.1    Tibshirani, R.2    Parker, J.3
  • 4
    • 84904188903 scopus 로고    scopus 로고
    • Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis
    • PID: 24529560
    • Cortazar P, Zhang L, Untch M et al (2014) Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis. Lancet 384:164–172
    • (2014) Lancet , vol.384 , pp. 164-172
    • Cortazar, P.1    Zhang, L.2    Untch, M.3
  • 5
    • 41649102048 scopus 로고    scopus 로고
    • Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
    • PID: 18250347
    • Liedtke C, Mazouni C, Hess KR et al (2008) Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol 26:1275–1281
    • (2008) J Clin Oncol , vol.26 , pp. 1275-1281
    • Liedtke, C.1    Mazouni, C.2    Hess, K.R.3
  • 6
    • 75149128222 scopus 로고    scopus 로고
    • Identification of biology-based breast cancer types with distinct predictive and prognostic features: role of steroid hormone and HER2 receptor expression in patients treated with neoadjuvant anthracycline/taxane-based chemotherapy
    • PID: 19758440
    • Darb-Esfahani S, Loibl S, Muller BM et al (2009) Identification of biology-based breast cancer types with distinct predictive and prognostic features: role of steroid hormone and HER2 receptor expression in patients treated with neoadjuvant anthracycline/taxane-based chemotherapy. Breast Cancer Res 11:R69
    • (2009) Breast Cancer Res , vol.11 , pp. R69
    • Darb-Esfahani, S.1    Loibl, S.2    Muller, B.M.3
  • 7
    • 84887042578 scopus 로고    scopus 로고
    • Ki67 levels as predictive and prognostic parameters in pretherapeutic breast cancer core biopsies: a translational investigation in the neoadjuvant GeparTrio trial
    • COI: 1:STN:280:DC%2BC3sbitVWlsg%3D%3D, PID: 23970015
    • Denkert C, Loibl S, Muller BM et al (2013) Ki67 levels as predictive and prognostic parameters in pretherapeutic breast cancer core biopsies: a translational investigation in the neoadjuvant GeparTrio trial. Ann Oncol 24:2786–2793
    • (2013) Ann Oncol , vol.24 , pp. 2786-2793
    • Denkert, C.1    Loibl, S.2    Muller, B.M.3
  • 8
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • COI: 1:CAS:528:DC%2BC3MXovVKgu78%3D, PID: 21633166
    • Lehmann BD, Bauer JA, Chen X et al (2011) Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Investig 121:2750–2767
    • (2011) J Clin Investig , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3
  • 9
    • 84886412350 scopus 로고    scopus 로고
    • Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes
    • COI: 1:CAS:528:DC%2BC3sXhsFynsL7P, PID: 23948975
    • Masuda H, Baggerly KA, Wang Y et al (2013) Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes. Clin Cancer Res 19:5533–5540
    • (2013) Clin Cancer Res , vol.19 , pp. 5533-5540
    • Masuda, H.1    Baggerly, K.A.2    Wang, Y.3
  • 10
    • 34948820602 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
    • COI: 1:CAS:528:DC%2BD2sXhtVSgtr3E, PID: 17704786
    • Apetoh L, Ghiringhelli F, Tesniere A et al (2007) Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 13:1050–1059
    • (2007) Nat Med , vol.13 , pp. 1050-1059
    • Apetoh, L.1    Ghiringhelli, F.2    Tesniere, A.3
  • 11
    • 84871949633 scopus 로고    scopus 로고
    • Molecular pathways: involvement of immune pathways in the therapeutic response and outcome in breast cancer
    • COI: 1:CAS:528:DC%2BC3sXktFGltg%3D%3D, PID: 23258741
    • Andre F, Dieci MV, Dubsky P et al (2013) Molecular pathways: involvement of immune pathways in the therapeutic response and outcome in breast cancer. Clin Cancer Res 19:28–33
    • (2013) Clin Cancer Res , vol.19 , pp. 28-33
    • Andre, F.1    Dieci, M.V.2    Dubsky, P.3
  • 12
    • 85027940310 scopus 로고    scopus 로고
    • CD8(+) cytotoxic T cell and FOXP3(+) regulatory T cell infiltration in relation to breast cancer survival and molecular subtypes
    • COI: 1:CAS:528:DC%2BC3MXht1yktL3J, PID: 21717105
    • Liu F, Lang R, Zhao J et al (2011) CD8(+) cytotoxic T cell and FOXP3(+) regulatory T cell infiltration in relation to breast cancer survival and molecular subtypes. Breast Cancer Res Treat 130:645–655
    • (2011) Breast Cancer Res Treat , vol.130 , pp. 645-655
    • Liu, F.1    Lang, R.2    Zhao, J.3
  • 13
    • 84862784272 scopus 로고    scopus 로고
    • CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer
    • COI: 1:CAS:528:DC%2BC38XmtFGisbs%3D, PID: 22420471
    • Liu S, Lachapelle J, Leung S, Gao D, Foulkes WD, Nielsen TO (2012) CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer. Breast Cancer Res 14:R48
    • (2012) Breast Cancer Res , vol.14 , pp. R48
    • Liu, S.1    Lachapelle, J.2    Leung, S.3    Gao, D.4    Foulkes, W.D.5    Nielsen, T.O.6
  • 14
    • 84905186948 scopus 로고    scopus 로고
    • Association between CD8+ T-cell infiltration and breast cancer survival in 12 439 patients
    • COI: 1:STN:280:DC%2BC2cfhtVChug%3D%3D, PID: 24915873
    • Ali HR, Provenzano E, Dawson SJ et al (2014) Association between CD8+ T-cell infiltration and breast cancer survival in 12 439 patients. Ann Oncol 25:1536–1543
    • (2014) Ann Oncol , vol.25 , pp. 1536-1543
    • Ali, H.R.1    Provenzano, E.2    Dawson, S.J.3
  • 15
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • COI: 1:CAS:528:DC%2BD38XmsF2ns7k%3D, PID: 12193750
    • Liyanage UK, Moore TT, Joo HG et al (2002) Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol 169:2756–2761
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.G.3
  • 16
    • 3142737258 scopus 로고    scopus 로고
    • Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
    • COI: 1:CAS:528:DC%2BD2cXlsVGhs70%3D, PID: 15240741
    • Viguier M, Lemaitre F, Verola O et al (2004) Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J Immunol 173:1444–1453
    • (2004) J Immunol , vol.173 , pp. 1444-1453
    • Viguier, M.1    Lemaitre, F.2    Verola, O.3
  • 17
    • 79954815112 scopus 로고    scopus 로고
    • An evaluation of the clinical significance of FOXP3+ infiltrating cells in human breast cancer
    • COI: 1:CAS:528:DC%2BC3MXksFegtrs%3D, PID: 20556505
    • Mahmoud SM, Paish EC, Powe DG et al (2011) An evaluation of the clinical significance of FOXP3+ infiltrating cells in human breast cancer. Breast Cancer Res Treat 127:99–108
    • (2011) Breast Cancer Res Treat , vol.127 , pp. 99-108
    • Mahmoud, S.M.1    Paish, E.C.2    Powe, D.G.3
  • 18
    • 84867849831 scopus 로고    scopus 로고
    • Intratumoral regulatory T cells as an independent predictive factor for pathological complete response to neoadjuvant paclitaxel followed by 5-FU/epirubicin/cyclophosphamide in breast cancer patients
    • COI: 1:CAS:528:DC%2BC38XhsFamtLfK, PID: 22986814
    • Oda N, Shimazu K, Naoi Y et al (2012) Intratumoral regulatory T cells as an independent predictive factor for pathological complete response to neoadjuvant paclitaxel followed by 5-FU/epirubicin/cyclophosphamide in breast cancer patients. Breast Cancer Res Treat 136:107–116
    • (2012) Breast Cancer Res Treat , vol.136 , pp. 107-116
    • Oda, N.1    Shimazu, K.2    Naoi, Y.3
  • 19
    • 84872608638 scopus 로고    scopus 로고
    • Tumour-infiltrating FOXP3+ lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer
    • COI: 1:CAS:528:DC%2BC3sXhtFCmtrg%3D, PID: 23169287
    • West NR, Kost SE, Martin SD et al (2013) Tumour-infiltrating FOXP3+ lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer. Br J Cancer 108:155–162
    • (2013) Br J Cancer , vol.108 , pp. 155-162
    • West, N.R.1    Kost, S.E.2    Martin, S.D.3
  • 20
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis—correlation in invasive breast carcinoma
    • COI: 1:STN:280:DyaK3M%2FnsVWquw%3D%3D, PID: 1701519
    • Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumor angiogenesis and metastasis—correlation in invasive breast carcinoma. N Engl J Med 324:1–8
    • (1991) N Engl J Med , vol.324 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 21
    • 0027043136 scopus 로고
    • Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma
    • COI: 1:STN:280:DyaK3s%2FpsFWhtA%3D%3D, PID: 1281237
    • Weidner N, Folkman J, Pozza F et al (1992) Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 84:1875–1887
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1875-1887
    • Weidner, N.1    Folkman, J.2    Pozza, F.3
  • 22
    • 0029156024 scopus 로고
    • Prognostic value of intratumoral microvessel density, a measure of tumor angiogenesis, in node-negative breast carcinoma—results of a multiparametric study
    • COI: 1:STN:280:DyaK28%2FkvFyjtg%3D%3D, PID: 8534868
    • Bevilacqua P, Barbareschi M, Verderio P et al (1995) Prognostic value of intratumoral microvessel density, a measure of tumor angiogenesis, in node-negative breast carcinoma—results of a multiparametric study. Breast Cancer Res Treat 36:205–217
    • (1995) Breast Cancer Res Treat , vol.36 , pp. 205-217
    • Bevilacqua, P.1    Barbareschi, M.2    Verderio, P.3
  • 23
    • 84863255475 scopus 로고    scopus 로고
    • Effects of estrogen depletion on angiogenesis in estrogen-receptor-positive breast carcinoma—an immunohistochemical study of vasohibin-1 and CD31 with correlation to pathobiological response of the patients in neoadjuvant aromatase inhibitor therapy
    • COI: 1:CAS:528:DC%2BC38XivFOntLY%3D, PID: 22309693
    • Chan MS, Wang L, Chanplakorn N et al (2012) Effects of estrogen depletion on angiogenesis in estrogen-receptor-positive breast carcinoma—an immunohistochemical study of vasohibin-1 and CD31 with correlation to pathobiological response of the patients in neoadjuvant aromatase inhibitor therapy. Expert Opin Ther Targets 16(Suppl 1):S69–S78
    • (2012) Expert Opin Ther Targets , vol.16 , pp. S69-S78
    • Chan, M.S.1    Wang, L.2    Chanplakorn, N.3
  • 24
    • 34250005419 scopus 로고    scopus 로고
    • Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients
    • PID: 17570208
    • Fu J, Xu D, Liu Z et al (2007) Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients. Gastroenterology 132:2328–2339
    • (2007) Gastroenterology , vol.132 , pp. 2328-2339
    • Fu, J.1    Xu, D.2    Liu, Z.3
  • 25
    • 79956329617 scopus 로고    scopus 로고
    • Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer
    • PID: 21483002
    • Mahmoud SM, Paish EC, Powe DG et al (2011) Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer. J Clin Oncol 29:1949–1955
    • (2011) J Clin Oncol , vol.29 , pp. 1949-1955
    • Mahmoud, S.M.1    Paish, E.C.2    Powe, D.G.3
  • 26
    • 58149313660 scopus 로고    scopus 로고
    • Vasohibin-1 in human breast carcinoma: a potential negative feedback regulator of angiogenesis
    • COI: 1:CAS:528:DC%2BD1MXhtlGns74%3D, PID: 19037993
    • Tamaki K, Moriya T, Sato Y et al (2009) Vasohibin-1 in human breast carcinoma: a potential negative feedback regulator of angiogenesis. Cancer Sci 100:88–94
    • (2009) Cancer Sci , vol.100 , pp. 88-94
    • Tamaki, K.1    Moriya, T.2    Sato, Y.3
  • 27
    • 77956177822 scopus 로고    scopus 로고
    • Vasohibin-1 as a potential predictor of aggressive behavior of ductal carcinoma in situ of the breast
    • COI: 1:CAS:528:DC%2BC3cXkvFKitrg%3D, PID: 20704578
    • Tamaki K, Sasano H, Maruo Y et al (2010) Vasohibin-1 as a potential predictor of aggressive behavior of ductal carcinoma in situ of the breast. Cancer Sci 101:1051–1058
    • (2010) Cancer Sci , vol.101 , pp. 1051-1058
    • Tamaki, K.1    Sasano, H.2    Maruo, Y.3
  • 28
    • 33847147313 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • COI: 1:CAS:528:DC%2BD2sXht1ejs7Y%3D, PID: 17159189
    • Wolff AC, Hammond ME, Schwartz JN et al (2007) American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 25:118–145
    • (2007) J Clin Oncol , vol.25 , pp. 118-145
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3
  • 29
    • 27244443082 scopus 로고    scopus 로고
    • Proliferation marker Ki-67 in early breast cancer
    • COI: 1:CAS:528:DC%2BD2MXhtFCrsbfK, PID: 16192605
    • Urruticoechea A, Smith IE, Dowsett M (2005) Proliferation marker Ki-67 in early breast cancer. J Clin Oncol 23:7212–7220
    • (2005) J Clin Oncol , vol.23 , pp. 7212-7220
    • Urruticoechea, A.1    Smith, I.E.2    Dowsett, M.3
  • 30
    • 34248595234 scopus 로고    scopus 로고
    • Ki-67 as prognostic marker in early breast cancer: a meta-analysis of published studies involving 12,155 patients
    • PID: 17453008
    • de Azambuja E, Cardoso F, de Castro Jr G et al (2007) Ki-67 as prognostic marker in early breast cancer: a meta-analysis of published studies involving 12,155 patients. Br J Cancer 96:1504–1513
    • (2007) Br J Cancer , vol.96 , pp. 1504-1513
    • de Azambuja, E.1    Cardoso, F.2    de Castro, G.3
  • 31
    • 35348981836 scopus 로고    scopus 로고
    • Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas)
    • COI: 1:CAS:528:DC%2BD2sXhtFOksbzK, PID: 17885672
    • Lerma E, Peiro G, Ramon T et al (2007) Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas). Mod Pathol 20:1200–1207
    • (2007) Mod Pathol , vol.20 , pp. 1200-1207
    • Lerma, E.1    Peiro, G.2    Ramon, T.3
  • 32
    • 45149094267 scopus 로고    scopus 로고
    • Basal-like breast cancer: a critical review
    • PID: 18487574
    • Rakha EA, Reis-Filho JS, Ellis IO (2008) Basal-like breast cancer: a critical review. J Clin Oncol 26:2568–2581
    • (2008) J Clin Oncol , vol.26 , pp. 2568-2581
    • Rakha, E.A.1    Reis-Filho, J.S.2    Ellis, I.O.3
  • 33
    • 20144389441 scopus 로고    scopus 로고
    • Gene expression profiling identifies molecular subtypes of inflammatory breast cancer
    • COI: 1:CAS:528:DC%2BD2MXisFGgurc%3D, PID: 15781628
    • Bertucci F, Finetti P, Rougemont J et al (2005) Gene expression profiling identifies molecular subtypes of inflammatory breast cancer. Cancer Res 65:2170–2178
    • (2005) Cancer Res , vol.65 , pp. 2170-2178
    • Bertucci, F.1    Finetti, P.2    Rougemont, J.3
  • 34
    • 33646390671 scopus 로고    scopus 로고
    • Gene expression profiling shows medullary breast cancer is a subgroup of basal breast cancers
    • COI: 1:CAS:528:DC%2BD28XjvF2ksb4%3D, PID: 16651414
    • Bertucci F, Finetti P, Cervera N et al (2006) Gene expression profiling shows medullary breast cancer is a subgroup of basal breast cancers. Cancer Res 66:4636–4644
    • (2006) Cancer Res , vol.66 , pp. 4636-4644
    • Bertucci, F.1    Finetti, P.2    Cervera, N.3
  • 35
    • 42249115188 scopus 로고    scopus 로고
    • Pathologic complete response to neoadjuvant chemotherapy of breast carcinoma is associated with the disappearance of tumor-infiltrating foxp3+ regulatory T cells
    • COI: 1:CAS:528:DC%2BD1cXkvFGmtbs%3D, PID: 18413832
    • Ladoire S, Arnould L, Apetoh L et al (2008) Pathologic complete response to neoadjuvant chemotherapy of breast carcinoma is associated with the disappearance of tumor-infiltrating foxp3+ regulatory T cells. Clin Cancer Res 14:2413–2420
    • (2008) Clin Cancer Res , vol.14 , pp. 2413-2420
    • Ladoire, S.1    Arnould, L.2    Apetoh, L.3
  • 36
    • 84883325272 scopus 로고    scopus 로고
    • Personalized the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013
    • COI: 1:STN:280:DC%2BC3sfmvFajuw%3D%3D, PID: 23917950
    • Goldhirsch A, Winer EP, Coates AS et al (2013) Personalized the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013. Ann Oncol 24:2206–2223
    • (2013) Ann Oncol , vol.24 , pp. 2206-2223
    • Goldhirsch, A.1    Winer, E.P.2    Coates, A.S.3
  • 37
    • 77957350018 scopus 로고    scopus 로고
    • Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression
    • COI: 1:CAS:528:DC%2BC3cXht1akt7vP, PID: 20841473
    • Doedens AL, Stockmann C, Rubinstein MP et al (2010) Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Res 70:7465–7475
    • (2010) Cancer Res , vol.70 , pp. 7465-7475
    • Doedens, A.L.1    Stockmann, C.2    Rubinstein, M.P.3
  • 38
    • 79952281184 scopus 로고    scopus 로고
    • Angiogenesis and immunity: a bidirectional link potentially relevant for the monitoring of antiangiogenic therapy and the development of novel therapeutic combination with immunotherapy
    • COI: 1:CAS:528:DC%2BC3MXitlKltL8%3D, PID: 21249423
    • Tartour E, Pere H, Maillere B et al (2011) Angiogenesis and immunity: a bidirectional link potentially relevant for the monitoring of antiangiogenic therapy and the development of novel therapeutic combination with immunotherapy. Cancer Metastasis Rev 30:83–95
    • (2011) Cancer Metastasis Rev , vol.30 , pp. 83-95
    • Tartour, E.1    Pere, H.2    Maillere, B.3


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