메뉴 건너뛰기




Volumn 69, Issue 1, 2017, Pages 148-160

Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; AUTOANTIBODY; CHOLESTEROL ESTER; DOUBLE STRANDED DNA ANTIBODY; GAMMA INTERFERON; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 17; INTERLEUKIN 2; JANUS KINASE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; STAT1 PROTEIN; TOFACITINIB; TUMOR NECROSIS FACTOR; PIPERIDINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE;

EID: 85007309278     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39818     Document Type: Article
Times cited : (178)

References (54)
  • 1
    • 84875461762 scopus 로고    scopus 로고
    • Mechanisms of disease for the clinician: systemic lupus erythematosus
    • Frieri M. Mechanisms of disease for the clinician: systemic lupus erythematosus. Ann Allergy Asthma Immunol 2013;110:228–32.
    • (2013) Ann Allergy Asthma Immunol , vol.110 , pp. 228-232
    • Frieri, M.1
  • 2
    • 82955233986 scopus 로고    scopus 로고
    • Neutrophils in the pathogenesis and manifestations of SLE
    • Kaplan MJ. Neutrophils in the pathogenesis and manifestations of SLE. Nat Rev Rheumatol 2011;7:691–9.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 691-699
    • Kaplan, M.J.1
  • 3
    • 77953555514 scopus 로고    scopus 로고
    • Cytokines as therapeutic targets in SLE
    • Rönnblom L, Elkon KB. Cytokines as therapeutic targets in SLE. Nat Rev Rheumatol 2010;6:339–47.
    • (2010) Nat Rev Rheumatol , vol.6 , pp. 339-347
    • Rönnblom, L.1    Elkon, K.B.2
  • 4
    • 0142086891 scopus 로고    scopus 로고
    • Abnormal expression of chemokine receptors on T-cells from patients with systemic lupus erythematosus
    • Eriksson C, Eneslatt K, Ivanoff J, Rantapää-Dahlqvist S, Sundqvist KG. Abnormal expression of chemokine receptors on T-cells from patients with systemic lupus erythematosus. Lupus 2003;12:766–74.
    • (2003) Lupus , vol.12 , pp. 766-774
    • Eriksson, C.1    Eneslatt, K.2    Ivanoff, J.3    Rantapää-Dahlqvist, S.4    Sundqvist, K.G.5
  • 5
    • 31144436101 scopus 로고    scopus 로고
    • Raised plasma concentration and ex vivo production of inflammatory chemokines in patients with systemic lupus erythematosus
    • Lit LC, Wong CK, Tam LS, Li EK, Lam CW. Raised plasma concentration and ex vivo production of inflammatory chemokines in patients with systemic lupus erythematosus. Ann Rheum Dis 2006;65:209–15.
    • (2006) Ann Rheum Dis , vol.65 , pp. 209-215
    • Lit, L.C.1    Wong, C.K.2    Tam, L.S.3    Li, E.K.4    Lam, C.W.5
  • 6
    • 84903453743 scopus 로고    scopus 로고
    • Proinflammatory adaptive cytokine and shed tumor necrosis factor receptor levels are elevated preceding systemic lupus erythematosus disease flare
    • Munroe ME, Vista ES, Guthridge JM, Thompson LF, Merrill JT, James JA. Proinflammatory adaptive cytokine and shed tumor necrosis factor receptor levels are elevated preceding systemic lupus erythematosus disease flare. Arthritis Rheumatol 2014;66:1888–99.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 1888-1899
    • Munroe, M.E.1    Vista, E.S.2    Guthridge, J.M.3    Thompson, L.F.4    Merrill, J.T.5    James, J.A.6
  • 7
    • 84921325776 scopus 로고    scopus 로고
    • Targeting of type I interferon in systemic autoimmune diseases
    • Crow MK, Olferiev M, Kirou KA. Targeting of type I interferon in systemic autoimmune diseases. Transl Res 2015;165:296–305.
    • (2015) Transl Res , vol.165 , pp. 296-305
    • Crow, M.K.1    Olferiev, M.2    Kirou, K.A.3
  • 8
    • 0034761724 scopus 로고    scopus 로고
    • Traditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosus
    • Esdaile JM, Abrahamowicz M, Grodzicky T, Li Y, Panaritis C, du Berger R, et al. Traditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosus. Arthritis Rheum 2001;44:2331–7.
    • (2001) Arthritis Rheum , vol.44 , pp. 2331-2337
    • Esdaile, J.M.1    Abrahamowicz, M.2    Grodzicky, T.3    Li, Y.4    Panaritis, C.5    du Berger, R.6
  • 9
    • 0141891339 scopus 로고    scopus 로고
    • Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients
    • Cervera R, Khamashta MA, Font J, Sebastiani GD, Gil A, Lavilla P, et al. Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients. Medicine (Baltimore) 2003;82:299–308.
    • (2003) Medicine (Baltimore) , vol.82 , pp. 299-308
    • Cervera, R.1    Khamashta, M.A.2    Font, J.3    Sebastiani, G.D.4    Gil, A.5    Lavilla, P.6
  • 10
    • 84873046059 scopus 로고    scopus 로고
    • Mechanisms of premature atherosclerosis in rheumatoid arthritis and lupus
    • Kahlenberg JM, Kaplan MJ. Mechanisms of premature atherosclerosis in rheumatoid arthritis and lupus. Annu Rev Med 2013;64:249–63.
    • (2013) Annu Rev Med , vol.64 , pp. 249-263
    • Kahlenberg, J.M.1    Kaplan, M.J.2
  • 12
    • 84903523652 scopus 로고    scopus 로고
    • Discovery and development of Janus kinase (JAK) inhibitors for inflammatory diseases
    • Clark JD, Flanagan ME, Telliez JB. Discovery and development of Janus kinase (JAK) inhibitors for inflammatory diseases. J Med Chem 2014;57:5023–38.
    • (2014) J Med Chem , vol.57 , pp. 5023-5038
    • Clark, J.D.1    Flanagan, M.E.2    Telliez, J.B.3
  • 14
    • 84885166129 scopus 로고    scopus 로고
    • The arrival of JAK inhibitors: advancing the treatment of immune and hematologic disorders
    • Furumoto Y, Gadina M. The arrival of JAK inhibitors: advancing the treatment of immune and hematologic disorders. BioDrugs 2013;27:431–8.
    • (2013) BioDrugs , vol.27 , pp. 431-438
    • Furumoto, Y.1    Gadina, M.2
  • 15
    • 79955027327 scopus 로고    scopus 로고
    • Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550)
    • Ghoreschi K, Jesson MI, Li X, Lee JL, Ghosh S, Alsup JW, et al. Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550). J Immunol 2011;186:4234–43.
    • (2011) J Immunol , vol.186 , pp. 4234-4243
    • Ghoreschi, K.1    Jesson, M.I.2    Li, X.3    Lee, J.L.4    Ghosh, S.5    Alsup, J.W.6
  • 16
    • 84908315856 scopus 로고    scopus 로고
    • Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition
    • Xing L, Dai Z, Jabbari A, Cerise JE, Higgins CA, Gong W, et al. Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition. Nat Med 2014;20:1043–9.
    • (2014) Nat Med , vol.20 , pp. 1043-1049
    • Xing, L.1    Dai, Z.2    Jabbari, A.3    Cerise, J.E.4    Higgins, C.A.5    Gong, W.6
  • 17
    • 84897068116 scopus 로고    scopus 로고
    • Reversal of CD8 T-cell-mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib
    • Okiyama N, Furumoto Y, Villarroel VA, Linton JT, Tsai WL, Gutermuth J, et al. Reversal of CD8 T-cell-mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib. J Invest Dermatol 2014;134:992–1000.
    • (2014) J Invest Dermatol , vol.134 , pp. 992-1000
    • Okiyama, N.1    Furumoto, Y.2    Villarroel, V.A.3    Linton, J.T.4    Tsai, W.L.5    Gutermuth, J.6
  • 18
    • 77958144092 scopus 로고    scopus 로고
    • The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction
    • Thacker SG, Berthier CC, Mattinzoli D, Rastaldi MP, Kretzler M, Kaplan MJ. The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction. J Immunol 2010;185:4457–69.
    • (2010) J Immunol , vol.185 , pp. 4457-4469
    • Thacker, S.G.1    Berthier, C.C.2    Mattinzoli, D.3    Rastaldi, M.P.4    Kretzler, M.5    Kaplan, M.J.6
  • 19
    • 84901451704 scopus 로고    scopus 로고
    • STAT1 as a central mediator of IFNγ and TLR4 signal integration in vascular dysfunction
    • Sikorski K, Chmielewski S, Olejnik A, Wesoly JZ, Heemann U, Baumann M, et al. STAT1 as a central mediator of IFNγ and TLR4 signal integration in vascular dysfunction. JAKSTAT 2012;1:241–9.
    • (2012) JAKSTAT , vol.1 , pp. 241-249
    • Sikorski, K.1    Chmielewski, S.2    Olejnik, A.3    Wesoly, J.Z.4    Heemann, U.5    Baumann, M.6
  • 21
    • 0025875259 scopus 로고
    • Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen PL, Eisenberg RA. Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu Rev Immunol 1991;9:243–69.
    • (1991) Annu Rev Immunol , vol.9 , pp. 243-269
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 22
    • 0018072901 scopus 로고
    • Spontaneous murine lupus-like syndromes: clinical and immunopathological manifestations in several strains
    • Andrews BS, Eisenberg RA, Theofilopoulos AN, Izui S, Wilson CB, McConahey PJ, et al. Spontaneous murine lupus-like syndromes: clinical and immunopathological manifestations in several strains. J Exp Med 1978;148:1198–215.
    • (1978) J Exp Med , vol.148 , pp. 1198-1215
    • Andrews, B.S.1    Eisenberg, R.A.2    Theofilopoulos, A.N.3    Izui, S.4    Wilson, C.B.5    McConahey, P.J.6
  • 23
    • 84949904309 scopus 로고    scopus 로고
    • Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice
    • Knight JS, Subramanian V, O'Dell AA, Yalavarthi S, Zhao W, Smith CK, et al. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Ann Rheum Dis 2015;74:2199–206.
    • (2015) Ann Rheum Dis , vol.74 , pp. 199-206
    • Knight, J.S.1    Subramanian, V.2    O'Dell, A.A.3    Yalavarthi, S.4    Zhao, W.5    Smith, C.K.6
  • 24
    • 84946575352 scopus 로고    scopus 로고
    • Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice
    • Stock AD, Wen J, Doerner J, Herlitz LC, Gulinello M, Putterman C. Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice. J Neuroinflammation 2015;12:205.
    • (2015) J Neuroinflammation , vol.12 , pp. 205
    • Stock, A.D.1    Wen, J.2    Doerner, J.3    Herlitz, L.C.4    Gulinello, M.5    Putterman, C.6
  • 25
    • 84964570069 scopus 로고    scopus 로고
    • Development of Th17-associated interstitial kidney inflammation in lupus-prone mice lacking the gene encoding STAT-1
    • Yiu G, Rasmussen TK, Ajami B, Haddon DJ, Chu AD, Tangsombatvisit S, et al. Development of Th17-associated interstitial kidney inflammation in lupus-prone mice lacking the gene encoding STAT-1. Arthritis Rheumatol 2016;68:1233–44.
    • (2016) Arthritis Rheumatol , vol.68 , pp. 1233-1244
    • Yiu, G.1    Rasmussen, T.K.2    Ajami, B.3    Haddon, D.J.4    Chu, A.D.5    Tangsombatvisit, S.6
  • 27
    • 84938512496 scopus 로고    scopus 로고
    • Interleukin 10 hampers endothelial cell differentiation and enhances the effects of interferon α on lupus endothelial cell progenitors
    • Cates AM, Holden VI, Myers EM, Smith CK, Kaplan MJ, Kahlenberg JM. Interleukin 10 hampers endothelial cell differentiation and enhances the effects of interferon α on lupus endothelial cell progenitors. Rheumatology (Oxford) 2015;54:1114–23.
    • (2015) Rheumatology (Oxford) , vol.54 , pp. 1114-1123
    • Cates, A.M.1    Holden, V.I.2    Myers, E.M.3    Smith, C.K.4    Kaplan, M.J.5    Kahlenberg, J.M.6
  • 30
    • 70349238893 scopus 로고    scopus 로고
    • The role of IL-23/IL-17 axis in lupus nephritis
    • Zhang Z, Kyttaris VC, Tsokos GC. The role of IL-23/IL-17 axis in lupus nephritis. J Immunol 2009;183:3160–9.
    • (2009) J Immunol , vol.183 , pp. 3160-3169
    • Zhang, Z.1    Kyttaris, V.C.2    Tsokos, G.C.3
  • 31
    • 84946486019 scopus 로고    scopus 로고
    • Janus kinase inhibitor tofacitinib shows potent efficacy in a mouse model of Autoimmune Lymphoproliferative Syndrome (ALPS)
    • Yokoyama S, Perera PY, Terawaki S, Watanabe N, Kaminuma O, Waldmann TA, et al. Janus kinase inhibitor tofacitinib shows potent efficacy in a mouse model of Autoimmune Lymphoproliferative Syndrome (ALPS). J Clin Immunol 2015;35:661–7.
    • (2015) J Clin Immunol , vol.35 , pp. 661-667
    • Yokoyama, S.1    Perera, P.Y.2    Terawaki, S.3    Watanabe, N.4    Kaminuma, O.5    Waldmann, T.A.6
  • 32
    • 84857788719 scopus 로고    scopus 로고
    • A novel pathogenetic concept-antiviral immunity in lupus nephritis
    • Migliorini A, Anders HJ. A novel pathogenetic concept-antiviral immunity in lupus nephritis. Nat Rev Nephrol 2012;8:183–9.
    • (2012) Nat Rev Nephrol , vol.8 , pp. 183-189
    • Migliorini, A.1    Anders, H.J.2
  • 33
    • 35548948085 scopus 로고    scopus 로고
    • Interferon-α promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis
    • Denny MF, Thacker S, Mehta H, Somers EC, Dodick T, Barrat FJ, et al. Interferon-α promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis. Blood 2007;110:2907–15.
    • (2007) Blood , vol.110 , pp. 2907-2915
    • Denny, M.F.1    Thacker, S.2    Mehta, H.3    Somers, E.C.4    Dodick, T.5    Barrat, F.J.6
  • 34
    • 84938068138 scopus 로고    scopus 로고
    • Endothelial progenitor cell phenotype and function are impaired in childhood-onset systemic lupus erythematosus
    • Mohan S, Barsalou J, Bradley TJ, Slorach C, Reynolds JA, Hasni S, et al. Endothelial progenitor cell phenotype and function are impaired in childhood-onset systemic lupus erythematosus. Arthritis Rheumatol 2015;67:2257–62.
    • (2015) Arthritis Rheumatol , vol.67 , pp. 2257-2262
    • Mohan, S.1    Barsalou, J.2    Bradley, T.J.3    Slorach, C.4    Reynolds, J.A.5    Hasni, S.6
  • 35
    • 33750600290 scopus 로고    scopus 로고
    • Janus kinase 3 inhibition with CP-690,550 prevents allograft vasculopathy
    • Rousvoal G, Si MS, Lau M, Zhang S, Berry GJ, Flores MG, et al. Janus kinase 3 inhibition with CP-690,550 prevents allograft vasculopathy. Transpl Int 2006;19:1014–21.
    • (2006) Transpl Int , vol.19 , pp. 1014-1021
    • Rousvoal, G.1    Si, M.S.2    Lau, M.3    Zhang, S.4    Berry, G.J.5    Flores, M.G.6
  • 36
    • 84923614330 scopus 로고    scopus 로고
    • Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib
    • Charles-Schoeman C, Fleischmann R, Davignon J, Schwartz H, Turner SM, Beysen C, et al. Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib. Arthritis Rheumatol 2015;67:616–25.
    • (2015) Arthritis Rheumatol , vol.67 , pp. 616-625
    • Charles-Schoeman, C.1    Fleischmann, R.2    Davignon, J.3    Schwartz, H.4    Turner, S.M.5    Beysen, C.6
  • 37
    • 84894434405 scopus 로고    scopus 로고
    • Deficiency in type I interferon signaling prevents the early interferon-induced gene signature in pancreatic islets but not type 1 diabetes in NOD mice
    • Quah HS, Miranda-Hernandez S, Khoo A, Harding A, Fynch S, Elkerbout L, et al. Deficiency in type I interferon signaling prevents the early interferon-induced gene signature in pancreatic islets but not type 1 diabetes in NOD mice. Diabetes 2014;63:1032–40.
    • (2014) Diabetes , vol.63 , pp. 1032-1040
    • Quah, H.S.1    Miranda-Hernandez, S.2    Khoo, A.3    Harding, A.4    Fynch, S.5    Elkerbout, L.6
  • 39
    • 84944345319 scopus 로고    scopus 로고
    • Tofacitinib citrate for the treatment of vitiligo: a pathogenesis-directed therapy
    • Craiglow BG, King BA. Tofacitinib citrate for the treatment of vitiligo: a pathogenesis-directed therapy. JAMA Dermatol 2015;151:1110–2
    • (2015) JAMA Dermatol , vol.151 , pp. 1110-1112
    • Craiglow, B.G.1    King, B.A.2
  • 40
    • 12344299197 scopus 로고    scopus 로고
    • Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus
    • Blanco P, Pitard V, Viallard JF, Taupin JL, Pellegrin JL, Moreau JF. Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus. Arthritis Rheum 2005;52:201–11.
    • (2005) Arthritis Rheum , vol.52 , pp. 201-211
    • Blanco, P.1    Pitard, V.2    Viallard, J.F.3    Taupin, J.L.4    Pellegrin, J.L.5    Moreau, J.F.6
  • 41
    • 58849162766 scopus 로고    scopus 로고
    • Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys
    • Crispin JC, Oukka M, Bayliss G, Cohen RA, van Beek CA, Stillman IE, et al. Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys. J Immunol 2008;181:8761–6.
    • (2008) J Immunol , vol.181 , pp. 8761-8766
    • Crispin, J.C.1    Oukka, M.2    Bayliss, G.3    Cohen, R.A.4    van Beek, C.A.5    Stillman, I.E.6
  • 42
    • 45249097325 scopus 로고    scopus 로고
    • Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity
    • Wong CK, Lit LC, Tam LS, Li EK, Wong PT, Lam CW. Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity. Clin Immunol 2008;127:385–93.
    • (2008) Clin Immunol , vol.127 , pp. 385-393
    • Wong, C.K.1    Lit, L.C.2    Tam, L.S.3    Li, E.K.4    Wong, P.T.5    Lam, C.W.6
  • 43
    • 59249101944 scopus 로고    scopus 로고
    • IL-17 producing CD4+ T cells mediate accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice
    • Edgerton C, Crispin JC, Moratz CM, Bettelli E, Oukka M, Simovic M, et al. IL-17 producing CD4+ T cells mediate accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice. Clin Immunol 2009;130:313–21.
    • (2009) Clin Immunol , vol.130 , pp. 313-321
    • Edgerton, C.1    Crispin, J.C.2    Moratz, C.M.3    Bettelli, E.4    Oukka, M.5    Simovic, M.6
  • 44
    • 84897900832 scopus 로고    scopus 로고
    • IL-17 protects T cells from apoptosis and contributes to development of ALPS-like phenotypes
    • Boggio E, Clemente N, Mondino A, Cappellano G, Orilieri E, Gigliotti CL, et al. IL-17 protects T cells from apoptosis and contributes to development of ALPS-like phenotypes. Blood 2014;123:1178–86.
    • (2014) Blood , vol.123 , pp. 1178-1186
    • Boggio, E.1    Clemente, N.2    Mondino, A.3    Cappellano, G.4    Orilieri, E.5    Gigliotti, C.L.6
  • 45
    • 84859102455 scopus 로고    scopus 로고
    • Interleukin-17 deficiency reduced vascular inflammation and development of atherosclerosis in Western diet-induced apoE-deficient mice
    • Usui F, Kimura H, Ohshiro T, Tatsumi K, Kawashima A, Nishiyama A, et al. Interleukin-17 deficiency reduced vascular inflammation and development of atherosclerosis in Western diet-induced apoE-deficient mice. Biochem Biophys Res Commun 2012;420:72–7.
    • (2012) Biochem Biophys Res Commun , vol.420 , pp. 72-77
    • Usui, F.1    Kimura, H.2    Ohshiro, T.3    Tatsumi, K.4    Kawashima, A.5    Nishiyama, A.6
  • 46
    • 84881097754 scopus 로고    scopus 로고
    • Anti-interferon α treatment in SLE
    • Kirou KA, Gkrouzman E. Anti-interferon α treatment in SLE. Clin Immunol 2013;148:303–12.
    • (2013) Clin Immunol , vol.148 , pp. 303-312
    • Kirou, K.A.1    Gkrouzman, E.2
  • 47
    • 0033004426 scopus 로고    scopus 로고
    • Premature morbidity from cardiovascular and cerebrovascular diseases in women with systemic lupus erythematosus
    • Ward MM. Premature morbidity from cardiovascular and cerebrovascular diseases in women with systemic lupus erythematosus. Arthritis Rheum 1999;42:338–46.
    • (1999) Arthritis Rheum , vol.42 , pp. 338-346
    • Ward, M.M.1
  • 48
    • 84879677170 scopus 로고    scopus 로고
    • Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus
    • Knight JS, Zhao W, Luo W, Subramanian V, O'Dell AA, Yalavarthi S, et al. Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus. J Clin Invest 2013;123:2981–93.
    • (2013) J Clin Invest , vol.123 , pp. 2981-2993
    • Knight, J.S.1    Zhao, W.2    Luo, W.3    Subramanian, V.4    O'Dell, A.A.5    Yalavarthi, S.6
  • 49
    • 84863627803 scopus 로고    scopus 로고
    • Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis
    • Thacker SG, Zhao W, Smith CK, Luo W, Wang H, Vivekanandan-Giri A, et al. Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis. Arthritis Rheum 2012;64:2975–85.
    • (2012) Arthritis Rheum , vol.64 , pp. 2975-2985
    • Thacker, S.G.1    Zhao, W.2    Smith, C.K.3    Luo, W.4    Wang, H.5    Vivekanandan-Giri, A.6
  • 50
    • 77951935256 scopus 로고    scopus 로고
    • A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs
    • Denny MF, Yalavarthi S, Zhao W, Thacker SG, Anderson M, Sandy AR, et al. A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs. J Immunol 2010;184:3284–97.
    • (2010) J Immunol , vol.184 , pp. 3284-3297
    • Denny, M.F.1    Yalavarthi, S.2    Zhao, W.3    Thacker, S.G.4    Anderson, M.5    Sandy, A.R.6
  • 51
    • 84893779343 scopus 로고    scopus 로고
    • Impaired serum cholesterol efflux capacity in rheumatoid arthritis and systemic lupus erythematosus
    • Ronda N, Favari E, Borghi MO, Ingegnoli F, Gerosa M, Chighizola C, et al. Impaired serum cholesterol efflux capacity in rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 2014;73:609–15.
    • (2014) Ann Rheum Dis , vol.73 , pp. 609-615
    • Ronda, N.1    Favari, E.2    Borghi, M.O.3    Ingegnoli, F.4    Gerosa, M.5    Chighizola, C.6
  • 52
    • 0042887347 scopus 로고    scopus 로고
    • Influence of glucocorticoids and disease activity on total and high density lipoprotein cholesterol in patients with rheumatoid arthritis
    • Boers M, Nurmohamed MT, Doelman CJ, Lard LR, Verhoeven AC, Voskuyl AE, et al. Influence of glucocorticoids and disease activity on total and high density lipoprotein cholesterol in patients with rheumatoid arthritis. Ann Rheum Dis 2003;62:842–5.
    • (2003) Ann Rheum Dis , vol.62 , pp. 842-845
    • Boers, M.1    Nurmohamed, M.T.2    Doelman, C.J.3    Lard, L.R.4    Verhoeven, A.C.5    Voskuyl, A.E.6
  • 53
    • 84937123363 scopus 로고    scopus 로고
    • Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice
    • Thacker SG, Rousset X, Esmail S, Zarzour A, Jin X, Collins HL, et al. Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice. J Lipid Res 2015;56:1282–95.
    • (2015) J Lipid Res , vol.56 , pp. 1282-1295
    • Thacker, S.G.1    Rousset, X.2    Esmail, S.3    Zarzour, A.4    Jin, X.5    Collins, H.L.6
  • 54
    • 43849112498 scopus 로고    scopus 로고
    • The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation
    • Manshouri T, Quintas-Cardama A, Nussenzveig RH, Gaikwad A, Estrov Z, Prchal J, et al. The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation. Cancer Sci 2008;99:1265–73.
    • (2008) Cancer Sci , vol.99 , pp. 1265-1273
    • Manshouri, T.1    Quintas-Cardama, A.2    Nussenzveig, R.H.3    Gaikwad, A.4    Estrov, Z.5    Prchal, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.