-
1
-
-
84992092089
-
2016 ESC/eas guidelines for the management of dyslipidaemias: The task force for the management of dyslipidaemias of the european society of cardiology (ESC) and european atherosclerosis society (eas
-
Catapano AL, Graham I, De Backer G, Wiklund O, Chapman MJ, Drexel H, Hoes AW, Jennings CS, Landmesser U, Pedersen TR, Reiner Ž Riccardi G, Taskinen MR, Tokgozoglu L, Verschuren WM, Vlachopoulos C, Wood DA, Zamorano JL, 2016 ESC/EAS guidelines for the management of dyslipidaemias: The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS). Atherosclerosis 2016 253 281 344
-
(2016)
Atherosclerosis
, vol.253
, pp. 281-344
-
-
Catapano, A.L.1
Graham, I.2
De Backer, G.3
Wiklund, O.4
Chapman, M.J.5
Drexel, H.6
Hoes, A.W.7
Jennings, C.S.8
Landmesser, U.9
Pedersen, T.R.10
Reiner, Ž.11
Riccardi, G.12
Taskinen, M.R.13
Tokgozoglu, L.14
Verschuren, W.M.15
Vlachopoulos, C.16
Wood, D.A.17
Zamorano, J.L.18
-
2
-
-
0027501003
-
Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans
-
Dietschy JM, Turley SD, Spady DK, Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J Lipid Res 1993 34 1637 1659
-
(1993)
J Lipid Res
, vol.34
, pp. 1637-1659
-
-
Dietschy, J.M.1
Turley, S.D.2
Spady, D.K.3
-
3
-
-
33747145594
-
Thematic review series: Patient-oriented research Design and analysis of lipoprotein tracer kinetics studies in humans
-
Barrett PH, Chan DC, Watts GF, Thematic review series: patient-oriented research. Design and analysis of lipoprotein tracer kinetics studies in humans. J Lipid Res 2006 47 1607 1619. doi: 10.1194/jlr.R600017-JLR200
-
(2006)
J Lipid Res
, vol.47
, pp. 1607-1619
-
-
Barrett, P.H.1
Chan, D.C.2
Watts, G.F.3
-
4
-
-
84901318325
-
The metabolic and pharmacologic bases for treating atherogenic dyslipidaemia
-
Chan DC, Barrett PH, Watts GF, The metabolic and pharmacologic bases for treating atherogenic dyslipidaemia. Best Pract Res Clin Endocrinol Metab 2014 28 369 385. doi: 10.1016/j.beem.2013.10.001
-
(2014)
Best Pract Res Clin Endocrinol Metab
, vol.28
, pp. 369-385
-
-
Chan, D.C.1
Barrett, P.H.2
Watts, G.F.3
-
5
-
-
84897889156
-
PCSK9: A key modulator of cardiovascular health
-
Seidah NG, Awan Z, Chrétien M, Mbikay M, PCSK9: a key modulator of cardiovascular health. Circ Res 2014 114 1022 1036. doi: 10.1161/CIRCRESAHA.114.301621
-
(2014)
Circ Res
, vol.114
, pp. 1022-1036
-
-
Seidah, N.G.1
Awan, Z.2
Chrétien, M.3
Mbikay, M.4
-
6
-
-
84931033888
-
Are PCSK9 inhibitors the next breakthrough in the cardiovascular field?
-
Giugliano RP, Sabatine MS, Are PCSK9 inhibitors the next breakthrough in the cardiovascular field? J Am Coll Cardiol 2015 65 2638 2651. doi: 10.1016/j.jacc.2015.05.001
-
(2015)
J Am Coll Cardiol
, vol.65
, pp. 2638-2651
-
-
Giugliano, R.P.1
Sabatine, M.S.2
-
7
-
-
84899112104
-
Reduction of low-density lipoprotein cholesterol by monoclonal antibody inhibition of PCSK9
-
Stein EA, Raal F, Reduction of low-density lipoprotein cholesterol by monoclonal antibody inhibition of PCSK9. Annu Rev Med 2014 65 417 431. doi: 10.1146/annurev-med-022613-090402
-
(2014)
Annu Rev Med
, vol.65
, pp. 417-431
-
-
Stein, E.A.1
Raal, F.2
-
8
-
-
84922576720
-
Statins: Definitive translational research
-
suppl 1
-
Grundy SM, Statins: definitive translational research. Mol Med 2014 20 suppl 1 S20 S23. doi: 10.2119/molmed.2014.00194
-
(2014)
Mol Med
, vol.20
, pp. S20-S23
-
-
Grundy, S.M.1
-
9
-
-
39449125338
-
Dose-dependent effect of rosuvastatin on apolipoprotein B-100 kinetics in the metabolic syndrome
-
Ooi EM, Barrett PH, Chan DC, Nestel PJ, Watts GF, Dose-dependent effect of rosuvastatin on apolipoprotein B-100 kinetics in the metabolic syndrome. Atherosclerosis 2008 197 139 146. doi: 10.1016/j.atherosclerosis.2007.03.004
-
(2008)
Atherosclerosis
, vol.197
, pp. 139-146
-
-
Ooi, E.M.1
Barrett, P.H.2
Chan, D.C.3
Nestel, P.J.4
Watts, G.F.5
-
10
-
-
0036092983
-
Mechanism of action of a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor on apolipoprotein B-100 kinetics in visceral obesity
-
Chan DC, Watts GF, Barrett PH, Mori TA, Beilin LJ, Redgrave TG, Mechanism of action of a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor on apolipoprotein B-100 kinetics in visceral obesity. J Clin Endocrinol Metab 2002 87 2283 2289. doi: 10.1210/jcem.87.5.8455
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 2283-2289
-
-
Chan, D.C.1
Watts, G.F.2
Barrett, P.H.3
Mori, T.A.4
Beilin, L.J.5
Redgrave, T.G.6
-
11
-
-
0037339775
-
Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome
-
Watts GF, Barrett PH, Ji J, Serone AP, Chan DC, Croft KD, Loehrer F, Johnson AG, Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome. Diabetes 2003 52 803 811
-
(2003)
Diabetes
, vol.52
, pp. 803-811
-
-
Watts, G.F.1
Barrett, P.H.2
Ji, J.3
Serone, A.P.4
Chan, D.C.5
Croft, K.D.6
Loehrer, F.7
Johnson, A.G.8
-
12
-
-
84903718184
-
Characterization of a quantitative method to measure free proprotein convertase subtilisin/kexin type 9 in human serum
-
Colbert A, Umble-Romero A, Prokop S, Xu R, Gibbs J, Pederson S, Characterization of a quantitative method to measure free proprotein convertase subtilisin/kexin type 9 in human serum. MAbs 2014 6 1103 1113. doi: 10.4161/mabs.28719
-
(2014)
MAbs
, vol.6
, pp. 1103-1113
-
-
Colbert, A.1
Umble-Romero, A.2
Prokop, S.3
Xu, R.4
Gibbs, J.5
Pederson, S.6
-
13
-
-
0023737126
-
Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans
-
Kempen HJ, Glatz JF, Gevers Leuven JA, van der Voort HA, Katan MB, Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. J Lipid Res 1988 29 1149 1155
-
(1988)
J Lipid Res
, vol.29
, pp. 1149-1155
-
-
Kempen, H.J.1
Glatz, J.F.2
Gevers Leuven, J.A.3
Van Der Voort, H.A.4
Katan, M.B.5
-
14
-
-
0023876839
-
HMG-CoA reductase inhibitors for treatment of hypercholesterolemia
-
Grundy SM, HMG-CoA reductase inhibitors for treatment of hypercholesterolemia. N Engl J Med 1988 319 24 33. doi: 10.1056/NEJM198807073190105
-
(1988)
N Engl J Med
, vol.319
, pp. 24-33
-
-
Grundy, S.M.1
-
15
-
-
0036500834
-
Reverse engineering of biological complexity
-
Csete ME, Doyle JC, Reverse engineering of biological complexity. Science 2002 295 1664 1669. doi: 10.1126/science.1069981
-
(2002)
Science
, vol.295
, pp. 1664-1669
-
-
Csete, M.E.1
Doyle, J.C.2
-
16
-
-
0029888305
-
Differences in receptor binding of LDL subfractions
-
Campos H, Arnold KS, Balestra ME, Innerarity TL, Krauss RM, Differences in receptor binding of LDL subfractions. Arterioscler Thromb Vasc Biol 1996 16 794 801
-
(1996)
Arterioscler Thromb Vasc Biol
, vol.16
, pp. 794-801
-
-
Campos, H.1
Arnold, K.S.2
Balestra, M.E.3
Innerarity, T.L.4
Krauss, R.M.5
-
17
-
-
78651061207
-
Suppression of Idol expression is an additional mechanism underlying statin-induced up-regulation of hepatic LDL receptor expression
-
Dong B, Wu M, Cao A, Li H, Liu J, Suppression of Idol expression is an additional mechanism underlying statin-induced up-regulation of hepatic LDL receptor expression. Int J Mol Med 2011 27 103 110. doi: 10.3892/ijmm.2010.559
-
(2011)
Int J Mol Med
, vol.27
, pp. 103-110
-
-
Dong, B.1
Wu, M.2
Cao, A.3
Li, H.4
Liu, J.5
-
18
-
-
84901365380
-
Hepatic overexpression of idol increases circulating protein convertase subtilisin/kexin type 9 in mice and hamsters via dual mechanisms: Sterol regulatory element-binding protein 2 and low-density lipoprotein receptor-dependent pathways
-
Sasaki M, Terao Y, Ayaori M, Uto-Kondo H, Iizuka M, Yogo M, Hagisawa K, Takiguchi S, Yakushiji E, Nakaya K, Ogura M, Komatsu T, Ikewaki K, Hepatic overexpression of idol increases circulating protein convertase subtilisin/kexin type 9 in mice and hamsters via dual mechanisms: sterol regulatory element-binding protein 2 and low-density lipoprotein receptor-dependent pathways. Arterioscler Thromb Vasc Biol 2014 34 1171 1178. doi: 10.1161/ATVBAHA.113.302670
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, pp. 1171-1178
-
-
Sasaki, M.1
Terao, Y.2
Ayaori, M.3
Uto-Kondo, H.4
Iizuka, M.5
Yogo, M.6
Hagisawa, K.7
Takiguchi, S.8
Yakushiji, E.9
Nakaya, K.10
Ogura, M.11
Komatsu, T.12
Ikewaki, K.13
-
19
-
-
0030870265
-
Inhibition of cholesterogenesis decreases hepatic secretion of apoB-100 in normolipidemic subjects
-
pt 1
-
Watts GF, Naoumova RP, Kelly JM, Riches FM, Croft KD, Thompson GR, Inhibition of cholesterogenesis decreases hepatic secretion of apoB-100 in normolipidemic subjects. Am J Physiol 1997 273 3 pt 1 E462 E470
-
(1997)
Am J Physiol
, vol.273
, Issue.3
, pp. E462-E470
-
-
Watts, G.F.1
Naoumova, R.P.2
Kelly, J.M.3
Riches, F.M.4
Croft, K.D.5
Thompson, G.R.6
-
20
-
-
45549096592
-
Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB
-
Blasiole DA, Oler AT, Attie AD, Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. J Biol Chem 2008 283 11374 11381. doi: 10.1074/jbc.M710457200
-
(2008)
J Biol Chem
, vol.283
, pp. 11374-11381
-
-
Blasiole, D.A.1
Oler, A.T.2
Attie, A.D.3
-
21
-
-
3943090528
-
Apolipoprotein B100 metabolism in autosomal-dominant hypercholesterolemia related to mutations in PCSK9
-
Ouguerram K, Chetiveaux M, Zair Y, Costet P, Abifadel M, Varret M, Boileau C, Magot T, Krempf M, Apolipoprotein B100 metabolism in autosomal-dominant hypercholesterolemia related to mutations in PCSK9. Arterioscler Thromb Vasc Biol 2004 24 1448 1453. doi: 10.1161/01.ATV.0000133684.77013.88
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1448-1453
-
-
Ouguerram, K.1
Chetiveaux, M.2
Zair, Y.3
Costet, P.4
Abifadel, M.5
Varret, M.6
Boileau, C.7
Magot, T.8
Krempf, M.9
-
22
-
-
73849114174
-
PCSK9 dominant negative mutant results in increased LDL catabolic rate and familial hypobetalipoproteinemia
-
Cariou B, Ouguerram K, Zaïr Y, Guerois R, Langhi C, Kourimate S, Benoit I, Le May C, Gayet C, Belabbas K, Dufernez F, Chétiveaux M, Tarugi P, Krempf M, Benlian P, Costet P, PCSK9 dominant negative mutant results in increased LDL catabolic rate and familial hypobetalipoproteinemia. Arterioscler Thromb Vasc Biol 2009 29 2191 2197. doi: 10.1161/ATVBAHA.109.194191
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 2191-2197
-
-
Cariou, B.1
Ouguerram, K.2
Zaïr, Y.3
Guerois, R.4
Langhi, C.5
Kourimate, S.6
Benoit, I.7
Le May, C.8
Gayet, C.9
Belabbas, K.10
Dufernez, F.11
Chétiveaux, M.12
Tarugi, P.13
Krempf, M.14
Benlian, P.15
Costet, P.16
-
23
-
-
0018743864
-
Metabolic studies in familial hypercholesterolemia. Evidence for a gene-dosage effect in vivo
-
Bilheimer DW, Stone NJ, Grundy SM, Metabolic studies in familial hypercholesterolemia. Evidence for a gene-dosage effect in vivo. J Clin Invest 1979 64 524 533. doi: 10.1172/JCI109490
-
(1979)
J Clin Invest
, vol.64
, pp. 524-533
-
-
Bilheimer, D.W.1
Stone, N.J.2
Grundy, S.M.3
-
24
-
-
0023679756
-
Simvastatin, a competitive inhibitor of HMG-CoA reductase, lowers cholesterol saturation index of gallbladder bile
-
Duane WC, Hunninghake DB, Freeman ML, Pooler PA, Schlasner LA, Gebhard RL, Simvastatin, a competitive inhibitor of HMG-CoA reductase, lowers cholesterol saturation index of gallbladder bile. Hepatology 1988 8 1147 1150
-
(1988)
Hepatology
, vol.8
, pp. 1147-1150
-
-
Duane, W.C.1
Hunninghake, D.B.2
Freeman, M.L.3
Pooler, P.A.4
Schlasner, L.A.5
Gebhard, R.L.6
-
25
-
-
0038342948
-
Effect of a statin on hepatic apolipoprotein B-100 secretion and plasma campesterol levels in the metabolic syndrome
-
Watts GF, Chan DC, Barrett PH, O'Neill FH, Thompson GR, Effect of a statin on hepatic apolipoprotein B-100 secretion and plasma campesterol levels in the metabolic syndrome. Int J Obes Relat Metab Disord 2003 27 862 865. doi: 10.1038/sj.ijo.0802287
-
(2003)
Int J Obes Relat Metab Disord
, vol.27
, pp. 862-865
-
-
Watts, G.F.1
Chan, D.C.2
Barrett, P.H.3
O'Neill, F.H.4
Thompson, G.R.5
-
26
-
-
0029924138
-
Role of cholesterol in regulating apolipoprotein B secretion by the liver
-
Thompson GR, Naoumova RP, Watts GF, Role of cholesterol in regulating apolipoprotein B secretion by the liver. J Lipid Res 1996 37 439 447
-
(1996)
J Lipid Res
, vol.37
, pp. 439-447
-
-
Thompson, G.R.1
Naoumova, R.P.2
Watts, G.F.3
-
27
-
-
0028173897
-
Structures and functions of multiligand lipoprotein receptors: Macrophage scavenger receptors and LDL receptor-related protein (LRP
-
Krieger M, Herz J, Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP). Annu Rev Biochem 1994 63 601 637. doi: 10.1146/annurev.bi.63.070194.003125
-
(1994)
Annu Rev Biochem
, vol.63
, pp. 601-637
-
-
Krieger, M.1
Herz, J.2
-
28
-
-
0032895028
-
Remnant lipoprotein metabolism: Key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E
-
Mahley RW, Ji ZS, Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E. J Lipid Res 1999 40 1 16
-
(1999)
J Lipid Res
, vol.40
, pp. 1-16
-
-
Mahley, R.W.1
Ji, Z.S.2
-
29
-
-
42549109081
-
Apolipoprotein C-III: Understanding an emerging cardiovascular risk factor
-
Ooi EM, Barrett PH, Chan DC, Watts GF, Apolipoprotein C-III: understanding an emerging cardiovascular risk factor. Clin Sci (Lond) 2008 114 611 624. doi: 10.1042/CS20070308
-
(2008)
Clin Sci (Lond)
, vol.114
, pp. 611-624
-
-
Ooi, E.M.1
Barrett, P.H.2
Chan, D.C.3
Watts, G.F.4
-
30
-
-
53449092689
-
Atorvastatin and fenofibrate have comparable effects on VLDL-Apolipoprotein C-III kinetics in men with the metabolic syndrome
-
Chan DC, Watts GF, Ooi EM, Ji J, Johnson AG, Barrett PH, Atorvastatin and fenofibrate have comparable effects on VLDL-Apolipoprotein C-III kinetics in men with the metabolic syndrome. Arterioscler Thromb Vasc Biol 2008 28 1831 1837. doi: 10.1161/ATVBAHA.108.170530
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1831-1837
-
-
Chan, D.C.1
Watts, G.F.2
Ooi, E.M.3
Ji, J.4
Johnson, A.G.5
Barrett, P.H.6
-
31
-
-
38349117118
-
The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2
-
Poirier S, Mayer G, Benjannet S, Bergeron E, Marcinkiewicz J, Nassoury N, Mayer H, Nimpf J, Prat A, Seidah NG, The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2. J Biol Chem 2008 283 2363 2372. doi: 10.1074/jbc.M708098200
-
(2008)
J Biol Chem
, vol.283
, pp. 2363-2372
-
-
Poirier, S.1
Mayer, G.2
Benjannet, S.3
Bergeron, E.4
Marcinkiewicz, J.5
Nassoury, N.6
Mayer, H.7
Nimpf, J.8
Prat, A.9
Seidah, N.G.10
-
33
-
-
84867366658
-
Effect of fenofibrate and atorvastatin on VLDL apoE metabolism in men with the metabolic syndrome
-
Ooi EM, Ng TW, Watts GF, Chan DC, Barrett PH, Effect of fenofibrate and atorvastatin on VLDL apoE metabolism in men with the metabolic syndrome. J Lipid Res 2012 53 2443 2449. doi: 10.1194/jlr.P029223
-
(2012)
J Lipid Res
, vol.53
, pp. 2443-2449
-
-
Ooi, E.M.1
Ng, T.W.2
Watts, G.F.3
Chan, D.C.4
Barrett, P.H.5
-
34
-
-
84922670093
-
Efficacy and safety of evolocumab (AMG 145), a fully human monoclonal antibody to PCSK9, in hyperlipidaemic patients on various background lipid therapies: Pooled analysis of 1359 patients in four phase 2 trials
-
PROFICIO Investigators
-
Stein EA, Giugliano RP, Koren MJ, Raal FJ, Roth EM, Weiss R, Sullivan D, Wasserman SM, Somaratne R, Kim JB, Yang J, Liu T, Albizem M, Scott R, Sabatine MS, PROFICIO Investigators Efficacy and safety of evolocumab (AMG 145), a fully human monoclonal antibody to PCSK9, in hyperlipidaemic patients on various background lipid therapies: pooled analysis of 1359 patients in four phase 2 trials. Eur Heart J 2014 35 2249 2259. doi: 10.1093/eurheartj/ehu085
-
(2014)
Eur Heart J
, vol.35
, pp. 2249-2259
-
-
Stein, E.A.1
Giugliano, R.P.2
Koren, M.J.3
Raal, F.J.4
Roth, E.M.5
Weiss, R.6
Sullivan, D.7
Wasserman, S.M.8
Somaratne, R.9
Kim, J.B.10
Yang, J.11
Liu, T.12
Albizem, M.13
Scott, R.14
Sabatine, M.S.15
-
35
-
-
84905101303
-
Proprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and-independent mechanisms
-
Rashid S, Tavori H, Brown PE, Linton MF, He J, Giunzioni I, Fazio S, Proprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and-independent mechanisms. Circulation 2014 130 431 441. doi: 10.1161/CIRCULATIONAHA.113.006720
-
(2014)
Circulation
, vol.130
, pp. 431-441
-
-
Rashid, S.1
Tavori, H.2
Brown, P.E.3
Linton, M.F.4
He, J.5
Giunzioni, I.6
Fazio, S.7
-
36
-
-
84885644881
-
The extended abnormalities in lipoprotein metabolism in familial hypercholesterolemia: Developing a new framework for future therapies
-
Ooi EM, Barrett PH, Watts GF, The extended abnormalities in lipoprotein metabolism in familial hypercholesterolemia: developing a new framework for future therapies. Int J Cardiol 2013 168 1811 1818. doi: 10.1016/j.ijcard.2013.06.069
-
(2013)
Int J Cardiol
, vol.168
, pp. 1811-1818
-
-
Ooi, E.M.1
Barrett, P.H.2
Watts, G.F.3
-
37
-
-
84959163895
-
PCSK9 and triglyceride-rich lipoprotein metabolism
-
Druce I, Abujrad H, Ooi T, PCSK9 and triglyceride-rich lipoprotein metabolism. J Biomed Res 2015 29 429 436
-
(2015)
J Biomed Res
, vol.29
, pp. 429-436
-
-
Druce, I.1
Abujrad, H.2
Ooi, T.3
|