Impact of obesity and epicardial fat on early left atrial dysfunction assessed by cardiac MRI strain analysis

Cardiovascular Diabetology

Volumn 15, Issue 1, 2016, Pages

  Evin, Morgane ^a,b,c   Broadhouse, Kathryn M ^a,b   Callaghan, Fraser M ^a,b   McGrath, Rachel T ^d,e   Glastras, Sarah ^d,e   Kozor, Rebecca ^a,b,d   Hocking, Samantha L ^d   Lamy, Jérôme ^c   Redheuil, Alban ^c   Kachenoura, Nadjia ^c   Fulcher, Greg R ^d,e   Figtree, Gemma A ^a,b,d   Grieve, Stuart M ^a,b,f  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c SORBONNE UNIVERSITÉ   (France)

^d ROYAL NORTH SHORE HOSPITAL   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

^f ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

Cardiac dysfunction; Diastolic dysfunction; Fat distribution; Magnetic resonance studies; Obesity and type 2

Indexed keywords

HEMOGLOBIN A1C;

ADULT; ARTICLE; BODY FAT DISTRIBUTION; BODY MASS; CARDIOVASCULAR MAGNETIC RESONANCE; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ECHOCARDIOGRAPHY; EPICARDIAL FAT; FEMALE; HEART FAILURE; HEART LEFT ATRIUM; HEART LEFT ATRIUM FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART LEFT VENTRICLE VOLUME; HEART SIZE; HEART STROKE VOLUME; HUMAN; MALE; MUSCLE STRAIN; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ADIPOSE TISSUE; ALGORITHM; CASE CONTROL STUDY; CINE MAGNETIC RESONANCE IMAGING; COMPLICATION; COMPUTER ASSISTED DIAGNOSIS; DIABETES MELLITUS, TYPE 2; DIAGNOSTIC IMAGING; DIASTOLE; EARLY DIAGNOSIS; HEART ATRIUM FUNCTION; HEART DISEASES; HEART LEFT VENTRICLE FUNCTION; MIDDLE AGED; PATHOPHYSIOLOGY; PERICARDIUM; PREDICTIVE VALUE; RISK FACTOR;

ADIPOSE TISSUE; ADIPOSITY; ADULT; ALGORITHMS; ATRIAL FUNCTION, LEFT; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; DIASTOLE; EARLY DIAGNOSIS; FEMALE; HEART DISEASES; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING, CINE; MALE; MIDDLE AGED; OBESITY; PERICARDIUM; PREDICTIVE VALUE OF TESTS; RISK FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 85006868266     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-016-0481-7     Document Type: Article

References (34)

1. Hogg K, Swedberg K, McMurray J. Heart failure with preserved left ventricular systolic function: epidemiology, clinical characteristics, and prognosis. J Am Coll Cardiol. 2004;43:317-27.
2. Gillebert TC, De Buyzere ML. HFpEF, diastolic suction, and exercise. JACC Cardiovasc Imaging. 2012;5:871-3.
3. Pirozzi F, Paglia A, Sasso L, Abete P, Carlomagno A, Tocchetti CG, Bonaduce D, Petretta M. Mitral peak early diastolic filling velocity to deceleration time ratio as a predictor of prognosis in patients with chronic heart failure and preserved or reduced ejection fraction. J Geriatr Cardiol: JGC. 2015;12:346-52.
4. Buffle E, Kramarz J, Elazar E, Aviram G, Ingbir M, Nesher N, Biner S, Keren G, Topilsky Y. Added value of pulmonary venous flow Doppler assessment in patients with preserved ejection fraction and its contribution to the diastolic grading paradigm. Eur Heart J Cardiovasc Imaging. 2015;16:1191-7.
5. Borlaug BA, Paulus WJ. Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment. Eur Heart J. 2011;32(6):670-9.
6. Nanayakkara S, Kaye DM. Management of heart failure with preserved ejection fraction: a review. Clin Ther. 2015;37(10):2186-98
7. Kurt M, Wang J, Torre-Amione G, Nagueh SF. Left atrial function in diastolic heart failure. Circ Cardiovasc Imaging. 2009;2:10-5.
8. Santos ABS, Kraigher-Krainer E, Gupta DK, Claggett B, Zile MR, Pieske B, Voors AA, Lefkowitz M, Bransford T, Shi V, et al. Impaired left atrial function in heart failure with preserved ejection fraction. Eur J Heart Fail. 2014;16:1096-103.
9. Mookadam F, Goel R, Alharthi MS, Jiamsripong P, Cha S. Epicardial fat and its association with cardiovascular risk: a cross-sectional observational study. Heart Views. 2010;11:103-8.
10. Kilicaslan B, Ozdogan O, Aydin M, Dursun H, Susam I, Ertas F. Increased epicardial fat thickness is associated with cardiac functional changes in healthy women. The Tohoku J Exp Med. 2012;228:119-24.
11. Fox CS, Gona P, Hoffmann U, Porter SA, Salton CJ, Massaro JM, Levy D, Larson MG, D'Agostino RB, O'Donnell CJ, et al. Pericardial fat, intrathoracic fat, and measures of left ventricular structure and function: the Framingham Heart Study. Circulation. 2009;119:1586-91.
12. Evin M, Redheuil A, Soulat G, Perdrix L, Ashrafpoor G, Giron A, Lamy J, Defrance C, Roux C, Hatem SN, et al. Left atrial aging: a cardiac magnetic resonance feature tracking study. Am J Phys Heart Circ Physiol. 2016;310(5):H542-9.
13. Inoue YY, Alissa A, Khurram IM, Fukumoto K, Habibi M, Venkatesh BA, Zimmerman SL, Nazarian S, Berger RD, Calkins H, et al. Quantitative tissue-tracking cardiac magnetic resonance (CMR) of left atrial deformation and the risk of stroke in patients with atrial fibrillation. Am Heart J. 2015;4:e001844.
14. Evin M, Cluzel P, Lamy J, Rosenbaum D, Kusmia S, Defrance C, Soulat G, Mousseaux E, Roux C, Clement K, et al. Assessment of left atrial function by MRI myocardial feature tracking. J Magn Res Imaging. 2015;42:379-89.
15. Liu C-Y, Redheuil A, Ouwerkerk R, Lima JAC, Bluemke DA. Myocardial fat quantification in humans: evaluation by two-point water-fat imaging and localized proton spectroscopy. Magn Res Med. 2010;63:892-901.
16. Heiberg E, Sjögren J, Ugander M, Carlsson M, Engblom H, Arheden H. Design and validation of segment-freely available software for cardiovascular image analysis. BMC Med Imaging. 2010;10:1.
17. Nagueh SF, Bierig SM, Budoff MJ, Desai M, Dilsizian V, Eidem B, Goldstein SA, Hung J, Maron MS, Ommen SR, et al. American Society of Echocardiography clinical recommendations for multimodality cardiovascular imaging of patients with hypertrophic cardiomyopathy: endorsed by the American society of nuclear cardiology, society for cardiovascular magnetic resonance, and society of cardiovascular computed tomography. J Am Soc Echocardiogr. 2011;24:473-98.
18. Kawata T, Daimon M, Miyazaki S, Ichikawa R, Maruyama M, Chiang S-J, Ito C, Sato F, Watada H, Daida H. Coronary microvascular function is independently associated with left ventricular filling pressure in patients with type 2 diabetes mellitus. Cardiovasc Diabetol. 2015;14:98.
19. Mochizuki Y, Tanaka H, Matsumoto K, Sano H, Toki H, Shimoura H, Ooka J, Sawa T, Motoji Y, Ryo K, et al. Clinical features of subclinical left ventricular systolic dysfunction in patients with diabetes mellitus. Cardiovasc Diabetol. 2015;14:37.
20. Gabrielli L, Enríquez A, Córdova S, Yáñez F, Godoy I, Corbalán R. Assessment of left atrial function in hypertrophic cardiomyopathy and athlete's heart: a left atrial myocardial deformation study. Echocardiography. 2012;29:943-9.
21. Lavie CJ, Amodeo C, Ventura HO, Messerli FH. LEft atrial abnormalities indicating diastolic ventricular dysfunction in cardiopathy of obesity. Chest. 1987;92:1042-6.
22. Tsang TSM, Barnes ME, Miyasaka Y, Cha SS, Bailey KR, Verzosa GC, Seward JB, Gersh BJ. Obesity as a risk factor for the progression of paroxysmal to permanent atrial fibrillation: a longitudinal cohort study of 21 years. Eur Heart J. 2008;29:2227-33.
23. Wierzbowska-Drabik K, Chrzanowski L, Kapusta A, Uznańska-Loch B, Płońska E, Krzemińska-Pakuła M, Kurpesa M, Rechciński T, Trzos E, Kasprzak JD. Severe obesity impairs systolic and diastolic heart function-the significance of pulsed tissue Doppler, strain, and strain rate parameters. Echocardiography. 2013;30:904-11.
24. Patil VC, Patil HV, Shah KB, Vasani JD, Shetty P. Diastolic dysfunction in asymptomatic type 2 diabetes mellitus with normal systolic function. J Cardiovasc Dis Res. 2011;2:213-22.
25. Enomoto M, Ishizu T, Seo Y, Yamamoto M, Suzuki H, Shimano H, Kawakami Y, Aonuma K. Subendocardial systolic dysfunction in asymptomatic normotensive diabetic patients. Circ J. 2015;79(8):1749-55.
26. Cassidy S, Hallsworth K, Thoma C, MacGowan GA, Hollingsworth KG, Day CP, Taylor R, Jakovljevic DG, Trenell MI. Cardiac structure and function are altered in type 2 diabetes and non-alcoholic fatty liver disease and associate with glycemic control. Cardiovasc Diabetol. 2015;14:23.
27. Kadappu KK, Boyd A, Eshoo S, Haluska B, Yeo AET, Marwick TH, Thomas L. Changes in left atrial volume in diabetes mellitus: more than diastolic dysfunction? Eur Heart J Cardiovasc Imaging. 2012;13:1016-23.
28. Wang Y, Hou D, Ma R, Ding G, Yin L, Zhang M. Early detection of left atrial energy loss and mechanics abnormalities in diabetic patients with normal left atrial size: a study combining vector flow mapping and tissue tracking echocardiography. Med Sci Monit. 2016;22:958-68.
29. Guan Z, Zhang D, Huang R, Zhang F, Wang Q, Guo S. Association of left atrial myocardial function with left ventricular diastolic dysfunction in subjects with preserved systolic function: a strain rate imaging study. Clin Cardiol. 2010;33:643-9.
30. Sosnovik DE, Wang R, Dai G, Reese TG, Wedeen VJ. Diffusion MR tractography of the heart. J Cardiovasc Magn Reson. 2009;11:47.
31. Ling L-H, McLellan AJA, Taylor AJ, Iles LM, Ellims AH, Kumar S, Teh A, Lee G, Wong MCG, Azzopardi S, et al. Magnetic resonance post-contrast T1 mapping in the human atrium: validation and impact on clinical outcome after catheter ablation for atrial fibrillation. Heart Rhythm. 2014;11:1551-9.
32. Hudsmith LE, Neubauer S. Magnetic resonance spectroscopy in myocardial disease. JACC Cardiovasc Imaging. 2009;2(1):87-96.
33. Chao T-F, Lai Y-H, Yun C-H, Yen C-H, Wang K-L, Lin Y-J, Chang S-L, Lo L-W, Hu Y-F, Hung C-L, et al. The association between atrium electromechanical interval and pericardial fat. PLoS One. 2014;9(5):e97472.
34. Homsi R, Meier-Schroers M, Gieseke J, Dabir D, Luetkens JA, Kuetting DL, Naehle CP, Marx C, Schild HH, Thomas DK, et al. 3D-Dixon MRI based volumetry of peri- and epicardial fat. Int J Cardiovasc Imaging. 2016;32(2):291-9.