Multilocus sequence typing analysis of carbapenem-resistant Acinetobacter baumannii in a Chinese Burns Institute

Frontiers in Microbiology

Volumn 7, Issue NOV, 2016, Pages

  Huang, Guangtao ^a   Yin, Supeng ^a   Gong, Yali ^a   Zhao, Xia ^a   Zou, Lingyun ^a   Jiang, Bei ^a   Dong, Zhiwei ^a   Chen, Yu ^a   Chen, Jing ^a   Jin, Shouguang ^b   Yuan, Zhiqiang ^a   Peng, Yizhi ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

A. baumannii; Clonal complex (CC); Multi locus sequence typing (MLST); Nosocomial infection; lactamases

Indexed keywords

AMIKACIN; CEFEPIME; CEFOPERAZONE PLUS SULBACTAM; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; MINOCYCLINE; NETILMICIN; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; POLYMYXIN B; RNA 16S; SULTAMICILLIN; TETRACYCLINE; TOBRAMYCIN;

ACINETOBACTER BAUMANNII; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BURN; MULTILOCUS SEQUENCE TYPING; NONHUMAN; OXA 23 GENE; OXA 51 GENE; POLYMERASE CHAIN REACTION; SUPPURATION;

EID: 85006792245     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2016.01717     Document Type: Article

References (28)

1. Bahador, A., Raoofian, R., Pourakbari, B., Taheri, M., Hashemizadeh, Z., and Hashemi, F. B. (2015). Genotypic and antimicrobial susceptibility of carbapenem-resistant Acinetobacter baumannii: analysis of is Aba elements and bla OXA-23-like genes including a new variant. Front. Microbiol. 6:1249. doi: 10.3389/fmicb.2015.01249.
2. Bartual, S. G., Seifert, H., Hippler, C., Luzon, M. A. D., Wisplinghoff, H., and Rodriguez-Valera, F. (2005). Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii. J. Clin. Microbiol. 43, 4382-4390. doi: 10.1128/jcm.43.9.4382-4390.2005.
3. Dijkshoorn, L., Nemec, A., and Seifert, H. (2007). An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat. Rev. Microbiol. 5, 939-951. doi: 10.1038/nrmicro1789.
4. El-Shazly, S., Dashti, A., Vali, L., Bolaris, M., and Ibrahim, A. S. (2015). Molecular epidemiology and characterization of multiple drug-resistant (MDR) clinical isolates of Acinetobacter baumannii. Int. J. Infect. Dis. 41, 42-49. doi: 10.1016/j.ijid.2015.10.016.
5. Farshadzadeh, Z., Hashemi, F. B., Rahimi, S., Pourakbari, B., Esmaeili, D., Haghighi, M. A., et al. (2015). Wide distribution of carbapenem resistant Acinetobacter baumannii in burns patients in Iran. Front. Microbiol. 6:1146. doi: 10.3389/fmicb.2015.01146.
6. Feil, E. J., Li, B. C., Aanensen, D. M., Hanage, W. P., and Spratt, B. G. (2004). eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data. J. Bacteriol. 186, 1518-1530. doi: 10.1128/JB.186.5.1518-1530.2004.
7. Fournier, P. E., Vallenet, D., Barbe, V., Audic, S., Ogata, H., Poirel, L., et al. (2006). Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS Genet. 2:e7. doi: 10.1371/journal.pgen.0020007.
8. Francisco, A. P., Bugalho, M., Ramirez, M., and Carrico, J. A. (2009). Global optimal eBURST analysis of multilocus typing data using a graphic matroid approach. BMC Bioinformatics 10:152. doi: 10.1186/1471-2105-10-152.
9. Guindon, S., Dufayard, J. F., Lefort, V., Anisimova, M., Hordijk, W., and Gascuel, O. (2010). New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst. Biol. 59, 307-321. doi: 10.1093/sysbio/syq010.
10. Hagihara, M., Housman, S. T., Nicolau, D. P., and Kuti, J. L. (2014). In vitro pharmacodynamics of polymyxin B and tigecycline alone and in combination against carbapenem-resistant Acinetobacter baumannii. Antimicrob. Agents Chemother. 58, 874-879. doi: 10.1128/AAC.01624-13.
11. Hammerum, A. M., Hansen, F., Skov, M. N., Stegger, M., Andersen, P. S., Holm, A., et al. (2015). Investigation of a possible outbreak of carbapenem-resistant Acinetobacter baumannii in Odense, Denmark using PFGE, MLST and whole-genome-based SNPs. J. Antimicrob. Chemother. 70, 1965-1968. doi: 10.1093/jac/dkv072.
12. Huang, G., Le, S., Peng, Y., Zhao, Y., Yin, S., Zhang, L., et al. (2013). Characterization and genome sequencing of phage Abp1, a new phiKMV-like virus infecting multidrug-resistant Acinetobacter baumannii. Curr. Microbiol. 66, 535-543. doi: 10.1007/s00284-013-0308-7.
13. Huang, G., Shen, X., Gong, Y., Dong, Z., Zhao, X., Shen, W., et al. (2014). Antibacterial properties of Acinetobacter baumannii phage Abp1 endolysin (PlyAB1). BMC Infect. Dis. 14:681. doi: 10.1186/s12879-014-0681-2.
14. Ji, S., Chen, Y., Ruan, Z., Fu, Y., Ji, J., Wang, H., et al. (2014). Prevalence of carbapenem-hydrolyzing class D beta-lactamase genes in Acinetobacter spp. isolates in China. Eur. J. Clin. Microbiol. Infect. Dis. 33, 989-997. doi: 10.1007/s10096-013-2037-z.
15. Jia, W., Li, C., Zhang, H., Li, G., Liu, X., and Wei, J. (2015). Prevalence of genes of OXA-23 carbapenemase and AdeABC efflux pump associated with multidrug resistance of Acinetobacter baumannii isolates in the ICU of a comprehensive hospital of Northwestern China. Int. J. Environ. Res. Public Health 12, 10079-10092. doi: 10.3390/ijerph120810079.
16. Mugnier, P. D., Poirel, L., Naas, T., and Nordmann, P. (2010). Worldwide dissemination of the blaOXA-23 carbapenemase gene of Acinetobacter baumannii. Emerg. Infect. Dis. 16, 35-40. doi: 10.3201/eid1601.090852.
17. Peleg, A. Y., Seifert, H., and Paterson, D. L. (2008). Acinetobacter baumannii: emergence of a successful pathogen. Clin. Microbiol. Rev. 21, 538-582. doi: 10.1128/CMR.00058-07.
18. Qu, J., Du, Y., Yu, R., and Lu, X. (2016). The first outbreak caused by Acinetobacter baumannii ST208 and ST195 in China. BioMed. Res. Int. 2016:9254907. doi: 10.1155/2016/9254907.
19. Quinones, D., Carvajal, I., Perez, Y., Hart, M., Perez, J., Garcia, S., et al. (2015). High prevalence of bla OXA-23 in Acinetobacter spp. and detection of bla NDM-1 in A. soli in Cuba: report from National Surveillance Program (2010-2012). New microbes New infect. 7, 52-56. doi: 10.1016/j.nmni.2015.06.002.
20. Rice, L. B. (2010). Progress and challenges in implementing the research on ESKAPE pathogens. Infect. Control Hosp. Epidemiol. 31(Suppl. 1), S7-S10. doi: 10.1086/655995.
21. Ruan, Z., Chen, Y., Jiang, Y., Zhou, H., Zhou, Z., Fu, Y., et al. (2013). Wide distribution of CC92 carbapenem-resistant and OXA-23-producing Acinetobacter baumannii in multiple provinces of China. Int. J. Antimicrob. Agents 42, 322-328. doi: 10.1016/j.ijantimicag.2013.06.019.
22. Turton, J. F., Woodford, N., Glover, J., Yarde, S., Kaufmann, M. E., and Pitt, T. L. (2006). Identification of Acinetobacter baumannii by detection of the blaOXA-51-like carbapenemase gene intrinsic to this species. J. Clin. Microbiol. 44, 2974-2976. doi: 10.1128/JCM.01021-06.
23. Woksepp, H., Ryberg, A., Billstrom, H., Hallgren, A., Nilsson, L. E., Marklund, B. I., et al. (2014). Evaluation of high-resolution melting curve analysis of ligation-mediated real-time PCR, a rapid method for epidemiological typing of ESKAPE (Enterococcus faecium. Staphylococcus aureus. Klebsiella pneumoniae. Acinetobacter baumannii. Pseudomonas aeruginosa, and Enterobacter Species) pathogens. J. Clin. Microbiol. 52, 4339-4342. doi: 10.1128/JCM.02537-14.
24. Wu, W., He, Y., Lu, J., Lu, Y., Wu, J., and Liu, Y. (2015). Transition of blaOXA-58-like to blaOXA-23-like in Acinetobacter baumannii clinical isolates in Southern China: an 8-Year Study. PLoS ONE 10:e0137174. doi: 10.1371/journal.pone.0137174.
25. Yali, G., Jing, C., Chunjiang, L., Cheng, Z., Xiaoqiang, L., and Yizhi, P. (2014). Comparison of pathogens and antibiotic resistance of burn patients in the burn ICU or in the common burn ward. Burns 40, 402-407. doi: 10.1016/j.burns.2013.07.010.
26. Zander, E., Higgins, P. G., Fernandez-Gonzalez, A., and Seifert, H. (2013). Detection of intrinsic blaOXA-51-like by multiplex PCR on its own is not reliable for the identification of Acinetobacter baumannii. Int. J. Med. Microbiol. 303, 88-89. doi: 10.1016/j.ijmm.2012.12.007.
27. Zhou, Y., Wu, X., Zhang, X., Hu, Y., Yang, X., Yang, Z., et al. (2015). Genetic characterization of ST195 and ST365 carbapenem-resistant Acinetobacter baumannii harboring blaOXA-23 in Guangzhou, China. Microb. Drug Resist. 21, 386-390. doi: 10.1089/mdr.2014.0183.
28. Zowawi, H. M., Sartor, A. L., Sidjabat, H. E., Balkhy, H. H., Walsh, T. R., Al Johani, S. M., et al. (2015). Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii isolates in the gulf cooperation council states: dominance of OXA-23-type producers. J. Clin. Microbiol. 53, 896-903. doi: 10.1128/JCM.02784-14.