Quantifying the risk of nosocomial infection within Ebola Holding Units: a retrospective cohort study of negative patients discharged from five Ebola Holding Units in Western Area, Sierra Leone

Tropical Medicine and International Health

Volumn 22, Issue 1, 2017, Pages 32-40

  Arkell, Paul ^a   Youkee, Daniel ^a   Brown, Colin S ^a,b   Kamara, Abdul ^c   Kamara, Thaim B ^d   Johnson, Oliver ^a   Lado, Marta ^a   George, Viginia ^e   Koroma, Fatmata ^f   King, Matilda B ^g   Parker, Benson E ^h   Baker, Peter ^a,i  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b HOSPITAL FOR TROPICAL DISEASES   (United Kingdom)

^c Republic of Sierra Leone Ministry of Health and Sanitation   (Sierra Leone)

^d Connaught Government Hospital ^*  (Sierra Leone)

^e Lumley Government Hospital   (Sierra Leone)

^f Newton Community Health Centre   (Sierra Leone)

^g Rokupa Government Hospital   (Sierra Leone)

^h Macauley Street Government Hospital   (Sierra Leone)

ⁱ IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Ebola Holding Unit; Ebola virus disease; hygiene; infection prevention and control; nosocomial transmission; Sierra Leone

Indexed keywords

COHORT ANALYSIS; DISEASE CONTROL; DISEASE TRANSMISSION; EBOLA VIRUS DISEASE; EPIDEMIC; HEALTH RISK; HOSPITAL SECTOR; INFECTIOUS DISEASE; RISK ASSESSMENT; RISK FACTOR; VIRUS;

ADULT; ARTICLE; COHORT ANALYSIS; EBOLA HEMORRHAGIC FEVER; FEMALE; HOSPITAL DISCHARGE; HOSPITAL INFECTION; HOSPITAL READMISSION; HUMAN; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; RETROSPECTIVE STUDY; SIERRA LEONE; VIRUS TRANSMISSION; CROSS INFECTION; EPIDEMIC; HEALTH CARE FACILITY; HEMORRHAGIC FEVER, EBOLA; RISK ASSESSMENT; STATISTICS AND NUMERICAL DATA; TRANSMISSION;

SIERRA LEONE;

EBOLA VIRUS;

ADULT; CROSS INFECTION; EPIDEMICS; FEMALE; HEALTH FACILITIES; HEMORRHAGIC FEVER, EBOLA; HUMANS; MALE; PATIENT READMISSION; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SIERRA LEONE;

EID: 85006511796     PISSN: 13602276     EISSN: 13653156     Source Type: Journal    
DOI: 10.1111/tmi.12802     Document Type: Article

References (20)

1. World Health Organization. World Health Organisation, Ebola Situation Report 6th January 2016. Geneva: WHO; 2015 [Online]. (Available from: http://apps.who.int/ebola/current-situation/ebola-situation-report-6-january-2016) [13 Jan 2016].
2. King's Sierra Leone Partnership. A Guide for the Establishment and Supervision of Ebola Holding Units. Freetown: KSLP; 2014 [Online]. (Available from: http://kslp.org.uk/wp-content/uploads/2015/05/KSLP-Ebola-Holding-Unit-Guide-FINAL.pdf) [13 Jan 2016].
3. Lado M, Baker P, Walker NF et al. Clinical features of patients isolated for suspected Ebola Virus Disease at Connaught Hospital, Freetown, Sierra Leone: a retrospective cohort study. Lancet Infect Dis 2015: 15: 1024–33.
4. Bolkan HA, Bash-Taqi DA, Samai M, Gerdin M, von Schreeb J. Ebola and indirect effects on health service function in Sierra Leone. PLoS Curr 2014;6:pii.
5. Shears P, O'Dempsey TJ. Ebola virus disease in Africa: epidemiology and nosocomial transmission. J Hosp Infect 2015: 90: 1–9.
6. Ftika L, Maltezou HC. Viral haemorrhagic fevers in healthcare settings. J Hosp Infect 2013: 83: 185–92.
7. MacNeil A, Rollin PE. Ebola and Marburg hemorrhagic fevers: neglected tropical diseases? PLoS Negl Trop Dis 2012: 6: e1546.
8. World Health Organization. Ebola haemorrhagic fever in Sudan, 1976. Report of a WHO/International Study Team. Bull WHO 1978;56:247e270.
9. Fisher-Hoch SP, Tomori O, Nasidi A et al. Review of cases of nosocomial Lassa fever in Nigeria: the high price of poor medical practice. BMJ 1995: 311: 857–9.
10. Levine AC, Shetty PP, Burbach R et al. Derivation and internal validation of the ebola prediction score for risk stratification of patients with suspected Ebola virus disease. Ann Emerg Med 2015: 66: 285–293.
11. Dunn AC, Walker TA, Redd J et al. Nosocomial transmission of Ebola virus disease on pediatric and maternity wards: Bombali and Tonkolili, Sierra Leone, 2014. Am J Infect Control 2016: 44: 269–72.
12. Vogt F, Fitzpatrick G, Patten G et al. Assessment of the MSF triage system, separating patients into different wards pending Ebola virus laboratory confirmation, Kailahun, Sierra Leone, July to September 2014. Euro Surveill 2015: 20 (50):pii=30097.
13. Youkee D, Brown CS, Lilburn P et al. Assessment of environmental contamination and environmental decontamination practices within an Ebola Holding Unit, Freetown, Sierra Leone. PLoS One 2015: 10: e0145167.
14. Fitzpatrick G, Vogt F, Moi Gbabai O et al. Describing readmissions to an Ebola case management centre (CMC), Sierra Leone, 2014. Euro Surveill 2014: 19: 20924.
15. Western Area Emergency Response Centre, Ministry of Health and Sanitation, 2014–15. Western Area Live Case Management Weekly Reports. Freetown: WAERC; 2014–2015.
16. Bah EI, Lamah MC, Fletcher T et al. Clinical presentation of patients with Ebola virus disease in Conakry, Guinea. N Engl J Med 2015: 372: 40–7.
17. WHO Ebola Response Team. Ebola virus disease among male and female persons in West Africa. N Engl J Med 2016: 374: 96–98.
18. Personal Communication. Felicity Fitzgerald. Save The Children, Sierra Leone. Aug 2016.
19. Van Bortel T, Basnayake A, Wurie F et al. Psychosocial effects of an Ebola outbreak at individual, community and international levels. Bull World Health Organ 2016: 94: 210–4.
20. Walker NF, Brown CS, Youkee D et al. Evaluation of a point-of-care blood test for identification of Ebola virus disease at Ebola holding units, Western Area, Sierra Leone, January to February 2015. Euro Surveill 2015: 20 (12):pii=21073.