Pyocyanin degradation by a tautomerizing demethylase inhibits Pseudomonas aeruginosa biofilms

Science

Volumn 355, Issue 6321, 2017, Pages

  Costa, Kyle C ^a   Glasser, Nathaniel R ^a   Conway, Stuart J ^b   Newman, Dianne K ^a,c  

^a California Institute of Technology   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL ENZYME; PYOCYANIN DEMETHYLASE; PYOCYANINE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; DNA; N DEMETHYLASE;

BACTERIUM; BIODEGRADATION; BIOFILM; ENZYME; ENZYME ACTIVITY; INHIBITION; METABOLITE; ORGANIC COMPOUND; PROTEIN; VIRULENCE;

ARTICLE; BIOFILM; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEGRADATION; DEMETHYLATION; DISSOCIATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; PSEUDOMONAS AERUGINOSA; TAUTOMERIZATION; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; METHYLATION; MYCOBACTERIUM FORTUITUM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; X RAY CRYSTALLOGRAPHY;

PSEUDOMONAS AERUGINOSA;

BACTERIAL PROTEINS; BIOFILMS; CRYSTALLOGRAPHY, X-RAY; DNA; METHYLATION; MYCOBACTERIUM FORTUITUM; OXIDATION-REDUCTION; OXIDOREDUCTASES, N-DEMETHYLATING; PSEUDOMONAS AERUGINOSA; PYOCYANINE;

EID: 85006493481     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aag3180     Document Type: Article

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