Failure of a heterologous recombinant Sca5/OmpB protein-based vaccine to elicit effective protective immunity against Rickettsia rickettsii infections in C3H/HeN mice

Pathogens and Disease

Volumn 73, Issue 9, 2015, Pages

  Riley, Sean P ^a,b,c   Cardwell, Marissa M ^a,b   Chan, Yvonne G Y ^a,b   Pruneau, Ludovic ^c   Piero, Fabio Del ^c   Martinez, Juan J ^a,b,c  

^a UNIVERSITY OF CHICAGO   (United States)

^b Howard T Ricketts Laboratory   (United States)

^c LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

C3H HeN mice; OmpB; Protective immunity; Rickettsia conorii; Rickettsia rickettsii; Spotted fever group

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL VACCINE; BACTERIUM ANTIBODY; OUTER MEMBRANE PROTEIN; RECOMBINANT VACCINE; SUBUNIT VACCINE;

ANIMAL; BLOOD; C3H MOUSE; CROSS PROTECTION; CROSS REACTION; DISEASE MODEL; GENETICS; IMMUNOLOGY; MALE; RICKETTSIA CONORII; RICKETTSIA RICKETTSII; ROCKY MOUNTAIN SPOTTED FEVER; SURVIVAL ANALYSIS;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; CROSS PROTECTION; CROSS REACTIONS; DISEASE MODELS, ANIMAL; MALE; MICE, INBRED C3H; RICKETTSIA CONORII; RICKETTSIA RICKETTSII; ROCKY MOUNTAIN SPOTTED FEVER; SURVIVAL ANALYSIS; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 85006205416     PISSN: None     EISSN: 2049632X     Source Type: Journal    
DOI: 10.1093/femspd/ftv101     Document Type: Article

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