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Volumn 5, Issue 6, 2015, Pages 2022-2034

Overexpression of forkhead Box C2 promotes tumor metastasis and indicates poor prognosis in colon cancer via regulating epithelial-mesenchymal transition

Author keywords

Colon cancer; EMT; FOXC2; Metastasis; Prognostic factor

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN KINASE B; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR FOXC2; TRANSCRIPTION FACTOR SNAIL;

EID: 85006184157     PISSN: None     EISSN: 21566976     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (67)

References (30)
  • 6
    • 84907196086 scopus 로고    scopus 로고
    • Circulating tumour cells and the epithelial mesenchymal transition in colorectal cancer
    • Lim SH, Becker TM, Chua W, Ng WL, de Souza P and Spring KJ. Circulating tumour cells and the epithelial mesenchymal transition in colorectal cancer. J Clin Pathol 2014; 67: 848-53.
    • (2014) J Clin Pathol , vol.67 , pp. 848-853
    • Lim, S.H.1    Becker, T.M.2    Chua, W.3    Ng, W.L.4    de Souza, P.5    Spring, K.J.6
  • 7
    • 84893146306 scopus 로고    scopus 로고
    • FOXM1c promotes pancreatic cancer epithelial- to-mesenchymal transition and metastasis via upregulation of expression of the urokinase plasminogen activator system
    • Huang C, Xie D, Cui J, Li Q, Gao Y and Xie K. FOXM1c promotes pancreatic cancer epithelial- to-mesenchymal transition and metastasis via upregulation of expression of the urokinase plasminogen activator system. Clin Cancer Res 2014; 20: 1477-1488.
    • (2014) Clin Cancer Res , vol.20 , pp. 1477-1488
    • Huang, C.1    Xie, D.2    Cui, J.3    Li, Q.4    Gao, Y.5    Xie, K.6
  • 8
    • 84883763813 scopus 로고    scopus 로고
    • FOXM1 promotes the epithelial to mesenchymal transition by stimulating the transcription of Slug in human breast cancer
    • Yang C, Chen H, Tan G, Gao W, Cheng L, Jiang X, Yu L and Tan Y. FOXM1 promotes the epithelial to mesenchymal transition by stimulating the transcription of Slug in human breast cancer. Cancer Lett 2013; 340: 104-112.
    • (2013) Cancer Lett , vol.340 , pp. 104-112
    • Yang, C.1    Chen, H.2    Tan, G.3    Gao, W.4    Cheng, L.5    Jiang, X.6    Yu, L.7    Tan, Y.8
  • 10
    • 84896850322 scopus 로고    scopus 로고
    • Forkhead box Q1 promotes hepatocellular carcinoma metastasis by transactivating ZEB2 and VersicanV1 expression
    • Xia L, Huang W, Tian D, Zhang L, Qi X, Chen Z, Shang X, Nie Y and Wu K. Forkhead box Q1 promotes hepatocellular carcinoma metastasis by transactivating ZEB2 and VersicanV1 expression. Hepatology 2014; 59: 958-973.
    • (2014) Hepatology , vol.59 , pp. 958-973
    • Xia, L.1    Huang, W.2    Tian, D.3    Zhang, L.4    Qi, X.5    Chen, Z.6    Shang, X.7    Nie, Y.8    Wu, K.9
  • 11
    • 79951849322 scopus 로고    scopus 로고
    • Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis
    • Zhang H, Meng F, Liu G, Zhang B, Zhu J, Wu F, Ethier SP, Miller F and Wu G. Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res 2011; 71: 1292-1301.
    • (2011) Cancer Res , vol.71 , pp. 1292-1301
    • Zhang, H.1    Meng, F.2    Liu, G.3    Zhang, B.4    Zhu, J.5    Wu, F.6    Ethier, S.P.7    Miller, F.8    Wu, G.9
  • 12
    • 84873316241 scopus 로고    scopus 로고
    • Overexpression of forkhead box C1 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma
    • Xia L, Huang W, Tian D, Zhu H, Qi X, Chen Z, Zhang Y, Hu H, Fan D, Nie Y and Wu K. Overexpression of forkhead box C1 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma. Hepatology 2013; 57: 610-624.
    • (2013) Hepatology , vol.57 , pp. 610-624
    • Xia, L.1    Huang, W.2    Tian, D.3    Zhu, H.4    Qi, X.5    Chen, Z.6    Zhang, Y.7    Hu, H.8    Fan, D.9    Nie, Y.10    Wu, K.11
  • 13
    • 77950293595 scopus 로고    scopus 로고
    • Loss of FOXA1/2 is essential for the epithelial-tomesenchymal transition in pancreatic cancer
    • Song Y, Washington MK and Crawford HC. Loss of FOXA1/2 is essential for the epithelial-tomesenchymal transition in pancreatic cancer. Cancer Res 2010; 70: 2115-2125.
    • (2010) Cancer Res , vol.70 , pp. 2115-2125
    • Song, Y.1    Washington, M.K.2    Crawford, H.C.3
  • 14
    • 84898739196 scopus 로고    scopus 로고
    • Downregulation of FOXO3a promotes tumor metastasis and is associated with metastasisfree survival of patients with clear cell renal cell carcinoma
    • Ni D, Ma X, Li HZ, Gao Y, Li XT, Zhang Y, Ai Q, Zhang P, Song EL, Huang QB, Fan Y and Zhang X. Downregulation of FOXO3a promotes tumor metastasis and is associated with metastasisfree survival of patients with clear cell renal cell carcinoma. Clin Cancer Res 2014; 20:1779-1790.
    • (2014) Clin Cancer Res , vol.20 , pp. 1779-1790
    • Ni, D.1    Ma, X.2    Li, H.Z.3    Gao, Y.4    Li, X.T.5    Zhang, Y.6    Ai, Q.7    Zhang, P.8    Song, E.L.9    Huang, Q.B.10    Fan, Y.11    Zhang, X.12
  • 15
    • 58649084829 scopus 로고    scopus 로고
    • Foxc2 transcription factor: a newly described regulator of angiogenesis
    • Kume T. Foxc2 transcription factor: a newly described regulator of angiogenesis. Trends Cardiovasc Med 2008; 18: 224-228.
    • (2008) Trends Cardiovasc Med , vol.18 , pp. 224-228
    • Kume, T.1
  • 22
    • 79957889846 scopus 로고    scopus 로고
    • KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis
    • Li D, Peng Z, Tang H, Wei P, Kong X, Yan D, Huang F, Li Q, Le X and Xie K. KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis. Clin Cancer Res 2011; 17: 3558-3568.
    • (2011) Clin Cancer Res , vol.17 , pp. 3558-3568
    • Li, D.1    Peng, Z.2    Tang, H.3    Wei, P.4    Kong, X.5    Yan, D.6    Huang, F.7    Li, Q.8    Le, X.9    Xie, K.10
  • 24
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
    • Zhou BP, Deng J, Xia W, Xu J, Li YM, Gunduz M and Hung MC. Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol 2004; 6: 931-940.
    • (2004) Nat Cell Biol , vol.6 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5    Gunduz, M.6    Hung, M.C.7
  • 25
    • 84902133689 scopus 로고    scopus 로고
    • Overexpressed FOXC2 in ovarian cancer enhances the epithelial-to-mesenchymal transition and invasion of ovarian cancer cells
    • Liu B, Han SM, Tang XY, Han L and Li CZ. Overexpressed FOXC2 in ovarian cancer enhances the epithelial-to-mesenchymal transition and invasion of ovarian cancer cells. Oncol Rep 2014; 31: 2545-2554.
    • (2014) Oncol Rep , vol.31 , pp. 2545-2554
    • Liu, B.1    Han, S.M.2    Tang, X.Y.3    Han, L.4    Li, C.Z.5
  • 27
    • 84905375763 scopus 로고    scopus 로고
    • FOXC2 often overexpressed in glioblastoma enhances proliferation and invasion in glioblastoma cells
    • Li W, Fu X, Liu R, Wu C, Bai J, Xu Y, Zhao Y and Xu Y. FOXC2 often overexpressed in glioblastoma enhances proliferation and invasion in glioblastoma cells. Oncol Res 2013; 21: 111-120.
    • (2013) Oncol Res , vol.21 , pp. 111-120
    • Li, W.1    Fu, X.2    Liu, R.3    Wu, C.4    Bai, J.5    Xu, Y.6    Zhao, Y.7    Xu, Y.8
  • 28
    • 12144266241 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelialmesenchymal transition
    • Bachelder RE, Yoon SO, Franci C, de Herreros AG and Mercurio AM. Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelialmesenchymal transition. J Cell Biol 2005; 168:29-33.
    • (2005) J Cell Biol , vol.168 , pp. 29-33
    • Bachelder, R.E.1    Yoon, S.O.2    Franci, C.3    de Herreros, A.G.4    Mercurio, A.M.5
  • 29
    • 23944526062 scopus 로고    scopus 로고
    • Activation of AKT kinases in cancer:implications for therapeutic targeting
    • Bellacosa A, Kumar CC, Di Cristofano A and Testa JR. Activation of AKT kinases in cancer:implications for therapeutic targeting. Adv Cancer Res 2005; 94: 29-86.
    • (2005) Adv Cancer Res , vol.94 , pp. 29-86
    • Bellacosa, A.1    Kumar, C.C.2    Di Cristofano, A.3    Testa, J.R.4
  • 30
    • 27844461512 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in development and cancer:role of phosphatidylinositol 3' kinase/AKT pathways
    • Larue L and Bellacosa A. Epithelial-mesenchymal transition in development and cancer:role of phosphatidylinositol 3' kinase/AKT pathways. Oncogene 2005; 24: 7443-7454.
    • (2005) Oncogene , vol.24 , pp. 7443-7454
    • Larue, L.1    Bellacosa, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.