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Volumn 60, Issue 3, 2017, Pages 531-540

Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia

Author keywords

Bariatric complication; GLP 1; Hyperinsulinaemic hypoglycaemia; Hypoglycaemia; Late dumping syndrome; Nesidioblastosis; Neuroglycopenia; NIPHS; Noninsulinoma pancreatogenous hypoglycaemia syndrome; Post bariatric hypoglycaemia; Roux en Y gastric bypass; RYGB

Indexed keywords

EXENDIN 9 39; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCOSE; HYPERGLYCEMIC AGENT; INCRETIN; INSULIN; PLACEBO; UNCLASSIFIED DRUG; EXENDIN 9; GASTRIC INHIBITORY POLYPEPTIDE; PEPTIDE FRAGMENT;

EID: 85006093261     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-016-4179-x     Document Type: Article
Times cited : (97)

References (48)
  • 1
    • 84896690513 scopus 로고    scopus 로고
    • Prevalence of childhood and adult obesity in the United States, 2011-2012
    • COI: 1:CAS:528:DC%2BC2cXjvVOhs74%3D, PID: 24570244
    • Ogden C, Carroll M, Kit B, Flegal K (2014) Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA 311:806–814
    • (2014) JAMA , vol.311 , pp. 806-814
    • Ogden, C.1    Carroll, M.2    Kit, B.3    Flegal, K.4
  • 2
    • 70349207410 scopus 로고    scopus 로고
    • Annual medical spending attributable to obesity: payer- and service-specific estimates
    • Finkelstein EA, Trogdon JG, Cohen JW, Dietz W (2009) Annual medical spending attributable to obesity: payer- and service-specific estimates. Health Aff 28:822–831
    • (2009) Health Aff , vol.28 , pp. 822-831
    • Finkelstein, E.A.1    Trogdon, J.G.2    Cohen, J.W.3    Dietz, W.4
  • 3
    • 10844295087 scopus 로고    scopus 로고
    • Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery
    • PID: 15616203
    • Sjostrom L, Lindroos AK, Peltonen M et al (2004) Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med 351:2683–2693
    • (2004) N Engl J Med , vol.351 , pp. 2683-2693
    • Sjostrom, L.1    Lindroos, A.K.2    Peltonen, M.3
  • 4
    • 34548075820 scopus 로고    scopus 로고
    • Long-term mortality after gastric bypass surgery
    • COI: 1:CAS:528:DC%2BD2sXpsF2iu7k%3D, PID: 17715409
    • Adams TD, Gress RE, Smith SC et al (2007) Long-term mortality after gastric bypass surgery. N Engl J Med 357:753–761
    • (2007) N Engl J Med , vol.357 , pp. 753-761
    • Adams, T.D.1    Gress, R.E.2    Smith, S.C.3
  • 5
    • 0029130754 scopus 로고
    • Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus
    • COI: 1:STN:280:DyaK2Mvgsl2ltA%3D%3D, PID: 7677463
    • Pories WJ, Swanson MS, MacDonald KG et al (1995) Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann Surg 222:339–350
    • (1995) Ann Surg , vol.222 , pp. 339-350
    • Pories, W.J.1    Swanson, M.S.2    MacDonald, K.G.3
  • 6
    • 10744222607 scopus 로고    scopus 로고
    • Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus
    • PID: 14530719
    • Schauer PR, Burguera B, Ikramuddin S et al (2003) Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus. Ann Surg 238:467–484
    • (2003) Ann Surg , vol.238 , pp. 467-484
    • Schauer, P.R.1    Burguera, B.2    Ikramuddin, S.3
  • 7
    • 84971268454 scopus 로고    scopus 로고
    • Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations
    • COI: 1:CAS:528:DC%2BC28XhsFGitbrN, PID: 27222544
    • Rubino F, Nathan D, Eckel R et al (2016) Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations. Diabetes Care 39:861–877
    • (2016) Diabetes Care , vol.39 , pp. 861-877
    • Rubino, F.1    Nathan, D.2    Eckel, R.3
  • 8
    • 84877946805 scopus 로고    scopus 로고
    • Metabolic effects of bariatric surgery in patients with moderate obesity and type 2 diabetes: analysis of a randomized control trial comparing surgery with intensive medical treatment
    • COI: 1:CAS:528:DC%2BC3sXhtlOrsrfJ, PID: 23439632
    • Kashyap SR, Bhatt DL, Wolski K et al (2013) Metabolic effects of bariatric surgery in patients with moderate obesity and type 2 diabetes: analysis of a randomized control trial comparing surgery with intensive medical treatment. Diabetes Care 36:2175–2182
    • (2013) Diabetes Care , vol.36 , pp. 2175-2182
    • Kashyap, S.R.1    Bhatt, D.L.2    Wolski, K.3
  • 9
    • 36048950771 scopus 로고    scopus 로고
    • Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding
    • PID: 17936091
    • Korner J, Bessler M, Inabnet W, Taveras C, Holst JJ (2007) Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding. Surg Obes Relat Dis 3:597–601
    • (2007) Surg Obes Relat Dis , vol.3 , pp. 597-601
    • Korner, J.1    Bessler, M.2    Inabnet, W.3    Taveras, C.4    Holst, J.J.5
  • 10
    • 84995380335 scopus 로고    scopus 로고
    • Mechanisms of surgical control of type 2 diabetes: GLP-1 is key factor
    • PID: 27313194
    • Holst J, Madsbad S (2016) Mechanisms of surgical control of type 2 diabetes: GLP-1 is key factor. Surg Obes Relat Dis 12:1236–1242
    • (2016) Surg Obes Relat Dis , vol.12 , pp. 1236-1242
    • Holst, J.1    Madsbad, S.2
  • 11
    • 84995377835 scopus 로고    scopus 로고
    • GLP-1 is not the key mediator of the health benefits of metabolic surgery
    • PID: 27313195
    • Vidal J, De Hollanda A, Jiménez A (2016) GLP-1 is not the key mediator of the health benefits of metabolic surgery. Surg Obes Relat Dis 12:1225–1229
    • (2016) Surg Obes Relat Dis , vol.12 , pp. 1225-1229
    • Vidal, J.1    De Hollanda, A.2    Jiménez, A.3
  • 12
    • 77957653654 scopus 로고    scopus 로고
    • Nationwide cohort study of post-gastric bypass hypoglycaemia including 5,040 patients undergoing surgery for obesity in 1986-2006 in Sweden
    • COI: 1:STN:280:DC%2BC3cflsVykuw%3D%3D, PID: 20495972
    • Marsk R, Jonas E, Rasmussen F, Naslund E (2010) Nationwide cohort study of post-gastric bypass hypoglycaemia including 5,040 patients undergoing surgery for obesity in 1986-2006 in Sweden. Diabetologia 53:2307–2311
    • (2010) Diabetologia , vol.53 , pp. 2307-2311
    • Marsk, R.1    Jonas, E.2    Rasmussen, F.3    Naslund, E.4
  • 13
    • 47549098811 scopus 로고    scopus 로고
    • Postgastric bypass hyperinsulinemic hypoglycaemia syndrome: characterization and response to a modified diet
    • Kellog TA, Bantle JP, Leslie DB et al (2008) Postgastric bypass hyperinsulinemic hypoglycaemia syndrome: characterization and response to a modified diet. Surg Obes Relat Dis 4:492–499
    • (2008) Surg Obes Relat Dis , vol.4 , pp. 492-499
    • Kellog, T.A.1    Bantle, J.P.2    Leslie, D.B.3
  • 14
    • 84959411933 scopus 로고    scopus 로고
    • Prevalence of self-reported symptoms after gastric bypass surgery for obesity
    • PID: 26747510
    • Gribsholt SB, Pedersen AM, Svensson E, Thomsen RW, Richelsen B (2016) Prevalence of self-reported symptoms after gastric bypass surgery for obesity. JAMA Surg 151:504–511
    • (2016) JAMA Surg , vol.151 , pp. 504-511
    • Gribsholt, S.B.1    Pedersen, A.M.2    Svensson, E.3    Thomsen, R.W.4    Richelsen, B.5
  • 15
    • 84931573728 scopus 로고    scopus 로고
    • Hypoglycemia after Roux-En-Y gastric bypass: detection rates of continuous glucose monitoring (CGM) versus mixed meal test
    • PID: 25737101
    • Kefurt R, Langer FB, Schindler K et al (2015) Hypoglycemia after Roux-En-Y gastric bypass: detection rates of continuous glucose monitoring (CGM) versus mixed meal test. Surg Obes Relat Dis 11:564–569
    • (2015) Surg Obes Relat Dis , vol.11 , pp. 564-569
    • Kefurt, R.1    Langer, F.B.2    Schindler, K.3
  • 16
    • 84861810088 scopus 로고    scopus 로고
    • Acarbose improves hypoglycaemia following gastric bypass surgery without increasing glucagon-like peptide 1 levels
    • PID: 22161170
    • Valderas J, Ahuad J, Rubio L, Escalona M, Pollak F, Maiz A (2012) Acarbose improves hypoglycaemia following gastric bypass surgery without increasing glucagon-like peptide 1 levels. Obes Surg 22:582–586
    • (2012) Obes Surg , vol.22 , pp. 582-586
    • Valderas, J.1    Ahuad, J.2    Rubio, L.3    Escalona, M.4    Pollak, F.5    Maiz, A.6
  • 17
    • 69249211012 scopus 로고    scopus 로고
    • Successful medical management of status post-Roux-en-Y-gastric-bypass hyperinsulinemic hypoglycaemia
    • PID: 19551453
    • Spanakis E, Gragnoli C (2009) Successful medical management of status post-Roux-en-Y-gastric-bypass hyperinsulinemic hypoglycaemia. Obes Surg 19:1333–1334
    • (2009) Obes Surg , vol.19 , pp. 1333-1334
    • Spanakis, E.1    Gragnoli, C.2
  • 18
    • 56549106949 scopus 로고    scopus 로고
    • Post-prandial hypoglycaemia after bariatric surgery: pharmacological treatment with verapamil and acarbose
    • PID: 18566871
    • Moreira R, Moreira R, Machado N, Gonçalves T, Coutinho W (2008) Post-prandial hypoglycaemia after bariatric surgery: pharmacological treatment with verapamil and acarbose. Obes Surg 18:1618–1621
    • (2008) Obes Surg , vol.18 , pp. 1618-1621
    • Moreira, R.1    Moreira, R.2    Machado, N.3    Gonçalves, T.4    Coutinho, W.5
  • 19
    • 77951624099 scopus 로고    scopus 로고
    • Reversible hyperinsulinemic hypoglycaemia after gastric bypass: a consequence of altered nutrient delivery
    • COI: 1:CAS:528:DC%2BC3cXltFSnsL0%3D, PID: 20133462
    • McLaughlin TL, Peck M, Holst JJ, Deacon C (2010) Reversible hyperinsulinemic hypoglycaemia after gastric bypass: a consequence of altered nutrient delivery. J Clin Endocrinol Metab 95:1851–1855
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1851-1855
    • McLaughlin, T.L.1    Peck, M.2    Holst, J.J.3    Deacon, C.4
  • 20
    • 85011851886 scopus 로고    scopus 로고
    • The use of gastrostomy tube for the long-term remission of hyperinsulinemic hypoglycaemia after Roux-en-Y gastric bypass – a case report
    • Craig C, Lamendola C, Deacon C, Holst J, McLaughlin T (2015) The use of gastrostomy tube for the long-term remission of hyperinsulinemic hypoglycaemia after Roux-en-Y gastric bypass – a case report. AACE Clin Case Rep 1:e84–e87
    • (2015) AACE Clin Case Rep , vol.1 , pp. e84-e87
    • Craig, C.1    Lamendola, C.2    Deacon, C.3    Holst, J.4    McLaughlin, T.5
  • 21
    • 74349085546 scopus 로고    scopus 로고
    • Peroral endoscopic anastomotic reduction improves intractable dumping syndrome in Roux-en-Y gastric bypass patients
    • Fernández-Esparrach G, Lautz D, Thompson C (2016) Peroral endoscopic anastomotic reduction improves intractable dumping syndrome in Roux-en-Y gastric bypass patients. Surg Obes Relat Dis 6:36–40
    • (2016) Surg Obes Relat Dis , vol.6 , pp. 36-40
    • Fernández-Esparrach, G.1    Lautz, D.2    Thompson, C.3
  • 22
    • 84879924641 scopus 로고    scopus 로고
    • Hormonal response to a mixed-meal challenge after reversal of gastric bypass for hypoglycaemia
    • Lee CJ, Brown T, Magnuson TH et al (2013) Hormonal response to a mixed-meal challenge after reversal of gastric bypass for hypoglycaemia. J Clin Endocrinol Metab 98:1208–1212
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 1208-1212
    • Lee, C.J.1    Brown, T.2    Magnuson, T.H.3
  • 23
    • 79957795474 scopus 로고    scopus 로고
    • Trends in hospital volume and operative mortality for high-risk surgery
    • COI: 1:CAS:528:DC%2BC3MXnt1Cmt7c%3D, PID: 21631325
    • Finks JF, Osborne NH, Birkmeyer JD (2011) Trends in hospital volume and operative mortality for high-risk surgery. N Engl J Med 364:2128–2137
    • (2011) N Engl J Med , vol.364 , pp. 2128-2137
    • Finks, J.F.1    Osborne, N.H.2    Birkmeyer, J.D.3
  • 25
    • 77955688074 scopus 로고    scopus 로고
    • Glucose-stimulated insulin secretion in gastric bypass patients with hypoglycaemic syndrome: no evidence for inappropriate pancreatic beta cell function
    • PID: 20665189
    • Kim SH, Abbasi F, Lamendola C, Reaven GM, McLaughlin T (2010) Glucose-stimulated insulin secretion in gastric bypass patients with hypoglycaemic syndrome: no evidence for inappropriate pancreatic beta cell function. Obes Surg 20:1110–1116
    • (2010) Obes Surg , vol.20 , pp. 1110-1116
    • Kim, S.H.1    Abbasi, F.2    Lamendola, C.3    Reaven, G.M.4    McLaughlin, T.5
  • 26
    • 27744539718 scopus 로고    scopus 로고
    • Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia
    • COI: 1:STN:280:DC%2BD2MngsVamug%3D%3D, PID: 16195867
    • Patti ME, McMahon G, Mun EC et al (2005) Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia. Diabetologia 48:2236–2240
    • (2005) Diabetologia , vol.48 , pp. 2236-2240
    • Patti, M.E.1    McMahon, G.2    Mun, E.C.3
  • 27
    • 79960088798 scopus 로고    scopus 로고
    • Changes in glucose homeostasis after Roux-en-Y gastric bypass surgery for obesity at day three, two months, and one year after surgery: role of gut peptides
    • COI: 1:CAS:528:DC%2BC3MXptlSru7Y%3D, PID: 21543426
    • Falken Y, Hellstrom PM, Holst JJ, Nasund E (2011) Changes in glucose homeostasis after Roux-en-Y gastric bypass surgery for obesity at day three, two months, and one year after surgery: role of gut peptides. J Clin Endocrinol Metab 96:2227–2235
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 2227-2235
    • Falken, Y.1    Hellstrom, P.M.2    Holst, J.J.3    Nasund, E.4
  • 28
    • 84876804316 scopus 로고    scopus 로고
    • Relationships between gastric emptying, postprandial glycemia, and incretin hormones
    • COI: 1:CAS:528:DC%2BC3sXnslWrtrw%3D, PID: 23613599
    • Marathe CS, Rayner CK, Jones KL, Horowitz M (2013) Relationships between gastric emptying, postprandial glycemia, and incretin hormones. Diabetes Care 36:1396–1405
    • (2013) Diabetes Care , vol.36 , pp. 1396-1405
    • Marathe, C.S.1    Rayner, C.K.2    Jones, K.L.3    Horowitz, M.4
  • 29
    • 36849063201 scopus 로고    scopus 로고
    • Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal
    • COI: 1:CAS:528:DC%2BD1cXmslWhurY%3D, PID: 17895322
    • Goldfine A, Mun E, Devine E et al (2007) Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal. J Clin Endocrinol Metab 92:4678–4685
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 4678-4685
    • Goldfine, A.1    Mun, E.2    Devine, E.3
  • 30
    • 85050579587 scopus 로고    scopus 로고
    • Differences in weight loss and gut hormones: Roux-en-Y gastric bypass and sleeve gastrectomy surgery
    • PID: 26627222
    • Malin SK, Kashyap SR (2015) Differences in weight loss and gut hormones: Roux-en-Y gastric bypass and sleeve gastrectomy surgery. Curr Obes Rep 4:279–286
    • (2015) Curr Obes Rep , vol.4 , pp. 279-286
    • Malin, S.K.1    Kashyap, S.R.2
  • 31
    • 79961204682 scopus 로고    scopus 로고
    • Gastric bypass surgery enhances glucagon-like peptide-1 stimulated postprandial insulin secretion in humans
    • COI: 1:CAS:528:DC%2BC3MXhtFymsbjO, PID: 21868791
    • Salehi M, Prigeon RL, D’Alessio DA (2011) Gastric bypass surgery enhances glucagon-like peptide-1 stimulated postprandial insulin secretion in humans. Diabetes 60:2308–2314
    • (2011) Diabetes , vol.60 , pp. 2308-2314
    • Salehi, M.1    Prigeon, R.L.2    D’Alessio, D.A.3
  • 32
    • 84894293729 scopus 로고    scopus 로고
    • Blockade of glucagon-like peptide 1 receptor corrects postprandial hypoglycaemia after gastric bypass
    • COI: 1:CAS:528:DC%2BC2cXislKitbw%3D, PID: 24315990
    • Salehi M, Gastaldelli A, D’Alessio D (2014) Blockade of glucagon-like peptide 1 receptor corrects postprandial hypoglycaemia after gastric bypass. Gastroenterology 146:669–680
    • (2014) Gastroenterology , vol.146 , pp. 669-680
    • Salehi, M.1    Gastaldelli, A.2    D’Alessio, D.3
  • 33
    • 0141446274 scopus 로고    scopus 로고
    • Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans
    • COI: 1:CAS:528:DC%2BD3sXosF2js7k%3D, PID: 14514592
    • Ahren B, Holst JJ, Mari A (2003) Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans. Diabetes Care 26:2860–2864
    • (2003) Diabetes Care , vol.26 , pp. 2860-2864
    • Ahren, B.1    Holst, J.J.2    Mari, A.3
  • 34
    • 0027305240 scopus 로고
    • Partitioning the symptoms of hypoglycaemia using multi-sample confirmatory factor analysis
    • COI: 1:STN:280:DyaK2c%2FhtVSjsA%3D%3D, PID: 8405746
    • Deary IJ, Hepburn DA, MacLeod KM, Frier BM (1993) Partitioning the symptoms of hypoglycaemia using multi-sample confirmatory factor analysis. Diabetologia 36:771–777
    • (1993) Diabetologia , vol.36 , pp. 771-777
    • Deary, I.J.1    Hepburn, D.A.2    MacLeod, K.M.3    Frier, B.M.4
  • 35
    • 0026048413 scopus 로고
    • Symptoms of acute insulin-induced hypoglycaemia in humans with and without IDDM
    • COI: 1:STN:280:DyaK387otlGmtg%3D%3D, PID: 1797507
    • Hepburn DA, Deary IJ, Frier BM, Patrick AW, Quinn JD, Fisher BM (1991) Symptoms of acute insulin-induced hypoglycaemia in humans with and without IDDM. Diabetes Care 14:949–957
    • (1991) Diabetes Care , vol.14 , pp. 949-957
    • Hepburn, D.A.1    Deary, I.J.2    Frier, B.M.3    Patrick, A.W.4    Quinn, J.D.5    Fisher, B.M.6
  • 36
    • 0028281773 scopus 로고
    • Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans
    • COI: 1:CAS:528:DyaK2cXitlKlt7c%3D, PID: 8138058
    • Orskov C, Rabenhøj L, Wettergren A, Kofod H, Holst JJ (1994) Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans. Diabetes 43:535–539
    • (1994) Diabetes , vol.43 , pp. 535-539
    • Orskov, C.1    Rabenhøj, L.2    Wettergren, A.3    Kofod, H.4    Holst, J.J.5
  • 37
    • 79961244091 scopus 로고    scopus 로고
    • Incretin hormone and insulin responses to oral vs intravenous lipid administration in humans
    • COI: 1:CAS:528:DC%2BC3MXhtVKhsb7K, PID: 21593115
    • Lindgren O, Carr RD, Deacon CF et al (2011) Incretin hormone and insulin responses to oral vs intravenous lipid administration in humans. J Clin Endocrinol Metab 96:2519–2524
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 2519-2524
    • Lindgren, O.1    Carr, R.D.2    Deacon, C.F.3
  • 38
    • 79959415768 scopus 로고    scopus 로고
    • Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual β-cell function
    • COI: 1:CAS:528:DC%2BC3MXmsVKlu7Y%3D, PID: 21441444
    • Kielgast U, Holst JJ, Madsbad S (2011) Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual β-cell function. Diabetes 60:1599–1607
    • (2011) Diabetes , vol.60 , pp. 1599-1607
    • Kielgast, U.1    Holst, J.J.2    Madsbad, S.3
  • 39
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man
    • COI: 1:CAS:528:DyaL2MXlslKnu7k%3D, PID: 3899825
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412–419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 40
    • 33646342516 scopus 로고    scopus 로고
    • Impact of differences in fasting glucose and glucose tolerance on the hyperbolic relationship between insulin sensitivity and insulin responses
    • PID: 16443887
    • Utzschneider KM, Prigeon RL, Carr DB et al (2006) Impact of differences in fasting glucose and glucose tolerance on the hyperbolic relationship between insulin sensitivity and insulin responses. Diabetes Care 29:356–362
    • (2006) Diabetes Care , vol.29 , pp. 356-362
    • Utzschneider, K.M.1    Prigeon, R.L.2    Carr, D.B.3
  • 41
    • 0030219807 scopus 로고    scopus 로고
    • ISEC: a program to calculate insulin secretion
    • COI: 1:STN:280:DyaK2s%2FkvFKmtQ%3D%3D
    • Hovorka R, Soons PA, Young MA (1996) ISEC: a program to calculate insulin secretion. Comput Methods Prog Biomed 50:253–264
    • (1996) Comput Methods Prog Biomed , vol.50 , pp. 253-264
    • Hovorka, R.1    Soons, P.A.2    Young, M.A.3
  • 42
    • 0026504160 scopus 로고
    • Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance
    • PID: 1551497
    • Van Cauter E, Mestrez F, Sturis J, Polonsky KS (1992) Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes 41:368–377
    • (1992) Diabetes , vol.41 , pp. 368-377
    • Van Cauter, E.1    Mestrez, F.2    Sturis, J.3    Polonsky, K.S.4
  • 43
    • 0036889282 scopus 로고    scopus 로고
    • Meal and oral glucose tests for assessment of beta-cell function: modeling analysis in normal subjects
    • COI: 1:CAS:528:DC%2BD38XpslGjtbc%3D, PID: 12388151
    • Mari A, Schmitz O, Gastaldelli A, Oestergaard T, Nyholm B, Ferrannini E (2002) Meal and oral glucose tests for assessment of beta-cell function: modeling analysis in normal subjects. Am J Physiol Endocrinol Metab 283:E1159–E1166
    • (2002) Am J Physiol Endocrinol Metab , vol.283 , pp. E1159-E1166
    • Mari, A.1    Schmitz, O.2    Gastaldelli, A.3    Oestergaard, T.4    Nyholm, B.5    Ferrannini, E.6
  • 44
    • 84907068044 scopus 로고    scopus 로고
    • Selectivity of peptide ligands for the human incretin receptors expressed in HEK-293 cells
    • COI: 1:CAS:528:DC%2BC2cXhsFWgsrnE, PID: 25179575
    • Al-Sabah S, Al-Fulaij M, Ahmed HA (2014) Selectivity of peptide ligands for the human incretin receptors expressed in HEK-293 cells. Eur J Pharmacol 741:311–315
    • (2014) Eur J Pharmacol , vol.741 , pp. 311-315
    • Al-Sabah, S.1    Al-Fulaij, M.2    Ahmed, H.A.3
  • 45
    • 0037312821 scopus 로고    scopus 로고
    • The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects
    • COI: 1:CAS:528:DC%2BD3sXhtFans7w%3D, PID: 12540611
    • Kjems LL, Holst JJ, Volund A, Madsbad S (2003) The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects. Diabetes 52:380–386
    • (2003) Diabetes , vol.52 , pp. 380-386
    • Kjems, L.L.1    Holst, J.J.2    Volund, A.3    Madsbad, S.4
  • 46
    • 84885469835 scopus 로고    scopus 로고
    • GLP-1 action and glucose tolerance in participants with remission of type 2 diabetes after gastric bypass surgery
    • COI: 1:CAS:528:DC%2BC3sXhtF2jtbbE, PID: 23359363
    • Jimenez A, Casamitjana R, Viaplana-Masclans J, Lacy A, Vidal J (2013) GLP-1 action and glucose tolerance in participants with remission of type 2 diabetes after gastric bypass surgery. Diabetes Care 36:2062–2069
    • (2013) Diabetes Care , vol.36 , pp. 2062-2069
    • Jimenez, A.1    Casamitjana, R.2    Viaplana-Masclans, J.3    Lacy, A.4    Vidal, J.5
  • 47
    • 0019736655 scopus 로고
    • The diagnosis of postprandial hypoglycaemia
    • COI: 1:STN:280:DyaL38%2FntlGhsg%3D%3D, PID: 7308588
    • Lev-Ran A, Anderson RW (1981) The diagnosis of postprandial hypoglycaemia. Diabetes 30:996–999
    • (1981) Diabetes , vol.30 , pp. 996-999
    • Lev-Ran, A.1    Anderson, R.W.2
  • 48
    • 0026019648 scopus 로고
    • Hierarchy of glycaemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction
    • COI: 1:CAS:528:DyaK3MXhsVSrtLY%3D, PID: 1987794
    • Mitrakou A, Ryan C, Veneman T et al (1991) Hierarchy of glycaemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction. Am J Physiol 260:E67–E74
    • (1991) Am J Physiol , vol.260 , pp. E67-E74
    • Mitrakou, A.1    Ryan, C.2    Veneman, T.3


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