Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression

EBioMedicine

Volumn 14, Issue , 2016, Pages 161-167

  Zeng, Yanni ^a   Navarro, Pau ^b   Xia, Charley ^b   Amador, Carmen ^b   Fernandez Pujals, Ana M ^a   Thomson, Pippa A ^a   Campbell, Archie ^a   Nagy, Reka ^b   Clarke, Toni Kim ^a   Hafferty, Jonathan D ^a   Smith, Blair H ^a,c   Hocking, Lynne J ^a,d   Padmanabhan, Sandosh ^a,e   Hayward, Caroline ^b   MacIntyre, Donald J ^a   Porteous, David J ^a   Haley, Chris S ^b,f   McIntosh, Andrew M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

^f UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Couple effect; Family environment; Linear mixed modeling; Major depressive disorder; Self declared depression; SNP heritability

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENVIRONMENTAL FACTOR; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; HERITABILITY; HUMAN; MAJOR DEPRESSION; MALE; MAXIMUM LIKELIHOOD METHOD; MIDDLE AGED; PEDIGREE; PEDIGREE ANALYSIS; PHENOTYPIC VARIATION; PRIORITY JOURNAL; RISK FACTOR; SELF DECLARED DEPRESSION; SIBLING RELATION; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURED CLINICAL INTERVIEW FOR DSM DISORDERS; DEPRESSION; DEPRESSIVE DISORDER, MAJOR; ENVIRONMENT; GENETIC PREDISPOSITION; GENOTYPE; PHENOTYPE; RISK; SELF REPORT; STATISTICAL MODEL;

DEPRESSION; DEPRESSIVE DISORDER, MAJOR; ENVIRONMENT; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MODELS, STATISTICAL; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK; SELF REPORT;

EID: 85004075743     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2016.11.003     Document Type: Article

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