Ulcerative colitis and Crohn’s disease are associated with decreased serum selenium concentrations and increased cardiovascular risk

Nutrients

Volumn 8, Issue 12, 2016, Pages

  Aguilar Tablada, Teresa Castro ^a,b   Navarro Alarcón, Miguel ^b   Granados, Javier Quesada ^b   Sánchez, Cristina Samaniego ^b   Rufián Henares, José Ángel ^b,c   Nogueras Lopez, Flor ^d  

^a HOSPITAL DE JEREZ   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

^c UNIVERSITY OF GRANADA   (Spain)

^d Granada Hospital Complex   (Spain)

Author keywords

Crohn s disease; Influencing factors; Nutritional and biochemical markers; Selenium; Ulcerative colitis

Indexed keywords

ACETYLSALICYLIC ACID; ALBUMIN; ALPHA 1 ANTITRYPSIN; C REACTIVE PROTEIN; CHOLESTEROL; CHOLINESTERASE; CORTICOSTEROID; HEMOGLOBIN; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; IRON; OROSOMUCOID; POTASSIUM; BIOLOGICAL MARKER; SELENIUM; SERPINA1 PROTEIN, HUMAN;

ADULT; ARTICLE; BLOOD SAMPLING; BODY MASS; CARDIOVASCULAR RISK; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HEMATOCRIT; HUMAN; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NUTRITIONAL PARAMETERS; SELENIUM BLOOD LEVEL; ULCERATIVE COLITIS; BLOOD; CARDIOVASCULAR DISEASES; COLITIS, ULCERATIVE; COMPARATIVE STUDY; COMPLICATION; DEFICIENCY; DIET THERAPY; DISEASE COURSE; GENERAL HOSPITAL; MALNUTRITION; NUTRITIONAL DEFICIENCY; NUTRITIONAL STATUS; OBESITY; PATHOPHYSIOLOGY; POPULATION DYNAMICS; RISK; SEVERITY OF ILLNESS INDEX; SEX DIFFERENCE; SPAIN;

ADULT; ALPHA 1-ANTITRYPSIN; BIOMARKERS; BODY MASS INDEX; CARDIOVASCULAR DISEASES; COLITIS, ULCERATIVE; CROHN DISEASE; DEFICIENCY DISEASES; DISEASE PROGRESSION; FEMALE; HEALTH TRANSITION; HOSPITALS, GENERAL; HUMANS; MALE; MALNUTRITION; NUTRITIONAL STATUS; OBESITY; RISK; SELENIUM; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SPAIN;

EID: 85003811021     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu8120780     Document Type: Article

References (26)

1. Barnett, M.; Bermingham, E.; McNabb, W.; Basset, S.; Armstrong, K.; Rounce, J.; Roy, N. Investigating micronutrients and epigenetic mechanisms in relation to inflammatory bowel disease. Mutat. Res. 2010, 690, 71-80.
2. Cabré Gelada, E.; Gassull Duro, M.A. Nutrición en la enfermedad inflamatoria intestinal. In Tratado de Nutrición, Tomo IV; Gil, A., Ed.; Editorial Medica Panamericana: Madrid, Spain, 2010; pp. 669-687.
3. Salari, P. New horizons in management of inflammatory bowel disease. Intern. J. Pharmacol. 2011, 7, 679-681.
4. 2 induction. Free Radic. Biol. Med. 2010, 49, 777-785.
5. Gentschew, L.; Bishop, K.S.; Yeo Han, D.; Morgan, A.R.; Fraser, A.G.; Jiun Lam, W.; Karunasinghe, N.; Campbell, B.; Ferguson, L.R. Selenium, selenoprotein genes and Crhon’s disease in a case -control population from Auckland, New Zealand. Nutrients 2012, 4, 1247-1249.
6. Narayan, V.; Ravindra, K.C.; Liao, C.; Kaushal, N.; Carlson, B.A.; Prabhu, K.S. Epigenetic regulation of inflammatory gene expression in macrophages by selenium. J. Nutr. Biochem. 2015, 26, 138-145.
7. Barret, C.W.; Reddy, V.K.; Short, S.P.; Motley, A.K.; Lintel, M.K.; Bradley, A.M.; Freeman, T.; Vallance, J.; Ning, W.; Parang, B. et al. Selenoprotein P influences colitis-induced tumorigenesis by mediating and oxidative damage. J. Clin. Investig. 2016, 125, 2646-2660.
8. Navarro-Alarcón, M.; Cabrera-Vique, C. Selenium in food and human body: A review. Sci. Total Environ. 2008, 400, 115-141.
9. Joseph, J.; Loscalzo, J. Selenistasis: Epistatic effects of selenium on cardiovascular phenotype. Nutrients 2013, 5, 340-358.
10. Benstoem, C.; Goetzenich, A.; Kraemer, S.; Borosch, S.; Manzanares, W.; Hardy, G.; Stoppe, C. Selenium and its supplementation in cardiovascular disease-What do we know? Nutrients 2015, 7, 3094-3118.
11. Finley, J.W.; Davis, C.D. Selenium (Se) from high-selenium broccoli is utilized differently than selenite, selenate and selenomethionine, but is more effective in inhibiting colon carcinogenesis. Biofactors 2001, 14, 191-196.
12. Tirosh, O.; Levy, E.; Reifen, R. High selenium diet protects against TNBS-induced acute inflammation mitochondrial dysfunction and secondary necrosis in rat colon. Nutrition 2007, 23, 878-886.
13. Bitiren, M.; Karakilcik, A.Z.; Zerin, M.; Ozardah, I.; Selek, S.; Nazhgül, Y.; Ozgonul, A.; Musa, D.; Uzunkoy, A. Protective effects of selenium and vitamin E combination on experimental colitis in blood plasma and colon of rats. Biol. Trace Elem. Res. 2010, 136, 87-95.
14. Kaushal, N.; Kudva, A.K.; Patterson, A.D.; Chiaro, C.; Kennett, M.J.; Desai, D.; Amin, S.; Carlson, B.A.; Cantorna, M.T.; Prabhu, K.S. Crucial role of macrophage selenoproteins in experimental colitis. J. Immunol. 2014, 193, 3683-3692.
15. Kudva, A.K.; Shay, A.E.; Prabhu, K.S. Selenium and inflammatory disease. Am. J. Physiol. Gastroenterol. Liver Physiol. 2015, 309, G71-G77.
16. Ringstad, J.; Kildebo, S.; Thomassen, Y. Serum selenium, copper and zinc concentrations in Crhon’s disease and ulcerative colitis. Scand. J. Gastroenterol. 1993, 28, 605-608.
17. Geerling, B.J.; Badart-Smook, A.; Stockbrügger, R.W.; Brummer, R.J. Comprehensive nutritional status in recently diagnosed patients with inflammatory bowel disease compared with population controls. Eur. J. Clin. Nutr. 2000, 54, 514-521.
18. Barret, C.W.; Singh, K.; Motley, A.K.; Lintel, M.K.; Matafonova, E.; Bradlley, A.M.; Ning, W.; Pondexter, S.V.; Parang, B.; Reddy, V.K. et al. Dietary selenium deficiency exacerbats DSS-induce epithelial injury and AOM/DSS-inducedtumorigenesis. PLoS ONE 2013, 8, e67845.
19. Andoh, A.; Hirashima, M.; Maeda, H.; Hata, K.; Inatomi, O.; Tsujikawa, T.; Sasaki, M.; Takahashi, K.; Fujiyama, Y. Serum selenoprotein-P levels in patients with inflammatory bowel disease. Nutrition 2005, 21, 574-579.
20. Nelson, S.M.; Lei, X.; Prabhu, K.S. Selenium levels affect the IL-4-induced expression of alternative activation markers in murine macrophages. J. Nutr. 2011, 141, 1754-1761.
21. Combs, G.F., Jr. Biomarkers of selenium status. Nutrients 2015, 7, 2209-2236.
22. Navarro, M.; Lopez, H.; Ruiz, M.L.; Gonzalez, S.; Perez, V.; Lopez, M.C. Determination of selenium in serum by hydride generation atomic absorption spectrometry for calculation of daily dietary intake. Sci. Total Environ. 1995, 175, 245-252.
23. Navarro, M.; López, H.; Perez, V.; López, M.C. Serum selenium levels during normal pregnancy in healthy Spanish women. Sci. Total Environ. 1996, 186, 237-242.
24. Silverberg, M.S.; Satsangi, J.; Ahmad, T.; Arnott, I.D.; Bernstein, C.N.; Brant, S.R.; Caprilli, R.; Colombel, J.F.; Gasche, C.; Geboes, K. et al. Towards an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a working party for the 2005 Montreal World Congress of gastroenterology. Can. J. Gastroenterol. 2005, 19, A5-A36.
25. Sikora, S.K.; Spady, D.; Prosser, C.; El-Matary, W. Trace elements and vitamins at diagnosis in pediatric-onset inflammatory bowel disease. Clin. Pediatr. 2011, 50, 488-492.
26. Weishoof, R.; Chermesh, I. Micronutrient deficiencies in inflammatory bowel disease. Curr. Opin. Clin. Nutr. Metab. Care 2015, 18, 576-581.