Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases

Molecular Oncology

Volumn 10, Issue 10, 2016, Pages 1575-

  Beije, Nick ^a   Helmijr, Jean C ^a   Weerts, Marjolein J A ^a   Beaufort, Corine M ^a   Wiggin, Matthew ^b   Marziali, Andre ^b   Verhoef, Cornelis ^a   Sleijfer, Stefan ^a   Jansen, Maurice P H M ^a   Martens, John W M ^a  

^a ERASMUS MC CANCER INSTITUTE   (Netherlands)

^b Boreal Genomics Inc   (Canada)

Author keywords

Cell free DNA; Circulating tumor DNA; Metastatic colorectal cancer; Next generation sequencing; Somatic mutations

Indexed keywords

APC PROTEIN; ATM PROTEIN; BETA ACTIN; CELL FREE DNA; CHLOROPLAST DNA; CIRCULATING TUMOR DNA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DNA; DNA FRAGMENT; K RAS PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P53; UNCLASSIFIED DRUG; URACIL DNA GLYCOSIDASE;

ALLELE; ARTICLE; CANCER PATIENT; CIRCULATING TUMOR CELL; CLINICAL ARTICLE; COLON; COLORECTAL LIVER METASTASIS; CONTROLLED STUDY; DNA ISOLATION; GENE FREQUENCY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIMIT OF DETECTION; LIVER; LIVER RESECTION; METASTASIS RESECTION; METASTATIC COLORECTAL CANCER; PRIMARY TUMOR; PRIORITY JOURNAL; SOMATIC MUTATION;

EID: 85003554412     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2016.10.001     Document Type: Article

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