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1 Sarbagili-Shabat, C., Sigall-Boneh, R., Levine, A., Nutritional therapy in inflammatory bowel disease. Curr Opin Gastroenterol 31 (2015), 303–308.
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This review presented currently available and emerging therapeutic options in modulating composition and metabolic activity of gut microbiota in patients with inflammatory bowel disease.
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4 Lorente-Cebrián, S., Costa, A.G., Navas-Carretero, S., Zabala, M., Laiglesia, L.M., Martínez, J.A., Moreno-Aliaga, M.J., An update on the role of omega-3 fatty acids on inflammatory and degenerative diseases. J Physiol Biochem 71 (2015), 341–349.
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8 Yamamoto, T., Nutrition and diet in inflammatory bowel disease. Curr Opin Gastroenterol 29 (2013), 216–221.
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This study showed evidence available on the clinical effects of probiotics and prebiotics in Crohn's disease and clarified the place of probiotic treatment in current therapeutic regimens.
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9•• Lichtenstein, L., Avni-Biron, I., Ben-Bassat, O., Probiotics and prebiotics in Crohn's disease therapies. Best Pract Res Clin Gastroenterol 30 (2016), 81–88 This study showed evidence available on the clinical effects of probiotics and prebiotics in Crohn's disease and clarified the place of probiotic treatment in current therapeutic regimens.
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Lichtenstein, L.1
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10 Schultz, M., Timmer, A., Herfarth, H.H., Sartor, R.B., Vanderhoof, J.A., Rath, H.C., Lactobacillus GG in inducing and maintaining remission of Crohn's disease. BMC Gastroenterol, 4, 2004, 5.
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11 Schultz, M., Linde, H.J., Lehn, N., Zimmermann, K., Grossmann, J., Falk, W., Schölmerich, J., Immunomodulatory consequences of oral administration of Lactobacillus rhamnosus strain GG in healthy volunteers. J Dairy Res 70 (2003), 165–173.
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12 Fujiya, M., Ueno, N., Kohgo, Y., Probiotic treatments for induction and maintenance of remission in inflammatory bowel diseases: a meta-analysis of randomized controlled trials. Clin J Gastroenterol 7 (2014), 1–13.
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13 Shen, J., Zuo, Z.X., Mao, A.P., Effect of probiotics on inducing remission and maintaining therapy in ulcerative colitis, Crohn's disease, and pouchitis: meta-analysis of randomized controlled trials. Inflamm Bowel Dis 20 (2014), 21–35.
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14 Ghouri, Y.A., Richards, D.M., Rahimi, E.F., Krill, J.T., Jelinek, K.A., DuPont, A.W., Systematic review of randomized controlled trials of probiotics, prebiotics, and synbiotics in inflammatory bowel disease. Clin Exp Gastroenterol 7 (2014), 473–487.
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16 Rolfe, V.E., Fortun, P.J., Hawkey, C.J., Bath-Hextall, F., Probiotics for maintenance of remission in Crohn's disease. Cochrane Database Syst Rev, 4, 2006, CD004826.
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18 Scott, K.P., Martin, J.C., Duncan, S.H., Flint, H.J., Prebiotic stimulation of human colonic butyrate-producing bacteria and bifidobacteria, in vitro. FEMS Microbiol Ecol 87 (2014), 30–40.
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19 Lindsay, J.O., Whelan, K., Stagg, A.J., Gobin, P., Al-Hassi, H.O., Rayment, N., Kamm, M.A., Knight, S.C., Forbes, A., Clinical, microbiological, and immunological effects of fructo-oligosaccharide in patients with Crohn's disease. Gut 55 (2006), 348–355.
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20 Hafer, A., Krämer, S., Duncker, S., Krüger, M., Manns, M.P., Bischoff, S.C., Effect of oral lactulose on clinical and immunohistochemical parameters in patients with inflammatory bowel disease: a pilot study. BMC Gastroenterol, 7, 2007, 36.
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Effect of oligofructose-enriched inulin (OF-IN) on bacterial composition and disease activity of patients with Crohn's disease: results from a double-blinded randomised controlled trial
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21 Joossens, M., De Preter, V., Ballet, V., Verbeke, K., Rutgeerts, P., Vermeire, S., Effect of oligofructose-enriched inulin (OF-IN) on bacterial composition and disease activity of patients with Crohn's disease: results from a double-blinded randomised controlled trial. Gut, 61, 2012, 958.
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22 Benjamin, J.L., Hedin, C.R., Koutsoumpas, A., Ng, S.C., McCarthy, N.E., Hart, A.L., Kamm, M.A., Sanderson, J.D., Knight, S.C., Forbes, A., et al. Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease. Gut 60 (2011), 923–929.
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This study provides evidence that the specific carbohydrate diet may improve clinical and laboratory parameters for pediatric patients with inflammatory bowel disease.
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This study systematically reviewed the efficacy of omega 3 fatty acids for maintenance of remission in Crohn's disease and found that they are probably ineffective.
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26 Feagan, B.G., Sandborn, W.J., Mittmann, U., Bar-Meir, S., D'Haens, G., Bradette, M., Cohen, A., Dallaire, C., Ponich, T.P., McDonald, J.W., et al. Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC Randomized Controlled Trials. JAMA 299 (2008), 1690–1697.
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27 Akobeng, A.K., Miller, V., Stanton, J., Elbadri, A.M., Thomas, A.G., Double-blind randomized controlled trial of glutamine-enriched polymeric diet in the treatment of active Crohn's disease. J Pediatr Gastroenterol Nutr 30 (2000), 78–84.
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28 Ockenga, J., Borchert, K., Stüber, E., Lochs, H., Manns, M.P., Bischoff, S.C., Glutamine-enriched total parenteral nutrition in patients with inflammatory bowel disease. Eur J Clin Nutr 59 (2005), 1302–1309.
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This study evaluated the efficacy of glutamine supplementation for induction of remission in Crohn's disease and found that it may not be beneficial.
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33 Yamamoto, T., Nakahigashi, M., Umegae, S., Kitagawa, T., Matsumoto, K., Impact of elemental diet on mucosal inflammation in patients with active Crohn's disease: cytokine production and endoscopic and histological findings. Inflamm Bowel Dis 11 (2005), 580–588.
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35 Berni Canani, R., Terrin, G., Borrelli, O., Romano, M.T., Manguso, F., Coruzzo, A., D'Armiento, F., Romeo, E.F., Cucchiara, S., Short- and long-term therapeutic efficacy of nutritional therapy and corticosteroids in paediatric Crohn's disease. Dig Liver Dis 38 (2006), 381–387.
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38 Takagi, S., Utsunomiya, K., Kuriyama, S., Yokoyama, H., Takahashi, S., Iwabuchi, M., Takahashi, H., Takahashi, S., Kinouchi, Y., Hiwatashi, N., et al. Effectiveness of an ‘half elemental diet’ as maintenance therapy for Crohn's disease: a randomized-controlled trial. Aliment Pharmacol Ther 24 (2006), 1333–1340.
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