Impact of elemental diet on mucosal inflammation in patients with active Crohn's disease: Cytokine production and endoscopic and histological findings

Inflammatory Bowel Diseases

Volumn 11, Issue 6, 2005, Pages 580-588

  Yamamoto, Takayuki ^a   Nakahigashi, Maki ^a   Umegae, Satoru ^a   Kitagawa, Tatsushi ^a   Matsumoto, Koichi ^a  

^a MIE UNIVERSITY   (Japan)

Author keywords

Crohn's disease; Cytokine; Elemental diet; Mucosal inflammation

Indexed keywords

CORTICOSTEROID; CYTOKINE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; INTRALIPID; MESALAZINE; PREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CALORIC INTAKE; CLINICAL ARTICLE; CLINICAL TRIAL; COLIC; COLON MUCOSA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; DIARRHEA; DIET THERAPY; DISEASE ACTIVITY; ELEMENTAL DIET; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTROINTESTINAL ENDOSCOPY; HEALING; HISTOPATHOLOGY; HUMAN; ILEUM MUCOSA; INTESTINE BIOPSY; MALE; MUCOSA INFLAMMATION; PRIORITY JOURNAL; REMISSION; SINGLE BLIND PROCEDURE; TREATMENT OUTCOME;

ADULT; BIOPSY; CROHN DISEASE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FOOD, FORMULATED; HUMANS; INFLAMMATION; INTESTINAL MUCOSA; MALE; PARENTERAL NUTRITION; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 20444447446     PISSN: 10780998     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.MIB.0000161307.58327.96     Document Type: Article

References (39)

1. Kanof ME, Lake AM, Bayless TM. Decreased height velocity in children and adolescents before the diagnosis of Crohn's disease. Gastroenterology. 1988;95:1523-1527.
2. Stokes MA. Crohn's disease and nutrition. Br J Surg. 1992;79:391-394.
3. Giorgini GL, Stephens RV, Thayer WR. The use of 'medical bypass' in the therapy of Crohn's disease: report of a case. Am J Dig Dis. 1973;18:153-157.
4. Axelsson C, Jarnum S. Assessment of the therapeutic value of an elemental diet in chronic inflammatory bowel disease. Scand J Gastroenterol. 1977;77:89-95.
5. O'Morain C, Segal AW, Levi AJ. Elemental diet in the treatment of acute Crohn's disease. BMJ. 1980;281:1173-1175.
6. O'Morain C, Segal AW, Levi AJ. Elemental diet as primary treatment of acute Crohn's disease: a controlled trial. BMJ. 1984;288:1859-1862.
7. Okada M, Yao T, Yamamoto K, et al. Controlled trial comparing an elemental diet with prednisolone in the treatment of active Crohn's disease. Hepatogastroenterology. 1990;37:72-80.
8. Saverymuttu S, Hodgson HJF, Chadwick VS. Controlled trial comparing prednisolone with an elemental diet plus non-absorbable antibiotics in active Crohn's disease. Gut. 1985;26:994-998.
9. Gorard DA, Hunt JB, Payne-James JJ, et al. Initial response and subsequent course of Crohn's disease treated with elemental diet or prednisolone. Gut. 1993;34:1198-1202.
10. Malchow H, Steinhardt HJ, Lorenz-Meyer H, et al. Feasibility and effectiveness of a defined-formula diet regimen in treating active Crohn's disease. European Cooperative Crohn's Disease Study III. Scand J Gastroenterol. 1990;25:235-244.
11. Lochs H, Steinhardt HJ, Klaus-Wentz B, et al. Comparison of enteral nutrition and drug treatment in active Crohn's disease: results of the European Cooperative Crohn's Disease Study IV. Gastroenterology. 1991;101:881-888.
12. Lindor KD, Fleming CR, Burnes JU, et al. A randomized prospective trial comparing a defined formula diet, corticosteroids, and a defined formula diet plus corticosteroids in active Crohn's disease. Mayo Clin Proc. 1992;67:328-333.
13. Griffiths AM, Ohlsson A, Sherman PM, et al. Meta-analysis of enteral nutrition as a primary treatment of active Crohn's disease. Gastroenterology. 1995;108:1056-1067.
14. Fernández-Bañares F, Cabré E, Esteve-Comas M, et al. How effective is enteral nutrition in inducing clinical remission in active Crohn's disease? A meta-analysis of the randomized clinical trials. JPEN J Parenter Enteral Nutr. 1995;19:356-364.
15. Heuschkel RB, Menache CC, Megerian JT, et al. Enteral nutrition and corticosteroids in the treatment of acute Crohn's disease in children. J Pediatr Gastroenterol Nutr. 2000;31:8-15.
16. Sanderson IR, Boulton P, Menzies I, et al. Improvement of abnormal lactulose-rhamnose permeability in active Crohn's disease of the small bowel by an elemental diet. Gut. 1987;28:1073-1076.
17. Morain CO, Segal AA, Walker D, et al. Abnormalities of neutrophil function do not cause the migration defect in Crohn's disease. Gut. 1981; 22:817-822.
18. Crowther JS, Drasar BS, Goddard P, et al. The effect of a chemically defined diet in the faecal flora and faecal steroid concentration. Gut. 1973; 14:790-793.
19. Winitz M, Adams RF, Seedman DA, et al. Studies in metabolic nutrition employing chemically defined diets. II. Effects on gut microflora populations. Am J Clin Nutr. 1970;23:546-559.
20. Reinecker HC, Steffen M, Witthoeft T, et al. Enhanced secretion of tumor necrosis factor-alpha, IL-6, and IL-1β by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin Exp Immunol. 1993;94:174-181.
21. Breese EJ, Michie CA, Nicholls SW, et al. Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology. 1994;106:1455-1466.
22. Reimund J-M, Wittersheim C, Dumont S, et al. Increased production of tumour necrosis factor-α, interleukin-1β, and interleukin-6 by morphologically normal intestinal biopsies from patients with Crohn's disease. Gut. 1996;39:684-689.
23. Raab Y, Gerdin B, Ahlstedt S, et al. Neutrophil mucosal involvement is accompanied by enhanced local production of interleukin-8 in ulcerative colitis. Gut. 1993;34:1203-1206.
24. Casini-Raggi V, Kam L, Chong YJT, et al. Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation. J Immunol. 1995;154: 2434-2440.
25. Cominelli F, Pizarro TT. Interleukin-1 and interleukin-1 receptor antagonist in inflammatory bowel disease. Aliment Pharmacol Ther. 1996;10(Suppl. 2):49-53.
26. Dionne S, D'Agata ID, Hiscott J, et al. Colonic explant production of IL-1 and its receptor antagonist is imbalanced in inflammatory bowel disease (IBD). Clin Exp Immunol. 1998;112:435-442.
27. Rogler G, Andus T. Cytokines in inflammatory bowel disease. World J Surg. 1998;22:382-389.
28. Breese EJ, Michie CA, Nicholls SW, et al. The effect of treatment on lymphokine-secreting cells in the intestinal mucosa of children with Crohn's disease. Aliment Pharmacol Ther. 1995;9:547-552.
29. Ferguson A, Glen M, Ghosh S. Crohn's disease: nutrition and nutritional therapy. Ballieres Clin Gastroenterol. 1998;12:93-114.
30. Fell JM, Paintin M, Arnaud-Battandier F, et al. Mucosal healing and a fall in mucosal pro-inflammatory cytokine mRNA induced by a specific oral polymeric diet in paediatric Crohn's disease. Aliment Pharmacol Ther. 2000;14:281-289.
31. Meister D, Bode J, Shand A, et al. Anti-inflammatory effects of enteral diet components on Crohn's disease-affected tissues in vitro. Dig Liver Dis. 2002;34:430-438.
32. Best WR, Becktel JM, Singleton JW, et al. Development of a Crohn's disease activity index: National Cooperative Crohn's Disease Study. Gastroenterology. 1976;70:439-444.
33. Wardle TD, Hall L, Turnberg LA. Use of coculture of colonic mucosal biopsies to investigate the release of eicosanoids by inflamed and uninflamed mucosa from patients with inflammatory bowel disease. Gut. 1992;33:1644-1651.
34. Saverymuttu SH, Camilleri M, Rees H, et al. Indium III-granulocyte scanning in the assessment of disease extent and disease activity in inflammatory bowel disease: a comparison with colonoscopy, histology, and fecal indium III-granulocyte excretion. Gastroenterology. 1986;90: 1121-1128.
35. Teahon K, Bjarnason I, Pearson M, et al. Ten years' experience with an elemental diet in the management of Crohn's disease. Gut. 1990;31:1133-1137.
36. Zurita VF, Rawls DE, Dyck WP. Nutritional support in inflammatory bowel disease. Dig Dis. 1995;13:92-107.
37. King TS, Woolner JT, Hunter JO. Review article: the dietary management of Crohn's disease. Aliment Pharmacol Ther. 1997;11:17-31.
38. Fernández-Bañares F, Cabré E, González-Huix F, et al. Enteral nutrition as primary therapy in Crohn's disease. Gut. 1994;35(Suppl 1):S55-S59.
39. Middleton SJ, Rucker JT, Kirby GA, et al. Long chain triglycerides reduce the efficacy of enteral feeds in patients with active Crohn's disease. Clin Nutr: 1995;14:229-236.