-
1
-
-
84873309581
-
-
Centers for Disease Control, Prevention. Public Health Genomics Accessed 5 August 2015
-
Centers for Disease Control, Prevention. Public Health Genomics. Genomic Tests, Family History by Levels of Evidence. www.cdc.gov/genomics/gtesting/tier.htm. Accessed 5 August 2015.
-
Genomic Tests, Family History by Levels of Evidence
-
-
-
2
-
-
78649630180
-
Evidence-based classification of recommendations on use of genomic tests in clinical practice: Dealing with insufficient evidence
-
Khoury MJ, Coates RJ, Evans JP. Evidence-based classification of recommendations on use of genomic tests in clinical practice: dealing with insufficient evidence. Genet Med 2010;12:680-683.
-
(2010)
Genet Med
, vol.12
, pp. 680-683
-
-
Khoury, M.J.1
Coates, R.J.2
Evans, J.P.3
-
3
-
-
37349116252
-
The continuum of translation research in genomic medicine: How can we accelerate the appropriate integration of human genome discoveries into health care disease prevention
-
Khoury MJ, Gwinn M, Yoon PW, Dowling N, Moore CA, Bradley L. The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care, disease prevention Genet Med 2007;9:665-674.
-
(2007)
Genet Med
, vol.9
, pp. 665-674
-
-
Khoury, M.J.1
Gwinn, M.2
Yoon, P.W.3
Dowling, N.4
Moore, C.A.5
Bradley, L.6
-
4
-
-
77956258041
-
Translational research in cancer genetics: The road less traveled
-
Schully SD, Benedicto CB, Gillanders EM, Wang SS, Khoury MJ. Translational research in cancer genetics: the road less traveled. Public Health Genom 2011;14:1-8.
-
(2011)
Public Health Genom
, vol.14
, pp. 1-8
-
-
Schully, S.D.1
Benedicto, C.B.2
Gillanders, E.M.3
Wang, S.S.4
Khoury, M.J.5
-
5
-
-
84861793170
-
Multilevel research, the challenges of implementing genomic medicine
-
Khoury MJ, Coates RJ, Fennell ML, et al. Multilevel research, the challenges of implementing genomic medicine. J Natl Cancer Inst Monogr 2012;2012:112-120.
-
(2012)
J Natl Cancer Inst Monogr
, vol.2012
, pp. 112-120
-
-
Khoury, M.J.1
Coates, R.J.2
Fennell, M.L.3
-
6
-
-
84988369742
-
-
Oxford University Press: Oxford, UK
-
Drummond MF, Sculpher MJ, Torrance GW, O'Brien BJ, Stoddart GL. Methods for the Economic Evaluation of Health Care Programmes, 3rd edn. Oxford University Press: Oxford, UK, 2005.
-
(2005)
Methods for the Economic Evaluation of Health Care Programmes, 3rd Edn
-
-
Drummond, M.F.1
Sculpher, M.J.2
Torrance, G.W.3
O'Brien, B.J.4
Stoddart, G.L.5
-
7
-
-
0033740880
-
Prevalence penetrance of BRCA1, BRCA2 mutations in a population-based series of breast cancer cases
-
Anglian Breast Cancer Study Group
-
Anglian Breast Cancer Study Group. Prevalence, penetrance of BRCA1, BRCA2 mutations in a population-based series of breast cancer cases. Br J Cancer 2000;83:1301-1308.
-
(2000)
Br J Cancer
, vol.83
, pp. 1301-1308
-
-
-
8
-
-
29144509766
-
BRCA1, BRCA2 mutations account for a large proportion of ovarian carcinoma cases
-
Pal T, Permuth-Wey J, Betts JA, et al. BRCA1, BRCA2 mutations account for a large proportion of ovarian carcinoma cases. Cancer 2005;104:2807-2816.
-
(2005)
Cancer
, vol.104
, pp. 2807-2816
-
-
Pal, T.1
Permuth-Wey, J.2
Betts, J.A.3
-
9
-
-
33845654907
-
Population BRCA1, BRCA2 mutation frequencies, cancer penetrances: A kin-cohort study in Ontario, Canada
-
Risch HA, McLaughlin JR, Cole DE, et al. Population BRCA1, BRCA2 mutation frequencies, cancer penetrances: a kin-cohort study in Ontario, Canada. J Natl Cancer Inst 2006;98:1694-1706.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1694-1706
-
-
Risch, H.A.1
McLaughlin, J.R.2
Cole, D.E.3
-
10
-
-
85000447302
-
-
Ministry of Health Accessed 5 August 2015
-
Ministry of Health. 2014-2018 National Prevention Plan, Italy. www.salute.gov. it/portale/documentazione/p6-2-2-1.jsplingua=italiano&id=2285. Accessed 5 August 2015.
-
2014-2018 National Prevention Plan, Italy
-
-
-
11
-
-
76149089524
-
Systematic reviews of economic evaluations: Utility or futility
-
Anderson R. Systematic reviews of economic evaluations: utility or futility Health Econ 2010;19:350-364.
-
(2010)
Health Econ
, vol.19
, pp. 350-364
-
-
Anderson, R.1
-
12
-
-
67651035065
-
Systematic reviews of economic evaluations
-
Centre for Reviews, Dissemination (CRD) CRD: York, UK
-
Centre for Reviews, Dissemination (CRD). Systematic reviews of economic evaluations. In: Systematic Reviews: CRD's Guidance for Undertaking Reviews in Health Care. CRD: York, UK, 2009.
-
(2009)
Systematic Reviews: CRD's Guidance for Undertaking Reviews in Health Care
-
-
-
13
-
-
84890675397
-
Incorporating economics evidence
-
Higgins JPT, Green S (eds) The Cochrane Collaboration
-
Shemilt I, Mugford M, Byford S, et al. Incorporating economics evidence. In: Higgins JPT, Green S (eds). Cochrane Handbook for Systematic Reviews of Interventions, version 5.1.0. The Cochrane Collaboration, 2011. http://handbook.cochrane.org/
-
(2011)
Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0
-
-
Shemilt, I.1
Mugford, M.2
Byford, S.3
-
14
-
-
0030056579
-
Guidelines for authors, peer reviewers of economic submissions to the BMJ. The BMJ Economic Evaluation Working Party
-
Drummond MF, Jefferson TO. Guidelines for authors, peer reviewers of economic submissions to the BMJ. The BMJ Economic Evaluation Working Party. BMJ 1996;313:275-283.
-
(1996)
BMJ
, vol.313
, pp. 275-283
-
-
Drummond, M.F.1
Jefferson, T.O.2
-
15
-
-
0037268757
-
Development, validation of a grading system for the quality of cost-effectiveness studies
-
Chiou CF, Hay JW, Wallace JF, et al. Development, validation of a grading system for the quality of cost-effectiveness studies. Med Care 2003;41:32-44.
-
(2003)
Med Care
, vol.41
, pp. 32-44
-
-
Chiou, C.F.1
Hay, J.W.2
Wallace, J.F.3
-
16
-
-
84973587732
-
A coefficient of agreement for nominal scales
-
Cohen J. A coefficient of agreement for nominal scales. Educ Psychol Meas 1960;20:37-46.
-
(1960)
Educ Psychol Meas
, vol.20
, pp. 37-46
-
-
Cohen, J.1
-
17
-
-
84907360483
-
Updating cost-effectiveness-The curious resilience of the $50,000-per-QALY threshold
-
Neumann PJ, Cohen JT, Weinstein MC. Updating cost-effectiveness-The curious resilience of the $50,000-per-QALY threshold. N Engl J Med 2014;371:796-797.
-
(2014)
N Engl J Med
, vol.371
, pp. 796-797
-
-
Neumann, P.J.1
Cohen, J.T.2
Weinstein, M.C.3
-
18
-
-
84895787381
-
The economic value of personalized medicine tests: What we know, what we need to know
-
Phillips KA, Ann Sakowski J, Trosman J, Douglas MP, Liang SY, Neumann P. The economic value of personalized medicine tests: what we know, what we need to know. Genet Med 2014;16:251-257.
-
(2014)
Genet Med
, vol.16
, pp. 251-257
-
-
Phillips, K.A.1
Ann Sakowski, J.2
Trosman, J.3
Douglas, M.P.4
Liang, S.Y.5
Neumann, P.6
-
19
-
-
84923209923
-
Methods for the estimation of the NICE cost effectiveness threshold
-
Claxton K, Martin S, Soares M, et al. Methods for the estimation of the NICE cost effectiveness threshold. Health Technol Assess 2015;19(14):1-503.
-
(2015)
Health Technol Assess
, vol.19
, Issue.14
, pp. 1-503
-
-
Claxton, K.1
Martin, S.2
Soares, M.3
-
20
-
-
36049046788
-
-
Center for the Evaluation of Value, Risk in Health at the Institute for Clinical Research, Health Policy Studies Tufts Medical Center: Boston, MA Accessed 5 August 2015
-
Center for the Evaluation of Value, Risk in Health at the Institute for Clinical Research, Health Policy Studies. Cost-Effectiveness Analysis Registry (https://research.tufts-nemc.org/cear4/). Tufts Medical Center: Boston, MA, 2015. Accessed 5 August, 2015.
-
(2015)
Cost-Effectiveness Analysis Registry
-
-
-
21
-
-
0033015788
-
Benefits, costs of screening Ashkenazi Jewish women for BRCA1, BRCA2
-
Grann VR, Whang W, Jacobson JS, Heitjan DF, Antman KH, Neugut AI. Benefits, costs of screening Ashkenazi Jewish women for BRCA1, BRCA2. J Clin Oncol 1999;17:494-500.
-
(1999)
J Clin Oncol
, vol.17
, pp. 494-500
-
-
Grann, V.R.1
Whang, W.2
Jacobson, J.S.3
Heitjan, D.F.4
Antman, K.H.5
Neugut, A.I.6
-
22
-
-
0032757171
-
Costs, benefits of diagnosing familial breast cancer
-
Heimdal K, Maehle L, Møller P. Costs, benefits of diagnosing familial breast cancer. Dis Markers 1999;15:167-173.
-
(1999)
Dis Markers
, vol.15
, pp. 167-173
-
-
Heimdal, K.1
Maehle, L.2
Møller, P.3
-
23
-
-
0033997009
-
The cost effectiveness of testing for the BRCA1, BRCA2 breast-ovarian cancer susceptibility genes
-
Tengs TO, Berry DA. The cost effectiveness of testing for the BRCA1, BRCA2 breast-ovarian cancer susceptibility genes. Dis Manag Clin Outcomes 2000;1:15-24.
-
(2000)
Dis Manag Clin Outcomes
, vol.1
, pp. 15-24
-
-
Tengs, T.O.1
Berry, D.A.2
-
24
-
-
7044224630
-
Genetic counseling program in familial breast cancer: Analysis of its effectiveness, cost, cost-effectiveness ratio
-
Balmanã J, Sanz J, Bonfill X, et al. Genetic counseling program in familial breast cancer: analysis of its effectiveness, cost, cost-effectiveness ratio. Int J Cancer 2004;112:647-652.
-
(2004)
Int J Cancer
, vol.112
, pp. 647-652
-
-
Balmanã, J.1
Sanz, J.2
Bonfill, X.3
-
25
-
-
60349111615
-
Cost-effectiveness of testing for breast cancer susceptibility genes
-
Holland ML, Huston A, Noyes K. Cost-effectiveness of testing for breast cancer susceptibility genes. Value Health 2009;12:207-216.
-
(2009)
Value Health
, vol.12
, pp. 207-216
-
-
Holland, M.L.1
Huston, A.2
Noyes, K.3
-
26
-
-
77449112281
-
Preventing future cancers by testing women with ovarian cancer for BRCA mutations
-
Kwon JS, Daniels MS, Sun CC, Lu KH. Preventing future cancers by testing women with ovarian cancer for BRCA mutations. J Clin Oncol 2010;28: 675-682.
-
(2010)
J Clin Oncol
, vol.28
, pp. 675-682
-
-
Kwon, J.S.1
Daniels, M.S.2
Sun, C.C.3
Lu, K.H.4
-
27
-
-
70349665340
-
Cost-effectiveness of population-based BRCA1/2 testing, ovarian cancer prevention for Ashkenazi Jews: A call for dialogue
-
Rubinstein WS, Jiang H, Dellefave L, Rademaker AW. Cost-effectiveness of population-based BRCA1/2 testing, ovarian cancer prevention for Ashkenazi Jews: a call for dialogue. Genet Med 2009;11:629-639.
-
(2009)
Genet Med
, vol.11
, pp. 629-639
-
-
Rubinstein, W.S.1
Jiang, H.2
Dellefave, L.3
Rademaker, A.W.4
-
28
-
-
77957967823
-
Expanding the criteria for BRCA mutation testing in breast cancer survivors
-
Kwon JS, Gutierrez-Barrera AM, Young D, et al. Expanding the criteria for BRCA mutation testing in breast cancer survivors. J Clin Oncol 2010;28:4214-4220.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4214-4220
-
-
Kwon, J.S.1
Gutierrez-Barrera, A.M.2
Young, D.3
-
29
-
-
84922477275
-
Cost-effectiveness of population screening for BRCA mutations in Ashkenazi jewish women compared with family history-based testing
-
Manchanda R, Legood R, Burnell M, et al. Cost-effectiveness of population screening for BRCA mutations in Ashkenazi jewish women compared with family history-based testing. J Natl Cancer Inst 2015;107:380.
-
(2015)
J Natl Cancer Inst
, vol.107
, pp. 380
-
-
Manchanda, R.1
Legood, R.2
Burnell, M.3
-
30
-
-
68549101842
-
The PRISMA statement for reporting systematic reviews, meta-analyses of studies that evaluate healthcare interventions: Explanation, elaboration
-
Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews, meta-analyses of studies that evaluate healthcare interventions: explanation, elaboration. BMJ 2009;339:b2700.
-
(2009)
BMJ
, vol.339
, pp. b2700
-
-
Liberati, A.1
Altman, D.G.2
Tetzlaff, J.3
-
31
-
-
0030910022
-
The risk of cancer associated with specific mutations of BRCA1, BRCA2 among Ashkenazi Jews
-
Struewing JP, Hartge P, Wacholder S, et al. The risk of cancer associated with specific mutations of BRCA1, BRCA2 among Ashkenazi Jews. N Engl J Med 1997;336:1401-1408.
-
(1997)
N Engl J Med
, vol.336
, pp. 1401-1408
-
-
Struewing, J.P.1
Hartge, P.2
Wacholder, S.3
-
32
-
-
16044366988
-
The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%
-
Oddoux C, Struewing JP, Clayton CM, et al. The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%. Nat Genet 1996;14:188-190.
-
(1996)
Nat Genet
, vol.14
, pp. 188-190
-
-
Oddoux, C.1
Struewing, J.P.2
Clayton, C.M.3
-
33
-
-
16044366171
-
Frequency of recurrent BRCA1, BRCA2 mutations in Ashkenazi Jewish breast cancer families
-
Tonin P, Weber B, Offit K, et al. Frequency of recurrent BRCA1, BRCA2 mutations in Ashkenazi Jewish breast cancer families. Nat Med 1996;2: 1179-1183.
-
(1996)
Nat Med
, vol.2
, pp. 1179-1183
-
-
Tonin, P.1
Weber, B.2
Offit, K.3
-
34
-
-
1342282444
-
Population genetic screening programmes: Technical, social, ethical issues. Recommendations of the European Society of Human Genetics
-
European Society of Human Genetics (ESHG)
-
European Society of Human Genetics (ESHG). Population genetic screening programmes: technical, social, ethical issues. Recommendations of the European Society of Human Genetics. Eur J Hum Genet 2003;11:S5-S7.
-
(2003)
Eur J Hum Genet
, vol.11
, pp. S5-S7
-
-
-
35
-
-
0142156674
-
Economic considerations for health insurance coverage of emerging genetic tests
-
Giacomini M, Miller F, O'Brien BJ. Economic considerations for health insurance coverage of emerging genetic tests. Community Genet 2003;6:61-73.
-
(2003)
Community Genet
, vol.6
, pp. 61-73
-
-
Giacomini, M.1
Miller, F.2
O'Brien, B.J.3
-
37
-
-
33749155617
-
Genetic screening by DNA technology: A systematic review of health economic evidence
-
Rogowski W. Genetic screening by DNA technology: a systematic review of health economic evidence. Int J Technol Assess Health Care 2006;22:327-337.
-
(2006)
Int J Technol Assess Health Care
, vol.22
, pp. 327-337
-
-
Rogowski, W.1
-
38
-
-
79951569002
-
A review of economic evaluations of genetic testing services, interventions (2004-2009)
-
Djalalov S, Musa Z, Mendelson M, Siminovitch K, Hoch J. A review of economic evaluations of genetic testing services, interventions (2004-2009). Genet Med 2011;13:89-94.
-
(2011)
Genet Med
, vol.13
, pp. 89-94
-
-
Djalalov, S.1
Musa, Z.2
Mendelson, M.3
Siminovitch, K.4
Hoch, J.5
-
39
-
-
84868034874
-
Economic evaluations conducted for assessment of genetic testing technologies: A systematic review
-
Assasi N, Schwartz L, Tarride JE, Goeree R, Xie F. Economic evaluations conducted for assessment of genetic testing technologies: a systematic review. Genet Test Mol Biomarkers 2012;16:1322-1335.
-
(2012)
Genet Test Mol Biomarkers
, vol.16
, pp. 1322-1335
-
-
Assasi, N.1
Schwartz, L.2
Tarride, J.E.3
Goeree, R.4
Xie, F.5
-
40
-
-
84968919475
-
Genetic testing, economic evaluations: A systematic review of the literature
-
D'Andrea E, Marzuillo C, Pelone F, De Vito C, Villari P. Genetic testing, economic evaluations: a systematic review of the literature. Epidemiol Prev 2015;39(suppl 1):S45-S50.
-
(2015)
Epidemiol Prev
, vol.39
, pp. S45-S50
-
-
D'Andrea, E.1
Marzuillo, C.2
Pelone, F.3
De Vito, C.4
Villari, P.5
-
41
-
-
39049091057
-
Does preventive care save money Health economics, the presidential candidates
-
Cohen JT, Neumann PJ, Weinstein MC. Does preventive care save money Health economics, the presidential candidates. N Engl J Med 2008;358: 661-663.
-
(2008)
N Engl J Med
, vol.358
, pp. 661-663
-
-
Cohen, J.T.1
Neumann, P.J.2
Weinstein, M.C.3
-
42
-
-
84864263001
-
The cost-effectiveness of environmental approaches to disease prevention
-
Chokshi DA, Farley TA. The cost-effectiveness of environmental approaches to disease prevention. N Engl J Med 2012;367:295-297.
-
(2012)
N Engl J Med
, vol.367
, pp. 295-297
-
-
Chokshi, D.A.1
Farley, T.A.2
-
43
-
-
84862980777
-
Developing national guidance on genetic testing for breast cancer predisposition: The role of economic evidence
-
Sullivan W, Evans DG, Newman WG, Ramsden SC, Scheffer H, Payne K. Developing national guidance on genetic testing for breast cancer predisposition: the role of economic evidence Genet Test Mol Biomarkers 2012;16:580-591.
-
(2012)
Genet Test Mol Biomarkers
, vol.16
, pp. 580-591
-
-
Sullivan, W.1
Evans, D.G.2
Newman, W.G.3
Ramsden, S.C.4
Scheffer, H.5
Payne, K.6
-
44
-
-
84951907411
-
Cost-effectiveness of universal BRCA1/2 screening: Evidencebased decision making
-
Long EF, Ganz PA. Cost-effectiveness of universal BRCA1/2 screening: evidencebased decision making. JAMA Oncol 2015;3:1-2.
-
(2015)
JAMA Oncol
, vol.3
, pp. 1-2
-
-
Long, E.F.1
Ganz, P.A.2
-
45
-
-
83755225553
-
NCCN Task Force report: Evaluating the clinical utility of tumor markers in oncology
-
quiz S33
-
Febbo PG, Ladanyi M, Aldape KD, et al. NCCN Task Force report: evaluating the clinical utility of tumor markers in oncology. J Natl Compr Canc Netw 2011;9(suppl 5):S1-S32; quiz S33.
-
(2011)
J Natl Compr Canc Netw
, vol.9
, pp. S1-S32
-
-
Febbo, P.G.1
Ladanyi, M.2
Aldape, K.D.3
-
46
-
-
84894279437
-
-
US Preventive Services Task Force (USPSTF) Evidence Syntheses, No. 101. Agency for Healthcare Research, Quality (US): Rockville, MD
-
US Preventive Services Task Force (USPSTF). Risk Assessment, Genetic Counseling, Genetic Testing for BRCA-Related Cancer. Systematic Review to Update the US Preventive Services Task Force Recommendation. Evidence Syntheses, No. 101. Agency for Healthcare Research, Quality (US): Rockville, MD, 2013.
-
(2013)
Risk Assessment, Genetic Counseling, Genetic Testing for BRCA-Related Cancer. Systematic Review to Update the US Preventive Services Task Force Recommendation
-
-
-
47
-
-
78650158157
-
Awareness, utilization of BRCA1/2 testing among US primary care physicians
-
Bellcross CA, Kolor K, Goddard KA, Coates RJ, Reyes M, Khoury MJ. Awareness, utilization of BRCA1/2 testing among US primary care physicians. Am J Prev Med 2011;40:61-66.
-
(2011)
Am J Prev Med
, vol.40
, pp. 61-66
-
-
Bellcross, C.A.1
Kolor, K.2
Goddard, K.A.3
Coates, R.J.4
Reyes, M.5
Khoury, M.J.6
-
48
-
-
84885859313
-
Knowledge, attitudes, behavior of physicians regarding predictive genetic tests for breast, colorectal cancer
-
Marzuillo C, De Vito C, Boccia S, et al. Knowledge, attitudes, behavior of physicians regarding predictive genetic tests for breast, colorectal cancer. Prev Med 2013;57:477-482.
-
(2013)
Prev Med
, vol.57
, pp. 477-482
-
-
Marzuillo, C.1
De Vito, C.2
Boccia, S.3
-
49
-
-
84895798774
-
Economic analyses of genetic tests in personalized medicine: Clinical utility first, then cost utility
-
Grosse SD. Economic analyses of genetic tests in personalized medicine: clinical utility first, then cost utility. Genet Med 2014;16:225-227.
-
(2014)
Genet Med
, vol.16
, pp. 225-227
-
-
Grosse, S.D.1
-
50
-
-
77149122082
-
The cost-effectiveness of genetic testing strategies for Lynch syndrome among newly diagnosed patients with colorectal cancer
-
Mvundura M, Grosse SD, Hampel H, Palomaki GE. The cost-effectiveness of genetic testing strategies for Lynch syndrome among newly diagnosed patients with colorectal cancer. Genet Med 2010;12:93-104.
-
(2010)
Genet Med
, vol.12
, pp. 93-104
-
-
Mvundura, M.1
Grosse, S.D.2
Hampel, H.3
Palomaki, G.E.4
-
51
-
-
79960604164
-
Strategies to identify the Lynch syndrome among patients with colorectal cancer: A cost-effectiveness analysis
-
Ladabaum U, Wang G, Terdiman J, et al. Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis. Ann Intern Med 2011;155:69-79.
-
(2011)
Ann Intern Med
, vol.155
, pp. 69-79
-
-
Ladabaum, U.1
Wang, G.2
Terdiman, J.3
|