A Multi-Center Review of Care Patterns and Outcomes in Necrotizing Soft Tissue Infections

Surgical Infections

Volumn 17, Issue 6, 2016, Pages 773-778

  Faraklas, Iris ^a   Yang, Derek ^b   Eggerstedt, Michael ^c   Zhai, Yan ^a   Liebel, Patrick ^a   Graves, Gareth ^a   Dissanaike, Sharmila ^b   Mosier, Michael ^c   Cochran, Amalia ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

antibiotic therapy; necrotizing fasciitis; necrotizing soft tissue infection; outcomes

Indexed keywords

ADULT; ANTIBIOTIC THERAPY; ANTIMICROBIAL AGENT INITIATION; APACHE; ARTICLE; BODY MASS; CLINICAL PRACTICE; COMORBIDITY; DEBRIDEMENT; DEMOGRAPHY; DIABETES MELLITUS; EVIDENCE BASED PRACTICE; FEMALE; HEALTH CARE CONCEPTS; HOSPITAL ACQUIRED PNEUMONIA; HOSPITAL INFECTION; HOSPITAL READMISSION; HUMAN; HYPERTENSION; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORTALITY; MULTICENTER STUDY (TOPIC); NECROTIZING SOFT TISSUE INFECTION; OUTCOME ASSESSMENT; PATIENT TRANSPORT; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SKIN NECROSIS; SMOKING; SOFT TISSUE INFECTION; SURVIVAL RATE; SURVIVAL TIME; TREATMENT DURATION; TREND STUDY; URINARY TRACT INFECTION; CLINICAL TRIAL; FASCIITIS, NECROTIZING; KAPLAN MEIER METHOD; MULTICENTER STUDY; SOFT TISSUE INFECTIONS; TREATMENT OUTCOME;

ANTIINFECTIVE AGENT;

ADULT; ANTI-BACTERIAL AGENTS; FASCIITIS, NECROTIZING; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SOFT TISSUE INFECTIONS; TREATMENT OUTCOME;

EID: 85000417103     PISSN: 10962964     EISSN: 15578674     Source Type: Journal    
DOI: 10.1089/sur.2015.238     Document Type: Article

References (17)

1. Sarani B, Strong M, Pascual J, Schwab CW. Necrotizing fasciitis: Current concepts and review of the literature. J Am Coll Surg 2009;208:279-288. http://www.science direct.com/science/article/pii/S1072751508015469 (last accessed October 7, 2016).
2. Mills MK, Farakl as I, Davis C, et al. Outcomes from treatment of necrotizing soft-tissue infections: Results from the National Surgical Quality Improvement Program database. Am J Surg 2010;200:790-796.
3. Holena DN, Mills AM, Carr BG, et al. Transfer status: A risk factor for mortality in patients with necrotizing fas-ciitis. Surgery 2011;150:363-370.
4. Stevens DL, Bis no AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis 2005;41:1373-1406.
5. Chastre J, Wolff M, Fagon JY, et al. Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: A randomized trial. JAMA 2003;290: 2588-2598.
6. Kao LS, Lew DF, Arab SN, et al. Local variations in the epidemiology, microbiology, and outcome of necrotizing soft-tissue infections: A multicenter study. Am J Surg 2011; 202:139-145.
7. Eggerstedt M, Gamelli RL, Mosier MJ. The care of nec-rotizing soft-tissue infections: Patterns of definitive intervention at a large referral center. J Burn Care Res 2015; 36:105-110.
8. Anaya DA, Bulger EM, Kwon YS, et al. Predicting death in necrotizing soft tissue infections: A clinical score. Surg Infect 2009;10:517-522.
9. Faraklas I, Stoddard GJ, Neumayer LA, Cochran A. Development and validation of a necrotizing soft-tissue infection mortality risk calculator using NSQIP. J Am Coll Surg 2013;217:153-160.
10. Bulger EM, Maier R V, Sperry J, Joshi M, Henry S, Moore FA, et al. A novel drug for treatment of necrotizing soft-tissue infections: A randomized clinical trial. JAMA Surg 2014;149:528-536.
11. Brown DR, Davis NL, Lepawsky M, et al. A multicenter review of the treatment of major truncal necrotizing infections with and without hyperbaric oxygen therapy. Am J Surg 1994;167:485-489.
12. Harris PA, Taylor R, Thielke R, et al. Research electronic data capture (REDCap)-a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 2009;42:377-381.
13. Bernal NP, Latenser BA, Born JM, Liao J. Trends in 393 necrotizing acute soft tissue infection patients 2000-2008. Burns 2012;38:252-260.
14. McHenry CR, Piotrowski JJ, Petrinic D, Malangoni MA. Determinants of mortality for necrotizing soft-tissue infections. Ann Surg 1995;221:558-563.
15. Elliott D, Kufera JA, Myers RA. The microbiology of necrotizing soft tissue infections. Am J Surg 2000;179: 361-366.
16. Gunter OL, Guillamondegui OD, May AK, Diaz JJ. Outcome of necrotizing skin and soft tissue infections. Surg Infect 2008;9:443-450.
17. Endorf FW, Klein MB, Mack CD, et al. Necrotizing soft-tissue infections: Differences in patients treated at burn centers and non-burn centers.J Burn Care Res 2008;29:933-938.