-
1
-
-
84953856186
-
FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: Updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study
-
Cremolini C, Loupakis F, Antoniotti C, Lupi C, Sensi E, Lonardi S, Mezi S, Tomasello G, Ronzoni M, Zaniboni A, Tonini G, Carlomagno C, Allegrini G, Chiara S, D'Amico M, Granetto C, Cazzaniga M, Boni L, Fontanini G, Falcone A: FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study. Lancet Oncol 2015;16:1306-1315.
-
(2015)
Lancet Oncol
, vol.16
, pp. 1306-1315
-
-
Cremolini, C.1
Loupakis, F.2
Antoniotti, C.3
Lupi, C.4
Sensi, E.5
Lonardi, S.6
Mezi, S.7
Tomasello, G.8
Ronzoni, M.9
Zaniboni, A.10
Tonini, G.11
Carlomagno, C.12
Allegrini, G.13
Chiara, S.14
D'Amico, M.15
Granetto, C.16
Cazzaniga, M.17
Boni, L.18
Fontanini, G.19
Falcone, A.20
more..
-
2
-
-
84930047088
-
FOLFOX4 plus cetuximab treatment and RAS mutations in colorectal cancer
-
Bokemeyer C, Kohne CH, Ciardiello F, Lenz HJ, Heinemann V, Klinkhardt U, Beier F, Duecker K, van Krieken JH, Tejpar S: FOLFOX4 plus cetuximab treatment and RAS mutations in colorectal cancer. Eur J Cancer 2015;51:1243-1252.
-
(2015)
Eur J Cancer
, vol.51
, pp. 1243-1252
-
-
Bokemeyer, C.1
Kohne, C.H.2
Ciardiello, F.3
Lenz, H.J.4
Heinemann, V.5
Klinkhardt, U.6
Beier, F.7
Duecker, K.8
Van Krieken, J.H.9
Tejpar, S.10
-
3
-
-
84925324704
-
Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer
-
Van Cutsem E, Lenz HJ, Kohne CH, Heinemann V, Tejpar S, Melezinek I, Beier F, Stroh C, Rougier P, van Krieken JH, Ciardiello F: Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer. J Clin Oncol 2015;33:692-700.
-
(2015)
J Clin Oncol
, vol.33
, pp. 692-700
-
-
Van Cutsem, E.1
Lenz, H.J.2
Kohne, C.H.3
Heinemann, V.4
Tejpar, S.5
Melezinek, I.6
Beier, F.7
Stroh, C.8
Rougier, P.9
Van Krieken, J.H.10
Ciardiello, F.11
-
4
-
-
84883680951
-
Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer
-
Douillard JY, Oliner KS, Siena S, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, Rivera F, Kocakova I, Ruff P, Blasinska-Morawiec M, Smakal M, Canon JL, Rother M, Williams R, Rong A, Wiezorek J, Sidhu R, Patterson SD: Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 2013;369:1023-1034.
-
(2013)
N Engl J Med
, vol.369
, pp. 1023-1034
-
-
Douillard, J.Y.1
Oliner, K.S.2
Siena, S.3
Tabernero, J.4
Burkes, R.5
Barugel, M.6
Humblet, Y.7
Bodoky, G.8
Cunningham, D.9
Jassem, J.10
Rivera, F.11
Kocakova, I.12
Ruff, P.13
Blasinska-Morawiec, M.14
Smakal, M.15
Canon, J.L.16
Rother, M.17
Williams, R.18
Rong, A.19
Wiezorek, J.20
Sidhu, R.21
Patterson, S.D.22
more..
-
5
-
-
84907594273
-
The role of antiangiogenic agents in the treatment of patients with advanced colorectal cancer according to K-RAS status
-
Garcia-Alfonso P, Grande E, Polo E, Afonso R, Reina JJ, Jorge M, Campos JM, Martinez V, Angeles C, Montagut C: The role of antiangiogenic agents in the treatment of patients with advanced colorectal cancer according to K-RAS status. Angiogenesis 2014;17:805-821.
-
(2014)
Angiogenesis
, vol.17
, pp. 805-821
-
-
Garcia-Alfonso, P.1
Grande, E.2
Polo, E.3
Afonso, R.4
Reina, J.J.5
Jorge, M.6
Campos, J.M.7
Martinez, V.8
Angeles, C.9
Montagut, C.10
-
6
-
-
84986893153
-
Primary tumour resection could improve the survival of unresectable metastatic colorectal cancer patients receiving bevacizumab-containing chemotherapy
-
Wang Z, Liang L, Yu Y, Wang Y, Zhuang R, Chen Y, Cui Y, Zhou Y, Liu T: Primary Tumour Resection Could Improve the Survival of Unresectable Metastatic Colorectal Cancer Patients Receiving Bevacizumab-Containing Chemotherapy. Cell Physiol Biochem 2016;39:1239-1246.
-
(2016)
Cell Physiol Biochem
, vol.39
, pp. 1239-1246
-
-
Wang, Z.1
Liang, L.2
Yu, Y.3
Wang, Y.4
Zhuang, R.5
Chen, Y.6
Cui, Y.7
Zhou, Y.8
Liu, T.9
-
7
-
-
84908573757
-
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): A randomised, open-label, phase 3 trial
-
Heinemann V, von Weikersthal LF, Decker T, Kiani A, Vehling-Kaiser U, Al-Batran SE, Heintges T, Lerchenmuller C, Kahl C, Seipelt G, Kullmann F, Stauch M, Scheithauer W, Hielscher J, Scholz M, Muller S, Link H, Niederle N, Rost A, Hoffkes HG, Moehler M, Lindig RU, Modest DP, Rossius L, Kirchner T, Jung A, Stintzing S: FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial. Lancet Oncol 2014;15:1065-1075.
-
(2014)
Lancet Oncol
, vol.15
, pp. 1065-1075
-
-
Heinemann, V.1
Von Weikersthal, L.F.2
Decker, T.3
Kiani, A.4
Vehling-Kaiser, U.5
Al-Batran, S.E.6
Heintges, T.7
Lerchenmuller, C.8
Kahl, C.9
Seipelt, G.10
Kullmann, F.11
Stauch, M.12
Scheithauer, W.13
Hielscher, J.14
Scholz, M.15
Muller, S.16
Link, H.17
Niederle, N.18
Rost, A.19
Hoffkes, H.G.20
Moehler, M.21
Lindig, R.U.22
Modest, D.P.23
Rossius, L.24
Kirchner, T.25
Jung, A.26
Stintzing, S.27
more..
-
8
-
-
84905870196
-
PEAK: A randomized, multicenter phase II study of panitumumab plus modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) or bevacizumab plus mFOLFOX6 in patients with previously untreated, unresectable, wild-type KRAS exon 2 metastatic colorectal cancer
-
Schwartzberg LS, Rivera F, Karthaus M, Fasola G, Canon JL, Hecht JR, Yu H, Oliner KS, Go WY: PEAK: a randomized, multicenter phase II study of panitumumab plus modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) or bevacizumab plus mFOLFOX6 in patients with previously untreated, unresectable, wild-type KRAS exon 2 metastatic colorectal cancer. J Clin Oncol 2014;32:2240-2247.
-
(2014)
J Clin Oncol
, vol.32
, pp. 2240-2247
-
-
Schwartzberg, L.S.1
Rivera, F.2
Karthaus, M.3
Fasola, G.4
Canon, J.L.5
Hecht, J.R.6
Yu, H.7
Oliner, K.S.8
Go, W.Y.9
-
9
-
-
61449202998
-
The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: Analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer
-
Hurwitz HI, Yi J, Ince W, Novotny WF, Rosen O: The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer. Oncologist 2009;14:22-28.
-
(2009)
Oncologist
, vol.14
, pp. 22-28
-
-
Hurwitz, H.I.1
Yi, J.2
Ince, W.3
Novotny, W.F.4
Rosen, O.5
-
10
-
-
78149250536
-
Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study
-
Douillard JY, Siena S, Cassidy J, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, Rivera F, Kocakova I, Ruff P, Blasinska-Morawiec M, Smakal M, Canon JL, Rother M, Oliner KS, Wolf M, Gansert J: Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 2010;28:4697-4705.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
Tabernero, J.4
Burkes, R.5
Barugel, M.6
Humblet, Y.7
Bodoky, G.8
Cunningham, D.9
Jassem, J.10
Rivera, F.11
Kocakova, I.12
Ruff, P.13
Blasinska-Morawiec, M.14
Smakal, M.15
Canon, J.L.16
Rother, M.17
Oliner, K.S.18
Wolf, M.19
Gansert, J.20
more..
-
11
-
-
79956310674
-
Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: The OPUS study
-
Bokemeyer C, Bondarenko I, Hartmann JT, de Braud F, Schuch G, Zubel A, Celik I, Schlichting M, Koralewski P: Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. Ann Oncol 2011;22:1535-1546.
-
(2011)
Ann Oncol
, vol.22
, pp. 1535-1546
-
-
Bokemeyer, C.1
Bondarenko, I.2
Hartmann, J.T.3
De Braud, F.4
Schuch, G.5
Zubel, A.6
Celik, I.7
Schlichting, M.8
Koralewski, P.9
-
12
-
-
79956298812
-
Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status
-
Van Cutsem E, Kohne CH, Lang I, Folprecht G, Nowacki MP, Cascinu S, Shchepotin I, Maurel J, Cunningham D, Tejpar S, Schlichting M, Zubel A, Celik I, Rougier P, Ciardiello F: Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J Clin Oncol 2011;29:2011-2019.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2011-2019
-
-
Van Cutsem, E.1
Kohne, C.H.2
Lang, I.3
Folprecht, G.4
Nowacki, M.P.5
Cascinu, S.6
Shchepotin, I.7
Maurel, J.8
Cunningham, D.9
Tejpar, S.10
Schlichting, M.11
Zubel, A.12
Celik, I.13
Rougier, P.14
Ciardiello, F.15
-
13
-
-
84861318872
-
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer-subgroup analysis of patients with KRAS: Mutated tumours in the randomised German AIO study KRK-0306
-
Stintzing S, Fischer von Weikersthal L, Decker T, Vehling-Kaiser U, Jager E, Heintges T, Stoll C, Giessen C, Modest DP, Neumann J, Jung A, Kirchner T, Scheithauer W, Heinemann V: FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer-subgroup analysis of patients with KRAS: mutated tumours in the randomised German AIO study KRK-0306. Ann Oncol 2012;23:1693-1699.
-
(2012)
Ann Oncol
, vol.23
, pp. 1693-1699
-
-
Stintzing, S.1
Fischer Von Weikersthal, L.2
Decker, T.3
Vehling-Kaiser, U.4
Jager, E.5
Heintges, T.6
Stoll, C.7
Giessen, C.8
Modest, D.P.9
Neumann, J.10
Jung, A.11
Kirchner, T.12
Scheithauer, W.13
Heinemann, V.14
-
14
-
-
69449100622
-
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
-
Moher D, Liberati A, Tetzlaff J, Altman DG: Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 2009;339:b2535.
-
(2009)
BMJ
, vol.339
, pp. b2535
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
-
15
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
-
Saltz LB, Clarke S, Diaz-Rubio E, Scheithauer W, Figer A, Wong R, Koski S, Lichinitser M, Yang TS, Rivera F, Couture F, Sirzen F, Cassidy J: Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008;26:2013-2019.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Diaz-Rubio, E.3
Scheithauer, W.4
Figer, A.5
Wong, R.6
Koski, S.7
Lichinitser, M.8
Yang, T.S.9
Rivera, F.10
Couture, F.11
Sirzen, F.12
Cassidy, J.13
-
16
-
-
77952591439
-
Magnitude of benefit of the addition of bevacizumab to first-line chemotherapy for metastatic colorectal cancer: Meta-analysis of randomized clinical trials
-
Loupakis F, Bria E, Vaccaro V, Cuppone F, Milella M, Carlini P, Cremolini C, Salvatore L, Falcone A, Muti P, Sperduti I, Giannarelli D, Cognetti F: Magnitude of benefit of the addition of bevacizumab to first-line chemotherapy for metastatic colorectal cancer: meta-analysis of randomized clinical trials. J Exp Clin Cancer Res 2010;29:58.
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 58
-
-
Loupakis, F.1
Bria, E.2
Vaccaro, V.3
Cuppone, F.4
Milella, M.5
Carlini, P.6
Cremolini, C.7
Salvatore, L.8
Falcone, A.9
Muti, P.10
Sperduti, I.11
Giannarelli, D.12
Cognetti, F.13
-
17
-
-
84920829728
-
Prognostic factors for survival with bevacizumab-based therapy in colorectal cancer patients: A systematic review and pooled analysis of 11,585 patients
-
Petrelli F, Coinu A, Cabiddu M, Borgonovo K, Lonati V, Ghilardi M, Barni S: Prognostic factors for survival with bevacizumab-based therapy in colorectal cancer patients: a systematic review and pooled analysis of 11,585 patients. Med Oncol 2015;32:456.
-
(2015)
Med Oncol
, vol.32
, pp. 456
-
-
Petrelli, F.1
Coinu, A.2
Cabiddu, M.3
Borgonovo, K.4
Lonati, V.5
Ghilardi, M.6
Barni, S.7
|