메뉴 건너뛰기




Volumn 23, Issue 7, 2012, Pages 1693-1699

FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer-subgroup analysis of patients with KRAS: Mutated tumours in the randomised German AIO study KRK-0306

Author keywords

Bevacizumab; Cetuximab; Colon cancer; First line; FOLFIRI; MCRC

Indexed keywords

BEVACIZUMAB; CETUXIMAB; FLUOROURACIL; FOLINIC ACID; IRINOTECAN;

EID: 84861318872     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdr571     Document Type: Article
Times cited : (93)

References (18)
  • 1
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • Van Cutsem E, Kohne CH, Hitre E et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009; 360: 1408-1417.
    • (2009) N Engl J Med , vol.360 , pp. 1408-1417
    • Van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 2
    • 59949091448 scopus 로고    scopus 로고
    • Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
    • Bokemeyer C, Bondarenko I, Makhson A et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 2009; 27: 663-671.
    • (2009) J Clin Oncol , vol.27 , pp. 663-671
    • Bokemeyer, C.1    Bondarenko, I.2    Makhson, A.3
  • 3
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 4
    • 77954372574 scopus 로고    scopus 로고
    • Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial
    • Ocvirk J, Brodowicz T, Wrba F et al. Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial. World J Gastroenterol 2010; 16: 3133-3143.
    • (2010) World J Gastroenterol , vol.16 , pp. 3133-3143
    • Ocvirk, J.1    Brodowicz, T.2    Wrba, F.3
  • 5
    • 79952768031 scopus 로고    scopus 로고
    • Cetuximab plus capecitabine and irinotecan compared with cetuximab plus capecitabine and oxaliplatin as first-line treatment for patients with metastatic colorectal cancer: AIO KRK-0104 - a randomized trial of the German AIO CRC Study Group
    • Moosmann N, Fischer von Weikersthal L, Vehling-Kaiser U et al. Cetuximab plus capecitabine and irinotecan compared with cetuximab plus capecitabine and oxaliplatin as first-line treatment for patients with metastatic colorectal cancer: AIO KRK-0104 - a randomized trial of the German AIO CRC Study Group. J Clin Oncol 2011; 29 (8): 1050-1058.
    • (2011) J Clin Oncol , vol.29 , Issue.8 , pp. 1050-1058
    • Moosmann, N.1    Fischer von Weikersthal, L.2    Vehling-Kaiser, U.3
  • 6
    • 79952153189 scopus 로고    scopus 로고
    • Randomized phase III study of 5-fluorouracil/ folinate/oxaliplatin given continuously or intermittently with or without cetuximab, as first-line treatment of metastatic colorectal cancer: the NORDIC VII Study (NCT00145314)
    • (Abstr LBA20). 35th ESMO Conference 2010, Edition. Milan, Italy
    • Tveit K, Guren T, Glimelius B et al. Randomized phase III study of 5-fluorouracil/ folinate/oxaliplatin given continuously or intermittently with or without cetuximab, as first-line treatment of metastatic colorectal cancer: the NORDIC VII Study (NCT00145314). Ann Oncol 2010; 21Suppl 8(Abstr LBA20). 35th ESMO Conference 2010, Edition. Milan, Italy
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. , pp. 8
    • Tveit, K.1    Guren, T.2    Glimelius, B.3
  • 7
    • 84864318952 scopus 로고    scopus 로고
    • The addition of cetuximab to oxaliplatinfluoropyrimidine chemotherapy in first-line advanced colorectal cancer in the MRC COIN trial: identification of potentially responsive subsets of patients
    • Maughan T, Adams R, Smith C et al. The addition of cetuximab to oxaliplatinfluoropyrimidine chemotherapy in first-line advanced colorectal cancer in the MRC COIN trial: identification of potentially responsive subsets of patients. Ann Oncol 2010; 21: 17-18.
    • (2010) Ann Oncol , vol.21 , pp. 17-18
    • Maughan, T.1    Adams, R.2    Smith, C.3
  • 8
    • 36048960109 scopus 로고    scopus 로고
    • Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study
    • Fuchs CS, Marshall J, Mitchell E et al. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study. J Clin Oncol 2007; 25: 4779-4786.
    • (2007) J Clin Oncol , vol.25 , pp. 4779-4786
    • Fuchs, C.S.1    Marshall, J.2    Mitchell, E.3
  • 9
    • 67650996205 scopus 로고    scopus 로고
    • Phase IV study of bevacizumab in combination with infusional fluorouracil, leucovorin and irinotecan (FOLFIRI) in firstline metastatic colorectal cancer
    • Sobrero A, Ackland S, Clarke S et al. Phase IV study of bevacizumab in combination with infusional fluorouracil, leucovorin and irinotecan (FOLFIRI) in firstline metastatic colorectal cancer. Oncology 2009; 77: 113-119.
    • (2009) Oncology , vol.77 , pp. 113-119
    • Sobrero, A.1    Ackland, S.2    Clarke, S.3
  • 10
    • 78149464410 scopus 로고    scopus 로고
    • A retrospective observational study on the safety and efficacy of first-line treatment with bevacizumab combined with FOLFIRI in metastatic colorectal cancer
    • Lopez R, Salgado M, Reboredo M et al. A retrospective observational study on the safety and efficacy of first-line treatment with bevacizumab combined with FOLFIRI in metastatic colorectal cancer. Br J Cancer 2010; 103: 1536-1541.
    • (2010) Br J Cancer , vol.103 , pp. 1536-1541
    • Lopez, R.1    Salgado, M.2    Reboredo, M.3
  • 11
    • 61449202998 scopus 로고    scopus 로고
    • The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer
    • Hurwitz HI, Yi J, Ince W et al. The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer. Oncologist 2009; 14: 22-28.
    • (2009) Oncologist , vol.14 , pp. 22-28
    • Hurwitz, H.I.1    Yi, J.2    Ince, W.3
  • 12
    • 79960146442 scopus 로고    scopus 로고
    • Impact of KRAS status on survival in patients ( pts.) with metastatic colorectal cancer (mCRC) undergoing bevacizumab (bev) containing chemotherapy regimen-analysis of the AIO Colorectal Cancer Study Group
    • (Abstr 585PD)
    • Reinacher-Schick A, Schmiegel W Impact of KRAS status on survival in patients ( pts.) with metastatic colorectal cancer (mCRC) undergoing bevacizumab (bev) containing chemotherapy regimen-analysis of the AIO Colorectal Cancer Study Group. Ann Oncol 2010; 21 (Suppl 8) (Abstr 585PD)
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 8 , pp. 2222
    • Reinacher-Schick, A.1    Schmiegel, W.2
  • 13
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study
    • Tournigand C, Andre T, Achille E et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004; 22: 229-237.
    • (2004) J Clin Oncol , vol.22 , pp. 229-237
    • Tournigand, C.1    Andre, T.2    Achille, E.3
  • 14
    • 77955611350 scopus 로고    scopus 로고
    • The German quality assurance system for the molecular-pathological detection of KRAS-mutations in colorectal cancer
    • (Abstr 4018). 2009 ASCO Annual Meeting
    • Jung A, Baretton G, Dietel M et al. The German quality assurance system for the molecular-pathological detection of KRAS-mutations in colorectal cancer. J Clin Oncol 2009; 27Suppl15s. (Abstr 4018). 2009 ASCO Annual Meeting
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • Jung, A.1    Baretton, G.2    Dietel, M.3
  • 15
    • 79956298812 scopus 로고    scopus 로고
    • Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status
    • Van Cutsem E, Kohne CH, Lang I et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J Clin Oncol 2011; 29: 2011-2019.
    • (2011) J Clin Oncol , vol.29 , pp. 2011-2019
    • Van Cutsem, E.1    Kohne, C.H.2    Lang, I.3
  • 16
    • 77956083776 scopus 로고    scopus 로고
    • Treatment of colorectal cancer with and without bevacizumab: a phase III study
    • Stathopoulos GP, Batziou C, Trafalis D et al. Treatment of colorectal cancer with and without bevacizumab: a phase III study. Oncology 2010; 78: 376-381.
    • (2010) Oncology , vol.78 , pp. 376-381
    • Stathopoulos, G.P.1    Batziou, C.2    Trafalis, D.3
  • 17
    • 78049341541 scopus 로고    scopus 로고
    • Association of KRAS p. G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab
    • De Roock W, Jonker DJ, Di Nicolantonio F et al. Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. JAMA 2010; 304: 1812-1820.
    • (2010) JAMA , vol.304 , pp. 1812-1820
    • De Roock, W.1    Jonker, D.J.2    Di Nicolantonio, F.3
  • 18
    • 79960892233 scopus 로고    scopus 로고
    • Influence of KRAS G13D mutations on outcome in patients with metastatic colorectal cancer (mCRC) treated with firstline chemotherapy with or without cetuximab
    • (Abstr 3511)
    • Tejpar S, Bokemeyer C, Celik I et al. Influence of KRAS G13D mutations on outcome in patients with metastatic colorectal cancer (mCRC) treated with firstline chemotherapy with or without cetuximab. J Clin Oncol 2011; 29 (Suppl) (Abstr 3511)
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL. , pp. 2222
    • Tejpar, S.1    Bokemeyer, C.2    Celik, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.