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Gastrointestinal dysfunction and enteric neurotoxicity following treatment with anti-cancer chemotherapeutic agent 5-Fluorouracil
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McQuade RM, Stojanovska V, Donald E, Abalo R, Bornstein JC, Nurgali K. Gastrointestinal dysfunction and enteric neurotoxicity following treatment with anti-cancer chemotherapeutic agent 5-Fluorouracil. Neurogastroenterol Motil 2016; 28: 1861–75.
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83755207115
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Characterization of motor patterns in isolated human colon: are there differences in patients with slow-transit constipation?
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Spencer NJ, Kyloh M, Wattchow DA et al. Characterization of motor patterns in isolated human colon: are there differences in patients with slow-transit constipation? Am J Physiol Gastrointest Liver Physiol 2012; 302: G34–43.
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Insights into the mechanisms underlying colonic motor patterns
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Spencer NJ, Dinning PG, Brookes SJ, Costa M. Insights into the mechanisms underlying colonic motor patterns. J Physiol 2016; 594: 4099–116.
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The morphology and projections of retrogradely labeled myenteric neurons in the human intestine
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Distribution and coexistence of peptides in nerve fibers of the external muscle of the human gastrointestinal tract
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W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity
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Huizinga JD, Thuneberg L, Kluppel M, Malysz J, Mikkelsen HB, Bernstein A. W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 1995; 373: 347–9.
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Bernstein, A.6
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8
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0345767046
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Migrating motor complexes do not require electrical slow waves in the mouse small intestine
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Spencer NJ, Sanders KM, Smith TK. Migrating motor complexes do not require electrical slow waves in the mouse small intestine. J Physiol 2003; 553: 881–93.
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Spencer, N.J.1
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Neurogenic slow depolarizations and rapid oscillations in the membrane potential of circular muscle of mouse colon
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11
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33645819191
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Anatomic modifications in the enteric nervous system of piebald mice and physiological consequences to colonic motor activity
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Ro S, Hwang SJ, Muto M, Jewett WK, Spencer NJ. Anatomic modifications in the enteric nervous system of piebald mice and physiological consequences to colonic motor activity. Am J Physiol Gastrointest Liver Physiol 2006; 290: G710–8.
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Ro, S.1
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12
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0015896424
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Electrical activity of the intestine of mice with hereditary megacolon and absence of enteric ganglion cells
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2+ waves in longitudinal and circular muscle during CMMCs and the consequences of rectal aganglionosis in mice
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2+ waves in longitudinal and circular muscle during CMMCs and the consequences of rectal aganglionosis in mice. Am J Physiol Gastrointest Liver Physiol 2007; 292: G546–55.
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Am J Physiol Gastrointest Liver Physiol
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Spencer, N.J.1
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15
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0034791023
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Effects of alosetron on spontaneous migrating motor complexes in murine small and large bowel in vitro
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Bush TG, Spencer NJ, Watters N, Sanders KM, Smith TK. Effects of alosetron on spontaneous migrating motor complexes in murine small and large bowel in vitro. Am J Physiol Gastrointest Liver Physiol 2001; 281: G974–83.
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Am J Physiol Gastrointest Liver Physiol
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Bush, T.G.1
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Smith, T.K.5
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16
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84880133859
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By what mechanism does ondansetron inhibit colonic migrating motor complexes: does it require endogenous serotonin in the gut wall?
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Spencer NJ, Nicholas SJ, Sia TC, Staikopoulos V, Kyloh M, Beckett EA. By what mechanism does ondansetron inhibit colonic migrating motor complexes: does it require endogenous serotonin in the gut wall? Neurogastroenterol Motil 2013; 25: 677–85.
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Neurogastroenterol Motil
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Spencer, N.J.1
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Beckett, E.A.6
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17
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80052297557
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Mechanisms underlying distension-evoked peristalsis in guinea pig distal colon: is there a role for enterochromaffin cells?
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Spencer NJ, Nicholas SJ, Robinson L et al. Mechanisms underlying distension-evoked peristalsis in guinea pig distal colon: is there a role for enterochromaffin cells? Am J Physiol Gastrointest Liver Physiol 2011; 301: G519–27.
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Am J Physiol Gastrointest Liver Physiol
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Spencer, N.J.1
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18
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84992507390
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Is there a role for endogenous 5-HT in gastrointestinal motility? How recent studies have changed our understanding
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Spencer NJ, Keating DJ. Is there a role for endogenous 5-HT in gastrointestinal motility? How recent studies have changed our understanding. Adv Exp Med Biol 2016; 891: 113–22.
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Adv Exp Med Biol
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Spencer, N.J.1
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19
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Electrophysiological and morphological changes in colonic myenteric neurons from chemotherapy-treated patients: a pilot study
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Carbone SE, Jovanovska V, Brookes SJ, Nurgali K. Electrophysiological and morphological changes in colonic myenteric neurons from chemotherapy-treated patients: a pilot study. Neurogastroenterol Motil 2016; 28: 975–84.
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Carbone, S.E.1
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20
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84911409312
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Identification of different types of spinal afferent nerve endings that encode noxious and innocuous stimuli in the large intestine using a novel anterograde tracing technique
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Spencer NJ, Kyloh M, Duffield M. Identification of different types of spinal afferent nerve endings that encode noxious and innocuous stimuli in the large intestine using a novel anterograde tracing technique. PLoS ONE 2014; 9: e112466.
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PLoS ONE
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Spencer, N.J.1
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Correlation of electrophysiological and morphological characteristics of enteric neurons in the mouse colon
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Nurgali K, Stebbing MJ, Furness JB. Correlation of electrophysiological and morphological characteristics of enteric neurons in the mouse colon. J Comp Neurol 2004; 468: 112–24.
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Nurgali, K.1
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Release of 5-Hydroxytryptamine from the mucosa is not required for the generation or propagation of colonic migrating motor complexes
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Keating DJ, Spencer NJ. Release of 5-Hydroxytryptamine from the mucosa is not required for the generation or propagation of colonic migrating motor complexes. Gastroenterology 2010; 138: 659–70.
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Gastroenterology
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Keating, D.J.1
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Neutrophil recruitment is critical for 5-fluorouracil-induced diarrhea and the decrease in aquaporins in the colon
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Sakai H, Sagara A, Matsumoto K et al. Neutrophil recruitment is critical for 5-fluorouracil-induced diarrhea and the decrease in aquaporins in the colon. Pharmacol Res 2014; 87: 71–9.
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